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Hemodynamic of abdominal aortic aneurysm (AAA) and morphometryc characterization as a possible indicator of rupture Hemodinámica de aneurismas de aorta abdominal (AAA) y caracterización morfométrica como posible indicador de ruptura
Guillermo Vilalta Alonso,Félix Nieto Palomo,Melchor Rodríguez Madrigal,Laurentiu Lipsa
Revista Cubana de Ingeniería , 2010, DOI: 10.1234/rci.v1i3.25
Abstract: The rupture of abdominal aortic aneurysm (AAA) represents an important clinical event combining structural modifications that provoke a weakening of the arterial wall, coupled with the hemodynamic pressure acting on them. In an effort to increase understanding about this complex phenomenon, this paper studies the influence of abdominal aortic aneurysm asymmetry in the patterns of the main hemodynamics factors. Flow simulation in four 3D virtual AAA models with different asymmetry ranging from 0.2 to 0.8 were carried out under realistic pulsatile conditions to assess and identify regions with disturbed patterns flow and how it modifies the velocities fields and hemodynamic stress on the inside of the aneurysmatic sac. An explanation of the vortex structure changes and stress distribution during cardiac pulse, it is presented. The results obtained shown that the asymmetry is one of the main factors that influence the AAA rupture. On the other hand, the basis to establish a novel method, based on the morphometry of the AAA, to determine a numerical indicator characterizing the evolution and the rupture risk of aneurysm, regardless of size, it is approached. It is outlined the initial results of the validation, its current limitations and the future steps to improve the method. La ruptura de aneurismas de aorta abdominal (AAA) representan un evento clínico muy importante resultante de las modificaciones estructurales de la pared arterial que provocan un debilitamiento de la pared arterial combinadas con las presiones hemodinámicas que actúan sobre esta. En un esfuerzo por aumentar la comprensión sobre este complejo fenómeno, en el presente trabajo se estudia la influencia del grado de asimetría de los aneurismas de aorta abdominal, en los patrones de comportamiento de los principales factores hemodinámicos. Para esto, se han evaluado 4 modelos geométricos no realistas de AAA con diferentes grados de asimetría, sometidos a un flujo pulsatil fisiológicamente realista, con el objetivo de evaluar e identificar las regiones donde ocurren las principales perturbaciones en los patrones de flujo y como ésta modifica los campos de velocidades y de tensiones hemodinámicas, en el interior del saco aneurismático. Se presenta una explicación de las modificaciones de las estructuras vorticales y de la distribución de tensiones durante el ciclo cardíaco, cuyos resultados confirman que la asimetría de los aneurismas de aorta abdominal es uno de los principales factores que influyen en su ruptura. Por otro lado, en el trabajo se abordan las bases para establecer un método
Ruptura de aneurismas de aorta abdominal. Herramienta informática para su predicción
Vilalta-Alonso,Guillermo; Nieto,Félix; Vilalta-Alonso,José A.; Vaquero,Carlos; Lipsa,Laurentiu M.; Rodríguez-Madrigal,Melchor;
Ingenier?-a Mec??nica , 2011,
Abstract: the rupture of abdominal aortic aneurysm (aaa) represents an important clinical event due to its high mortality rate. currently the criteria to decide on the treatment of aaa patients are the peak transverse diameter and the growth rate which can be considered insufficient because they have not a reasonable physical base. the foundations for the design of pc software to predict, with sufficient accuracy to be clinically relevant, the risk of aaa rupture on patient-specific basis are defined in this paper. the software consists of 3 modules which are designed for processing all patient-specific information and integrate them through a model that interrelates the different nature (biological, structural and geometric) and scales (temporal and dimensional) biomechanical factors, in order to calculate a numerical and patient-specific indicator of the rupture risk. this tool should be an auxiliary element to physician in making decision on appropriate treatment decisions for patients with aneurysm.
Segmental Pigmentation Disorder with Congenital Heterochromia Iridis  [PDF]
Carmen Madrigal Díez, Sara Rodríguez Prado, José Héctor Fernández Llaca
Open Journal of Pediatrics (OJPed) , 2015, DOI: 10.4236/ojped.2015.53032
Abstract: We report the case of a 10-year-old girl with congenital complete heterochromia iridis and segmental pigmentation disorder in its hyperpigmented form. We have found no publication that mentions the combination of these 2 disorders.
Management for the White Shrimp (Litopenaeus vannamei) from the Southeastern Gulf of California through Biomass Models Analysis  [PDF]
Juan Madrid-Vera, Darío Chávez Herrera, Juan Melchor Aragón, Ricardo Meraz-Sánchez, José Alberto Rodríguez-Preciado
Open Journal of Marine Science (OJMS) , 2012, DOI: 10.4236/ojms.2012.21002
Abstract: Samples taken during the closed fishing seasons from 1992 to 2010 were analyzed at sea. These data along with the landing records for the fishing periods from 1992-1993 to 2009-2010 were used to allow the situation of Litopenaeus van-namei from the coasts of Sinaloa and Nayarit to be analyzed by means of stochastic models and by a graphic approach for the surplus biomass. Using the catch from 1993-1994 as a reference point and comparing this to the 2008-2009 catch revealed a stock decrease of about 65%. By taking into account the percentage contribution to total shrimp land-ings, these changes showed a decrease from 76% to 12%. There were changes between 2000 and 2001 when the fleet grew by 50%. Considering a 3600 t maximum sustained yield (MSY) in the series 1992-2010, 50% of the reports are lower. It is necessary to recover the stock.
Marcadores moleculares relacionados con cáncer de próstata: 3-nitrotirosina y expresión génica y protéica de la Mn-superóxido dismutasa (Mn-SOD)
Floriano-Sánchez,Esaú; Castro-Marín,Melchor; Cárdenas-Rodríguez,Noemí;
Archivos Espa?oles de Urología (Ed. impresa) , 2009, DOI: 10.4321/S0004-06142009000900003
Abstract: objectives: recent reports place prostate cancer (pca) as third cause of death in the world among males, in mexico it is the leading cause of male death. in this study, we studied molecular markers and one genetic marker related in tissues with pca and benign prostatic hyperplasia(bph): the mn-superoxide dismutase (mn-sod) gen and protein , prostate specific antigen (psa) and 3-nitrotyrosine (3-nt). it was evaluated if various markers of oxidative stress show altered expression in prostate cancer and bph. methods: 80 biopsies were obtained. the conditions to amplify and evaluate the immunoreactivity of the genes of interest (mn-sod and 3-nt) and the correlation between psa and mn-sod immunoreactivity in prostate cancer and benign prostatic hyperplasia were standardized. results: gene overexpression and mn-sod and 3-nt immunoreactivity were greater in prostate cancer with respect to the bph group. correlation between levels of psa and the mn-sod immunoreactivity was not observed. conclusions: the above results suggest that the parameters evaluated can be used as tumor markers making the determinations in biopsies of patients suspected of prostate cancer.
Synthesis of benzyl chlorides and cycloveratrylene macrocycles using benzylic alcohols under homogeneous catalysis by HCl/dioxane
Yolanda Marina Vargas-Rodríguez,Melchor Vargas,René Miranda,Bernardo Francisco
Organic Communications , 2012,
Abstract: The synthesis of benzyl chlorides, cyclic derivatives cyclotriveratrylene and cyclotripiperotrylene were carried out in using the HCl/dioxane system as a catalyst. The reaction proceeded with high selectivity and is sensitive to the number of alkyl and methoxy substituent on the aromatic ring.
Ecotoxicological evaluation of Pochonia chlamydosporia var. catenulata in terrestrial invertebrates
García L,Melchor G,Domínguez Y,Rodríguez H
RETEL : Revista de Toxicología en Línea , 2008,
Abstract: The strain IMI SD-187 of Pochonia chlamydosporia var. catenulata is suggested a new nematicidal agent and its effects on terrestrial organisms are therefore being investigated. Effects of compatibility on several species of fungus that share the same habitat have previously been found, including Pasteuria penetrans, Micorrhizas, Rhizobium, Pochonia chlamydosporia var chlamydosporia. The aim of this study was to examine a broad range of toxic effects and a wide concentration span to find the earliest and most relevant effects of this product on three invertebrates’ species.
El trabajo nocturno y sus implicaciones en la salud de médicos, enfermeras y oficiales de seguridad de los hospitales de la Caja Costaricense del Seguro Social en Costa Rica
Ana Imelda Barahona Madrigal,Ernesto José Vidaurre Mora,Fabricio José Sevilla Acosta,Jonathan Rodríguez Rodríguez
Medicina Legal de Costa Rica , 2013,
Abstract: En el presente trabajo se analiza la jornada laboral nocturna y las implicaciones que ésta tiene en la salud de los trabajadores de una institución que por sus características requiere atención las 24 horas, los siete días a la semana, como lo es la Caja Costarricense del Seguro Social. Para ello se escogió una muestra de médicos, enfermeras y oficiales de seguridad y se les interrogó acerca de las enfermedades que padecían, para tratar de establecer su relación con la jornada nocturna. This paper analyzes the night work and its implications on the health of workers in an institution which by its nature requires 24-hour care, seven days a week, as is La Caja Costarricense de Seguro Social. For this, it was chosen a sample of doctors, nurses and security officers and they were questioned about illnesses they had, to try to establish its relationship with the night shift.
Tabacosis, un cambio de terminología para un aumento de conciencia
Rodríguez-Madrigal,Alexis; Oguilve-Méndez,Miguel Angel;
Acta Médica Costarricense , 2011,
Abstract: in the absence of categorical definition of the real spanish academy, we have to lung disease obstructive disease (copd) is a preventable and treatable, with extra-pulmonary systemic disease, where pulmonary component is characterized by flow limitation air that is not fully reversible and is progressive.1 this is probably one of the medical definitions with greater number of positions and interests and is found which is undoubtedly and unfortunately, copd stands outside the medical community have no greater significance because find large numbers of patients daily carriers of this disease that have no real notion of suffering, doubt that many costs are clarified by the physician because of the cumbersome of its meaning, variety of symptoms and it causes many diseases. these vicissitudes in terms of causal pathology copd, are what have become the “box “ where placed various lung diseases that have no origin specifically, whether present or not airflow obstruction air, besides these problems of terminology, make it difficult to carry out literature searches by poor reception given to this término.
Angioplastía percutánea del tronco principal de la arteria coronaria izquierda
Siles Varela,Marco Antonio; Sáenz Madrigal,Eduardo; Rodríguez Guerrero,Daniel;
Revista Costarricense de Cardiología , 2008,
Abstract: percutaneous angioplasty of the left main coronary artery we describe the case of a 30 year old female patient with left main coronary artery disease, who was subject for an elective coronary angiogram. during the procedure, she became unstable electrically and hemodinamically, proceeding to place a coronary endoprothesis (stent) in the left main unprotected with success. after 5 months of follow-up, the patient remain asymptomatic.
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