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Search Results: 1 - 10 of 329669 matches for " Mary Jelastin Kala S "
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Antioxidant, Antihyperlipidaemic and Antidiabetic Activity of Eugenia Floccosa Bedd Leaves in Alloxan Induced Diabetic Rats
Mary Jelastin Kala S,Tresina P.S.,Mohan V.R.2
Journal of Basic and Clinical Pharmacy , 2012,
Abstract: The ethanol extract of Eugenia floccosa Bedd (Family: Myrtaceae) leaf was investigated for its antioxidant, antihyperlipidaemicand antidiabetic effect in Wistar Albino rats. Diabetes was induced in Albino rats by administration of alloxan monohydrate (150mg/kg, i.p). The ethanol extracts of E. floccosa at a dose of 150 and 300mg/kg of body weight were administered at single dose per day to diabetes induced rats for a period of 14 days. The effect of ethanol extract of E. floccosa leaf extract on blood glucose, plasma insulin, creatinine, glycosylated haemoglobin, urea serum lipid profile [total cholesterol (TR), triglycerides (TG), low density lipoprotein – cholesterol (LDL-C), very low density lipoprotein– cholesterol (VLDL-C), high density lipoprotein – cholesterol (HDL-C) and phospholipid (PL)] serum protein, albumin,globulin, serum enzymes [serum glutamate pyruvate transaminases (SGPT) and serum glutamate oxaloacetate transaminases(SGOT), and alkaline phosphatase (ALP)], lipoprotein peroxidation (LPO) antioxidant enzymes (catalase (CAT),superoxide dismutase (SOD), reduced glutathione (GSH) and glutathione peroxidase (GPx) were measured in the diabetic rats. The ethanol extract of Eugenia floccosa leaf elicited significant reductions of blood glucose (P<0.05), lipid parameters except HDL-C, serum enzymes and significantly increased HDL-C and antioxidant enzymes. The extracts also caused significant increase in plasma insulin (P<0.05) in the diabetic rats. From the above results, it is concluded that ethanol extract of Eugenia floccosa possesses significant antidiabetic, antihyperlipidaemic and antioxidant effectsin alloxan induced diabetic rats.
HPTLC FINGER PRINT ANALYSIS OF PHYTOCOMPOUNDS AND IN VITRO ANTIOXIDANT ACTIVITY OF EUGENIA FLOCCOSA BEDD.
Tresina, P.S.,Mary Jelastin Kala, S,Mohan V.R.
Bioscience Discovery , 2012,
Abstract: This paper has reported the preliminary phytochemical screening, HPTLC analysis of phytocompounds and in vitro antioxidant activities of ethanol extract of Eugenia floccosa leaves. This is the first report on the antioxidant activity of this plant. The preliminary phytochemical analysis showed the presence of alkaloids, coumarin, catechin, steroids, flavonoids, saponins, phenols, glycosides and terpenoids. HPTLC analysis also confirmed the presence of alkaloids, steroids, flavonoids, saponins, phenols, glycosides and terpenoids. The antioxidant activities of the leaves in ethanol extract are assessed using different models like DPPH, superoxide radical, hydroxyl radical and ABTS+ cation radical and reducing power at different concentrations. The ethanol extract at 800μg/ml showed maximum scavenging activity. Results obtained revealed that, ethanol extract of leaves of E. floccosa possess highly antioxidant activity. Thus his study suggests that, E. floccosa plant can be used as a potent source of natural antioxidant.
Antimicrobial Activity of Acanthephippium bicolor, Lindley
Kala, S.,Senthilkumar, S.
Malaysian Journal of Microbiology , 2010,
Abstract: The Kolli hills, a part of Eastern Ghats of India is a treasure of medicinal plants. An attempt is made to gather information about the traditional use of herbs from the local healers. Acanthephippium bicolor Lindley is being used to treat urinary tract infection. Different parts (leaf, bulb and root) are collected in two seasons (summer and winter) and phytochemicals present in them are analyzed. Leaf is found to possess most of the phytochemicals. Hence leaf is selected as study material. Antimicrobial activity of the various solvent extracts (methanol, ethanol, chloroform, acetone, ethyl acetate, benzene and hexane) is screened for both summer and winter samples. Of the 35 organisms studied, Staphylococcus aureus, Streptococcus foecalis, Bacillus cereus, Proteus vulgaris, Proteus mirabilis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Shigella dysenteriae, Escherichia coli, Microsporum audouinii, Microsporum fulvum, Candida albicans and Trichophyton rubrum are found to be sensitive to leaf extracts. The Gram-positive bacteria are found to be more sensitive than Gram-negative bacteria and fungi. The inhibition is found to be more in methanol extract. This proves that the bioactive compounds reside in methanolic extract. When the summer and winter samples are compared for their antimicrobial efficacy, there is no significant difference. This proves that there is no impact of season on antimicrobial activity of this plant. This research proves that Acanthephippium bicolor Lindley would be the best herbal medicine for Urinary Tract Infection and leaves can be used as herbal and scientific medicine throughout the year as there is no seasonal impact.
An analysis of discrete-continuous mechanical systems with conjugations
A. Skala
Journal of Achievements in Materials and Manufacturing Engineering , 2011,
Abstract: Purpose: The main purpose of this work is developing a methodology, using non-classical methods, of modelling the complex mechanical systems with the continuous and discrete-continuous distribution of parameters. A simple task of dynamics can be solved by using this method, without limitations deriving from the type and number of the elements of a mechanical system.Design/methodology/approach: By using the non-classical methods of modelling, it was possible to develop a method of determining the matrices (flexibilities) of multi-link vibration mechanical systems with the continuous distribution of parameters that are able to perform longitudinal and flexural vibrations. The method is focused on broadening graphs method by mechanical systems and improving their description and design methods so that the mathematical formalism can reflect the essence of the problem involved in the designation of dynamic characteristics of such systems.Findings: The knowledge of the dynamic characteristics of a system determined for any inputs and outputs in form of kinematic and dynamic excitations is underlying the determination of frequency characteristics of the class of the systems under consideration.Research limitations/implications: The class of the systems considered refers to investigating into the dynamic and vibration characteristics of mechanical systems with the discrete-continuous distribution of parameters performing small vibrations around the adopted state of equilibrium.Practical implications: The presented method of this study is that the main point can be the introduction to e.g. additional kinematic excitations in form of a function of speed and accelerations or extending the method presented to cover the investigation of non-linear systems.Originality/value: The modelling and analysis of discrete–continuous vibration systems with conjugations using the non-classical method is a more general approach as compared to modelling and analysis in classical terms.`
An innovative system for interactive rehabilitation of children at the age of three
I. Chuchnowska,A. Skala
Archives of Materials Science and Engineering , 2011,
Abstract: Purpose: The article discusses the assumptions and a concept of a system aiding progress in rehabilitation by stimulating a child’s senses through image and sound. A special rehabilitation device comprised of a training bike with a chair and a synoptic screen enables the patient to perform prophylactic and corrective exercises. Brain activity measurement with an EEG sensor is used as a function steering the rehabilitation process.Design/methodology/approach: The article discusses a method of combining traditional cyclotherapy with the stimulation of a child’s intellectual development with the Glenn Doman rehabilitation method or with music therapy depending on the degree of a child’s intellectual development.Findings: Combination of the traditional cycle-therapy with music therapy or Glenn Doman’s method in rehabilitation of small patients will help to maximize the children’s activity and their involvement, which at this stage of development is possible only by giving rehabilitation exercises an attractive form of plays and games.Research limitations/implications: In further stages of works it is expected to make a prototype device that can be transferred to a public benefit organization in order to conduct researches within their own works.Practical implications: The proposed device should be very effective in the rehabilitation process, even for the youngest children, and due to its relatively simple modular construction and the possibility of cooperation with many plays and games.Originality/value: The device being developed will include all the most important factors that may affect the physical structure of children and their psyche, which can directly affect the improvement of their health.
Application of interactive rehabilitation equipment for kinesitherapy of children with lower limbs dysfunction
I. Chuchnowska,A. Skala
Journal of Achievements in Materials and Manufacturing Engineering , 2012,
Abstract: Purpose: This article presents an innovative approach to the process of rehabilitation of children under 3 years of age. It shows a system supporting the process of rehabilitation based on cyclotherapy. This work presents a method of combining traditional cyclotherapy with stimulation of intellectual development of the child by means of using the Glenn Doman method or music therapy depending on the degree of intellectual development of the child. Rehabilitation will take place in the form of a play with the use of specially designed equipment.Design/methodology/approach: This work reviews selected methods of improving the children’s condition, which methods may be applied in interactive rehabilitation.Findings: The combination of movement-based therapy with mental stimulation will make it possible to use the child’s potential in a more effective way and quicken the process of rehabilitation.Research limitations/implications: In further stages of works it is expected to make a prototype device that can be transferred to a public benefit organization or an organization of a similar nature in order to conduct researches within their own works.Practical implications: The combination of movement therapy with psychological stimulation will exploit, to the maximum extent, natural abilities of brain development in small children. This is enormously important as it is often a factor that conditions the length and, first of all, the quality of life of the patients.Originality/value: The device being developed will include all the most important factors that may affect the physical structure of children and their psyche, which can directly affect the improvement of their health.
The concept of interactive rehabilitation device for children under the age of three
I. Chuchnowska,A. Skala
Journal of Achievements in Materials and Manufacturing Engineering , 2011,
Abstract: Purpose: This article presents the concept of an interactive rehabilitation equipment designed for children under 3 years of age with dysfunction of the lower limbs. Through the use of interactive play-boards and games not only will the children learn faster, but the whole process of rehabilitation will be really fun. Furthermore, the device can be connected to a computer or a special synoptic screen mounted on a special rack. Thanks to an interactive combination of the function of movement rehabilitation with mental stimulation of a child it will be possible to support the development of cognitive functions, cause-effect thinking, stimulation of the senses and to improve coordination and spatial orientation of the young patient.Design/methodology/approach: The novelty of the station is combination of the traditional cycle-therapy with the Glenn Doman improvement method, or with music therapy, depending on the degree of disability of a child. Findings: Combination of the traditional cycle-therapy with music therapy or Glenn Doman’s method in rehabilitation of small patients will help to maximize the children’s activity and their involvement, which at this stage of development is possible only by giving rehabilitation exercises an attractive form of plays and games.Research limitations/implications: FMEA is a very important method which should be employed in companies fPractical implications: The researches from the broadly understood biomechanics that are carried out shall lead to a construction of a rehabilitation device designed for children under the age of three. The proposed device should be very effective in the rehabilitation process, even for the youngest children, and due to its relatively simple modular construction and the possibility of cooperation with many plays and games, it should also be a market success by contributing to the effective rehabilitation of the considerable population of children who require such rehabilitation.Originality/value: The device being developed will include all the most important factors that may affect the physical structure of children and their psyche, which can directly affect the improvement of their health
Tuberculosis Verrucosa Cutis Developing over a Keloid: A Rare Presentation
S Kala, Ch Pantola, A Agarwal
Journal of Surgical Technique and Case Report , 2010,
Abstract: Cutaneous tuberculosis can present as either primary or secondary infection, or it can be associated with systemic tuberculosis. It can present with unusual clinical and histological features causing delay in diagnosis and treatment. Tuberculosis verrucosa cutis occurs as a single verrucous lesion over exposed areas of the body along with inflammatory borders and discharging sinus. Here, we are presenting a rare case of tuberculosis verrucosa cutis developing over a keloid. There is no report of such case in literature so far.
Recent Replica Placement Algorithms in P2P Networks – A Review
Kala Karun. A,Jayasudha. J. S
International Journal of Computer Network and Information Security , 2013,
Abstract: Peer-to-Peer (P2P) systems provide a platform for large internet scale distributed applications with no dedicated infrastructure. In P2P systems, applications are developed by dividing them across individual systems termed peers which take the role of both client as well as server. Popularity of objects in such a system can change rapidly, which demands the need for a rapid and light weight content replication strategy which considers this dynamic popularity changes. While considering P2P in distributed file sharing applications, data availability has significant impact on the system's performance. In addition to optimized availability, the replica placement should guarantee reduced search and data access latency. It should be dynamically adaptable to instantaneous query arrival rate as well as dynamic membership of individual peers. Also, it should provide good performance with reduced number of control messages. Thus an intelligent placement of replicas considering various factors of the system always outperforms a random placement of replicas on random peers. This paper reviews and compares various recent replica placement algorithms for structured as well as unstructured P2P networks.
Traditional Ecological Knowledge, Sacred Groves and Conservation of Biodiversity in the Pachmarhi Biosphere Reserve of India  [PDF]
Chandra Prakash Kala
Journal of Environmental Protection (JEP) , 2011, DOI: 10.4236/jep.2011.27111
Abstract: The sacred groves in the Pachmarhi Biosphere Reserve (PBR) of India were studied to understand the concept of traditional ecological and biodiversity conservation systems. A questionnaire survey was conducted in the selected villages of the PBR along with the survey of sacred groves. In 10 selected villages of the PBR 7 sacred groves were managed by Mawasi and 16 sacred groves by Gond tribal communities. Different deities were worshipped in the sacred groves and each grove was named after the deity dwelling in the respective sacred grove. A total of 19 such deities were recorded during the survey worshipped by the local people. In study area, various traditional customs associated with sacred groves were in practice. The sacred groves were rich in plant genetic diversity and were composed of many ethnobotanically useful species, including wild edible fruits, medicinal plants, fodder, fuelwood and timber yielding species. Given the importance of conservation of biodiversity and ecosystem attempts should be made to maintain the sanctity of sacred groves.
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