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Search Results: 1 - 10 of 1627 matches for " Martina Danihelová "
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NUTRITIONAL AND HEALTH BENEFITS OF BUCKWHEAT
Martina Danihelová,Ernest ?turdík
Potravinarstvo : Scientific Journal for Food Industry , 2012, DOI: 10.5219/206
Abstract: Buckwheat represents a raw material interesting in term of its nutritional and health beneficial suitability. Buckwheat grain is a source of valuable proteins, starch with low glycemic index or high amount of unsaturated fatty acids. It contains compounds with prophylactic value, too. Buckwheat is one of the richest sources of flavonoids. The highest content of dietary fibre is in bran fraction, where it counts for 40 %. Present phytosterols are usefull in lowering blood cholesterol. Buckwheat is better source of magnesium, potassium, phosphorus, zinc, manganese and copper than other cereals. Among vitamins the most abundant is pyridoxin. Buckwheat is effective in management of many diseases, mainly cardiovascular and digestion disorders, cancer, diabetes and obesity. In the last decades buckwheat is an interesting material not only for development of new functional foods, but for the preparation of concentrates with healing buckwheat components, too. doi:10.5219/206
Antioxidant and antiproteinase effects of buckwheat hull extracts
Martina Danihelová,Ernest ?turdík
Potravinarstvo : Scientific Journal for Food Industry , 2013, DOI: 10.5219/272
Abstract: Buckwheat is known not only due to its appropriate nutritional composition but the content of prophylactic compounds, too. These are responsible for buckwheat beneficial impact on human health. Most of them are concentrated in outer layers of buckwheat grain. The subject of this work was to screen hulls of nine common and one tartary buckwheat cultivar for the content of flavonoids and its antioxidant and antiproteinase effects. The highest content of total flavonoids was determined for tartary buckwheat cultivar Madawaska (0.6% of hulls weight). Among common buckwheat cultivars the best values reached samples Bamby (0.23%) and KASHO-2 (0.11%). Antioxidant activity as detected via binding radical ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)) and monitoring reducing power was the most effective for samples with highest flavonoid content. Buckwheat hulls effectively inhibited pathophysiological proteases thrombin and urokinase, whereas only little effects were seen to trypsin and elastase. In this testing there were again the best samples with highest flavonoid content. Only tartary buckwheat Madawaska effectively inhibited elastase at tested concentrations. No significant correlation was determined between flavonoid content and measured antioxidant or protease inhibitory action. Obtained results allow us to commend tartary buckwheat cultivar Madawaska as well as common buckwheat cultivars Bamby and KASHO-2 for further experiments. doi:10.5219/272
FLAVONOID NATURAL SOURCES AND THEIR IMPORTANCE IN THE HUMAN DIET
Martina Danihelová,Ernest ?turdík
Potravinarstvo : Scientific Journal for Food Industry , 2011, DOI: 10.5219/160
Abstract: Flavonoids as natural bioactive compounds are present in almost every sort of fruits, vegetables and from them derived products. Flavonols may be found mainly in fruits and vegetables, while flavones are abundant in herbs and spices. Rich natural sources of flavanols are tea, cocoa, grape seeds or apple skin. Flavanones are primarily found in a variety of citrus fruits and anthocyanidins in many coloured berries. Soy is rich in isoflavonoids. Average daily intake of flavonoids is approximately in the range of 150 to 300 mg. It strongly depends on individual, country and culture usages. In west countries main dietary sources of flavonoids consist of tea, wine and fruits, while in east countries there is consumed mainly soy with high isoflavonoid content. Many studies have shown, that intake of fruits and vegetables with high flavonoid content is associated with lowered risk of incidence of some diseases such as cardiovascular or cancer. These findings are attributed to experimentally confirmed biological effects of flavonoids - antioxidant, anti-inflammatory, anti-allergic, anticancer or cardioprotective. The final effect is however depending on their bioavailability, which is in the case of flavonoids not high, because in the nature dominating flavonoid glycosides can poorly penetrate through lipophilic cell membranes. Final effective molecules are flavonoid metabolites, that more or less retain their biological activities. doi: 10.5219/160
Lipophilization of flavonoids for their food, therapeutic and cosmetic applications
Martina Danihelová , Jana Viskupi ová , , Ernest turdík
Acta Chimica Slovaca , 2012, DOI: 10.2478/v10188-012-0010-6
Abstract: Flavonoids represent large group of plant pigments. These polyphenolic compounds may be found in the nature as active components of fruits, vegetables and other plants and derived products. Due to established biological effects they are attractive substances for many areas of human life. Many flavonoids are nowadays used in pharmaceutical, cosmetic and food preparations. Their practical applications are in most cases limited by low solubility and stability in lipophilic media. Chemical or enzymatic lipophilization of flavonoid skeleton may not only increase their solubility and stability in lipophilic environment but also their biological properties. This review summarizes current knowledge in this field.
Forest stand height determination from low point density airborne laser scanning data in Roznava Forest enterprise zone (Slovakia)
Smre?ek R,Danihelová Z
iForest : Biogeosciences and Forestry , 2013, DOI: 10.3832/ifor0767-006
Abstract: The presented paper discusses the potential of low point density airborne laser scanning (ALS) data for use in forestry management. Scanning was carried out in the Ro nava Forest enterprise zone, Slovakia, with a mean laser point density of 1 point per 3 m2. Data were processed in SCOP++ using the hierarchic robust filtering technique. Two DTMs were created from airborne laser scanning (ALS) and contour data and one DSM was created using ALS data. For forest stand height, two normalised DSMs (nDSMs) were created by subtraction of the DSM and DTM. The forest stand heights derived from these nDSMs and the application of maximum and mean zonal functions were compared with those contained in the current Forest Management Plan (FMP). The forest stand heights derived from these data and the application of maxima and mean zonal functions were compared with those contained in the current Forest management plan. The use of the mean function and the contour-derived DTM resulted in forest stand height being underestimated by approximately 3% for stands of densities 0.9 and 1.0, and overestimated by 6% for a stand density of 0.8. Overestimation was significantly greater for lower forest stand densities: 81% for a stand density of 0.0 and 37% for a density of 0.4, with other discrepancies ranging between 15 and 30%. Although low point density ALS should be used carefully in the determination of other forest stand parameters, this low-cost method makes it useful as a control tool for felling, measurement of disaster areas and the detection of gross errors in the FMP data. Through determination of forest stand height, tree felling in three forest stands was identified. Because of big differences between the determined forest stand height and the heights obtained from the FMP, tree felling was verified on orthoimages.
Interactive Methods of Teaching Physics at Technical Universities
?ubo? Kri??ák,Miroslav Němec,Zuzana Danihelová
Physics , 2013,
Abstract: The papeer presents results of "non-traditional" teaching of basic course of Physics in the first year of study at the Technical University in Zvolen, specifically teaching via interactive method based on an increased focus on problem tasks and experiments. This paper presents also research results of the use of the given method in conditions of Slovak universities and its comparision with traditional methods.
Alternative UV Sensors Based on Color-Changeable Pigments  [PDF]
Martina Vikova, Michal Vik
Advances in Chemical Engineering and Science (ACES) , 2011, DOI: 10.4236/aces.2011.14032
Abstract: Photochromism is a chemical process in which a compound undergoes a reversible change between two states having separate absorption spectra, i.e. different color [1]. In our previous work we have published some solutions of problems of measuring photochromic textile sample by standard commercial spectrophotometric systems [2]. Main problem with measurement of kinetic behavior of photochromic pigments by standard spectrophotometer is relatively long time period between individual measurements (5 s) and impossibility of measuring whole color change during exposure without interruption of illumination of sample during measurement. It means, standard commercial spectrophotometers enable off-line measurement of kinetic behavior during exposure period and quasi on-line measurement during reversion period. Based on this problem, it is only possible to obtain precise data during reversion—decay process and growth process (exposure) is affected by high variability of data. Following this knowledge, we developed original experimenttal system with short time scanning of color change of photochromic samples during growth and decay period of color change. In this study it is presented new view on the relationship between intensity of UV-A radiation and color change half-life t1/2. Via this relation, it is demonstrated the possibility of the flexible textile-based sensors construction in the area of the radiation intensity identification.
Direct Infection and Replication of Naturally Occurring Hepatitis C Virus Genotypes 1, 2, 3 and 4 in Normal Human Hepatocyte Cultures
Martina Buck
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0002660
Abstract: Background Hepatitis C virus (HCV) infection afflicts about 170 million individuals worldwide. However, the HCV life cycle is only partially understood because it has not been possible to infect normal human hepatocytes in culture. The current Huh-7 systems use cloned, synthetic HCV RNA expressed in hepatocellular carcinoma cells to produce virions, but these cells cannot be infected with naturally occurring HCV obtained from infected patients. Methodology/Principal Findings Here, we describe a human hepatocyte culture permissible to the direct infection with naturally occurring HCV genotypes 1, 2, 3 and 4 in the blood of HCV-infected patients. The culture system mimics the biology and kinetics of HCV infection in humans, and produces infectious virions that can infect na?ve human hepatocytes. Conclusions/Significance This culture system should complement the existing systems, and may facilitate the understanding of the HCV life cycle, its effects in the natural host cell, the hepatocyte, as well as the development of novel therapeutics and vaccines.
Max Planck announces cuts
Martina Habeck
Genome Biology , 2003, DOI: 10.1186/gb-spotlight-20030611-01
Abstract: The announcement vindicates concerns expressed in December 2002, when the German government decided to freeze the budgets of the public research organizations at 2002 levels. Since then, chancellor Gerhard Schr?der has promised a 3% budget increase per year beginning in 2004. But in order to fund its 80 research institutes and 12,000 employees, the MPG needs an annual budget increase of at least 4%."The freeze really hurts," Christina Beck of the MPG told The Scientist, "because it actually means less money, not least because of increased personnel costs due to tariff rises." She added that recruiting a new research director now costs roughly 1.3 times more than in the past. This means funding for only three new directors when four directors retire.The budget freeze came at a time when the MPG was already struggling financially. In the 1990s, it received extra funding to pay for its part in "Aufbau Ost," the rebuilding of eastern Germany. The MPG opened 20 new research institutes in the new L?nder; the last building works were only finished this year, and nine of 57 research director positions at the new institutes in the east still need to be filled. But the extra funding for Aufbau Ost dried up in 2000, and the MPG drew criticism from research minister Edelgard Bulmahn for having taken so much time and having wasted funds in the early 1990s."It is easy to say that we were too slow," countered Beck. "I would say we have been careful and thorough. The MPG is well advised to take its time in choosing directors carefully, if it wants to keep its international reputation for conducting excellent research."In order to continue to be able to afford the best scientists, the MPG decided to adopt a strategy of cuts that wouldn't compromise its reputation. It identified department directors due for retirement by 2007 and then assessed the potential of the research in those departments. "We wondered where we can expect scientific breakthroughs in the next few years," explaine
Swiss computing center opens
Martina Habeck
Genome Biology , 2003, DOI: 10.1186/gb-spotlight-20040428-02
Abstract: Inaugurated last Thursday (April 22), the Lausanne-based Vital-IT center is equipped with two HP clusters of 32 production and 8 development servers, based on Intel's Itanium 2 processor. These kinds of clusters allow life scientists to run complicated software 10 to 50 times faster, thereby opening new research avenues, says Christos Ouzounis at the European Bioinformatics Institute. "You can think of problems that you could not think of otherwise if you had a limited computational capacity," he told us.The impact of the new computing power may soon be felt not only by scientists directly associated with Vital-IT, but by researchers worldwide who use the services available through the Swiss Institute of Bioinformatics, such as proteomics tools on the ExPASy (Expert Protein Analysis System) servers.The Vital-IT center also employs four information technology specialists who have access to the full technological know-how of Intel and HP. According to the center's director, Victor Jongeneel, a major aim is to develop software for the life sciences that is more robust and that performs better than the current programs, which are often written by people who are not professional programmers.The new software will run on the Itanium 2 architecture, which has been on the market for 2 years. The technology is particularly suited for large-scale computational problems; however, its uptake has been slow, partly because there is not much software that runs on it."We took a chance in deciding to go for machines that have this chip," concedes Jongeneel. "But rather than going with legacy technology, even though it is very fast right now, we [have gone] with technology that is maybe a little more expensive and with a slightly lower performance right now, with the idea that 5 years from now, we will have gone beyond all the problems associated with it, while other centers will be struggling to keep up."
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