oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2020 ( 11 )

2019 ( 433 )

2018 ( 519 )

2017 ( 535 )

Custom range...

Search Results: 1 - 10 of 325348 matches for " Martie S. Lubbe "
All listed articles are free for downloading (OA Articles)
Page 1 /325348
Display every page Item
The prevalence of side-effects: ciprofloxacin 500 mg single dose prophylaxis against Neisseria meningitidis outbreak in Potchefstroom during July 2003: research
Michelle Viljoen, Martie S Lubbe, Rina Meyer
Health SA Gesondheid , 2004,
Abstract: Potchefstroom experienced an outbreak of Neisseria meningitidis (N. meningitidis) during May-July 2003. An opportunity for obtaining valuable data arose when mass prophylactic treatment to approximately 28% of the Potchefstroom community was provided by the Department of Health, North-West Province. The aim of this study was to investigate the prevalence of side-effects experienced by staff and students of the Potchefstroom University for Christian Higher Education (PU for CHE) who received a single prophylactic dose of oral ciprofloxacin 500 mg between 23 and 29 July 2003. Information gained from the Potchefstroom outbreak may be valuable for the future management of similar outbreaks in other communities. Various stakeholders have published related reports, protocols, recommendations and guidelines, which mostly focused on the prevention, management and control of meningococcal disease. Very little has been reported about the side-effects experienced, especially in cases where ciprofloxacin 500 mg single dose had been dispensed. One or more side-effects were reported by 24.2% of the participants, while 5.4% had to consult with a health care worker due to the severity of side-effects resulting from a single dose. Practical significance could not be demonstrated for any of the side-effects reported after single versus multiple doses nor when the effects of gender or requirement for medical consultation were tested. Key Words: Neisseria meningitidis; Ciprofloxacin; Single dose; Side effects; Prophylactic OPSOMMING ‘n Uitbraak van Neisseria meningitidis (N. meningitidis) gedurende Mei-Julie 2003 en die daaropvolgende verskaffing van massa-profilakse deur die Departement van Gesondheid, Noordwesprovinsie aan ongeveer 28% van die plaaslike gemeenskap het ‘n geleentheid geskep om waardevolle inligting in te win. Die doel van die studie was om die voorkoms van newe-effekte te ondersoek wat deur die personeel en studente van die Potchefstroomse Universiteit vir Christelike Ho r Onderwys ervaar is na toediening van ‘n enkel profilaktiese dosis van siprofloksasien 500 mg tussen 23-29 Julie 2003. Inligting wat hieruit voortspruit mag waardevol wees tydens toekomstige bestuur van uitbrake in ander gemeenskappe. Verskillende belanghebbendes het verslae, protokolle, aanbevelings en riglyne gepubliseer, wat meestal op die voorkoming, bestuur en beheer van meningokokkale siekte gefokus het. Daar is egter min gerapporteer oor die newe-effekte wat ondervind is veral waar siprofloksasien 500mg enkeldosis toegedien is. Een of meer newe-effekte is deur 24.2% van die deelnemers ervaar en 5.4% het dit nodig geag om ‘n gesondheidswerker te konsulteer in verband met die newe-effekte wat ervaar is. Geen prakties betekenisvolle verskille is aangedui indien die effeksgrootte bereken is vir die newe-effekte getoets tussen die enkeldosis versus die meervoudige dosis nie, selfs ook nie nadat die effek van geslag of konsultasie getoets is nie. Health SA Gesondheid Vol.9(3) 200
The prevalence of side-effects: Ciprofloxacin 500 mg single dose prophylaxis against Neisseria Meningitidis outbreak in Potchefstroom during July 2003
Michelle Viljoen,Martie S Lubbe,Rina CL Meyer
Health SA Gesondheid , 2004, DOI: 10.4102/hsag.v9i3.171
Abstract: Potchefstroom experienced an outbreak of Neisseria meningitidis (N. meningitidis) during May-July 2003. An opportunity for obtaining valuable data arose when mass prophylactic treatment to approximately 28% of the Potchefstroom community was provided by the Department of Health, North-West Province. Opsomming ‘n Uitbraak van Neisseria meningitidis (N. meningitidis) gedurende Mei-Julie 2003 en die daaropvolgende verskaffing van massa-profilakse deur die Departement van Gesondheid, Noordwesprovinsie aan ongeveer 28% van die plaaslike gemeenskap het ‘n geleentheid geskep om waardevolle inligting in te win. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.
Prescribing patterns of antiretroviral drugs in a section of the private health care sector of South Africa
Danie Scholtz,Martie S Lubbe,Jan HP Serfontein,Dorcas Rakumakoe
Health SA Gesondheid , 2006, DOI: 10.4102/hsag.v11i4.230
Abstract: The general objective of this study was to investigate the prescribing patterns and cost of antiretroviral (ARV) drugs in the private health care sector in South Africa by using a medicine claims database. Opsomming Die doel van hierdie studie was om die voorskryfpatrone en medisynekoste van antiretrovirale (ARV) geneesmiddels in die private gesondheidsorgsektor in Suid-Afrika te ondersoek. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.
Therapeutic budget modelling: a possible road to budgetary allocations in the public health care setting
George K John,Martie S Lubbe,Jan HP Serfontein
Health SA Gesondheid , 2007, DOI: 10.4102/hsag.v12i2.248
Abstract: In South Africa, 70% of the country’s population is dependent on the public health care sector (especially the primary health care structure) for their basic health care needs. Opsomming In Suid-Afrika is 70% van die land se bevolking van die openbare gesondheidsorgsektor (veral die primêre gesondheidsorgstruktuur) afhanklik vir hulle basiese behoeftes aan gesondheidsorg. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.
Investigation into the prescribing patterns and cost of antidiabetic medicine in South Africa
Rianda Steyn,Johanita R Burger,Jan HP Serfontein,Martie S Lubbe
Health SA Gesondheid , 2007, DOI: 10.4102/hsag.v12i3.262
Abstract: The general objective of this study was to investigate the prescribing patterns and cost of antidiabetic medicine in the private health care sector in South Africa by using a medicine claims database. Opsomming Die algemene doelstelling van hierdie studie was om die voorskryfpatrone en koste van antidiabetiese medisyne in die private gesondheidsorgsektor van Suid-Afrika te ondersoek. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.
Antimicrobial prescribing patterns in a group of private primary health care clinics in South Africa
Norah L Katende-Kyenda,Martie S Lubbe,Jan HP Serfontein,Ilse Truter
Health SA Gesondheid , 2007, DOI: 10.4102/hsag.v12i1.240
Abstract: The aim of this study was to investigate the prescribing of antimicrobials in private primary health care in South Africa. ABSTRAK Die doel met hierdie studie was om die voorskryfpatrone van antimikrobiese middels in private primêre gesondheidsorginrigtings in Suid-Afrika te ondersoek.
Factors influencing access to pharmaceutical services in underserviced areas of the West Rand District, Gauteng Province, South Africa
Ditonkana A. Sello,Jan H.P. Serfontein,Martie S. Lubbe,Yoswa M. Dambisya
Health SA Gesondheid , 2012,
Abstract: The study examined demographic and socio-economic factors that may influence pharmaceutical services (PS) in underserviced communities of the West Rand District, Gauteng Province, South Africa. A quantitative survey was conducted using structured questionnaires administered to the general public (n = 2014) in Bekkersdal, Kagiso, Mohlakeng, Munsville and Diepsloot townships. The questionnaire explored demographic details, employment and education status, income levels, payment methods and convenience of services. Of the respondents, 54.0% were women, 52.0% were unemployed; 65.0% had secondary educationor higher and > 70.0% had no income or earned < R1000 p.m. Unemployment was higher amongst women. Only 13.9% of respondents had medical aid membership, which influenced their choice of health provider, with the exception of pharmacy services which are notaffected by medical aid membership. Medical aid members were, however, more able to pay. Employment status and education also influenced the choice of provider, with most of the employed (66.0%) and educated (64.4%) preferring a pharmacy or GP. On pharmacist gender, 47.5% of respondents had no preference, 27.6% preferred male pharmacists, whilst 24.9% preferred female pharmacists. Men with preferences preferred male providers (77.0%), whilst female respondents preferred female providers (69.3%). Respondents with no formal education and those with low or no income expressed higher gender preferences rates than those with formal education or higher income, respectively. Thus, access to PS was influenced by gender, age, family income and education level. Whilst medical aid membership had no influence on access to PS, it influenced ability to pay. These factors should be considered by those wishing to offer PS in such areas.
Analysis of possible drug-drug interactions between ritonavir and other antiretrovirals in a section of the private health care sector in South Africa
Norah L. Katende-Kyenda,Martie S. Lubbe,Jan H.P. Serfontein,Ilse Truter
African Journal of Primary Health Care & Family Medicine , 2009, DOI: 10.4102/phcfm.v1i1.21
Abstract: Background: The introduction of human immunodeficiency virus (HIV) protease inhibitors (PIs) has led to a dramatic decline in the morbidity and mortality associated with HIV infection. However, the concomitant use of PIs and other antiretrovirals (ARVs) can be complicated by drug-drug interactions (DDIs), adversely affecting levels of PIs. Method: A quantitative, retrospective drug utilisation study was performed using data obtained from the medicine claims database of a pharmacy benefit management company during 2004, 2005 and 2006. The possible DDIs found among ARVS themselves were identified using the classification by Tatro. Results: The percentage of ARV prescriptions claimed of the total number of medicine items increased from 1.68% (n = 43 482) during 2004 to 3.18% (n = 51 613) during 2005, then to 4.74% (n = 47 085) during 2006. A total of 1 326, 1 863 and 960 possible DDIs were identified among ARVs themselves for 2004, 2005 and 2006 respectively. Of these, ritonavir (unboosted or boosted) presented with the most possible DDIs, accounting for 74.28% (n = 985) for 2004; 67.90% (n = 1 265) for 2005; and 27.50% (n = 264) for 2006. The highest prevalence of DDIs identified was between ritonavir (unboosted) and saquinavir (n = 974, 5) for 2005 and 2006; followed by indinavir (n = 490, 129, 155) for 2004 to 2006; and efavirenz (n = 274) for only 2004; then ritonavir (boosted), co-formulated as lopinavir/ritonavir, and efavirenz (n = 118, 88, 34) for 2004 to 2006; nevirapine (n = 49, 37) for 2004 and 2005; indinavir (n = 9) for 2004; and saquinavir (n = 22) for 2006. Conclusion: These findings indicate that concomitant use of PIs such as ritonavir, a potent cytochrome P450(CYP)3A4 enzyme inhibitor, and other ARVs is complicated by possible DDIs and therefore further studies need to be done on the ARV combinations and management of these DDIs. How to cite this article: Katende-Kyenda NL, Lubbe MS, Serfontein JHP, Truter I. Analysis of possible drug-drug interactions between ritonavir and other antiretrovirals in a section of the private health care sector in South Africa. Afr J Prm Health Care Fam Med. 2009;1(1), Art. #21, 6 pages. DOI: 10.4102/phcfm.v1i1.21
Management information searching for decision making
S. Lubbe
South African Journal of Information Management , 2009, DOI: 10.4102/sajim.v6i3.309
Abstract:
Development of a case study methodology in the information technology (IT) field in South Africa: a step-by-step approach
S. Lubbe
South African Journal of Information Management , 2010, DOI: 10.4102/sajim.v5i4.380
Abstract:
Page 1 /325348
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.