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Search Results: 1 - 10 of 1101 matches for " Mbengue Mansour "
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Renal Disease among HIV Positive Patients in Senegal  [PDF]
Khodia Fall, Mouhamadou Moustapha Cissé, Ahmed Tall Lemrabott, Maria Faye, Mouhamed Cherif Dial, Atoumane Faye, Seynabou Fall, Moustapha Faye, Alex Keita, Mansour Mbengue, Seynabou Diagne, Niakhaleen Keita, Bacary Ba, Abdou Niang, Boucar Diouf, El Hadji Fary Ka
Open Journal of Nephrology (OJNeph) , 2017, DOI: 10.4236/ojneph.2017.74012
Abstract: Introduction: Renal disease (RD) in human immunodeficiency virus (HIV) infection is a decisive turning point in the development and prognosis of this disease. In Africa, the prevalence varies between 2.5% and 48.6%. In Senegal, little data are available in the literature. The objective of our study was to describe the epidemiological, clinical, paraclinical, therapeutic and progressional aspects in patients living with HIV (PLWHIV). Patients and methods: This was a retrospective, descriptive and analytical study carried out over a 10-year period in the Department of Internal Medicine and Nephrology at the Aristide Le Dantec Hospital in Dakar, Senegal. We included all 15-year old and above PLHIV with available CD4 count and viral load. Results: Out of 248 PLHIV, 32 had kidney disease (KD), which means a hospital prevalence of 12.9%. The mean age was 51.22 ± 10 years (extremes of 36 and 77 years) with a sex ratio (male/female) of 1.28. Renal signs were dominated by glomerular nephropathy syndrome. It was present at 80%. Tubulo-interstitial nephropathy syndrome and chronic uremic syndrome accounted for 6.25% and 3.1% of cases, respectively. Renal function Impairment was present in 21 patients with 18 cases of acute kidney injury (85.7%) and 3 cases of chronic renal failure (14.3%), including 2 in stage 5 of chronic kidney disease. Renal biopsy (RB) was indicated and performed in 20 (62.5%) patients with glomerular signs in 12 patients (60%). Glomerular lesions were dominated by focal and segmental glomerulosclerosis (FSGS) in 6 cases, membraneous nephropathy (MN) in 4 cases and minimal change disease (MCD) in 2 cases. Tubulo-interstitial and vascular lesions were present in 45% and 12.5% of cases, respectively. In highly active antiretroviral therapy (HAART), 12 (37.5%) patients had total remission, 9 (28.12%) had partial remission. One (3.12%) death from severe metabolic acidosis on chronic renal failure was deplored. Conclusion: This study illustrates the high prevalence of RD in PLHIV in our exercise context.
Intradialytic Hypertension: Prevalence and Associated Factors in Chronic Hemodialysis Patients in Senegal  [PDF]
Faye Moustapha, Lemrabott Ahmed Tall, Kane Yaya, Cisse Mouhamadou Moustapha, Seck Sidy Mohamed, Faye Maria, Daher Abdoul Karim Omar, Fall Khodia, Sakho Binta, Keita Rick Alex Ismael, Mbengue Mansour, Niang Abdou, Diouf Boucar, Ka Elhadji Fary
Open Journal of Nephrology (OJNeph) , 2018, DOI: 10.4236/ojneph.2018.82004
Abstract: Introduction: Intradialytic hypertension is defined as elevation of blood pressure to more than 10 mmHg in the post-dialysis period as compared to the pre-dialysis one. It is an important factor of morbidity and mortality in hemodialysis patients. The aim of our study is to assess the prevalence and associated factors of intradialytic hypertension. Patients and methods: This is a descriptive and analytical cross-sectional study that was conducted over a period of 3 weeks in the hemodialysis units of Aristide Le Dantec Hospital in Dakar and Regional Hospital Center in Ziguinchor. Chronic he-modialysis patients who are at least 18 years old and agreed to participate in study have been included. Patients who did not have 4 measures or those who decided to withdraw from the study were excluded. Intradialytic hypertension was restrained by an increase in systolic blood pressure immediately after the hemodialysis session > 10 mmHg compared to that recorded before session, with a repetition of this phenomenon for at least 4 hemodialysis sessions. Results: Our study included 539 hemodialysis sessions for 93 hemodialysis patients with a mean age of 48.72 ± 14.06 years and a sex ratio (M/F) of 1.21. The mean duration of dialysis was 64.22 ± 45.63 months. Hypertensive nephropathy was significantly common, noted in 38.7% (36 patients). Mean inter dialytic weight gain was 2.04 ± 1.06 kg, and the average dry weight was 62.71 ± 13.69 kg. The average hemoglobin level was 9.27 ± 1.91 g/dl. The mean albumin level was 35.4 ± 7.48 g/l. Nineteen (19) patients were administered erythropoietin stimulating agents (20.4%), and 59 patients were given antihypertensive drugs (63.4%). An elevation of more than 10 mmHg of post-dialysis BP compared to pre-dialysis was noted in 179 sessions, which is 33.2 per 100 hemodialysis sessions. IDH was noted in 21 patients, which represents 22.6%. The factors associated with IDH were as follows: high post-dialysis pulse pressure (PP) (p = 0.0008), pre-dialysis systolic-diastolic hypertension (p = 0.004), pre-dialysis pure systolic hypertension (p = 0.01), post-dialysis hypertension (p = 0.02), and hypoalbuminemia (p = 0.049). Conclusion: Although recognized for many years, the intradialytic hypertension is often neglected. However, it is common in our cohort of chronic hemodialysis with several associated factors. Its management is essential and will necessarily pass through adequate management of the blood volume.
Accidental Migration of a Guide Wire during Femoral Venous Catheterization for Hemodialysis: A Case Report  [PDF]
Faye Moustapha, Cisse Mouhamadou Moustapha, Faye Maria, Daher Abdoul Karim Omar, Lemrabott Ahmed Tall, Fall Khodia, Sakho Binta, Keita Alex, Mbengue Mansour, Niang Abdou, Diouf Boucar, Ka Elhadji Fary
Open Journal of Nephrology (OJNeph) , 2018, DOI: 10.4236/ojneph.2018.82005
Abstract: Femoral venous catheterization is the most used technic in emergency he-modialysis. Some uncommon mechanical complications can occur during a catheterization. We report the case of an accidental migration of a guide wire during the placement of a hemodialysis femoral catheter. The case of a patient admitted in the nephrology department at Aristide Le Dantec University Hospital for malignant hypertension was investigated. Emergency hemodialysis was indicated. Surgical extraction of the metal guide has been performed and the outcome was favorable.
Prognostic Aspects of Lupus Nephritis at Aristide Le Dantec University Hospital in Dakar  [PDF]
Mbengue Mansour, Faye Maria, Cissé Mouhamadou Moustapha, Lemrabott Tall Ahmed, Fall Khodia, Keita Alex, Faye Moustapha, Ba Bakary, Diagne Seynabou, Keita Niakhaleen, Ba Mamadou Aw, Dieng Ameth, Motula Latou Lot, Niang Abdou, Diouf Boucar, Ka El Hadji Fary
Open Journal of Nephrology (OJNeph) , 2018, DOI: 10.4236/ojneph.2018.84014
Abstract: Introduction: Kidney injury is common in the course of lupus and affects the functional and vital prognosis. The risk of progression to end-stage renal failure can reach 40% to 60%. Thus we carried out this work for the purpose of an evaluation of the renal and vital prognosis and to deduce the factors of poor prognosis. Patients and method: This was a retrospective, descriptive and analytical study conducted over a period of 10 years from January 1, 2007 to December 31, 2016, performed in the Nephrology Department of Aristide Le Dantec Hospital in Dakar. Patients with lupus nephritis were included. The studied parameters were epidemiological, clinical, paraclinical and progression. We had done a crossover of the patients to look for the factors of poor renal and vital prognosis. Results: Out of 93 cases of lupus patients, 64 were included, a prevalence of 69%. The mean age of the patients was 31.97 ± 10.44 years old. There were 81% women and 19% men, a sex ratio of 0.23. Class III was found in 24 cases (37.5%), Class IV in 20 cases (31.25%), Class V in 15 cases (23.4%), Class II in 4 cases (6.25%) and Class I in 1 case (1.6%). The combination of corticosteroids and immunosuppressants was used in 56.25% of cases. After a follow-up of six months, 19 patients were in complete remission, 21 had resistance and 9 had partial remission. Of the 21 patients who had resistance, 8 were in chronic renal failure. Death was observed in 5 patients and the causes were in 3 patients: pulmonary embolism, bacterial meningitis and pulmonary tuberculosis. The cause of death was unknown in 2 patients. The factors of poor renal prognosis were lymphopenia, the presence of anti-native DNA antibodies, nephrotic syndrome, microscopic hematuria, tubular atrophy and interstitial fibrosis. Risk factors affecting renal survival were the presence of native anti-DNA antibodies, microscopic hematuria, leukocyturia and the presence of a proliferative class. The factors of poor prognosis were renal failure, lymphopenia, nephrotic syndrome, glomerular sclerosis, arteriosclerosis, interstitial infiltration and tubular atrophy. Conclusion: The risk conferred by nephropathy is greater for proliferative glomerulonephritis; it is also correlated with the presence of persistent nephrotic syndrome or severe renal failure.
Multiple Myeloma Secondary to HIV Infection, Revealed by Renal Failure: About a Case  [PDF]
Mbengue Mansour, Cissé Mouhamadou Moustapha, Faye Maria, Lemrabott Tall Ahmed, Fall Khodia, Keita Alex, Faye Moustapha, Ba Bakary, Diagne Seynabou, Keita Niakhaleen, Ba Mamadou Aw, Dieng Ameth, Niang Abdou, Ka El Hadji Fary, Diouf Boucar
Open Journal of Nephrology (OJNeph) , 2019, DOI: 10.4236/ojneph.2019.91002
Abstract: Multiple myeloma is on the list of neoplasia that may be associated with human immunodeficiency virus infection. It is an affection that aggravates the prognosis in these particular patients. We present the case of a patient with multiple myeloma and HIV infection, revealed by renal failure. This was a 59-year-old patient who was received to the Department of nephrology for renal failure associated with severe aregenerative pancytopenia. In etiological investigations, multiple myeloma associated with HIV1 infection was found. The evolution was unfavorable, marked by the death of the patient caused by digestive haemorrhage before the start of antiretroviral treatment and chemotherapy.
Optimization of the Bitumen Content of a Basaltic Semi-Granular Bituminous Concrete  [PDF]
Souleymane Mbengue, Djibril Sow, Ibrahima Khalil Cisse
Open Journal of Civil Engineering (OJCE) , 2018, DOI: 10.4236/ojce.2018.84032
Abstract: Various studies have been conducted in the past by researchers who have proposed diverse solutions to control the premature degradation noted on flexible pavements. It turns out that the binder content remains a parameter so far not mastered and its optimization remains an imperative to produce a quality mix capable of meeting the technical and economic requirements sought in a formulation study. This article mainly aimed to optimize the hydrocarbon binder content of a 0/14 granular class semi-granular bituminous concrete using the Marshall and Duriez method. In the first part of the study, the different constituents were characterized according to the standards in force. The second allowed to describe the methodology used to determine the mixture and calculated the theoretical binder content. A theoretical mixture, entering the reference zone was defined at first. Following the characterization of the mixture in the laboratory, the granulometry curve of the mixture was inserted into the reference zone. This mixture was then preserved for the rest of the study. Then, it was theoretically determined bitumen contents ranging from 5.13% to 5.75% for wealth modules ranging from 3.3% to 3.7%. Thus, the Marshall method was used to characterize the performance of the mixture as a function of the binder content. The results obtained led to the selection of two grades of binders 5.13% and 5.28% for the study of water resistance using the Duriez method. On the basis of the results obtained on the Duriez test, the mixture with a binder content of 5.28% satisfies a good part of the criteria selected. This content corresponds to a wealth module of 3.4%.
Spatial Modeling of Residential Crowding in Alexandria Governorate, Egypt: A Geographically Weighted Regression (GWR) Technique  [PDF]
Shawky Mansour
Journal of Geographic Information System (JGIS) , 2015, DOI: 10.4236/jgis.2015.74029
Abstract: Despite growing research for residential crowding effects on housing market and public health perspectives, relatively little attention has been paid to explore and model spatial patterns of residential crowding over space. This paper focuses upon analyzing the spatial relationships between residential crowding and socio-demographic variables in Alexandria neighborhoods, Egypt. Global and local geo-statistical techniques were employed within GIS-based platform to identify spatialvariations of residential crowding determinates. The global ordinary least squares (OLS) modelassumes homogeneity of relationships between response variable and explanatory variablesacross the study area. Consequently, it fails to account for heterogeneity of spatial relationships. Local model known as a geographically weighted regression (GWR) was also employed using the sameresponse variable and explanatory variables to capture spatial non-stationary of residentialcrowding. A comparison of the outputs of both models indicated that OLS explained 74 percent ofresidential crowding variations while GWR model explained 79 percent. The GWR improvedstrength of the model and provided a better goodness of fit than OLS. In addition, the findings of this analysis revealed that residential crowding was significantly associated with different structural measures particularly social characteristics of household such as higher education and illiteracy. Similarly, population size of neighborhood and number of dwelling rooms were found to have direct impacts on residential crowding rate. The spatial relationship of these measures distinctly varies over the study area.
Temperature Effects on the Equation of State and Symmetry Energy: A Critique  [PDF]
Hesham Mansour
Open Journal of Microphysics (OJM) , 2018, DOI: 10.4236/ojm.2018.84004
The investigation of strongly interacting systems ranges from matter inside atomic nuclei to matter under extreme conditions in astrophysics. These systems require the introduction of nuclear forces and a systematic many-body approach to solve the strong interaction particles. Understanding the behavior of infinite nuclear matter provides a path to predict the properties of neutron stars and gives insights to astrophysical phenomena. Three-nucleon forces have to be considered when studying nuclear systems, because their impact is necessary to reproduce properties of nuclei and to correctly obtain the neutron drip line. Moreover, they are needed to predict the empirical saturation properties of infinite nuclear matter. The self-consistent Green’s Function approach paves the way for an improved Ab initio analysis of nuclear matter, thereby providing the basis for the equation of state of neutron stars and supernova explosions.
On the Preon Model  [PDF]
Hesham Mansour
Open Journal of Microphysics (OJM) , 2019, DOI: 10.4236/ojm.2019.92002
One of the fundamental questions is that “what the matter is composed of?” In 1897, atoms are known as the basic building blocks of matter. In the year 1911, Ernest Rutherford demonstrated that when alpha particles are scattered on a thin gold foil that the atom is composed of mostly empty space with a dense core at its center which is called the nucleus. Thereafter, protons and neutrons were discovered. In 1956, McAllister and Hofstadter published experimental results of elastic scattering of the electrons from a hydrogen target which revealed that the proton has an internal structure. In 1964, Gell-Mann (and independently) Zweig proposed that nucleons are composed of point-like particles which are called quarks. These quarks are postulated to have spin-1/2, fractional electric charge. Combinations of different flavors of quarks yield protons and neutrons which belong to the type of particles called baryons (built up from three quarks) and mesons as (quark and an antiquark). These two groups of particles are categorized as hadrons. The quarks showed further decay properties which suggested that they have a substructure.
Efficacy of Different Fungicides against Mango Anthracnose in Senegalese Soudanian Agroclimate  [PDF]
Papa Madiallacke Diedhiou, Yaya Diallo, Rokhaya Faye, Abdou Aziz Mbengue, Abdou Sene
American Journal of Plant Sciences (AJPS) , 2014, DOI: 10.4236/ajps.2014.515236

Anthracnose is the one of the most devastating diseases of mango produced in the southern part of Senegal. The field trials against post harvest rot due to anthracnose took place in three orchards over two production seasons, in 2009 and 2010. Three systemic fungicides (thiophanate methyl, azoxystrobin and myclobutanyl) and one contact fungicide (mancozeb) were tested for their efficacy. The first treatments in 2009 took place in the rainy season, while 20% of mangoes on trees exhibited anthracnose lesions. At ripening stage, 100% of fruits from non treated control mango trees were affected by anthracnose and got rotten, while between 73.2% and 80% of mangoes ripened free of disease when treated with thiophanate methyl. With the treatment with azoxystrobin, between 46.6% and 60% of fruits were not infected. Treatment with myclobutanyl was less effective. This level of effectiveness was clearly improved in 2010 by preventive spraying, days ahead of onset of the rainy season, before the appearance of anthracnose symptoms on fruits. The level of effectiveness was higher respectively for thiophanate methyl (between 96% and 100% of fruits not infected) and azoxystrobin (between 84% and 96% of fruits not infected).

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