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Search Results: 1 - 10 of 5832 matches for " Masahiro Tanaka "
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Three Generations or More for an Attractive Gravity?
Masahiro Tanaka
Physics , 1995, DOI: 10.1103/PhysRevD.53.6941
Abstract: We calculate the induced Einstein action from supersymmetric models in general space-time. Supersymmetric models consist of two kinds of supermultiplets, called scalar supermultiplets and vector supermultiplets, respectively. We show that the vector multiplets generate a negative Newton constant, while the scalar multiplets a positive one. Then we find that the positivity of Newton constant depends on the ratio of the number of scalar multiplets to one of vector multiplets. If we apply this result to two hopeful supersymmetric unified models: one is minimal SUSY standard model and another is minimal SUSY SU(5) GUT, we are led to the conclusion that we need more than or equal to three generations of quark and lepton multiplets to have a positive Newton constant, i.e., an attractive gravity.
Influence of Type of Prosthesis on Oral Environment and the Number of Missing Teeth in Elderly Persons
Junko Tanaka,Masahiro Tanaka
International Journal of Dentistry , 2010, DOI: 10.1155/2010/584134
Abstract: The purpose of this study was to investigate the relationship between the number of missing teeth (MT) and the statuses of oral environmental factors (the stimulated salivary flow rate, buffering capacity, and the counts of mutans streptococci, lactobacilli, and Candida) in the elderly. The subjects were 64 elderly subjects with fixed prostheses and 49 who wore removable partial dentures aged over 65 years. We used one-way ANOVA to test for overall differences of the number of MT among 5 oral environmental factors. The significant differences were observed in the lactobacilli counts for different number of MT. The number of MT increased with an increase in the lactobacilli counts with removable denture. In conclusion, for the patients wearing removable dentures, increasing number of MT was associated with an increase in the lactobacilli counts in saliva. For the patients with crowns and fixed partial dentures, the number of MT was not significantly affected by salivary mutans streptococci, lactobacilli, and Candida counts. 1. Introduction Caries activity test using saliva is believed to provide useful information for selecting the type of prosthesis. The oral environmental factors considered in the caries activity test include both host and microbial factors associated with caries. We investigated the differences between the statuses of the oral environment factors in elderly individuals with fixed and those with removable prostheses. The results of our study revealed that the amount of cariogenic bacteria in persons with fixed prostheses is different from that of elderly persons with removable dentures [1]. However, there is little evidence to design the prosthesis on the basis of the results of caries activity test. The population of the elderly has been increasing worldwide. There is an increase in the number of risk factors of oral diseases and MT in the elderly. The type of prosthesis was decided by the number of MT in most cases. However, the distal extension missing must place removable denture even if the number of MT is little. Therefore, the oral environment should examine not only the statue of the prosthesis, but also the number of missing teeth. To prevent an increase in the number of MT, maintenance of oral environmental factors is valuable and important. The purpose of this study was to investigate the relationship between the statuses of oral environmental factors and the number of MT in elderly persons with different types of prosthesis. 2. Material and Method This study protocol was screened and approved for its ethical acceptability
Chaotic inflation with running nonminimal coupling
Toshifumi Futamase,Masahiro Tanaka
Physics , 1997, DOI: 10.1103/PhysRevD.60.063511
Abstract: We have found a successful model of chaotic inflation with an inflaton coupled nonminimally with gravity. The nonminimal coupling constant $\xi$ runs with the evolution of the inflaton. The running nature of the coupling leads naturally to the situations where the coupling becomes small enough to have sufficient period of the inflation to resolve the cosmological puzzles.
Relationship between Cariogenic Bacteria and pH of Dental Plaque at Margin of Fixed Prostheses
Junko Tanaka,Norio Mukai,Muto Tanaka,Masahiro Tanaka
International Journal of Dentistry , 2012, DOI: 10.1155/2012/452108
Abstract: Objective. The purpose of this study was to investigate whether teeth that have undergone prosthetic restoration are under conditions that promote caries recurrence. Methods. The subjects were 20 dentate adults with both a healthy tooth and an affected tooth entirely covered with a complete cast crown in the molar regions of the same arch. The pH was measured in plaque adhering to the margin of the tooth covered with a complete cast crown and adhering to the cervicobuccal area of the natural tooth. In addition, the numbers of cariogenic bacteria (mutans streptococci and lactobacilli) were measured employing the saliva test. The relationships between the number of cariogenic bacteria and plaque pH of the natural tooth and between the number of cariogenic bacteria and plaque pH of the tooth covered with a complete cast crown were investigated. Results. The plaque pH of the tooth covered with a complete cast crown decreased as the numbers of SM and LB increased. The natural tooth were also influenced by the number of SM. Conclusion. Secondary caries are likely to develop from the marginal region of the crown in the oral cavity with a high caries risk unless a preventive program is prepared and the oral environment is improved following the program.
Metastatic Carcinoma of the Uterine Cervix from Rectal Carcinoma: A Case Report and Review of the Literature  [PDF]
Motoki Matsuura, Masato Tamate, Masahiro Suzuki, Tasuku Mariya, Sakura Takada, Yuta Tabuchi, Mizue Teramoto, Seiro Satohisa, Ryoichi Tanaka, Masahiro Iwasaki, Kaori Fukunaka, Noriyoshi Fukunaka, Satoshi Tanaka, Tsuyoshi Saito
Open Journal of Obstetrics and Gynecology (OJOG) , 2014, DOI: 10.4236/ojog.2014.410085

Primary adenocarcinomas of the uterine cervix account for 5% - 15% of all cervical malignancies, but secondary adenocarcinomas from extragenital cancers are rare. Only 35 cases have been reported in the literature since 1941. We report a 52-year-old Japanese woman who had been treated for rectal adenocarcinoma (Dukes C, stage IIIb) and who was diagnosed with primary uterine cervical carcinoma (FIGO stage Ib2) two years later. A radical hysterectomy was performed and the surgical specimen showed metastatic adenocarcinoma of the uterine cervix from rectal cancer without direct extension. Immunohistochemical staining was positive for cytokeratin 20 and CDX2, and negative for cytokeratin 7. Immunohistochemical staining is important for distinguishing between primary and secondary adenocarcinomas of the cervix, but histologic findings alone are not always adequate to establish the site of the primary lesion. The distinction between primary and secondary adenocarcinomas of the cervix is important for patient management and prognosis. Therefore, the possibility of metastatic adenocarcinoma should be considered whenever a diagnosis of adenocarcinoma of the cervix is received.

The Relation between Mixed Boundary States in Two- and Three- Matrix Models
Masahiro Anazawa,Atushi Ishikawa,Hirokazu Tanaka
Physics , 1997, DOI: 10.1143/PTP.98.457
Abstract: We discuss the relation among some disk amplitudes with non-trivial boundary conditions in two-dimensional quantum gravity. They are obtained by the two-matrix model as well as the three-matirx model for the case of the tricritical Ising model. We examine them for simple spin configurations, and find that a finite number of insertions of the different spin states cannot be observed in the continumm limit. We also find a closed set of eight Schwinger-Dyson equations which determines the disk amplitudes in the three-matrix model.
Interaction of boundaries with heterogeneous matter states in matrix models
Masahiro Anazawa,Atushi Ishikawa,Hirokazu Tanaka
Physics , 1997, DOI: 10.1016/S0550-3213(97)00791-8
Abstract: We study disk amplitudes whose boundary conditions on matter configurations are not restricted to homogeneous ones. They are examined in the two-matrix model as well as in the three-matrix model for the case of the tricritical Ising model. Comparing these amplitudes, we demonstrate relations between degrees of freedom of matter states in the two models. We also show that they have a simple geometrical interpretation in terms of interactions of the boundaries. It plays an important role that two parts of a boundary with different matter states stick each other. We also find two closed sets of Schwinger-Dyson equations which determine disk amplitudes in the three-matrix model.
Three Inverted Meckel’s Diverticula Cases with Ileus Diagnosed Preoperatively and Treated Laparoscopically  [PDF]
Kazuya Naritomi, Yuya Tanaka, Hiroki Ureshino, Yoshihiro Uchino, Motohisa Kuwahara, Yuhei Kitazato, Masahiro Kawabata, Masae Mano
Surgical Science (SS) , 2016, DOI: 10.4236/ss.2016.72009
Abstract: We have experienced three inverted Meckel’s diverticula with ileus that are diagnosed before surgery and treated with laparoscopic surgery. The patients were 22, 26, and 29 years of age. The history of ileus for each patient differed, being the first experience for one patient, the second for another, and the third experience for the remaining patient. None of these patients had a history of abdominal surgery. Conservative therapy eventually improved the existing symptoms, but the cause of past ileus remained unclear. Elective surgery was performed 12 days from the onset of symptoms on two of the patients after improving the ileus by inserting a long tube into the bowel. Emergency surgery was performed on the same day of admission on the remaining case that involved moderate expansion of intestine. In these patients, the first trocar was inserted into the umbilicus region. Laparoscopic surgery was then performed with three trocars. The patients were discharged upon favorable outcome after surgery. No recurrence of ileus was noted post-surgery. Laparoscopy was useful both to diagnose and treat ileus of a Meckel’s diverticulum.
Unique Properties of Hepatocarcinogenesis-Resistant DRH Rat Hepatocytes Linked or Not Linked to the Drh1 Locus on Rat Chromosome 1
Norikazu Hashimoto,Masahiro Yamamoto,Masaaki Miyakoshi,Hiroki Tanaka,Katsuhiro Ogawa
International Journal of Hepatology , 2011, DOI: 10.4061/2011/424356
Abstract: Hepatocarcinogenesis-resistant DRH rats exhibit few and small preneoplastic hepatocytic lesions during hepatocarcinogenesis, of which traits have been assigned to two major chromosomal regions, Drh1 and Drh2. In this study, hepatocytes from DRH.F344-Drh1, a congenic strain in which the Drh1 chromosomal region was replaced with that of F344 rats, were compared to hepatocytes from Donryu (original strain), DRH, and F344 rats. Although DRH hepatocytes exhibited low proliferation and p38 dephosphorylation after lead nitrate (LN) treatment despite cytokine and Cox2 activation, DRH.F344-Drh1 hepatocytes exhibited high responses, as did Donryu and F344 hepatocytes. Moreover, although DRH hepatocytes were resistant to hepatotoxins, DRH.F344-Drh1 hepatocytes were as sensitive to hepatotoxins as Donryu and F344 hepatocytes. However, DRH.F344-Drh1 hepatocytes like DRH hepatocytes proliferated at lower rates in vitro and contained smaller nuclei than Donryu and F344 hepatocytes. Thus, low responses to LN and resistance to hepatotoxins in DRH hepatocytes were linked to the Drh1 locus, while low proliferation in vitro and small nuclear size were not linked to the Drh1 locus.
Skin Barrier Homeostasis in Atopic Dermatitis: Feedback Regulation of Kallikrein Activity
Reiko J. Tanaka,Masahiro Ono,Heather A. Harrington
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0019895
Abstract: Atopic dermatitis (AD) is a widely spread cutaneous chronic disease characterised by sensitive reactions (eg. eczema) to normally innocuous elements. Although relatively little is understood about its underlying mechanisms due to its complexity, skin barrier dysfunction has been recognised as a key factor in the development of AD. Skin barrier homeostasis requires tight control of the activity of proteases, called kallikreins (KLKs), whose activity is regulated by a complex network of protein interactions that remains poorly understood despite its pathological importance. Characteristic symptoms of AD include the outbreak of inflammation triggered by external (eg. mechanical and chemical) stimulus and the persistence and aggravation of inflammation even if the initial stimulus disappears. These characteristic symptoms, together with some experimental data, suggest the presence of positive feedback regulation for KLK activity by inflammatory signals. We developed simple mathematical models for the KLK activation system to study the effects of feedback loops and carried out bifurcation analysis to investigate the model behaviours corresponding to inflammation caused by external stimulus. The model analysis confirmed that the hypothesised core model mechanisms capture the essence of inflammation outbreak by a defective skin barrier. Our models predicted the outbreaks of inflammation at weaker stimulus and its longer persistence in AD patients compared to healthy control. We also proposed a novel quantitative indicator for inflammation level by applying principal component analysis to microarray data. The model analysis reproduced qualitative AD characteristics revealed by this indicator. Our results strongly implicate the presence and importance of feedback mechanisms in KLK activity regulation. We further proposed future experiments that may provide informative data to enhance the system-level understanding on the regulatory mechanisms of skin barrier in AD and healthy individuals.
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