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Search Results: 1 - 10 of 17853 matches for " Mark Tagoe "
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Transmetatarsal Amputation: A Case Series and Review of the Literature
Ryan McCallum,Mark Tagoe
Journal of Aging Research , 2012, DOI: 10.1155/2012/797218
Abstract: Foot ulceration is a major cause of morbidity amongst patients with diabetes. In severe cases of ulceration, osteomyelitis and amputation can ensue. A distinct lack of agreement exists on the most appropriate level of amputation in cases of severe foot ulceration/infection to provide predictable healing rates. This paper provides an overview of the transmetatarsal amputation (TMA) as a limb salvage procedure and is written with the perspective and experiences of the Department of Podiatric Surgery at West Middlesex University Hospital (WMUH). We have reflected on the cases of 11 patients (12?feet) and have found the TMA to be an effective procedure in the management of cases of severe forefoot ulceration and infection. 1. Introduction In recent times, increased attention has been placed on the alarming increase in the incidence of diabetes. Diabetic foot ulcers occur in up to 15% of diabetic patients [1], and amputation rates amongst this population have been documented as 11% [2]. In particular cases of severe foot infection, amputation should not necessarily be looked upon as failure of care, but rather the most appropriate intervention for preventing more proximal spread and persistent hospital attendance. Aggressive management of severe foot infection/ulceration can reduce the risk of proximal amputation. 2. Transmetatarsal Amputation A proportion of the diabetic community experience serious and debilitating complications associated with their feet, with a 12–25% increased risk of developing foot ulceration [3]. Development of diabetic foot ulceration is often a multifactorial process; however, the presence of influences such as neuropathy and peripheral vascular disease is recognised as significant contributing factor. The neuroischaemic ulceration accounts for 90% of those encountered in the diabetic population [4], and approximately half of diabetic foot wounds develop an infection, the majority involving only soft tissue [5]. In circumstances where soft tissue infection is severe or where underlying bone is infected, amputation may be considered an appropriate line of treatment. Mills et al. [6] recognised that infection and gangrene due to microvascular disease were two major factors that resulted in failure of wound healing, resulting in amputation. At WMUH, a treatment pathway has been developed for patients with severe foot ulceration/infection who have been deemed suitable candidates for undergoing TMA (see Assessment and Treatment below). Patients are urgently admitted into the hospital and are assessed by the medical and surgical teams,
Differences in Acute Phase Reactants between Gout and Pseudogout  [PDF]
Clement E. Tagoe, Yasmin Raza
International Journal of Clinical Medicine (IJCM) , 2013, DOI: 10.4236/ijcm.2013.412A2003

Objectives: To define clinical differences in the acute phase response and serum acute phase reactants between gout, pseudogout and crystal-induced arthritis in the presence of non-articular infections (CAI). Patients and Methods: Eleven patients with definite gout, 12 patients with pseudogout and 5 patients with CIA were included in the study. Results: The erythrocyte sedimentation rate (ESR) was significantly different between gout (68.2 ± 49.9 mm/Hr) and CIA (113.8 ± 37.2 mm/Hr) but not between gout and pseudogout (83.9 ± 45.6 mm/Hr) or between pseudogout and CIA. The C-reactive protein (CRP) was significantly increased between gout (10.1 ± 7.9 mg/dL) and pseudogout (18.9 ± 9.8 mg/dL), gout and CIA (36.5 ± 12.4 mg/dL) as well as between pseudogout and CIA. The peripheral white cell count was significantly different between gout (9.27 ± 3.7 k/μL) and CIA (16.5 ± 6.8 k/μL), and between pseudogout (8.9 ± 3.2 k/μL) and CIA. Conclusions: Measurement of ESR and CRP are helpful in crystal-induced arthritis. The CRP has more discriminating utility than the ESR in distinguishing between gout, pseudogout and CIA. Peripheral wbc is most useful for differentiating crystal-induced arthritis from CIA.

The double-edged sword: financial source of household healthcare expenditure in Ghana
Henry Armah Tagoe
Journal of Public Health in Africa , 2012, DOI: 10.4081/jphia.2012.e17
Abstract: In many regions, some of the most formidable enemies of health are joining forces with the allies of poverty to impose a double burden of disease, disability and premature death. This paper looks at the main financial sources households use to finance healthcare in Ghana. It examines the spatial and socio-economic dynamics and the challenges these pose to health and development. Analysis of the 2003 Ghana World Health Survey data indicates that approximately 41% of households depend on more than one financial source with 88% depending on household income to finance healthcare expenditure. The high dependency on household income will erode gains in the economic and health sector in the midst of the recent global economic recession. Comprehensive national health insurance programs that cover emerging disease conditions will mitigate the double burden of disease on households in emerging economies.
Imaging and Dosimetric Consideration for Titanium Prosthesis Implanted within the Irradiated Region by Cobalt-60 Teletherapy Unit  [PDF]
Vaino Indongo, Samuel Nii Adu Tagoe, Kwame Kyere, Cyril Schandorf
International Journal of Medical Physics,Clinical Engineering and Radiation Oncology (IJMPCERO) , 2018, DOI: 10.4236/ijmpcero.2018.72014
Abstract: The aim of this research is to observe dose distributions in the vicinity of titanium prosthetic implants during radiotherapy procedures on 60Co teletherapy machine, Prowess Panther treatment planning system (TPS). Data were obtained using a locally fabricated tissue equivalent phantom CT images with titanium prosthesis which was irradiated with 60Co gamma radiation. Prowess TPS (1.25 MeV) estimated less variations. Proximal ends of the metal recorded slight increase in doses as a result of backscatter with dose increment below acceptable tolerance of ±3%. Doses measured decreases on the distal side of the prosthesis at a distance less than dmax from the plate on each beam energy. The depth dose increases marginally after a certain depth level which generally originated from the unperturbed dose due to increase in the electron fluence. The percentage of depth doses decrease with the increase in plate thickness. A reduction in the above trend was also noticed with an increase in beam energy primarily because scattered photons are more forwardly directed. Prowess TPS (convolution superposition algorithm) was found to be better at reducing dose variation when correction for artifact. Manual calculations on blue phantom data agree with results from Prowess. This treatment system is capable of simulating dose around titanium prosthesis as its range of densities, 0.00121 to 2.83, excludes titanium density (rED for titanium is 3.74).
Healthy lifestyle behaviour among Ghanaian adults in the phase of a health policy change
Henry A Tagoe, Fidelia AA Dake
Globalization and Health , 2011, DOI: 10.1186/1744-8603-7-7
Abstract: Descriptive, bivariate and multivariate regression techniques were employed on two nationally representative surveys (2003 World Health Survey (Ghana) and 2008 Ghana Demographic and Health Survey) to arrive at the results.While the prevalence of some negative lifestyle behaviours like smoking has reduced others like alcohol consumption has increased. Relatively fewer people adhered to consuming the recommended amount of fruit and vegetable servings per day in 2008 compared to 2003. While more females (7.0%) exhibited healthier lifestyles, more males (9.0%) exhibited risky lifestyle behaviours after the introduction of the policy.The improvement in healthy lifestyle behaviours among female adult Ghanaians will help promote healthy living and potentially lead to a reduction in the prevalence of obesity among Ghanaian women. The increase in risky lifestyle behaviour among adult male Ghanaians even after the introduction of the health policy could lead to an increase in the risk of non-communicable diseases among men and the resultant burden of disease on them and their families will push more people into poverty.The overall health of individuals is impacted by lifestyle behaviours including healthy diets, physical activity, smoking and alcohol consumption. Unhealthy lifestyle behaviours particularly poor dietary practices, physical inactivity and smoking are major risk factors for conditions like overweight, obesity and chronic non-communicable diseases [1-3]. Research in Ghana indicates that the prevalence of obesity is increasing especially among women [4]. The rising prevalence of obesity in Ghana is worrying because epidemiological studies have consistently shown an increased risk of morbidity, disability and mortality with obesity [5]. Findings from a study using data from a nationally representative sample survey (World Health Survey 2003) conducted in Ghana revealed that about 18% of the respondents had been diagnosed with one or more chronic non-communicable di
Birth and Emergency Planning: A Cross Sectional Survey of Postnatal Women at Korle Bu Teaching Hospital, Accra, Ghana
EA Udofia, SA Obed, BNL Calys-Tagoe, KP Nimo
African Journal of Reproductive Health , 2013,
Abstract: Birth and emergency planning encourages early decision making, helps overcome barriers to skilled maternity care and reduces preventable maternal and newborn deaths. A facility based postnatal survey of 483 childbearing women in Accra, Ghana determined birth and emergency planning steps, awareness of obstetric danger signs, reported maternal and newborn complications and birth outcome based on length of hospital stay. Supervised antenatal care and delivery were nearly universal. Overall, 62% had a birth plan, 74% had adequate knowledge of danger signs, while 64% and 37% reported maternal and newborn complications respectively. Accompaniment by a birth companion and saving money were considered the most useful planning steps. Knowledge of danger signs was associated with birth and emergency planning, and birth and emergency planning was associated with reported birth outcome. Birth and emergency planning as a critical component of antenatal care can influence birth outcomes and should be extended to all pregnant women. Résumé La planification des naissances et d'urgence encourage la prise de décision rapide, aide à surmonter les obstacles aux soins de maternité qualifiés et réduit les décès maternels et néonatals évitables. Une enquête post-natale qui a été basée sur l’établissement, et auprès des 483 femmes en age de procréer à Accra, au Ghana a déterminé les étapes de planification des naissances et d'urgence, la sensibilisation des signes de danger obstétrical, a rapporté des complications maternelles et néonatales et les résultats des naissances selon la durée du séjour à l'h pital. Les soins prénatals et l'accouchement surveillés étaient presque universels. Dans l'ensemble, 62% avaient un plan de naissance, 74% avaient une connaissance adéquate des signes de danger, tandis que 64% et 37% ont déclaré des complications maternelles et néonatales, respectivement. Le fait d’être accompagné par un compagnon de naissance et d’économiser de l'argent ont été considérés comme les étapes de planification les plus utiles. La connaissance des signes de danger a été associée à la naissance et à la planification d'urgence et la planification des naissances et d'urgence a été associée à des résultats des naissances déclarées. La planification des naissances et d'urgence comme un élément essentiel des soins prénatals peuvent influer sur les résultats de grossesses et devrait être mis a la portée de toutes les femmes enceintes.
Potential sources of transmission of hospital acquired infections in the volta regional hospital in Ghana
DNA Tagoe, SE Baidoo, I Dadzie, D Tengey, C Agede
Ghana Medical Journal , 2011,
Abstract: Background: The study was undertaken to assess potential sources that might transmit Hospital Acquired Infections in the Volta Regional Hospital of Ghana. Method: A total of 218 swabs were taken over a six month study period of two weeks sampling bi-monthly from 33 different door handles, taps, desk surfaces and lavatories and 15 different surfaces in the theatre before and after cleaning on each sampling day. The swabs were cultured on Blood, Chocolate and Mac-Conkey agars and incubated for 24hrs at 35±2oC afterwhich isolates were identified morphologically and biochemically. Results: A total of 187 (88.8%) bacterial isolates were obtained from the swabs (P<0.0017) made up of 55.5% non-pathogenic isolates, 33.3% pathogenic isolates and 14.2% no bacteria growth. There was significant difference between pathogenic isolates and no bacterial growth (P=0.0244). The largest pathogenic isolates were S. aureus (57.6%) and E. coli (39.4%) whilst Bacillus spp. was the only non-pathogenic isolate. Door handles of the various wards and theatre had the highest total bacterial isolates (25.7%), followed by the lavatories (24.6%); whereas the lavatories recorded the most pathogenic isolate (21), followed by taps. There was no change in S. aureus isolate numbers after cleaning whereas E. coli decreased by (26.7%) and Bacillus spp. increase by (32.7%). Conclusion: The high percentage of pathogenic isolates of S. aureus and E. coli as well as Bacillus spp. on fomites at the Volta Regional Hospital indicates a high potential risk of HAI in the hospital.
GIS in Water Supply Network Maintenance in Tarkwa, South Western Ghana
Michael Soakodan Aduah,Saviour Mantey,Naa Dedei Tagoe
Research Journal of Environmental and Earth Sciences , 2011,
Abstract: Developing systems to manage and maintain water supply networks is an important aspect of the operations of water companies. This study uses GIS to investigate the water supply network of a section of Tarkwa Municipality in South Western Ghana. The objective is to create a geodatabase that supports improved operations and performance and to determine costs of asset replacement. Digital maps of the study area were re-projected to the WGS84 UTM Zone 30 North projection. Analogue maps of the mains and lateral pipelines were scanned and geo-referenced to this projection. The pipelines and valves were then manually digitized, their attribute tables created and a geodatabase model developed. The analysis indicates that more than half of the network is over-aged. Also of the 11 km of pipelines, more than 76% was laid in 1975 and 1978. AC and PVC pipes laid in 1975 and 1978 comprise 29 and 47% respectively while the rest of the study area is covered by AC and PVC pipes laid in 1987. This study also observed that the length of AC pipes have consistently reduced since 1975. The study has further demonstrated the suitability of GIS techniques in studying water distribution networks. The system developed three scenarios that can support the design of long term expansion and replacement action plans. The study also provides detailed spatially referenced information on pipelines and the associated cost of replacement as they reach the designed lifespan.
Mapping Land Surface Temperature and Land Cover to Detect Urban Heat Island Effect: A Case Study of Tarkwa, South West Ghana
Michael Soakodan Aduah,Saviour Mantey,Naa Dedei Tagoe
Research Journal of Environmental and Earth Sciences , 2012,
Abstract: Urban Heat Island (UHI) effect controls internal climates of buildings and affects energy use and comfort of urban dwellers. The objective of this study was to detect UHI from Land Surface Temperature (LST) and to investigate whether land cover has any influence on UHI in Tarkwa, South West Ghana using satellite remote sensing techniques. A Landsat 7 ETM+ image, DEM and meteorological data were used to generate a land cover map with the maximum likelihood classification algorithm whiles LST was modeled with the Landsat Plank’s curve. Validation of the LST map was achieved by comparing it with air temperature measured at the UMaT meteorological station. The mean modeled LST of 298.60 Kelvin compared well with the mean observed air temperature of 298.30 Kelvin. Furthermore, LST ranged between 289 and 305 Kelvin while urban areas and bare soils had higher LSTs than vegetated areas implying that higher NDVI areas are associated with lower temperatures. Hence, LST maps produced indicated the existence of UHI effect in the Tarkwa area. From the study it is evident that impervious and non-evaporative surfaces have high LSTs due to absence of vegetation. Therefore, uncontrolled land cover changes may intensify the UHI effect. The study has proven that remote sensing can be used in operational mapping of LST for climate studies, vegetation monitoring and detecting UHIs in the humid regions of Ghana. This confirms the important role Earth observation and geoinformation technology can play in environmental monitoring and management as global climate and land cover changes.
Screening of Anti-Infectives against Leishmania donovani  [PDF]
Henry Nettey, Grace Lovia Allotey-Babington, Benoit Banga Nguessan, Barima Afrane, Mustafa Tagoe, Anokye Ababio, Patience Botchway, Yvonne Darko, Clement Sasu, Alexander Nyarko
Advances in Microbiology (AiM) , 2016, DOI: 10.4236/aim.2016.61002
Abstract: Aim: To evaluate in vitro the effectiveness of several anti-infective agents alone and in combination against Leishmania donovani. Method: A convenient stratified sampling method was used to obtain selected anti-infective agents. For individual drug samples, Half Maximal Inhibitory Concentrations (IC50) were obtained using the broth dilution method. The IC50’s of the drugs which were active against L. donovani were used as reference values to prepare drug combinations for the modified microdilution checkerboard method. Results: Five (5) out of the fifty-six (56) drugs used showed activity (inhibition of cell growth) against L. donovani cells. They include Quinine sulphate (IC50 = 0.089 μg/ml), gentamicin (IC50 = 8.1 μg/ml), amodiaquine (IC50 = 138 μg/ml) and the two standard drugs: Amphotericin B (IC50 = 6.3 μg/ml) and Pentamidine (IC50 = 25 μg/ml). The remaining fifty-one (51) drugs did not show any inhibition within the range of concentrations used (1.25 - 160 μg/ml). The drug combinations of Pentamidine/Amodiaquine, Pentamidine/ Quinine sulphate, Pentamidine/Gentamicin, Amphotericin B/Quinine Sulphate, Amphotericin B/ Gentamicin, Amodiaquine/Quinine sulphate and Amodiaquine/Gentamicin showed synergistic effects against L. donovani whereas the Amphotericin B/Amodiaquine
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