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Search Results: 1 - 10 of 127001 matches for " Mengqun Li "
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Modeling and Simulating of Uncertain Quality Abnormity Diagnosis
Shiwang Hou,Mengqun Li
Research Journal of Applied Sciences, Engineering and Technology , 2013,
Abstract: There is much fuzzy uncertain information during the diagnosis of quality abnormity. The effective utilization model of that can provide important decision-making support. In this study, we consider three main types of fuzzy production rules, which can be used in fuzzy quality abnormity diagnosis problem and their presentation models are constructed by use of Fuzzy Reasoning Petri Nets (FRPNs). Considering of the graphic representation and logic structure of FRPNs, we propose the method for simulating model using Matlab toolbox state flow. By establishing a corresponding relationship between FRPNs rules and state flow block diagram, three simulating models for the three corresponding FRPNs’ basic structure are developed. Finally, we give an application case of the proposed model. Taking place truth degree data of FRPNs as input, the diagnosis process and results can be shown dynamically in the state flow simulating model under Matlab environment. The result illustrated that the method proposed can give reliable information for process maintenance and abnormal causes’ location.
The Improvement of PAS-ELISA for Detection of CMV-free Germplasm in Larger Scale Micropropagation of Banana Plants

Huang Mengqun Liao Zhisong,

生物工程学报 , 1996,
Abstract: Owing to. the application of a routine ELISA test for detection of CMV-free germplasm in larger scale production of the micropropagated banana plants,we found severe false positive interference which caused high rate of germplasm loss. A modified test was developed by addition of sulphite in the solution for preparation of antigen. Statistical data showed that serious interference occured in the samples of the banana sucker and the first 1 - 2 generation of the micropropagated plantlet by using routine technique, and the false positive reaction were almost completely eliminated with the modified method. The dilution curve of purified CMV and TMV verified that there is no difference between the routine and modified methods in term of the sensitivity.
Re-Os isotopic compositions of late Mesozoic mafic rocks from southeastern coast of China

ZHOU JinCheng,JIANG ShaoYong,WANG XiaoLei,YANG JingHong,ZHANG MengQun,

岩石学报 , 2006,
Abstract: 从浙东、闽东南的早白垩世“双峰式火山岩”和“复合岩体”中选择了有代表性的玄武岩和角闪辉长岩,分离出钛-磁铁矿,进行Re—Os同位素分析。角闪辉长岩的γos(130Ma)为-83.7~ -47.1,其(^187 Os/^188 Os)。过低,为0.0667和0.0205。这低得不合理的(^187 Os/^188 Os)i表明成岩之后Re-Os体系可能受到扰动,某些地质过程导致外加Re的进入,使岩石的^187 Re/^188 Os比值偏高、(^187 Os/^188 Os);及γOs(t)值偏低。玄武岩的γOs(130Ma)=21.4—267.8,其(^187 Os/^188 Os)。为0.1531~0.4639。Re—Os、Sm—Nd同位素及微量元素地球化学研究表明,早白垩世玄武岩浆不是来自富集地幔,而是来自亏损的地幔源区,在其演化过程中经受了地壳岩石和熔体的混染。晚中生代时期,东南沿海“大陆弧”下的地幔可能不是富集的岩石圈地幔,具有亏损特性,因而是软流圈地幔。
Optimization of the Capsid of Recombinant Adeno-Associated Virus 2 (AAV2) Vectors: The Final Threshold?
George V. Aslanidi, Angela E. Rivers, Luis Ortiz, Liujiang Song, Chen Ling, Lakshmanan Govindasamy, Kim Van Vliet, Mengqun Tan, Mavis Agbandje-McKenna, Arun Srivastava
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0059142
Abstract: The ubiquitin-proteasome pathway plays a critical role in the intracellular trafficking of AAV2 vectors, and phosphorylation of certain surface-exposed amino acid residues on the capsid provides the primary signal for ubiquitination. Removal of several critical tyrosine (Y) and serine (S) residues on the AAV2 capsid has been shown to significantly increase transduction efficiency compared with the wild-type (WT) vectors. In the present study, site-directed mutagenesis of each of the 17 surface-exposed threonine (T) residues was conducted, and the transduction efficiency of four of these mutants, T455V, T491V, T550V, and T659V, was observed to increase up to 4-fold in human HEK293 cells in vitro. The most critical Y, S, and T mutations were subsequently combined, and the quadruple-mutant (Y444+500+730F+T491V) AAV2 vector was identified as the most efficient. This vector increased the transduction efficiency ~24-fold over the WT AAV2 vector, and ~2–3-fold over the previously described triple-mutant (Y444+500+730F) vector in a murine hepatocyte cell line, H2.35, in vitro. Similar results were obtained in murine hepatocytes in vivo following tail vein injection of the Y444+500+730F+T491V scAAV2 vector, and whole-body bioluminescence imaging of C57BL/6 mice. The increase in the transduction efficiency of the Y-T quadruple-mutant over that of the Y triple-mutant correlated with an improved nuclear translocation of the vectors, which exceeded 90%. These observations suggest that further optimization of the AAV2 capsid by targeting amino acid residues involved in phosphorylation may not be possible. This study has thus led to the generation of a novel Y444+500+730F+T491V quadruple-mutant AAV2 vector with potential for use in liver-directed human gene therapy.
Beneficial Experience from Teaching and Education to Research and Development  [PDF]
Li Li
Creative Education (CE) , 2012, DOI: 10.4236/ce.2012.37B039

Teaching and Education (T&E) constitute the most important activity in knowledge transfer from generation to generation. This can explain why government organizations consider the training of highly qualified personnel as one of the most important criteria in the selection of research and development (R&D) grant applications. A university professor should thus not only play the role of researcher, but also that of teacher. T&E and R&D combine to form an inseparable relationship for university professors. By shooting for excellence in T&E, we could get a new perception of a familiar field or initiate a brand new field altogether, which would in turn enhance our research. The quest for excellence in R&D leads to deeper and better understanding of materials taught, and progress in R&D enriches our T&E endeavors. Here, the author shares a beneficial experience from T&E to R&D.

A Causality Analysis of Coal Consumption and Economic Growth for China and India  [PDF]
Jinke Li, Zhongxue Li
Natural Resources (NR) , 2011, DOI: 10.4236/nr.2011.21007
Abstract: China and India are the two countries with the strongest economic growth in the world. Meanwhile they consume much of the global coal to fuel their economic development. With coal burning as a major factor contributing to global greenhouse gas emissions, China and India are confronted with a dilemma of economic growth and environment protection. Will coal consumption reduction cause economic shocks? Is there a causal relationship between coal consumption and economic growth in China and India? In this paper Granger causality tests were used to examine the relationship between coal consumption and GDP in China and India, using data for the period from 1965 to 2006. It was found that a unidirectional causality from GDP to coal consumption existed in China while a unidirectional causality from coal consumption to GDP did in India. Therefore, developing cleaner and more efficient technologies is essential to reduce their CO2 emissions to reach sustainable development.
An Investigation and Analysis of Information Overload in Manager's Work  [PDF]
Tao Li, Min Li
iBusiness (IB) , 2011, DOI: 10.4236/ib.2011.31008
Abstract: The problem of information overload in management field has been receiving increasing attention, while there are less empirical researches now. This paper proposes a conceptual model and some operational variables, in which information overload is as an intervening variable between the factors of causes and impacts. An investigation and analysis has been conducted from a selected sample of managers. This research suggests that work efficiency and work quality are both not strongly connected with information overload. We also find that the main causes of information overload are the work interruption and work time pressure but the amount of information.
Selection Advantage Pattern of International Sci-Tech Cooperation and Empirical Analysis  [PDF]
Li Li, Bin Yu
Journal of Service Science and Management (JSSM) , 2011, DOI: 10.4236/jssm.2011.41006
Abstract: Traditional international sci-tech cooperation theories mainly focus on the ability and advantage owned by cooperative parties, and according to which to guide the direction of international science and technology cooperation. Based on the integration of traditional theories of international science and technology cooperation and concrete practice, this paper proposes the selection advantage pattern and matching mechanism, which comprehensively take cooperator advantages, specification of project and change in circumstance into account and will play a guiding role in terms of determining the key country or region with which to prior carry out international science and technology cooperation. This paper also gives an analysis of the current status of industry development in Guangdong province and the research upon competitiveness evaluation of the world's related leading technology, puts forward corresponding countermeasures and suggestions on the science and technology cooperation patterns and approaches in terms of technological level and resources of Guangdong province.
Soil reinforcement by a root system and its effects on sediment yield in response to concentrated flow in the loess plateau  [PDF]
Peng Li, Zhanbin Li
Agricultural Sciences (AS) , 2011, DOI: 10.4236/as.2011.22013
Abstract: The importance of roots in soil conservation has long been underestimated due to a lack of sys-tematic studies conducted to evaluate root dis-tribution patterns and their effects on soil ero-sion. Current knowledge regarding root mor-phology and its impact on soil erosion by water is limited; therefore, detailed analysis of the role that root systems play in controlling soil ero-sion is needed. In this study, stratified runoff scouring at different soil depths in the field was conducted in a grassland area. The results in-dicated that both root biomass and soil wa-ter-stable aggregates decreased as soil depth increased at all three sites, while there was al-most no change in soil bulk density at 1.3g/cm3. Sediment yields under different runoff dis-charge at different sites showed similar trends, and the sediment yield increased as the soil depth increased at all three sites. Further analysis revealed that close relationships ex-isted between root biomass and the amount of water-stable aggregates and soil organic matter content, and that these factors greatly influ-enced soil erosion. Based on the data generated by the experiment, equations describing the relationship between sediment production at different soil depths and root biomass were determined.
Second-Order Volition and Conflict between Desires  [PDF]
Hengxi Li, Hengwei Li
Open Journal of Philosophy (OJPP) , 2012, DOI: 10.4236/ojpp.2012.21004
Abstract: In Freedom of the Will and the Concept of a Person, Harry Frankfurt put forward a theory that what is essential to be a person is second-order volition. The notion of second-order volition can be used as a key conceptual tool in understanding the conflict between desires. By means of the notion, this paper argues that the conflict between desires in our minds lies in the conflict between second-order volitions, other than the conflict between first-order desires. Based on this claim, this paper suggests that, due to the misunderstanding of the nature of the conflict between desires, the analysis of unwilling addict and wanton addict given by Frankfurt is thus wrong, and in his follow-up articles he made wrong description of the phenomenon concerning the conflict between desires.
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