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Search Results: 1 - 10 of 8689 matches for " Meliha TAN "
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Ototoxicity Probably Due To Isoniazid in a Patient Undergoing Hemodialysis
Journal of Neurological Sciences , 2008,
Abstract: Patients with end-stage renal failure (ESRF) have a high incidence of tuberculosis. Antituberculosis drug-induced ototoxicity may sometimes be a problem in these group of patients. Streptomycin is an antituberculosis drug with well-known ototoxic side effects. However, ototoxicity with combinations not including streptomycin has been reported only in a report in 7 of 42 ESRF patients undergoing hemodialysis and isoniazid has been suggested as a probable responsible drug which has well-known neurotoxic side effects. Here, we presented a 78- year-old man developed hearing loss who was on hemodialysis program and taking antituberculosis drug combination therapy including not streptomycin, but isoniazid, and the probable role of isoniazid in ototoxicity was discussed.
Human quadrupedalism is not an epiphenomenon caused by neurodevelopmental malformation and ataxia
Sibel Karaca,Meliha Tan,Uner Tan
Frontiers in Neurology , 2012, DOI: 10.3389/fneur.2012.00154
Abstract: Two cases with quadrupedal locomotion (QL) were presented. In both cases, cognitive and psychiatric functions were normal and, no neurological deficits were observed, except for a sequel paralysis of left leg in Case 2. It was suggested that human QL (1) should not be considered as an epiphenomenon caused by neurodevelopmental malformation and ataxia, but (2) may be considered as a re-emergence of the ancestral diagonal QL, and (3) it may spontaneously emerge in humans with entirely normal brains, by taking advantage of neural networks such as central pattern generators that have been preserved for about 400 million years.
Spinal MRI Findings of Guillain-Barré Syndrome
Ozlem Alkan,Tulin Yildirim,Naime Tokmak,Meliha Tan
Journal of Radiology Case Reports , 2009, DOI: 10.3941/jrcr.v3i3.153
Abstract: Guillain-Barré syndrome is a relatively common, acute, and rapidly progressive, inflammatory demyelinating polyneuropathy. The diagnosis is usually established on the basis of symptoms and signs, aided by cerebrospinal fluid findings and electrophysiologic criteria. Previously, radiologic examinations have been used only to rule out other spinal abnormalities. We report a case of systemic lupus erythematosus associated with Guillain-Barré syndrome with marked enhancement of nerve roots of the conus medullaris and cauda equina on MR imaging. These MR observations may help confirm the diagnosis of Guillain-Barré syndrome.
Ischemic stroke and subarachnoid hemorrhage due to spontaneous vertebral artery dissection: Three cases
Journal of Neurological Sciences , 2004,
Abstract: Dissection of vertebral arteries is increasingly being recognized as a cause of ischemic stroke and /or subarachnoid hemorrhage. Although head and neck trauma and primary diseases of arterial wall are predisposing factors, it can occur spontaneously. Headache and/ or neck pain with vertigo is important warning sign that may precede onset of stroke by several days. We described three patients with spontaneous vertebral artery dissection who had neck pain as presenting symptom. All patients had hypertension. Two of them (44 year-old male and 40 year- old female) had transient ischemic attack followed by stroke. 66-year old male patient had subarachnoid hemorrhage due to intracranial dissection of vertebral artery. We conclude that spontaneous vertebral artery dissection should be suspected in all patients presenting neck pain with posterior circulation ischemic stroke or SAH but without trauma history.
Late Onset Poststroke Seizures
Ba?ak Karakurum G?KSEL,Mehmet KARATA?,Meliha TAN,,Tülin YILDIRIM
Journal of Neurological Sciences , 2005,
Abstract: The most common cause of seizures is cerebrovascular disease in elderly population. Late onset seizures are not investigated as well as early onset seizures in patients with stroke. There is no common consensus about clinical, electrophysiological and radiological features of these seizures. In this study, 55 patients with late onset seizure who had stroke history were investigated. The 49 % of patients were women, the mean ages of patients were 63.9±9.2 years. The mean of duration between stroke and the first seizure was 30.4±36.8 months and the mean of following time was 14±13 months. The 89% of patients ischemic stroke and 11% of patients had hemorrhagic stroke. The lesion localizations were cortical in 17 (30.9%) patients, subcortical in 8 (14.5%) and cortico-subcortical in 29 (52.7%). As a result 84 % patients’ lesions were cortical localization. There were partial seizure in 39 (%70.9) patients, generalized tonic-clonic seizure in 16 (29.1%) patients. 43 (78%) patients had no seizure during antiepileptic therapy. 7 (12.7%) patients had seizure after beginning antiepileptic drug due to stopping drug, low blood level of drug and ineffectiveness of drug. 5 (9%) patients had not been given drug because of first seizure and no seizure during follow-up. In conclusion, the late onset poststroke seizures seem frequently in ischemic stroke, the reccurence rate was high and partial type seizures were more common than generalized and cortical localization was seen frequently. On the other hand, this condition has good prognosis.
Clinical and MRI Findings in Acute Cerebellitis
?zlem ALKAN,Meliha TAN,Yusuf Ziya DEM?RO?LU,Naime TOKMAK
Journal of Neurological Sciences , 2009,
Abstract: Acute cerebellitis is an inflammatory syndrome characterized by cerebellar dysfunction with acute onset. Here, the clinical findings, conventional and diffusion-weighted MR imaging features of five cases are reported. The most common clinical findings were headache, vertigo, nausea and vomiting. Neurological examination revealed cerebellar ataxia, nystagmus, dysmetria and dysdiadokinesia. Analysis of the CSF showed an elevated protein content and pleocytosis. Bilateral cerebellar cortical involvement and leptomeningeal enhancement along the folia represent the most common imaging presentations. Diffusion- weighted MR imaging showed restricted diffusion in two patients. In one patient, diffusion- weighted MR imaging did not show restricted diffusion. All patients were treated medically. Additionally, external ventricular drainage was performed in one patient. Follow-up MR imaging revealed cerebellar atrophy in 1 patient and gliosis in 2 patients. Two patients completely resolved after medical therapy. In conclusion, brain MR imaging and diffusion- weighted MR imaging are valuable imaging methods in diagnosis of cerebellitis, assessment of complications and sequel lesions.
G rme Engellilere Y nelik Kütüphanecilik Hizmetlerinde Türkiye'deki Son Geli meler: Gazi üniversitesi Merkez Kütüphanesi G rme Engelliler B lümü rne i
Meliha Kazak
Türk Kütüphanecili?i , 2008,
Abstract: Bu makalede g rme engellilerin kulland Braille alfabesinin tarih esi, g rme engellilere y nelik kütüphanecilik hizmetlerinde Türkiye 'deki son geli meler ve bu hizmetlerin verilmesinde kar la lan sorunlar ile züm nerileri yer almaktad r. Ayr ca Gazi üniversitesi G rme Engelliler B lümü 'nün kurulu u, geli imi, kullan c lar na sundu u hizmetler ve ileriye y nelik hedefleri anlat lmaktad r.
Impulse Control Disorders in a Group of University Exam Preparatory Course Students
N?ropsikiyatri Ar?ivi , 2011,
Abstract: Ob-jec-ti-ve: In recent years, interest on prevalence and comorbidity of impulse control disorders is constantly increasing. The aim of this study was to investigate the prevalence of impulse control disorders and its association with the existence of comorbid axis I disorders in young adult university exam preparatory course students. Met-hods: Two hundred and twenty-six preparatory course students aged 18-27 (mean age: 19.2) years were included in this study. Axis I diagnoses were evaluated using the Structured Clinical Interview for DSM-IV (SCID-I). Lifetime impulse control disorders were investigated using the modified version of Minnesota Impulsive Disorders Interview. Impulsivity was measured with the Barratt Impulsiveness Scale Version 11(BIS-11).Re-sults: The prevalence rate of all impulse control disorders in our sample was 23.4% (n=55). The most common impulse control disorder subtype was impulse control disorder not otherwise specified ICD-NOS (%16.8), followed by trichotillomania and intermittent explosive disorder. The most common ICD-NOS subtype was compulsive buying. There was no statistically significant difference between the diagnoses of axis I disorders in students with and without impulse control disorders. A statistically significant difference was found between groups with and without impulse control disorders in terms of total impulsivity and non-planning scores determined by the BIS-11. Conc-lu-si-on: Considering early age onset and decreasing prevalence with progressive aging, impulse control disorders are expected to be common in the young adult population. Prevalence rates determined at the end of this study were found to be higher in comparison with the peer group in literature. However, the prevalence rates obtained in our study may not be generalized tothe society because of the statistical limitation concerning our sample size. Large-scale, epidemiologic studies are required to be performed on this topic. (Arc-hi-ves of Neu-ropsy-chi-atry 2011;48: 238-42)
Congenital Leukemia Initially Presenting with Leukemia Cutis
Melike Sezgin Evim,Meliha Demiral
Güncel Pediatri , 2012,
Abstract: Introduction: Congenital leukemia represents less than 1% of childhood leukemia. Its prognosis is poor. Myeloid form is the most common type, and leukemia cutis has been observed in 25-30% of the patients. These skin lesions are defined as ‘blueberry muffin’ type which are blue-violaceous and usually multiple and diffuse nodules. Case Report: She had diffuse blue-violaceous nodules since birth. She hospitalized due to sepsis for 35 days. She was referred to our center with the suspicion of immune deficiency. The initial physical findings were severe pallor, diffuse blue-violaceous subcutanose nodules and hepatosplenomegaly. The leucocyte count was found 363 000/mm3. Acute monositer leukemia (AML-M5) was determined with morphologic and flow cytometric evaluation of the peripheral blood. Conclusion: Congenital leukemia must be thought in differential diagnosis from other underlying disease presenting with blueberry muffin skin lesions. (Jo-ur-nal of Cur-rent Pe-di-at-rics 2012; 10: 103-6)
Long-term Treatment in Bipolar Disorder
Meliha Zengin Eroglu,Nurgul Ozpoyraz
Psikiyatride Guncel Yaklasimlar , 2010,
Abstract: Although the importance of long-term prophylactic treatment is certain in bipolar disorder, there is stil debate on how to which patients and evaluate the treatment response. Efficacious long-term treatment can reduce morbidity and mortality significantly and improve quality of life of bipolar patients. The concept of ideal response should also be defined very clearly in order to discuss the difficulties of measuring the effectiveness of the prophylactic treatment. The aims of this paper are to determine whether our currently methods and criteria are valid, reliable and sensitive evaluating the efficacy of the treatment response and to briefly inform the clinicians about the drugs used in pharmacologic prophylaxis in accordance with relevant data.
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