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Search Results: 1 - 10 of 151950 matches for " Max Andresen H "
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Ventilación mecánica en el paciente con lesión cerebral aguda
Tomicic F,Vinko; Andresen H,Max;
Revista médica de Chile , 2011, DOI: 10.4067/S0034-98872011000300016
Abstract: in about20% of patients admitted to an intensive care unit (icu) the indica-tion of mechanical ventilation (mv) is a neurological disease. these patients have a prolonged mv stay and high mortality. the appropriate use of mv in patients with acute brain injury (abi) is critica! considering that mv by itself is oble to induce or worsen an underlying lung injury. patients with abi have a higher risk to develop pulmonary complications. during endotracheal intubation the activation of airway reflexes should beprevented, because they may increase intracranialpressure. tracheostomy is indicated to improve airway management and it is performed in about 33% of these patients. indications for mv are loss of spontaneous respira-tory effort, changes in lung compliance, gas exchange impairment and ventilatory failure due to muscle fatigue or neuromuscular junction dysfunction. during mv, hypoxemia should be avoided. the pc02 level has a critica! role in cerebral blood flow regulation; therefore a normal pco must be maintained in order to guarantee an optimal cerebral blood flow. despite that, hypocapnia has been used in patients with increased intracranial pressure, at the present it is not recommended. its use should be limited to the emergency management of intracranial hypertension, while the underlying cause is beingtreated. non-conventional ventilatory modes asprone position ventilation, high-frequency oscillatory ventilation and extracorporeal c02 removal can be used in patients with abi. all ofthem have specific risks and should be employed cautiously this paper reviews upper airway management and mv in patients with acute brain injury.
Ventilación mecánica en el paciente con lesión cerebral aguda Mechanical ventilation in patients with acute brain injury
Vinko Tomicic F,Max Andresen H
Revista médica de Chile , 2011,
Abstract: In about20% of patients admitted to an Intensive Care Unit (ICU) the indica-tion of mechanical ventilation (MV) is a neurological disease. These patients have a prolonged MV stay and high mortality. The appropriate use of MV in patients with acute brain injury (ABI) is critica! considering that MV by itself is oble to induce or worsen an underlying lung injury. Patients with ABI have a higher risk to develop pulmonary complications. During endotracheal intubation the activation of airway reflexes should beprevented, because they may increase intracranialpressure. Tracheostomy is indicated to improve airway management and it is performed in about 33% of these patients. Indications for MV are loss of spontaneous respira-tory effort, changes in lung compliance, gas exchange impairment and ventilatory failure due to muscle fatigue or neuromuscular junction dysfunction. During MV, hypoxemia should be avoided. The pC0(2) level has a critica! role in cerebral blood flow regulation; therefore a normal pCO must be maintained in order to guarantee an optimal cerebral blood flow. Despite that, hypocapnia has been used in patients with increased intracranial pressure, at the present it is not recommended. Its use should be limited to the emergency management of intracranial hypertension, while the underlying cause is beingtreated. Non-conventional ventilatory modes asprone position ventilation, high-frequency oscillatory ventilation and extracorporeal C02 removal can be used in patients with ABI. All ofthem have specific risks and should be employed cautiously This paper reviews upper airway management and MV in patients with acute brain injury.
El aniversario 140 de la Revista Médica de Chile
Reyes B,Humberto; Andresen H,Max; Palma H,Joaquín;
Revista médica de Chile , 2012, DOI: 10.4067/S0034-98872012000100001
Abstract: revista médica de chile was founded in 1872 and thus is one of the oldest medical journals being published since the 19th century. the sponsoring institution -"sociedad médica de santiago", founded in 1869- initially was the only scientific society in chile, gathering medical doctors from every existing specialty. with the splitting of independent organizations representing specific specialties, including subspecial-ties of internal medicine, sociedad médica de santiago focused its scope of action to become the "chilean society of internal medicine". its official journal -revista médica de chile- is currently a general and internal medicine journal that also publishes articles on scientific and technological advances in many fields of medicine and health sciences. while initially all authors were chilean, the journal is now open to submissions from abroad and since the year 2000 articles are published in english when the local language of authors is not spanish. the number of articles received determines an increasing administrative and editorial burden and, together with the high cost of publishing, will require changes in publication policies. the journal will participate in continuing medical education programs as soon as reaccreditation of medical specialties becomes officially organized in chile.
Estrés oxidativo en el paciente crítico
Andresen H,Max; Regueira H,Tomás; Leighton,Federico;
Revista médica de Chile , 2006, DOI: 10.4067/S0034-98872006000500015
Abstract: among critically ill patients, several physio-pathological processes such as global and local hypo-perfusion, hypoxia, endothelial injury and acidosis have been associated with the production and release of large amounts of reactive oxygen species (ros) in a non regulated fashion. although in physiologic conditions ros influence intracellular processes and participate in the defense against infectious organism, in critically ill conditions they are associated with potential oxidative damage over cellular structures and with persistent activation of the inflammatory response. mechanisms associated with oxidative damage are activation of the macrophage-monocyte system and neutrophils, ischemia-reperfusion events and intracellular ros production. endogenous compounds, mainly enzymes, and dietary components act as antioxidant. several studies show that in critically ill patients increase levels of ros or reduction of antioxidant levels are related to disease severity. in animal models of critical diseases, antioxidant therapy has shown to reduce mortality. nevertheless, there are few studies in humans that only show improvements in hemodynamic variables, reduction in inflammatory mediators levels, decreases in oxidized compounds and that suggest a lower incidence of multiple organ failure
El Comité Asesor Internacional, desde el a?o 2009
Reyes B,Humberto; Palma H,Joaquín; Andresen H,Max;
Revista médica de Chile , 2009, DOI: 10.4067/S0034-98872009000500001
Abstract: starting in 2001, revista médica de chile has received advice and contributions from eight distinguished physicians from belgium, italy, spain and the u.s.a., nominated members of its international advisory board. a list of their contributions appears in the references section of this editorial. the editors have considered opportune to renew this committee. two of the previous members will remain in office because of their frequent and outstanding contributions. seven new members have been selected among prominent physicians and scientists working out of chile, with brilliant academic and professional careers, who have established regular contacts with different chilean societies in the fields of internal medicine and its subspecialties. the editors expect to receive their advice and contributions to stimulate progress in a journal that currently has expanded its presence in the international literature in internal and general medicine, and in related specialties and biomedical science.
Los criterios de autoría de trabajos científicos: traducción al castellano de la versión más reciente del documento "Requisitos Uniformes para los Manuscritos Sometidos a Revistas Biomédicas" Authorship criteria: A translation into Spanish from the 2001 updated version of the document "Uniform Requirements for Manuscripts Submitted to Biomedical Journals"
Humberto Reyes B,Joaquín Palma H,Max Andresen H
Revista médica de Chile , 2002,
Abstract:
Actualización de los criterios de autoría en las publicaciones biomédicas Authorship Criteria in Biomedical Articles
Humberto Reyes B,Joaquín Palma H,Max Andresen H
Revista médica de Chile , 2002,
Abstract: In the year 2000, a previous Editorial in this journal reviewed the criteria for authorship as defined by experienced authors and editors, discussed in selected references from the biomedical literature. An emphasis was given to the definition of authorship stated in the available 1997 version of the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals". After that Editorial was published, an updated version of the "Uniform Requirements" established important changes in their criteria; eg. Participation of each author in the work should permit them to take public responsibility for "appropiate portions of the content"; and acquisition of data was added as an acceptable alternative in the first requisite for authorship. These and other changes should be difussed to prospective authors, particularly in multicentric studies usually leading to multiauthorship. This new Editorial and a translation into Spanish of the authorship criteria contained in an updated (2001) version of the "Uniform Requirements" are included in this issue of Revista Médica de Chile with the purpose of stimulating authors and readers to think in their implications (Rev Méd Chile 2002; 135: 1083-6)
Estrés oxidativo en el paciente crítico Oxidative stress in critically ill patients
Max Andresen H,Tomás Regueira H,Federico Leighton
Revista médica de Chile , 2006,
Abstract: Among critically ill patients, several physio-pathological processes such as global and local hypo-perfusion, hypoxia, endothelial injury and acidosis have been associated with the production and release of large amounts of reactive oxygen species (ROS) in a non regulated fashion. Although in physiologic conditions ROS influence intracellular processes and participate in the defense against infectious organism, in critically ill conditions they are associated with potential oxidative damage over cellular structures and with persistent activation of the inflammatory response. Mechanisms associated with oxidative damage are activation of the macrophage-monocyte system and neutrophils, ischemia-reperfusion events and intracellular ROS production. Endogenous compounds, mainly enzymes, and dietary components act as antioxidant. Several studies show that in critically ill patients increase levels of ROS or reduction of antioxidant levels are related to disease severity. In animal models of critical diseases, antioxidant therapy has shown to reduce mortality. Nevertheless, there are few studies in humans that only show improvements in hemodynamic variables, reduction in inflammatory mediators levels, decreases in oxidized compounds and that suggest a lower incidence of multiple organ failure
Medicina Basada en Evidencia, en la Revista Médica de Chile Evidence Based Medicine, in Revista Médica de Chile
Humberto Reyes B,Joaquín Palma H,Max Andresen H
Revista médica de Chile , 2003,
Abstract: Since the beginning of the 20th century, the principles of the experimental method in biological sciences have been progressively applied in biomedical and clinical research. After the pioneering work of AB Hill et al, biostatistics became a fundamental tool in the appraisal of new therapeutic agents or methods, and of diagnostic tests. From 1990 on, Evidence based Medicine has been added to it. This journal opens in this issue a section containing critical analysis of articles published in the medical literature deserving the attention of its readers. However, as several other medical journals have stressed, we recommend that the conclusions of these analysis should not be used as a substitute for clinical judgment and they do not represent an official position of our journal. Revista Médica de Chile welcomes the new Section and invites contributions to it (Rev Med Chile 2003; 131: 835-6
El manejo editorial de los manuscritos recibidos en la Revista Médica de Chile The editorial handling of manuscripts submitted to Revista Médica de Chile
Humberto Reyes B,Joaquín Palma H,Max Andresen H
Revista médica de Chile , 2004,
Abstract:
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