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Search Results: 1 - 10 of 6088 matches for " Md. Ashraful Alam "
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Market Depth and Risk Return Analysis of Dhaka Stock Exchange: An Empirical Test of Market Efficiency
Md. Mahmudul Alam, Kazi Ashraful Alam, Md. Gazi Salah Uddin
ASA University Review , DOI: -
Abstract: It is customary that when security prices fully reflect all available information, the markets for those securities are said to be efficient. And if markets are inefficient, investors can use available information ignored by the market to earn abnormally high returns on their investments. In this context this paper tries to find evidence supporting the reality of weak-form efficiency of the Dhaka Stock Exchange (DSE) by examining the issues of market risk-return relationship and market depth or liquidity for DSE. The study uses a data set of daily market index and returns for the period of 1994 to 2005 and weekly market capital turnover in proportion of total market capital for the period of 1994 to 2005. The paper also looks about the market risk (systemic risk) and return where it is found that market rate of return of DSE is very low or sometimes negative. Eventually Capital Asset Pricing Model (CAPM), which envisages the relationship between risk and the expected rate of return on a risky security, is found unrelated in DSE market. As proper risk-return relationships of the market is seems to be deficient in DSE and the market is not liquid, interest of the available investors are bring into being very insignificant. All these issues are very noteworthy to the security analysts, investors and security exchange regulatory bodies in their policy making decisions to progress the market condition.
Naringin Improves Diet-Induced Cardiovascular Dysfunction and Obesity in High Carbohydrate, High Fat Diet-Fed Rats
Md. Ashraful Alam,Kathleen Kauter,Lindsay Brown
Nutrients , 2013, DOI: 10.3390/nu5030637
Abstract: Obesity, insulin resistance, hypertension and fatty liver, together termed metabolic syndrome, are key risk factors for cardiovascular disease. Chronic feeding of a diet high in saturated fats and simple sugars, such as fructose and glucose, induces these changes in rats. Naturally occurring compounds could be a cost-effective intervention to reverse these changes. Flavonoids are ubiquitous secondary plant metabolites; naringin gives the bitter taste to grapefruit. This study has evaluated the effect of naringin on diet-induced obesity and cardiovascular dysfunction in high carbohydrate, high fat-fed rats. These rats developed increased body weight, glucose intolerance, increased plasma lipid concentrations, hypertension, left ventricular hypertrophy and fibrosis, liver inflammation and steatosis with compromised mitochondrial respiratory chain activity. Dietary supplementation with naringin (approximately 100 mg/kg/day) improved glucose intolerance and liver mitochondrial dysfunction, lowered plasma lipid concentrations and improved the structure and function of the heart and liver without decreasing total body weight. Naringin normalised systolic blood pressure and improved vascular dysfunction and ventricular diastolic dysfunction in high carbohydrate, high fat-fed rats. These beneficial effects of naringin may be mediated by reduced inflammatory cell infiltration, reduced oxidative stress, lowered plasma lipid concentrations and improved liver mitochondrial function in rats.
Protein binding interaction of warfarin and acetaminophen in presence of arsenic and of the biological system
Md. Ashraful Alam,Riaz Uddin,Shamsul Haque
Bangladesh Journal of Pharmacology , 2008,
Abstract: Equilibrium dialysis was used to study in vitro binding of warfarin at physiological pH and temperature in bovine serum albumin (BSA) along with the increasing concentration of acetaminophen and there interaction with the protein in presence of arsenic. The free fractions were determined by UV spectrophotometric technique. The binding of warfarin to BSA depended on both drug and arsenic concentrations. Free warfarin concentration increased due to addition of acetaminophen which reduced the binding of warfarin to BSA. Free warfarin concentration also increased accordingly by increasing the concentra-tion of acetaminophen when only the BSA was present. When the binding site was blocked by sufficient amount of arsenic the increment of free concentration of warfarin decreased to a lower extent. This suggests that in the presence of arsenic the warfarin being slowly displaced from its high affinity binding site with increasing acetamino-phen concentration.
Estimation of Solar Radiation on Horizontal and Tilted Surface over Bangladesh  [PDF]
Mohammad Ashraful Islam, Md. Saiful Alam, Komol Kanta Sharker, Sanjoy Kumar Nandi
Computational Water, Energy, and Environmental Engineering (CWEEE) , 2016, DOI: 10.4236/cweee.2016.52006
Abstract: To estimate the monthly averaged solar radiations (global, diffuse and direct solar radiation) on horizontal surface and tilted surface over 10 stations (districts) in Bangladesh, thirty years monthly averaged data of various meteorological parameters namely the monthly averaged value of maximum temperature, minimum temperature, humidity and sunshine hours were used in this study. Assessment of the solar resources for the solar based renewable energy technologies of Bangladesh may be based upon this kind of measured data analyzed study. This study tried to estimate the monthly averaged solar radiation by presenting data in table and graph and finally analyze through equations and descriptions. Correlation between the measurements of monthly averaged solar radiation and the meteorological parameters was given for the selected 10 stations in Bangladesh. In conclusion, we tried to make a comparison among solar radiation on horizontal surface, fixed 20.83 ° (degree) optimal tilt angle and variable optimal tilt surface at Dhaka station.
Contribution of Rice Plants and Cover Crop Biomass Amended Soil on Methane Emission  [PDF]
Md Mozammel Haque, Jatish Chandra Biswas, Muhammad Ashraful Alam, Pil Joo Kim
American Journal of Climate Change (AJCC) , 2018, DOI: 10.4236/ajcc.2018.73029
Abstract: Rice plant and soil are playing vital role for produce of methane (CH4) emission from flooded rice soil. Contribution of rice plants and cover crop biomass amended soil on methane emission has not been yet studied under different cover crop biomass incorporated in paddy fields. Closed-chamber method was used to estimate CH4 emission rates during rice cultivation under soil plus rice plants and soil alone condition. Soil plus rice plants chambers 62 × 62 × 112 cm3 and soil alone chambers 20 × 20 cm2 were placed at the same time during rice cultivation (0 days after rice transplanting). Therefore, to evaluate the contribution of soil plus rice plants and soil alone on methane (CH4) emission under different rates of cover crop biomass incorporated soil during rice cultivation. Methane emission from soil plus rice plants increased up to 53 days after transplanting (DAT) and then it’s decreased and continued till harvesting. It was found that ca. 47% - 52% CH4 was mediated by rice plants and ca. 48% - 53% through rice soil alone under 12 Mg·ha-1 cover crop biomass incorporated treated plots. Whereas, only ca. 9% - 10% CH4 emission was mediated by rice plants and ca. 90% - 91% by rice soil alone when 0 and 3 Mg·ha-1 cover crop biomass was incorporated. Therefore, it could be concluded that rice soil alone was more influenced for CH4 emission than rice plants in paddy fields.
Phytochemical and Cytotoxic Investigation of Codiaeum variegatum Linn. Leaf
Nadia Saffoon,Md. Ashraful Alam,Golam Mezbah Uddin
Stamford Journal of Pharmaceutical Sciences , 2010,
In-vitro free radical scavenging activity of Ixora coccinea L
Moni Rani Saha,Md. Ashraful Alam,Raushanara Akter,Rumana Jahangir
Bangladesh Journal of Pharmacology , 2008,
Abstract: Antioxidant activity of the methanol extract of Ixora coccinea L. was determined by DPPH free radical scavenging assay, reducing power and total antioxidant capacity using phosphomolybdenum method. Preliminary phytochemical screening revealed that the extract of the flower of I. coccinea possesses flavonoids, steroids and tannin materials. The extract showed significant activities in all antioxidant assays compared to the standard antioxidant in a dose dependent manner and remarkable activities to scavenge reactive oxygen species (ROS) may be attributed to the high amount of hydrophilic phenolics. In DPPH radical scavenging assay the IC50 value of the extract was found to be 100.53 μg/mL while ascorbic acid had the IC50 value 58.92 μg/mL. Moreover, I. coccinea extract showed strong reducing power and total antioxidant capacity.
Powdery Mildew Resistance Genes in Wheat: Identification and Genetic Analysis
Md. Ashraful Alam,Fei Xue,Changyou Wang,Wanquan Ji
Journal of Molecular Biology Research , 2011, DOI: 10.5539/jmbr.v1n1p20
Abstract: Wheat powdery mildew, caused by Blumeria graminis f. sp. Tritici is one of the most devastating diseases of common wheat worldwide. To date, 41 loci (Pm1 to Pm45, Pm18=Pm1c, Pm22=Pm1e, Pm23=Pm4c, Pm31=Pm21) with more than 60 genes/alleles for resistance to powdery mildew have been identified and located on 18 different chromosomes in bread wheat. 29 resistance genes/alleles have been tagged with molecular markers such as restriction fragment length polymorphisms (RFLPs), random amplified polymorphic DNAs (RAPDs), amplified fragment length polymorphisms (AFLPs), sequence tagged sites (STS) and simple sequence repeats (SSRs), by using F2, back-cross populations, near-isogenic lines (NILs), doubled haploids (DH), recombinant inbred lines (RILs) or bulked segregant analysis (BSA). The detail information on chromosomal location, molecular markers linked to powdery mildew, mapping population and molecular mapping of powdery mildew resistance genes have been reviewed.
Comparison of Genetic Variability Between a Hatchery and a River Population of Rohu (Labeo rohita) by Allozyme Elctrophoresis
Mohammad Ashraful Alam,Mohammad Shariful Haque Akanda,Md. Muklesur Rahman Khan,Md. Samsul Alam
Pakistan Journal of Biological Sciences , 2002,
Abstract: In order to compare the genetic variability of a hatchery and a wild population of rohu (Labeo rohita), four enzyme systems, PGM, GPI, MDH and LDH were studied using horizontal starch gel electrophoresis. The enzymes were found to be encoded by 6 gene loci: Ldh-1*, Mdh-1*, Mdh-2*, Gpi-1*, Gpi-2* and Pgm*. Within the six loci, Gpi-2*, Mdh-1* and Pgm* were found to be polymorphic. The mean number of alleles per locus and heterozygosity values (observed and expected) in wild population were 1.660 and 0.217 respectively which were higher than those observed in hatchery population (1.500 and 0.142 respectively). The relatively lower level of genetic variability of hatchery population could be attributed to a limited number of founders of the hatchery stock and inbreeding.
In-vitro displacement interaction of atenolol and amlodipine on binding with bovine serum albumin when co-administered
Md. Ashraful Alam, Md. Abdul Awal, Mahbub Mostofa, Md. Kamrul Islam and Nusrat Subhan
Bangladesh Journal of Pharmacology , 2007,
Abstract: The binding of atenolol (selective β1-blocker) and amlodipine (calcium channel blocker) to bovine serum albumin (BSA) was studied by equilibrium dialysis method in order to have an insight into the binding chemistry of these two to BSA. Free atenolol concentration was increased due to addition of amlodipine which reduced the binding of the compounds to BSA. However, the free fraction was increased to a level as it was expected from direct competitive displacement while the free atenolol concentration was increased according to increasing the amlodipine concentration when only the BSA was present. The result obtained when the binding site was blocked by sufficient amount of amlodipine was that the increment of free concentration of atenolol was prominent. When no amlodipine was added the free concentration of atenolol was only 28% whereas this release was 93 % to 98.01% when amlodipine was added with increasing concentration.
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