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Search Results: 1 - 10 of 205702 matches for " Mary P. Metcalf "
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Assessment of an Interactive Internet Program to Educate Children Aged 7 - 9 about Science, the Brain and Drugs  [PDF]
Mary P. Metcalf
Creative Education (CE) , 2013, DOI: 10.4236/ce.2013.411097
Abstract: BrainTrain4Kids.com is an interactive science Internet program for children aged 7 - 9 developed with funding from the National Institute on Drug Abuse (NIDA). Based on NIDA’s classroom curriculum, Brain Power!, we adapted and expanded this material to optimize online media. The primary objective of the curriculum is to provide an early foundation for drug abuse prevention efforts by educating elementary school-aged children about the brain and how alcohol, tobacco, and drugs can harm it. Secondary aims include improving knowledge, appreciation for scientific inquiry, and improving/sustaining a positive attitude towards science. The program employs engaging and entertaining elements including Flashbased activities and educational games. Assessment of the program occurred using a two-group, randomized case/control pre/post trial with a crossover design using a convenience sample. Child participants (N = 102) from control and case groups had similar knowledge and attitudes towards science at baseline. At post-intervention, there was a significant increase in knowledge scores for the case group; this increase was retained at the six-week follow-up. Case group attitudes towards science were more positive immediately after post-intervention than at baseline, and at follow up than at baseline. BrainTrain4Kids can be an effective tool for educating children about science and drugs, and has the potential to positively impact attitudes. It can be used as a part of a drug abuse prevention program either in schools or at home.
Effectiveness of an online curriculum for medical students on genetics, genetic testing and counseling
Mary P. Metcalf,T. Bradley Tanner,Amanda Buchanan
Medical Education Online , 2010, DOI: 10.3402/meo.v15i0.4856
Abstract: Background: It is increasingly important that physicians have a thorough understanding of the basic science of human genetics and the ethical, legal and social implications (ELSI) associated with genetic testing and counseling. Methods: The authors developed a series of web-based courses for medical students on these topics. The course modules are interactive, emphasize clinical case studies, and can easily be incorporated into existing medical school curricula. Results: Results of a ‘real world’ effectiveness trial indicate that the courses have a statistically significant effect on knowledge, attitude, intended behavior and self-efficacy related to genetic testing (p<0.001; N varies between 163 and 596 for each course). Conclusions: The results indicate that this curriculum is an effective tool for educating medical students on the ELSI associated with genetic testing and for promoting positive changes in students' confidence, counseling attitudes and behaviors.
Notes and Descriptions of the Cercopidze of Cuba
Z. P. Metcalf,S. C. Bruner
Psyche , 1925, DOI: 10.1155/1925/36181
Notes on Aphrophora Salicis De Geerin America
Z. P. Metcalf,G. W. Barber
Psyche , 1929, DOI: 10.1155/1929/45257
Cuban Fulgorina. 1. The Families Tropiduchidae and Acanaloniidae
Z. P. Metcalf,S. C. Bruner
Psyche , 1930, DOI: 10.1155/1930/86504
Improved Dynamic Response of DC to DC Converter Using Hybrid PSO Tuned Fuzzy Sliding Mode Controller  [PDF]
R. Anand, P. Melba Mary
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.76080
Abstract: DC/DC switching converters are widely used in numerous appliances in modern existence. In this paper, the dynamic and transient response of phase shift series resonant DC/DC converter are improved using hybrid particle swarm optimization tuned fuzzy sliding mode controller under starting and load step change conditions. The aim of the control is to regulate the output voltage beneath the load change. The model of the hybrid particle swarm optimization tuned fuzzy sliding mode controller is implemented using Sim Power Systems toolbox of MATLAB SIMULINK. Performance of the proposed dynamic novel control under step load change condition is investigated.
Design of Robust Controller for LFC of Interconnected Power System Considering Communication Delays  [PDF]
T. Jesintha Mary, P. Rangarajan
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.76068
Abstract: The usage of open communication infrastructure for transmitting the control signals in the Load Frequency Control (LFC) scheme of power system introduces time delays. These time delays may degrade the dynamic performance of the power system. This paper proposes a robust method to design a controller for multi-area LFC schemes considering communication delays. In existing literature, the controller values of LFC are designed using time domain approach which is less accurate than the proposed method. In proposed method, the controller values are determined by moving the rightmosteigenvalues of the system to the left half plane in a quasi-continuous way for a preset upper bound of time delay. Then the robustness of the proposed controller is assessed by estimating the maximumtolerable value of time delay for maintaining system stability. Simulation studies are carried out for multi-area LFC scheme equipped with the proposed controller
An Improved Hybrid Space Vector PWM Technique for IM Drives  [PDF]
P. Muthukumar, P. Melba Mary, S. Jeevananthan
Circuits and Systems (CS) , 2016, DOI: 10.4236/cs.2016.79184
Abstract: In this paper, an improved hybrid space vector pulse width modulation (HSVPWM) technique is proposed for IM (induction motor) drives. The basic principle involved in the proposed random pulse width modulation (RPWM) cuddled SVPWM is amalgamating the pre-calculated switching timings for various sections of hexagonal space vector boundary and the random selection of carrier between two triangular signals, in order to disband acoustic switching noise spectrum with improved fundamental component. The arbitrary selection between triangular carriers, which is decided by digital signal states (Low or High) of the linear feedback shift register (LFSR) based pseudo random binary sequence (PRBS) generator. The SVPWM offers a control degree of freedom in terms of positioning of vectors inside every sampling interval and hence it has six possible variants of the voltage vectors arrangements in each sector. The developed HSVPWM is thoroughly analyzed in using the MATLAB? based simulation for all SVPWM variants. From the simulation and experimental results viz. harmonic spectrum, harmonic spread factor (HSF), total harmonic distortion (THD) etc., and the superiority of the proposed scheme such as better utilization of DC bus and the randomization of the harmonic power are evidenced. For the practical implementation, Xilinx XC3S500E FPGA device has been used.
Lattice softening effects at the Mott critical point of Cr-doped V$_2$O$_3$
S. Populoh,P. Wzietek,R. Gohier,P. Metcalf
Physics , 2010, DOI: 10.1103/PhysRevB.84.075158
Abstract: We have performed sound velocity measurements in (V$_{1-x}$Cr$_x$)$_2$O$_3$ in the vicinity of the critical point of the first order Mott transition line. The pressure sweeps at constant temperature reveal a large dip in the $c_{33}$ compression modulus, this dip sharpens as the critical point is approached. We do not observe signs of criticality on the shear modulus $c_{44}$ which is consistent with a transition governed by a scalar order parameter, in accordance with the DMFT description of the transition. However, the amplitude of the effect is an order of magnitude smaller than the one obtained from DMFT calculations for a single band Hubbard model. We analyze our results using a simple model with the electronic response function obtained from the scaling relations for the conductivity.
Influenza A(H1N1)pdm09 Virus Suppresses RIG-I Initiated Innate Antiviral Responses in the Human Lung
Wenxin Wu, Wei Zhang, J. Leland Booth, Jordan P. Metcalf
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0049856
Abstract: Influenza infection is a major cause of morbidity and mortality. Retinoic acid-inducible gene I (RIG-I) is believed to play an important role in the recognition of, and response to, influenza virus and other RNA viruses. Our study focuses on the hypothesis that pandemic H1N1/09 influenza virus alters the influenza-induced proinflammatory response and suppresses host antiviral activity. We first compared the innate response to a clinical isolate of influenza A(H1N1)pdm09 virus, OK/09, a clinical isolate of seasonal H3N2 virus, OK/06, and to a laboratory adapted seasonal H1N1 virus, PR8, using a unique human lung organ culture model. Exposure of human lung tissue to either pandemic or seasonal influenza virus resulted in infection and replication in alveolar epithelial cells. Pandemic virus induces a diminished RIG-I mRNA and antiviral cytokine response than seasonal virus in human lung. The suppression of antiviral response and RIG-I mRNA expression was confirmed at the protein level by ELISA and western blot. We performed a time course of RIG-I and interferon-β (IFN-β) mRNA induction by the two viruses. RIG-I and IFN-β induction by OK/09 was of lower amplitude and shorter duration than that caused by PR8. In contrast, the pandemic virus OK/09 caused similar induction of proinflammatory cytokines, IL-8 and IL-6, at both the transcriptional and translational level as PR8 in human lung. Differential antiviral responses did not appear to be due to a difference in cellular infectivity as immunohistochemistry showed that both viruses infected alveolar macrophages and epithelial cells. These findings show that influenza A(H1N1)pdm09 virus suppresses anti-viral immune responses in infected human lung through inhibition of viral-mediated induction of the pattern recognition receptor, RIG-I, though proinflammatory cytokine induction was unaltered. This immunosuppression of the host antiviral response by pandemic virus may have contributed to the more serious lung infections that occurred in the H1N1 pandemic of 2009.
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