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Search Results: 1 - 10 of 896 matches for " Masaru Aoyagi "
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A Case of Sublingual Dermoid Cyst: Extending the Limits of the Oral Approach
Nobuo Ohta,Tomoo Watanabe,Tsukasa Ito,Toshinori Kubota,Yusuke Suzuki,Akihiro Ishida,Seiji Kakehata,Masaru Aoyagi
Case Reports in Otolaryngology , 2012, DOI: 10.1155/2012/634949
Abstract: We present the case of a dermoid cyst with an oral and a submental component in a 21-year-old Japanese woman who presented with complaints of a mass in the oral cavity and difficulty in chewing and swallowing solid foods for about 2 years. MRI shows a 55 × 65 mm well-circumscribed cystic mass extending from the sublingual area to the mylohyoid muscle. Under general anesthesia and with nasotracheal intubation, the patient underwent surgical removal of the mass. Although the cyst was large and extending mylohyoid muscle, intraoral midline incision was performed through the mucosa overlying the swelling and the cyst was separated from the surrounding tissues with appropriate traction and countertraction and successfully removed without extraoral incision. Oral approach in surgical enucleation is useful procedure to avoid cosmetic problems in large and extending mylohyoid muscle cyst.
A Case of Sublingual Dermoid Cyst: Extending the Limits of the Oral Approach
Nobuo Ohta,Tomoo Watanabe,Tsukasa Ito,Toshinori Kubota,Yusuke Suzuki,Akihiro Ishida,Seiji Kakehata,Masaru Aoyagi
Case Reports in Otolaryngology , 2012, DOI: 10.1155/2012/634949
Abstract: We present the case of a dermoid cyst with an oral and a submental component in a 21-year-old Japanese woman who presented with complaints of a mass in the oral cavity and difficulty in chewing and swallowing solid foods for about 2 years. MRI shows a 55 × 65?mm well-circumscribed cystic mass extending from the sublingual area to the mylohyoid muscle. Under general anesthesia and with nasotracheal intubation, the patient underwent surgical removal of the mass. Although the cyst was large and extending mylohyoid muscle, intraoral midline incision was performed through the mucosa overlying the swelling and the cyst was separated from the surrounding tissues with appropriate traction and countertraction and successfully removed without extraoral incision. Oral approach in surgical enucleation is useful procedure to avoid cosmetic problems in large and extending mylohyoid muscle cyst. 1. Introduction Sublingual epidermoid and dermoid cysts are benign lesions encountered throughout the body, with 7% occurring in the head and neck area and 1.6% within the oral cavity [1–5]. They represent less than 0.01% of all oral cavity cysts [6–9]. The pathogenesis of midline cysts of the floor of the mouth is not well established, and dysontogenetic and thyroglossal anomaly theories have been suggested [1–9]. In fact, dermoid cysts occur primarily in the oral cavity, and the most common location in the head and neck is the external third of the eyebrow [1–9]. Dermoid cysts generally present with slow and progressive growth, and even if they are congenital, they are possible in the second or third decade of life [7–9]. The treatment of dermoid cysts of the floor of the mouth is surgical; the approach can be either intraoral or extraoral, depending on the localization and size of the mass. Cysts are classified into three types by localization: (1) sublingual, (2) submental, and (3) submandibular cysts. Oral approach is usually applied for small sublingual cyst. The extraoral incision is preferred in submental and large sublingual cysts. Dermoid cysts usually present early in life as asymptomatic masses; they may reach a large size and involve more than one anatomical area, including that near the hyoid bone [1–9]. Such a swelling on the floor of the mouth can occasionally cause serious problems with swallowing and speaking [1–9]. Here, we outline a case of giant sublingual dermoid cyst in a 21-year-old woman that was successfully removed by oral approach without extraoral incision. 2. Case Report A 21-year-old Japanese woman was referred to our otolaryngology department
Intravesical Non-Alkalinized Lidocaine Instillation for Interstitial Cystitis/Bladder Pain Syndrome Patients  [PDF]
Teiichiro Aoyagi, Masaaki Tachibana
Open Journal of Urology (OJU) , 2012, DOI: 10.4236/oju.2012.24040
Abstract: Purpose: The effectiveness of daily or weekly instillation of non-alkalinized lidocaine for patients suffering interstitial cystitis and/or bladder pain syndrome was evaluated retrospectively. Patients and methods: Five female patients (40 - 71 years old) diagnosed as interstitial cystitis by cystoscopic findings and a 68 year-old bladder pain syndrome patient were enrolled. All patients, having interstitial cystitis, had undergone hydrodistention therapy previously and had not improved their symptoms by empirical therapies. Daily or weekly (upon their severity of symptoms) intravesical instillation of 20 ml of 4% non-alkalinized (pH 6.0 - 7.0) lidocaine solution was performed for several times, and patients were asked to keep them in the bladder as long as two hours each time. Previous medications such as anti-cholinergic drugs and analgesics were continued according to patient's requirements and symptoms. The treatment effect was evaluated comparing O'Leary-Sant Symptom Index for interstitial cystitis patients and visual analog pain scale before and after the series of lidocaine therapies. Results: Instillation was made 6 to 16 times. Patients with interstitial cystitis improved their symptoms from O'Leary-Sant Symptom Index 17.5 to 10, Problem Index from 14.8 to 6 in an average. Crouching pain disappeared in all these patients after the instillation therapy. Severe interstitial cystitis findings on cystoscopy disappeared completely in one patient after the therapy. One patient having bladder pain syndrome reduced her analgesics use, and bladder-filling pain decreased from 7 to 3 as a visual analog scale score. One patient complained palpitation at 11th instillation and abandoned treatment thereafter, otherwise, none of these patients showed side effect concerning lidocaine toxicity. Conclusions: Intravesical non-alkalinized lidocaine instillation therapy for interstitial cystitis/bladder pain syndrome patients were an easy, safe and effective treatment.
Clinical and Pathological Characteristics of Organized Hematoma
Nobuo Ohta,Tomoo Watanabe,Tsukasa Ito,Toshinori Kubota,Yusuke Suzuki,Akihiro Ishida,Masaru Aoyagi,Atsushi Matsubara,Kenji Izuhara,Seiji Kakehata
International Journal of Otolaryngology , 2013, DOI: 10.1155/2013/539642
Abstract: Objective. To study the clinical and pathological characteristics of patients with organized hematoma with malignant features in maxillary sinuses. Subjects and Methods. This was a retrospective study of five patients who were treated surgically for organized hematoma. The preoperative CT and MRI findings were studied clinically. The expressions of CD31, CD34, and periostin in surgical samples were investigated by immunohistochemistry. Results. The clinical features of organized hematoma, such as a mass expanding from the maxillary sinus with bone destruction, resembled those of maxillary carcinoma. However, CT and MRI provided sufficient and useful information to differentiate this condition from malignancy. Surgical resection was the first-line treatment because of the presence of a firm capsule. Characteristic histopathological findings were a mixture of dilated vessels, hemorrhage, fibrin exudation, fibrosis, hyalinization, and neovascularization. The expressions of periostin, CD31, and CD34 were observed in organized hematoma of the maxillary sinus. Conclusion. The expressions of periostin, CD31, and CD34 were observed in organized hematoma of the maxillary sinus. Organized hematoma is characterized pathologically by a mixture of bleeding, dilated vessels, hemorrhage, fibrin exudation, fibrosis, hyalinization, and neovascularization. CT and MRI show heterogeneous findings reflecting a mixture of these pathological entities. 1. Introduction Nonneoplastic hemorrhagic lesions causing mucosal swelling and bone destruction can develop in the maxillary sinus. This type of lesion was reported in the Japanese literature in 1917 as a “blood boil of the maxillary sinus” by Tadokoro and is comparatively well known in Japan as one of the differential diagnoses of maxillary carcinoma. However, in the English literature, this type of lesion tends to be referred to as hemangioma of the maxillary sinus, organized hematoma of the maxillary sinus, or organized hematoma of the maxillary sinus mimicking tumor [1–8]. Although their clinical manifestations are very similar, the relationships between these entities have not been described. We recently resected five such lesions and examined the associated clinical and histological features. Histologically, a combination of dilated vessels, hemorrhage, fibrin exudation, fibrosis, hyalinization, and neovascularization was characteristic. The lesion mimicked not only hematoma but also hemangioma. Therefore, either of the terms hemangioma or hematoma reflects the complete histological picture. In this paper, we report the
Consideration on Singularities in Learning Theory and the Learning Coefficient
Miki Aoyagi
Entropy , 2013, DOI: 10.3390/e15093714
Abstract: We consider the learning coefficients in learning theory and give two new methods for obtaining these coefficients in a homogeneous case: a method for finding a deepest singular point and a method to add variables. In application to Vandermonde matrix-type singularities, we show that these methods are effective. The learning coefficient of the generalization error in Bayesian estimation serves to measure the learning efficiency in singular learning models. Mathematically, the learning coefficient corresponds to a real log canonical threshold of singularities for the Kullback functions (relative entropy) in learning theory.
A Network of Oscillators for Retrieving Phase Information
Toshio Aoyagi
Physics , 1994, DOI: 10.1103/PhysRevLett.74.4075
Abstract: We propose a network of oscillators to retrieve given patterns in which the oscillators keep a fixed phase relationship with one another. In this description, the phase and the amplitude of the oscillators can be regarded as the timing and the strength of the neuronal spikes, respectively. Using the amplitudes for encoding, we enable the network to realize not only oscillatory states but also non-firing states. In addition, it is shown that under suitable conditions the system has a Lyapunov function ensuring a stable retrieval process. Finally, the associative memory capability of the network is demonstrated numerically.
Tips for Office-Based Transurethral Biopsy and Fulguration as a Treatment of Tiny Bladder Tumors  [PDF]
Teiichiro Aoyagi, Isao Kuroda, Masaaki Tachibana
Open Journal of Urology (OJU) , 2013, DOI: 10.4236/oju.2013.36047
Abstract:

Among the patients who underwent outpatient cystoscopy as a follow up of bladder cancer, quite a few patients are observed tiny papillary lesions suspicious for tumor recurrence. Transurethral biopsy and/or resection under spinal or general anesthesia in a hospitalized setting are the usual procedures for this kind of patients, even though these procedures are simple and brief. We tried transurethral biopsy and fulguration as a treatment for very small bladder tumor in an outpatient setting and here describe tips for these procedures. Olympus CYF-VA flexible cystoscope, a 3 Fr. diathermy probe, monopolar electrosurgical unit were used. No additional anesthetics except for 10 ml of 2% Xylocaine gel applied to (male patient’s) urethra as an initial flexible cystoscopic procedure, was required for tumor treatment. Distilled water was used as an irrigation fluid. Experienced tips of the procedures to avoid tumor recurrence are as follows: tumor should be one location, size of the tumor should be less than 5 mm, bladder should be washed several times after the fulguration with hundreds ml of distilled water. We conclude that outpatient biopsy and fulguration for tiny bladder tumor is effective and less invasive procedure as a treatment of bladder cancer patients.

Sarcomatoid carcinoma of the penis  [PDF]
Isao Kuroda, Takuya Ishida, Teiichiro Aoyagi
Case Reports in Clinical Medicine (CRCM) , 2014, DOI: 10.4236/crcm.2014.31003
Abstract:

We encountered a 63-year-old male with a sarcomatoid carcinoma of the penis accompanied by metastasis to the bilateral inguinal lymph nodes and lungs. He noticed a penile mass, but neglected it. The mass rapidly increased in size, forming an ulcer, and began to disintegrate. He visited our hospital 4 months after noticing the mass. After cystostomy and blood transfusion, surgical resection was performed. A diagnosis of a squamous cell carcinoma with a sarcomatoid carcinoma of the penis was made. After the operation, best supportive care (BSC) was selected. We made efforts to maintain his quality of life (QOL), and he died 3 months after the operation.

How Do Foreign and Domestic Demand Affect Exports Performance? An Econometric Investigation of Indonesia’s Exports  [PDF]
Rudy Rahmaddi, Masaru Ichihashi
Modern Economy (ME) , 2012, DOI: 10.4236/me.2012.31005
Abstract: This paper explores the impacts of foreign and domestic demand on Indonesia’s exports within demand and supply frameworks using aggregate data of 1971 - 2007. In contrast to many previous studies employing a single equation model, the paper investigates such relationship by dealing with plausible simultaneity between quantity and price within demand and supply of exports using a simultaneous equation framework, which also enables one to distinct between pull (foreign demand) and push (cost) factors of exports. To capture effects of secular and cyclical movements on exports, we dissect income variables into trend and business cycle as proxies of productive capacity and capacity utilization rate, respectively. Our results suggest that both demandand supply-price elasticity are elastic, and secular and cyclical movements may have contrast effects on exports. The production capacity is positively attributed to exports performance, while the capacity utilization negatively affects exports, which confirms the customary version of domestic-demand pressure hypothesis. Some economic shocks and policies also play roles in determining exports performance. All estimated coefficients are statistically stable over the period under study. The findings draw policy implications namely the importance of price-based policy, provision of adequate and sound infrastructures, and further development of human capital-based industrialization.
Recent advances in choledochal cysts  [PDF]
Hiroyuki Tadokoro, Masaru Takase
Open Journal of Gastroenterology (OJGas) , 2012, DOI: 10.4236/ojgas.2012.24029
Abstract: Choledochal cysts are a congenital anomaly, and they show dilatation of the intra- or extrahepatic biliary tree. These cysts are uncommon in Western countries, but are not rare in Asian countries. Choledochal cysts are classified into five groups based on location or shape of the cysts. Types I and IV-A cysts are the most common types, which are associated with anomalous pancreaticobiliary junction (APBJ), but other cysts are not associated with APBJ. Types I and IV-A cysts appear to belong to a different category from other cysts embryologically. Type I and IV-A cysts accompany anomalies of the pancreas. Type I and IV-A cysts might occur when left ventral anlage persists, and with disturbed recanalization of the common bile duct. Endoscopic retrograde cholangiopancreatography is the gold standard for detecting APBJ, but it is an invasive procedure. Magnetic resonance cholangiopancreatography (MRCP) is a non-invasive imaging tool for detecting pancreatic and biliary trees. MRCP is the first-choice modality for diagnosing choledochal cysts and APBJ in pediatric patients. Cystoenterostomy is been performed because of high complication and mortality rates. Complete excision of the cysts with Roux-en-Y hepatojejunostomy is a standard procedure for choledochal cysts to prevent postoperative complications, including development of cancer. In this study, we review classification, pathogenesis, diagnosis, and treatment of types I and IV-A choledochal cysts.
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