oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 521 )

2018 ( 706 )

2017 ( 696 )

2016 ( 969 )

Custom range...

Search Results: 1 - 10 of 402253 matches for " Marinho Valeska M. "
All listed articles are free for downloading (OA Articles)
Page 1 /402253
Display every page Item
Doen a de Alzheimer e espectroscopia por ressonancia magnética do hipocampo
Engelhardt Eliasz,Moreira Denise M.,Laks Jerson,Marinho Valeska M.
Arquivos de Neuro-Psiquiatria , 2001,
Abstract: OBJETIVOS: Obten o de dados do espectro de metabolitos por ressonancia magnética da forma o hipocampal no idoso normal e com doen a de Alzheimer (DA). MéTODO: Os indivíduos foram pareados por idade, sendo 20 na amostra normal, CDR=0 e 40 com DA 3 CDR=1 e 2. Utilizou-se aparelho Signa Horizon LX-GE, 1.5T, 1H-ERM com aplicativo automatizado PROBE/SV, VOI: hc (direito e esquerdo); voxel único (2x2x2cm); TR 1500ms/TE 50ms; PRESS; metabolitos: N-acetilaspartato (Naa), colina (Cho), creatina (Cr), mio-inositol (mI). RESULTADOS: Os presentes dados se referem aos quocientes de Naa, Cho e mI, com Cr tomada como referência e rela o mI/Naa. O estudo mostrou o Naa reduzido, o mI e a rela o mI/Naa aumentados e os resultados em rela o à Cho foram variados. Os resultados da amostra global dos pacientes com DA em compara o à média ± dp da amostra normal foram significativos para Naa, mI e mI/Naa (p<0,01). A precis o, tomando os valores de modo individual das duas amostras, mostrou sensibilidade, especificidade e valor preditivo positivo satisfatórios. CONCLUS O: Os presentes resultados podem ser usados como ferramenta útil para detectar altera es patológicas no hipocampo de pacientes com DA, permitindo diagnóstico de maior precis o e mais precoce da doen a.
Doen?a de Alzheimer e espectroscopia por ressonancia magnética do hipocampo
Engelhardt, Eliasz;Moreira, Denise M.;Laks, Jerson;Marinho, Valeska M.;Rozenthal, Marcia;Oliveira Jr, Amarino C.;
Arquivos de Neuro-Psiquiatria , 2001, DOI: 10.1590/S0004-282X2001000600006
Abstract: objective: acquisition of data of magnetic resonance metabolite spectrum of the hippocampal formation (hippocampus-hc) in the elderly, normal and with alzheimer's disease (ad). method: subjects matched for age: a. normal sample (n=20), cdr=0, and b. ad sample (n=40), cdr 1 and 2. technique: signa horizon lx-ge, 1.5t, 1h-mrs with automated software probe/sv, voi: hc (right and left); single voxel (2x2x2cm); tr 1500ms/te 50ms; press; metabolites: n-acetylaspartate (naa), choline (cho), creatine (cr), myo-inositol (mi). results: the present data relate to the ratios of naa, cho and mi, with cr taken as reference, and the mi/naa ratio. the study showed reduction of naa, increase of mi and of the mi/naa ratio, and not consistent results for cho. the results of the whole sample of ad patients compared to the pooled normal mean ± sd were significant for naa, mi and mi/naa (p<0.01). accuracy in relation to the individual values of both samples showed satisfactory levels of sensitivity, specificity and positive predictive value. conclusion: the present results can be used as a helpful tool to detect pathologic changes of the hippocampus in ad, and allowing greater accuracy and an earlier diagnosis of this disease.
Efficacy and safety of risperidone oral solution in agitation associated with dementia in the elderly
Laks, Jerson;Engelhardt, Eliasz;Marinho, Valeska;Rozenthal, Marcia;Souza, Fernando de Castro e;Bacaltchuk, Josué;Stoppe Jr., Alberto;Ferreira, R.C.R.;Bottino, Cassio;Scalco, M?nica;
Arquivos de Neuro-Psiquiatria , 2001, DOI: 10.1590/S0004-282X2001000600005
Abstract: background: behavioral and psychological symptoms in dementia (bpsd) contribute to caregiver burden and institutionalization of elderly. neuroleptics are prescribed to control agitation. side effects of typical neuroleptics are harmful, making atypical neuroleptics an indication. objectives: to evaluate efficacy and tolerability of risperidone oral solution (ros) given once daily to demented elderly outpatients with bpsd (agitation). method: patients (n=26), 76.35±8.63 years, diagnostic and statistical manual of mental disorders 4th ed. (dsm-iv) criteria for dementia. rso was given, starting dose of 0.25 mg and increments of 0.25 mg every week. mini-mental state examination (mmse) assessed cognitive status, behavioral and emotional activities manifested in dementia (beam-d) and clinical global impression (cgi) measured bpsd, extrapiramidal symptom rating scale (esrs) evaluated extrapyramidal symptoms. cardiovascular side effects were evaluated clinically. results: there was a 26% reduction in agitation and no cardiovascular side effects in the range from 1.0 to 1.25 mg. side effects were more prevalent above 2.5 mg. conclusion: risperidone oral solution improved agitation with good tolerability from 0.5 to 1.25 mg. a single dose with increments of 0.25 mg may be more acceptable to patients and caregivers.
Sintomas neuropsiquiátricos nas demências: relato preliminar de uma avalia??o prospectiva em um ambulatório do Brasil
Vega, úrsula Maria;Marinho, Valeska;Engelhardt, Eliasz;Laks, Jerson;
Arquivos de Neuro-Psiquiatria , 2007, DOI: 10.1590/S0004-282X2007000300026
Abstract: this study aimed to evaluate the behavioral and psychological symptoms in dementia (bpsd) and to correlate the level of the functional dependence, cognitive decline and neuropsychiatric symptoms in outpatients. in this prospective study, 35 elderly with dementia (dsm-iv) were evaluated over the course of one year with the mini-mental state examination (mmse), clinical dementia rating scale (cdr), neuropsychiatric inventory (npi) and functional activities questionnaire (faq). spearman correlation was used to compare cognitive, functional and behavioral symptoms in the first and last visits. the psychotic versus non-psychotic subgroups were compared by means of cognitive and functional performance. the mann-whitney test was used for the comparison. the mmse scores declined and the npi scores showed better results at endpoint. prevalence of depressive symptoms was 58.8%, agitation 55.9%, and delusion 41.2%. significant correlations were found for functional and mmse scores, years of formal education and npi, but not for duration of disease. psychotic symptoms had negative effects on daily activities of outpatients and were associated with functional decline.
Pharmacological treatment of frontotemporal lobar degeneration: systematic review
Portugal, Maria da Glória;Marinho, Valeska;Laks, Jerson;
Revista Brasileira de Psiquiatria , 2011, DOI: 10.1590/S1516-44462011000100016
Abstract: objective: to identify the therapeutic options available for treatment of cognitive and behavioral symptoms in frontotemporal lobar degeneration. method: systematic review using the descriptors "frontotemporal lobar degeneration" or "frontotemporal dementia" or "fronto-temporal dementia" or "fronto-temporal degeneration" or "pick's disease" or "pick's atrophy" or "semantic dementia" or "progressive aphasia" and "pharmacotherapy" or "treatment" or "efficacy" or "effects" or "management" was performed in the medline and lilacs databases. selection criteria: quality a - randomized clinical trials. quality b - open studies or reports of six or more cases. quality c - reports of five or fewer cases. two reviewers independently assessed the clinical studies. information collected included diagnostic criteria used, sample size, duration, efficacy and tolerability measures used and results obtained. results: from the 532 studies found, 29 complied with the inclusion criteria. all studies worked with a small sample, had short duration of treatment and used non-uniform measures in evaluating efficacy and tolerability. studies showed disparate results with respect to behavior and cognition. conclusion: there is still little, and poor, evidence available for treatment of frontotemporal lobar degeneration and studies with better methodological background are needed.
Efficacy and safety of risperidone oral solution in agitation associated with dementia in the elderly
Laks Jerson,Engelhardt Eliasz,Marinho Valeska,Rozenthal Marcia
Arquivos de Neuro-Psiquiatria , 2001,
Abstract: BACKGROUND: Behavioral and psychological symptoms in dementia (BPSD) contribute to caregiver burden and institutionalization of elderly. Neuroleptics are prescribed to control agitation. Side effects of typical neuroleptics are harmful, making atypical neuroleptics an indication. OBJECTIVES: To evaluate efficacy and tolerability of risperidone oral solution (ROS) given once daily to demented elderly outpatients with BPSD (agitation). METHOD: Patients (n=26), 76.35±8.63 years, Diagnostic and Statistical Manual of Mental Disorders 4th ed. (DSM-IV) criteria for dementia. RSO was given, starting dose of 0.25 mg and increments of 0.25 mg every week. Mini-Mental State Examination (MMSE) assessed cognitive status, Behavioral and Emotional Activities Manifested in Dementia (BEAM-D) and Clinical Global Impression (CGI) measured BPSD, Extrapiramidal Symptom Rating Scale (ESRS) evaluated extrapyramidal symptoms. Cardiovascular side effects were evaluated clinically. RESULTS: There was a 26% reduction in agitation and no cardiovascular side effects in the range from 1.0 to 1.25 mg. Side effects were more prevalent above 2.5 mg. CONCLUSION: Risperidone oral solution improved agitation with good tolerability from 0.5 to 1.25 mg. A single dose with increments of 0.25 mg may be more acceptable to patients and caregivers.
Tobacco use among the elderly: a systematic review and meta-analysis
Marinho, Valeska;Laks, Jerson;Coutinho, Evandro Silva Freire;Blay, Sergio Luís;
Cadernos de Saúde Pública , 2010, DOI: 10.1590/S0102-311X2010001200002
Abstract: the aim of this study was to combine the results of identified surveys on the prevalence of tobacco use in old age to estimate world prevalence of tobacco use and possible factors related to such behavior among the elderly. the literature search included electronic databases such as medline, lilacs, and biological abstracts, hand-searching of specialist journals and cited reference searches. the combined global prevalence was estimated using the random effects model. the total number of elderly subjects included in all surveys was 140,058, with data available from all the continents. overall prevalence of tobacco use was 13% in both genders (22% male and 8% female). the prevalence rates were heterogeneous among surveys and were associated with smoking definition, questionnaire application, and country economic status. few epidemiological studies assessed tobacco use among the elderly. a higher prevalence rate of tobacco use in males who live in higher income countries could be found, although additional evidence regarding elderly samples is still required.
A new species of Moenkhausia Eigenmann (Characiformes: Characidae) from the rio Xingu basin, Brazil
Marinho, Manoela M. F.;
Neotropical Ichthyology , 2010, DOI: 10.1590/S1679-62252010000300011
Abstract: a new species of moenkhausia from the upper rio xingu basin is described. moenkhausia eurystaenia is distinguished from all congeners, except m. heikoi and m. phaeonota, by the presence of a dark, broad longitudinal stripe from the opercle to the end of caudal peduncle. the new species is distinguished from m. heikoi mainly by having 18-21 branched anal-fin rays (vs. 24-26) and the absence of a round blotch at the end of the caudal peduncle (vs. present). moenkhausia eurystaenia can be distinguished from m. phaeonota mainly by the anterior portion of longitudinal band darker at horizontal septum (vs. darker below horizontal septum), the deep dark pigmentation along horizontal septum extending anteriorly up to humeral region (vs. extending up to vertical through pelvic-fin origin), number of vertebrae 34 (vs. 36-37), and others additional measurements.
O dem?nio nos "paraísos artificiais": considera??es sobre as políticas de comunica??o para a saúde relacionadas ao consumo de drogas
Marinho, M?nica Benfica;
Interface - Comunica??o, Saúde, Educa??o , 2005, DOI: 10.1590/S1414-32832005000200010
Abstract: the phenomenon of drug consumption in contemporary society is the theme of broad discussions. regarding healthcare communication policies in brazil, there is a blatant lack of regard for the constitutive dimensions of this phenomenon. as a result, conduct related to the prevention of drug consumption involves the said consumption in marginal significances that, far from fostering a sensibility to behavioral change, generate prejudice against and segregation of the user. this can be seen in the prevention campaigns - whether governmental or otherwise - against the use of legal and illegal drugs and that are part of these communication policies. therefore, an understanding of how the consumption phenomenon reaches certain significances and how the campaigns express these significances is what this article proposes to achieve.
Entre o funcional e o lúdico: a camisinha nas campanhas de preven??o da aids
Marinho, M?nica Benfica;
Interface - Comunica??o, Saúde, Educa??o , 2000, DOI: 10.1590/S1414-32832000000100008
Abstract: the starting point for this study is the idea that there are obstacles to the use of condoms. it discusses some of these impediments, namely, the parallel meaning of condoms as something associated with infidelity and promiscuity. these interpretations were analyzed relative to the behavioral model that governs sexual practice and human reproduction, i.e., monogamy. this paper emphasizes that campaigns designed to encourage the use of condoms may be more effective if they dilute the "negative" image connected with these meanings, by associating condoms, for instance, with pleasure and safety, through playful and relaxed advertising.
Page 1 /402253
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.