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Search Results: 1 - 10 of 1327 matches for " Masaki Yazawa "
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Comparison of Malignant Bone Treatments for Reuse  [PDF]
Masaki Yazawa, Taisuke Mori, Kazuo Kishi
Surgical Science (SS) , 2013, DOI: 10.4236/ss.2013.41009

The After cancer resection including bone, recently, bone resected with cancer has been considered to be reusable. We newly examined superheated steam treatment for bone reuse and compared it to existing treatments. Forty male C3H/HeN mice were used to establish a model of mandible invasion by oral squamous cell carcinoma (OSCC). The mice were sacrificed to harvest the tumor invading mandible bone. The resected tumor with mandible bone was treated by one of four kinds of treatment, no treatment for the control, the Pasteur method, liquid nitrogen treatment, micro-wave treatment and superheated steam treatment. After each treatment, the resected bone was transplanted into a syn-geneic mouse back. Eight weeks after transplantation, the mice were sacrificed and evaluated pathologically. Grafted tumors showed recurrence: 7/7 in the control, 6/8 in the liquid nitrogen treatment, 1/8 the microwave treatment and 2/8 the superheated steam treatment groups. No recurrence, on the other hand, was observed in the Pasteur method (0/8). The Pasteur method is a good treatment to remove malignant cells.

Reconstruction of Hemipelvectomy Defect Using a Fillet Flap with Femoral Periosteum  [PDF]
Masaki Yazawa, Tsuyoshi Kaneko, Sumitoshi Katsumata, Kazuo Kishi
Surgical Science (SS) , 2010, DOI: 10.4236/ss.2010.12010
Abstract: Backgrounds: Reconstruction after hemipelvectomy is very important for rehabilitation into society. The pelvis plays an important role for support of the intra-abdominal organs. Methods: We operated 3 cases using fillet flaps with the femoral periosteum for reconstruction of hemipelvectomy defect. Results: It is useful to elevate the flap all around with the femoral periosteum, because the periosteum can be sutured to supporting pelvic structures with the aim to support intra-abdominal organs. Conclusion: Without alternative supports for the bony pelvis, pelvic reconstructions are at risk for hernia and it may be difficult for outpatients to fit their habiliments after radical cure. The rigid support for the intra-abdominal organs occurs in association with the suture pelvic and femoral periosteum.
Rhinoplasty for Saddle Nose with Sarcoidosis  [PDF]
Masaki Yazawa, Hayato Nagashima, Katsuya Suzuki, Kazuo Kishi
Surgical Science (SS) , 2015, DOI: 10.4236/ss.2015.66035
Abstract: Background: Cases of acquired saddle nose have been reported; however, reports of sarcoidosis with acquired saddle nose are very rare. The main cause of sarcoidosis is estimated to be an abnormal immune reaction rather than infection. Aim: Rhinoplasty using an autologous rib was planned and performed without plate fixation. Case Presentation: Our patient was diagnosed with sarcoidosis at the age of 25 years. She developed nasal congestion and rhinitis at the age of 42 years. Her nose began to show the saddle nose deformity at the age of 43 years. A rhinoplasty using an autologous rib was performed without plate fixation. Conclusion: After the operation, her nose maintained a favorable shape without sarcoidosis worsening. This use of rhinoplasty for treating saddle nose possibly prevents the worsening of sarcoidosis.
Treatment of Craniomaxillofacial Fibrous Dysplasia  [PDF]
Takayuki Okumoto, Masaki Yazawa, Yoshikazu Inoue, Kazuo Kishi
Surgical Science (SS) , 2015, DOI: 10.4236/ss.2015.66036
Abstract: Fibrous dysplasia is a benign osseous disease, although radical resection is commonly recommended because of the possibility of recurrence or malignant change. However, radical resection is undesirable, particularly in the maxillofacial region, because facial bones are difficult to replace in an aesthetically-pleasing manner after radical excision. In our department, conservative shaving, as reported by Chen and Noordhoff, is used to reduce tumor volume while maintaining facial aesthetics that are as normal as possible. We have experienced eight cases of craniomaxillofacial fibrous dysplasia and successfully applied conservative shaving to the maxillofacial lesions. These cases have exhibited no recurrence, and their facial contours have improved remarkably.
Basic Fibroblast Growth Factor for Treatment of Onychomadesis with Delayed Regrowth of the Nail
Tomito Oji,Masaki Yazawa,Kazuo Kishi
Case Reports in Dermatological Medicine , 2013, DOI: 10.1155/2013/214810
Abstract: Onychomadesis usually arises from an inflammation of the paronychium or as a result of blisters and hemorrhaging under a nail that has been struck or compressed. No documented interactions between basic fibroblast growth factor (bFGF) and onychomadesis have hitherto been reported. This case report describes a 25-year-old woman with onychomadesis following infection of the ingrown nail of her left thumb. After ten months of observation with no treatment showed no regrowth of her left thumbnail, the external use of bFGF and antibiotic ointment was started. One month later, nail regrowth was observed up to the halfway point of the nail bed, and after treatment for three months, the regrown nail reached the top of the nail bed. Both thumbnails now looked identical. This case suggests that external use of bFGF can promote nail regrowth in cases of onychomadesis with delayed regrowth of the nail. 1. Introduction Onychomadesis usually arises from an inflammation of the paronychium or blisters and hemorrhage under the nail caused by a blow or compression. Systemic diseases, such as hand-foot-and-mouth disease, pemphigus vulgaris, and Stevens-Johnson syndrome, occasionally result in onychomadesis. Normally, simple observation or supportive treatment of inflammation will promote the regrowth of the fallen nail. However, in cases where nail regrowth does not occur, the condition tends to be refractory. Hitherto, there have been no effective treatments that promote the regrowth of fallen nails. In this paper, we report a notable case of onychomadesis after infection of an ingrown nail, in which the external use of basic fibroblast growth factor (bFGF; Trafermin; Fiblast Spray) and antibiotic ointment (Bacitracin-fradiomycin sulfate; Baramycin) led to normal nail regrowth. 2. Case Presentation The case was a 25-year-old woman. She was a nursery teacher and routinely washed her hands many times daily. She had no previous medical history and was taking no medications or dietary supplements. Her left thumb had an ingrown nail, but she had not had it examined in a clinic, since it showed no troublesome symptoms. However, after her ingrown nail became infected, it presented with pain, swelling, and discharge of pus. Those symptoms continued for a month, after which the nail fell off the nail bed. She went to a clinic to have her left thumbnail examined at that time, but underwent observation rather than receiving treatment due to the expectation that it would spontaneously regenerate. No further infections flared up, but no regrowth of her left thumbnail was seen in four
Treatment of Congenital Absence of the Mammary Gland
Masaki Yazawa,Mika Watanabe,Masahiro So,Kazuo Kishi
Case Reports in Surgery , 2013, DOI: 10.1155/2013/676573
Usefulness of Choline-PET for the detection of residual hemangiopericytoma in the skull base: comparison with FDG-PET
Shin Ito, Junkichi Yokoyama, Hitoshi Yoshimoto, Masaki Yazawa, Kubota Kazuo, Makoto Hanaguri, Shinichi Ohba, Mitsuhisa Fujimaki, Katsuhisa Ikeda
Head & Face Medicine , 2012, DOI: 10.1186/1746-160x-8-3
Abstract: The patient was a 51-year-old man with repeated recurrent hemangiopericytoma in the skull base. We performed Choline-PET in this patient after various treatments and compared findings with those of FDG-PET.Choline accumulated in this tumor, but FDG did not accumulate. We diagnosed this tumor as residual hemangiopericytoma and performed the resection of the residual tumor. FDG-PET is not appropriate for skull base tumor detection because uptake in the brain is very strong.We emphasize the usefulness of Choline-PET for the detection of residual hemangiopericytoma in the skull base after various treatments, compared with FDG-PET.Positron emission tomography (PET) has been successfully used for the diagnosis of head and neck cancer and 18-fluorodeoxyglucose (FDG) is the most commonly used PET tracer and FDG-PET offers the most effectiveness for imaging various tumors. However, this technique is not appropriate for skull base tumor detection because FDG uptake in the brain is very strong. Recently 11 C-choline was developed as a new PET tracer. Here we report the effectiveness of this tracer for PET imaging of residual hemangiopericytoma in the skull base. Hemangiopericytoma is a very rare tumor in the head and neck region. This tumor sometimes relapse in the base of skull. Repeated surgeries could cause severe postoperative complications. Therefore, accurate diagnosis of recurrent tumor is strongly required now.A 51-years-old Japanese man presented with a tumor in the right temple and underwent resection of the tumor at a medical college hospital in 1979. The histological diagnosis was hemangiopericytoma. Thereafter, he demonstrated local recurrence many times, underwent resection 5 times and embolization was performed 2 times. Despite these treatments, this tumor relapsed in the temple again and was treated by irradiation (total 61.8 Gy) in November 2002. However, the tumor appeared to persist and multiple lung metastases were detected. After 4 months, he consulted our
Reciprocal functional interactions between the brainstem and the lower spinal cord
Itaru Yazawa
Frontiers in Neuroscience , 2014, DOI: 10.3389/fnins.2014.00124
Abstract: The interplay of the neuronal discharge patterns regarding respiration and locomotion was investigated using electrophysiological techniques in a decerebrate and arterially perfused in situ mouse preparation. The phrenic, tibial, and/or peroneal nerve discharge became clearly organized into discharge episodes of increasing frequency and duration, punctuated by periods of quiescence as the perfusion flow rate increased at room temperature. The modulated sympathetic tone induced by the hyperoxic/normocapnic state was found to activate the locomotor pattern generator (LPG) via descending pathways and generate a left and right alternating discharge during discharge episodes in the motor nerves. The rhythm coupling of respiration and locomotion occurred at a 1:1 frequency ratio. Although the phrenic discharge synchronized with the tibial discharge at all flow rates tested, the time lag between peaks of the two discharges during locomotion was ≈400 ms rather than ≈200 ms, suggesting spinal feedback via ascending pathways. The incidence of the phrenic and tibial discharge episodes decreased by ≈50% after spinalization at the twelfth thoracic cord and the respiratory rhythm was more regular. These results indicate that: (i) locomotion can be generated in a hyperoxic/normocapnic state induced by specific respiratory conditions, (ii) the central mechanism regarding entrainment of respiratory and locomotor rhythms relies on spinal feedback via ascending pathways, initiated by the activated LPG generating locomotion, and (iii) the increase in respiratory rate seen during locomotion is caused not only by afferent mechanical and nociceptive inputs but also by impulses from the activated spinal cord producing a locomotor-like discharge via ascending pathways.
Seismicity in the Antarctic Continent and Surrounding Ocean  [PDF]
Masaki Kanao
Open Journal of Earthquake Research (OJER) , 2014, DOI: 10.4236/ojer.2014.31002

Seismicity in the Antarctic and surrounding ocean is evaluated based on the compiling data by the International Seismological Centre (ISC). The Antarctic continent and surrounding ocean have been believed to be one of the aseismic regions of the Earth for many decades. However, according to the development of Global Seismic Networks and local seismic arrays, the number of tectonic earthquakes detected in and around the Antarctic continent has been increased. A total of 13 seismicity areas are classified into the Antarctic continent (3 areas) and oceanic regions within the Antarctic Plate (10 areas). In general, seismic activity in the continental areas is very low in Antarctica. However, a few small earthquakes are identified. Wilkes Land in East Antarctica is the most tectonically active area in the continent, with several small earthquake events having been detected during the last four decades. In the oceanic region, in contrast, seismic activity in the area of 120?-60? W sector is three times higher than that in the other oceanic areas. This may be considered to be involved in a tectonic stress concentration toward the Easter Island Triple Junction between the Antarctic Plate, the Pacific Plate and the Nazu- ca micro-Plate. Three volcanic areas, moreover, the Deception Island, the Mts. Erebus and Melbourn, are also found to be high seismic activities in contrast with surrounding vicinity areas.

Statistics of Seismic Tremors with Harmonic Overtones Recorded at Syowa Station, Antarctica: October 2014-March 2015  [PDF]
Masaki Kanao
International Journal of Geosciences (IJG) , 2017, DOI: 10.4236/ijg.2017.86046
Abstract: During the period from October 2014 to March 2015, a total number of 82 seismic tremors and 66 ice-quakes were identified in both three-component short-period seismographs (HES) and broadband seismographs (STS-1) at Syowa Station (SYO), Antarctica. Statistics of the number of these tremors indicated that many tremors were likely to occur when large increases in temperature and/or wind speed during the period. This implied that the rapid increase in temperature enhanced a melting speed of cryosphere environment with generating seismic energy; the tremors were also excited by stormy conditions, associated with interactive resonance between sea-ices and oceanic swells. The characteristic tremors of harmonic overtones with strong amplitudes were explained by repetitive sources, suggesting inter-glacial asperities such as the collision of icebergs and fast sea-ice, calving of glaciers/ice-streams at the coastal environment of Antarctica. These high amplitude tremors occurred independently from other majority types of events, characterized by non-linear, small amplitude and weak signals at the stormy condition and rapid increase in temperature.
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