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Search Results: 1 - 10 of 7012 matches for " Mary Jerome Obiorah "
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Prayer for Good Governance: A Study of Psalm 72 in the Nigeria Context  [PDF]
Mary Jerome Obiorah
Open Journal of Philosophy (OJPP) , 2013, DOI: 10.4236/ojpp.2013.31A032

Contextualizationof Biblical texts is a priority of every exegete, who endeavors to bring the ancient scripts to dialogue with contemporary issues. This paper, which studies Psalm 72 and a prayer composed for good governance in Anambra State Nigeria, focuses on this hermeneutical interpretation. The writer adopts a simplified literary method in Biblical research that takes cognizance of the varied poetic techniques in Psalm 72 and engages in a detailed comparative study of a Psalm composed more than two millennia ago and a prayer of our time. Such comparative study reveals a striking similar preoccupation of the composers of both texts. Both prayed for good governance of which all developing countries today are in dire need.

“Do Not Weep” (Luke 7: 13): In the Footstep of the Compassionate Jesus  [PDF]
Mary Jerome Obiorah
Open Journal of Philosophy (OJPP) , 2014, DOI: 10.4236/ojpp.2014.43028

The divine image, which every human being bears as a result of God’s benevolence at creation, attracts us to the Divine. Human beings are religious by nature and in order to fully realise themselves as humans they have to be and live out the divine qualities instilled in each of them by the Creator. The opposite is often the case when human actions are critically evaluated. One of the divine qualities, which we ought to acquire and practice in order to enhance good human relationship, is compassion. This singular divine feature characterised Jesus earthly ministry in words and deeds. In this paper, the writer focuses on an episode in the life of Jesus, as recorded in the Gospel according to Luke 7: 11-17. Jesus had compassion on the widow who lost her only son; he consoled and restored her son back to her. In following Jesus’ footsteps we can make our world better and be able to bear and live with others.

“Like Olive Shoots”: Insight into the Secret of a Happy Family in Psalm 128  [PDF]
Mary Jerome Obiorah
Open Journal of Philosophy (OJPP) , 2015, DOI: 10.4236/ojpp.2015.51008
Abstract: Beset by all kinds of ideologies that divest it of its divinely endowed values, family in our contemporary society suffers greatly from those who purport to have a better way of fulfilling its divine mandate. All who understand the importance of family are greatly concerned at the overt derailment that has proved detrimental to human society. The Sacred Scripture offers us varied insights into solving the problem in which we find ourselves. Psalm 128 chosen for this paper is one of those texts in the Bible that reflects on family and its value in human society. As a Wisdom Psalm and didactic in nature, the poem presents to its readers what family is in dire need of at this time. The meaning of this Psalm is coded in its rich poetic techniques and similes that the paper endeavours to explain in its immediate context as a Song of Ascents and in the contexts of other Wisdom texts of the Old Testament. Its theological thrust, the fear of God, which is introduced at the beginning and iterated in various phrases within the Psalm comes out clearly as messages the Psalm offers to worrisomely deformed image of family in our time.
Evaluation and Management of Massive Endotracheal Hemorrhage in Pediatric Patients: A Case Report and Review of Literature  [PDF]
Cory Vaughn, Mona Shete, Rose Mary Stocks, Jerome Thompson
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2013, DOI: 10.4236/ijohns.2013.26049

Massive hemoptysis is a frightening and life-threatening event in children. Prompt, aggressive evaluation and management are necessary. The most common cause of hemoptysis in a pediatric patient is infectious, but other various etiologies including tracheotomy related problems, cystic fibrosis, bronchiectasis, congenital anomalies of the cardiopulmonary vasculature and suction trauma must be considered as well. Presented is a report of a case of acute, massive endotracheal hemorrhage with multiple methods of management including balloon tamponade, highly selective embolization, and mainstem occlusion. This case is an addition to our previously reported case series of nine pediatric patients with massive pulmonary hemorrhage. Various diagnostic and management techniques of hemoptyis in pediatric patients are discussed with an extensive review of the literature.

The Role of Dutasteride in Acute Prostatic Haematuria  [PDF]
Vitalis Obisike Ofuru, Christopher Chinedu Obiorah
International Journal of Clinical Medicine (IJCM) , 2017, DOI: 10.4236/ijcm.2017.811056
Abstract: Background: Dutasteride has been found to reduce chronic prostatic bleeding and when taken 2 - 6 weeks preoperatively reduces bleeding during transurethral prostate resection. The aim of this study is to determine if the drug will be effective in the control of acute gross prostatic haematuria. Patients and Method: 87 Consecutive patients with gross haematuria were enrolled. Clotting Profile, Cystoscopy and Intravenous Urography were done to exclude haematuria from medical, renal and bladder causes. Patients suspected to have prostatic haematuria were further evaluated using serum Prostate specific antigen (PSA) and Prostate scan. Those with elevated PSA ≥ 10 ng/ml and abnormal digital rectal examination (DRE) finding had prostate biopsy. The patients were randomly divided into 2 treatment groups. The control group had Normal saline irrigation and broad spectrum antibiotics while the second group received 0.5 mg oral dutasteride in addition. The time taken and volume of irrigation fluid used before haematuria stopped were noted. Statistical analysis was done using SPSS version 20.0. Result: 75 patients had haematuria of prostatic origin. 49 (65.3%) of these had benign prostatic hyperplasia (BPH) and 26 (34.7%) had cancer of prostate. 25(51%) of the 49 patients with BPH had Normal saline irrigation and antibiotics while 24 (49%) had oral dutasteride in addition. 14 (53.8%) of the prostate cancer patients had Normal saline irrigation and antibiotics while 12 (46.2%) had dutasteride in addition. Haematuria resolved in significantly shorter length of time using lesser volume of irrigation fluid in those treated with dutasteride than in those on control arm. Conclusion: Addition of 0.5 mg oral dutasteride daily leads to early resolution of acute prostatic haematuria.
Pre-Androgen Ablation Prostate Cancer Patients Who Bleed Do Well with 5 Alpha Reductase Inhibitors  [PDF]
Vitalis Obisike Ofuru, Christopher Chinedu Obiorah
Open Journal of Urology (OJU) , 2018, DOI: 10.4236/oju.2018.86020
Abstract: Background: Patients with gross haematuria are sometimes found to have prostate cancer after clinical evaluation. The treatment of such haematuria could be very challenging. Use of a 5 alpha reductase inhibitor like dutasteride has been found helpful in bleeding prostate cancer patients if they have not undergone hormonal manipulation before they developed haematuria. Patients and Method: 26 patients with gross haematuria of prostatic origin who had histologic confirmation of adenocarcinoma of the prostate but who have not had chemical or surgical castration were randomized to receive daily dutasteride in addition to vigorous saline irrigation and antibiotics on one arm and vigorous saline irrigation and antibiotics only as control on the other arm. The time taken before haematuria resolved and the amount of irrigation fluid used were noted. Statistical analysis was done using SPSS. Student’s t-test and Kaplan Meier survival analysis were used to test various variables at 0.5 significant levels. Results: Of the 26 patients 12(46.2%) received 0.5 mg oral dutasteride in addition to saline irrigation while 14 (53.8%) received saline irrigation only. Haematuria stopped in all of 12 (100%) patients on dutasteride arm but on 12 (85.7%) of the 14 patients on the control arm. It took significantly shorter time and lesser volume of irrigation fluid before haematuria resolved in those treated with dutasteride than in those on the control arm. Conclusion: Dutasteride is effective in the control of acute haematuria in pre-androgen ablation prostate cancer patients.
A histopathological study of carcinoma of the prostate in port Harcourt, Nigeria
CC Obiorah, SO Nwosu
Nigerian Journal of Clinical Practice , 2011,
Abstract: Objectives: To determine the incidence of prostate cancer in Port Harcourt and the surrounding towns whose residents patronize the University of Port Harcourt Teaching Hospital for tertiary health care, histologically characterize the patterns of these cancers, and grade them according to the Gleason scheme. Materials and Methods: Blocks and slides of prostate specimens received at the Department of Anatomical Pathology, University of Port Harcourt Teaching Hospital between January 1997 and December 2006 were retrospectively selected for this study. The slides were studied using a binocular Olympus light microscope. Patients’ age at presentation, presenting symptoms, and clinical diagnosis were sorted out from the request cards and the department’s archival register. Results: Carcinoma was diagnosed in 198 specimens (37.4%) of the 529 cases reviewed. Of these, 164 (82.8%) were clinical carcinoma (having been found in clinically suspected carcinoma cases for which trucut biopsies were undertaken), while 34 (17.2%) were incidental carcinoma cases (being found in prostatectomy biopsy cases of patients clinically diagnosed with nodular hyperplasia). All of the clinical carcinomas were adenocarcinomas predominantly moderately differentiated and of large acinar pattern. Also, all of the incidental carcinomas were adenocarcinomas predominantly well differentiated and of large acinar pattern. The Gleason scores (GSs) were varied but predominantly of high values, particularly with clinical carcinoma cases. The age range was 42 to 90 years and the mean was 70 years with a peak of 70 to 79 years. Conclusion: The incidence of prostate cancer in Port Harcourt is high relative to other Nigerian centers where similar studies have been carried out and compares well with the high incidence found among African American men. Histologically, all cases are acinar adenocarcinomas. Most patients present late with high GS carcinoma and therefore have poor prognosis. There is a need for enlightenment of the male populace on the high incidence of this deadly disease as well as for screening to reduce the number of patients presenting late and therefore improve prognosis.
Systemic Analysis of Sudden Natural Deaths at Braithwaite Memorial Specialist Hospital Port Harcourt, Nigeria
CC Obiorah, CNT Amakiri
Nigerian Health Journal , 2012,
Abstract: Background: Many cases of sudden unexpected natural deaths occur in individuals without known medical diseases. Relatives of such victims and the law enforcement agents often designate those as sudden and unnatural deaths (SUD), and call for coroners inquests. Aims: To analyze the anatomic causes of sudden natural deaths investigated by the Coroner at Braithwaite Memorial Specialist Hospital (BMSH), and to classify them according to body systems and compare our findings with those of previous studies. Materials and methods: This is a nine-year retrospective study carried out in BMSH Port Harcourt, Nigeria. The reports of unlimited and standardized autopsies carried out on sudden and natural death victims were retrieved and analyzed. The causes of death were grouped according to the body systems involved. The cases were also analyzed according to age, sex, and circumstances of death. Results: Of the 9,164 bodies received, 2,415 (26.4%) were autopsied for varied reasons, out of which 249 (2.7%) were sudden natural deaths in persons without known significant medical history. Male: female ratio (MFR) was 2.2:1. The mean age was 39.7 years with a range of 3 weeks to 97 years. Peak age group was 30-39 years with 27.7%. Cardiovascular system pathologies were by far the commonest causes of death with 87.6%. The least cause of death was prematurity with 0.4%. Among the cardiovascular system pathologies, hypertensive heart disease was the commonest. All deathswere from natural causes. Conclusion: Cardiovascular system pathologies especially hypertensive heart disease remain the leading cause of sudden natural deaths in this study. Residents of Rivers state of Nigeria should be more conscious of their health and undergo regular medical check-ups for early detection and proper management of cardiovascular diseases especially systemic hypertension. Key Words: Sudden natural deaths, autopsy, coroner, hypertension, Port Harcourt.
Model for Assessment Evaluation of Methane Gas Yield Based on Hydraulic Retention Time during Fruit Wastes Biodigestion  [PDF]
Chukwuka Nwoye, Asuke Ferdinand, Ijomah Agatha, Obiorah Samuelmary
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2012, DOI: 10.4236/jmmce.2012.1110093
Abstract: This paper presents an assessment evaluation of methane gas yield using a derived model based on the hydraulic retention time (HRT) of the feed stock (waste fruits) undergoing biotreatment in the digester. The derived model; γ = e(3.5436 α + 2.0259) indicates an exponential relationship between methane yield and the HRT. Statistical analysis of the model-predicted and experimental gas methane yield for each value of HRT considered shows a standard error of 0.0081 and 0.0114% respectively. Furthermore, the correlation between methane yield and HRT as obtained from derived model and experimental results were evaluated as 0.9716 and 0.9709 respectively. Methane gas yield per unit HRT as obtained from derived model and experiment are 0.0196 and 0.0235 (m3kg-1 VS) days-1 respectively. Deviational analysis indicates that the maximum deviation of the model-predicted methane yield from the corresponding experimental value is less than 16%. It was also found that the validity of the model is rooted on the expression 0.2822 ln γ = α + 0.5717 where both sides of the expression are correspondingly approximately equal.
Tobacco, alcohol, and p53 overexpression in early colorectal neoplasia
Mary Terry, Alfred I Neugut, Mahesh Mansukhani, Jerome Waye, Noam Harpaz, Hanina Hibshoosh
BMC Cancer , 2003, DOI: 10.1186/1471-2407-3-29
Abstract: We examined p53 status, as measured by protein overexpression, in 157 cases with early colorectal neoplasia selected from three New York City colonoscopy clinics. After collecting paraffin-embedded tissue blocks, immunohistochemistry was performed using an anti-p53 monoclonal mouse IgG2a [BP53-12-1] antibody. We analyzed whether p53 status was different for risk factors for colorectal neoplasia relative to a polyp-free control group (n = 508).p53 overexpression was found in 10.3%, 21.7%, and 34.9%, of adenomatous polyps, CIS, and intramucosal cases, respectively. Over 90% of the tumors with p53 overexpression were located in the distal colon and rectum. Heavy cigarette smoking (30+ years) was associated with cases not overexpressing p53 (OR = 1.8, 95% CI = 1.1–2.9) but not with those cases overexpressing p53 (OR = 1.0, 95% CI = 0.4–2.6). Heavy beer consumption (8+ bottles per week) was associated with cases overexpressing p53 (OR = 4.0, 95% CI = 1.3–12.0) but not with cases without p53 overexpression (OR = 1.6, 95% CI = 0.7–3.7).Our findings that p53 overexpression in early colorectal neoplasia may be positively associated with alcohol intake and inversely associated with cigarette smoking are consistent with those of several studies of p53 expression and invasive cancer, and suggest that there may be relationships of smoking and alcohol with p53 early in the adenoma to carcinoma sequence.The molecular model of genetic changes along the colorectal adenoma-carcinoma sequence, first described by Vogelstein and colleagues, has become the framework for understanding the timing and role multiple mutations and genetic alterations play in carcinogenesis [1]. It is thought that multiple mutations are needed for invasive cancer [1-4]. Although the number of mutations and not their order has been found to be paramount, there are general trends in terms of timing in the sequence. Of more common genes important to colorectal carcinogenesis (e.g., APC, K-ras, and p53), most data
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