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Search Results: 1 - 10 of 11215 matches for " Mario Baratta "
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Relationship between serum β-lactoglobulin content during gestation and reproductive efficiency in primiparous sows
Alberto Sabbioni,Mario Baratta,Matteo Lavarini,Valentino Beretti
Italian Journal of Animal Science , 2010, DOI: 10.4081/ijas.2004.219
Abstract: The relationship between β-lactoglobulin (β-LG) serum concentration in sows during the last 8 weeks of gestation and subsequent piglet performance was investigated in 10 Dunel gilts. Two classes of gilts were identified with low (<150 ng/ml) or high (>150 ng/ml) average serum β-LG content. For both low and high content groups, equations were calculated to describe trends in serum β-LG content, respectively y1=10.07e0.0237x (R2=0.3122) and y2=69.00e0.0201x (R2=0.6959), where x is the number of days of gestation. Differences in serum β-LG content between the two groups were highly significant at all weeks (P<0.01 from week 8 to 6 before farrowing; P<0.001 from week 5 to farrowing). No significant differences (P>0.05) between groups were shown for total number of piglets born, born alive, stillborn or mummified and piglet survival rates up until d 21 after farrowing. The group with high serum β-LG content during gestation showed higher litter weights at d 5 (P<0.05) and d 21 (P<0.10) and higher estimated milk production from farrowing to d 5 (P<0.10). The results indicate that serum β-LG content during the final weeks of gestation could be used as an early indicator of reproductive efficiency, and that gilts with high content could be selected to improve herd productivity.
Prediction of milk, fat and protein yields in first lactation from serum -lactoglobulin concentrations during gestation in Italian Brown heifers
Alberto Sabbioni,Mario Baratta,Valentino Beretti,Alessio Zanon
Italian Journal of Animal Science , 2010, DOI: 10.4081/ijas.2007.205
Abstract: The Authors report the results of a study carried out on 23 pregnant Italian Brown heifers, with the aim to determine the relationships between blood serum -lactoglobulin ( -LG) concentrations during first gestation and subsequent milk production and quality in first lactation, in order to obtain an improved selection method for replacement heifers. At weeks 20, 26 and 32 of gestation, -LG concentrations (±SE) were 706±78, 753±66 and 772±63 ng/ml, respectively (P>0.05). High and significant (P≤0.05) correlation coefficients were observed only between -LG content at week 32 and total milk and protein yields in first lactation. Prediction equations of milk, fat and protein production in first lactation from log10 -LG content at week 32 of gestation, from parent average genetic indexes and from both were calculated by means of multiple regression analysis. When the contribution of both -LG content and predicted genetic indexes were considered, the regression equations gave generally a better estimate of the production parameters in first lactation (higher R2, lower SE of estimate) than the above mentioned parameters alone. These results suggest that it is valuable to pre-estimate milk, fat and protein production in Italian Brown first lactating cows by means of the analysis of serum -LG content during gestation.
Met Receptor Acts Uniquely for Survival and Morphogenesis of EGFR-Dependent Normal Mammary Epithelial and Cancer Cells
Paolo Accornero, Silvia Miretti, Francesca Bersani, Elena Quaglino, Eugenio Martignani, Mario Baratta
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0044982
Abstract: Mammary gland development and breast cancer growth require multiple factors both of endocrine and paracrine origin. We analyzed the roles of Epidermal Growth Factor Receptor (EGFR) and Hepatocyte Growth Factor Receptor (Met) in mammary epithelial cells and mammary tumor cells derived from a mutated-ErbB2 transgenic mice. By using highly specific tyrosine kinase inhibitors we found that MCF-10A and NMuMG mammary epithelial cell lines are totally dependent on EGFR activation for their growth and survival. Proliferation and 3D-morphogenesis assays showed that HGF had no role in maintaining mammary cell viability, but was the only cytokine able to rescue EGFR-inhibited mammary cells. Insulin-Like Growth Factor-I (IGF-I), basic-Fibroblast Growth Factor (b-FGF) and Neuregulin, which are well known mammary morphogenic factors, did not rescue proliferation or morphogenesis in these cell lines, following EGFR inhibition. Similarly, ErbB2-driven tumor cells are EGFR-dependent and also display HGF-mediated rescue. Western-blot analysis of the signaling pathways involved in rescue after EGFR inhibition indicated that concomitant ERK1/2 and AKT activation was exclusively driven by Met, but not by IGF-I or b-FGF. These results describe a unique role for EGFR and Met in mammary epithelial cells by showing that similar pathways can be used by tumorigenic cells to sustain growth and resist to EGFR-directed anti-tumorigenic drugs.
Human Milk Protein Production in Xenografts of Genetically Engineered Bovine Mammary Epithelial Stem Cells
Eugenio Martignani,Peter Eirew,Paolo Accornero,Connie J. Eaves,Mario Baratta
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0013372
Abstract: In the bovine species milk production is well known to correlate with mammary tissue mass. However, most advances in optimizing milk production relied on improvements of breeding and husbandry practices. A better understanding of the cells that generate bovine mammary tissue could facilitate important advances in milk production and have global economic impact. With this possibility in mind, we show that a mammary stem cell population can be functionally identified and isolated from the bovine mammary gland. We also demonstrate that this stem cell population may be a promising target for manipulating the composition of cow's milk using gene transfer.
Atypical Antipsychotics in the Treatment of Depressive and Psychotic Symptoms in Patients with Chronic Schizophrenia: A Naturalistic Study
Marco Innamorati,Stefano Baratta,Cristina Di Vittorio,David Lester,Paolo Girardi,Maurizio Pompili,Mario Amore
Schizophrenia Research and Treatment , 2013, DOI: 10.1155/2013/423205
Abstract: Objectives. The aim of this naturalistic study was to investigate whether treatment with clozapine and other atypical antipsychotics for at least 2 years was associated with a reduction in psychotic and depressive symptoms and an improvement in chronic schizophrenia patients’ awareness of their illness. Methods. Twenty-three adult outpatients (15 men and 8 women) treated with clozapine and 23 patients (16 men and 7 women) treated with other atypical antipsychotics were included in the study. Psychotic symptoms were evaluated using the Positive and Negative Syndrome Scale (PANSS), depressive symptoms were assessed with the Calgary Depression Scale for Schizophrenia (CDSS), and insight was assessed with the Scale to Assess Unawareness of Mental Disorder (SUMD). Results. The sample as a whole had a significant reduction in positive, negative, and general symptoms, whereas the reduction in depression was significant only for patients with CDSS scores of 5 and higher at the baseline. At the follow-up, patients treated with other atypical antipsychotics reported a greater reduction in depression than patients treated with clozapine, but not when limiting the analyses to those with clinically relevant depression. Conclusions. Atypical antipsychotics may be effective in reducing psychotic and depressive symptoms and in improving insight in patients with chronic schizophrenia, with no differences in the profiles of efficacy between compounds. 1. Introduction Schizophrenia is a serious and disabling mental disorder usually associated with a decline in social and occupational functioning, and deficits in communication, control of behavior, the ability to feel pleasure, will, and initiative. The disease affects approximately 1% of the world’s population, or around 1–12 adults in every 1,000, mostly in the 15–35 year-old group [1–3]. Yearly incidence is 16–40 cases per 100,000 according to the ICD-9 criteria and 7–14 cases per 100,000 using more restrictive criteria [4, 5]. The risk of developing schizophrenia during a lifetime is around 0.7% (95% confidence interval (CI): 0.3%–2.0%) [3]. The longitudinal course of schizophrenia is characterized by recurrent episodes of illness, periods of complete or partial remission, and often chronicity. Schizophrenia is linked to functional and social disability, it impacts the patients’ ability to engage in productive work and social relationships, and it is associated with a reduced life expectancy as a result of accidents, high comorbidity with medical conditions, and suicide [6–17]. Furthermore, depression in schizophrenic
Lancashire: a Land of Witches in Shakespeare’s Time
Luca Baratta
Journal of Early Modern Studies , 2013,
Abstract: This article focuses on the connection between Shakespeare’s Macbeth and the famous English witch trial which took place in Lancashire in 1612. The judicial proceeding was recorded by a clerk of the court, who went by the name of Thomas Potts, whose reportage of the events was inconsistent and unstable, as I attempt to point out. In so doing, I underline the reasons – political, religious and opportunistic – that possibly motivated his behaviour, highly criticisable by modern standards.
Ritualità e rischio nella vita quotidiana
Carlo Baratta
m@gm@ , 2005,
Abstract: La vita quotidiana à caratterizzata dall'incertezza, occorre imparare a vivere perché le abitudini, che favoriscono modi di vivere costanti, sono sempre più frammentarie e liquide. Informazioni ed eventi si sovrappongono e non sempre sono tra loro coerenti. L'individuo contemporaneo deve sviluppare quello che Bateson chiama deuterroapprendimento, deve costruirsi un metodo per evitare azioni velleitarie che portano all'angoscia.
Le identità deboli e la perdita del Padre nella società occidentale
Carlo Baratta
m@gm@ , 2004,
Abstract: Scopo di questo contributo è analizzare le problematiche della formazione di identità nella società contemporanea, problematiche trasversali, che riguardano la costruzione del sé, le reti di relazioni che si determinano in una società complessa e i contesti anche virtuali che in essa si costruiscono. Identità caratterizzate da alta volatilità e perciò deboli, identità che non danno senso alla vita, perché dipendono da stili di vita temporanei, difficilmente sequenziabili. L'articolo propone una rilettura di Pareto e di Gehlen, testi di Risè e Prandstraller hanno permesso di definire meglio la dimensione qualitativa delle identità deboli. L'affievolirsi della figura paterna, nella società contemporanea, sia essa postindustriale, postmoderna, neomoderna è una ragione evidente della formazione di identità deboli.
Scuola Filosofia Cittadinanza nel pensiero di Gramsci: Esercizi di lettura Escola, filosofia e cidadania no pensamento de Gramsci: exercícios de leitura School, philosophy and citizenship in Gramsci's thought: reading exercises
Giorgio Baratta
Pro-Posi??es , 2010, DOI: 10.1590/s0103-73072010000100003
Abstract:
Nidia R. Areces. 2007. Estado y frontera en el Paraguay. Concepción durante el gobierno del Dr. Francia. Asunción: CEADUC Centro de Estudios Antropológicos, Universidad Católica "Nuestra Se ora de la Asunción". 496 p
Victoria Baratta
Mundo agrario , 2009,
Abstract:
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