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Search Results: 1 - 10 of 6003 matches for " Marina Taus "
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Inflammatory Bowel Diseases: What Do We Still Need to Investigate?  [PDF]
Marina Taus, Debora Busni, Daniele Fumelli, Arianna Paci, Giulia Nicolai, Albano Nicolai
Open Journal of Gastroenterology (OJGas) , 2015, DOI: 10.4236/ojgas.2015.510024
Abstract: Inflammatory bowel disease (IBD) including Crohn (CD) and ulcerative colitis (UC), is intestinal disorders with an unknown specific etiology. Many factors are involved in the pathogenesis: genetic, environment, nutrition, immunity and intestinal dysbiosis. In the present work, we review the most important trigger mechanisms involved in IBD, with a particular regard to the role of microbiota and fecal mass transplantation as a new therapeutic approach, that even if it can be considered safe and effective, data are necessary regarding all procedures not yet standardized and timing of treatment.
Coeliac Disease: Gluten Free Diet and… What Else?  [PDF]
Marina Taus, Elsa Veronica Mignini, Daniele Fumelli, Debora Busni, Giulia Nicolai, Carla Carletti, Albano Nicolai
Open Journal of Gastroenterology (OJGas) , 2016, DOI: 10.4236/ojgas.2016.611035
Abstract: Coeliac Disease (CD) is a permanent gluten intolerance, whose pathogenesis involves multiple factors including genetics and environment. CD has different representations and non-specific symptoms such as diarrhea, bloating, pain, flatulence and constipation may sometimes be misleading. Once diagnosed of CD, patients must adhere to Gluten Free Diet, which consists in the lifelong avoidance of gluten containing foods and of those naturally gluten free but at risk of contamination. This dietary approach is considered the only therapy in order to avoid symptoms exacerbation and to reduce the digestive mucosa inflammation, which has been related to higher risks of lymphoproliferative malignancy and other immunological disorders. However, being on a Gluten Free Diet is not as resolving as it may seem since it has several criticalities. First of all, excluding gluten means limiting food variety so that coeliac patients may have unbalanced intake of several nutrients and develop clinical or subclinical deficiencies. This can be due to scarce attention to qualitative and quantitative composition of diets and poor information about gluten-containing foods, which only patient-tailored dietetic protocol and long-term follow-up can achieve. Secondly, Gluten Free Diet may not result in complete remission of mucosal damage or in resolution of symptoms. Unintentional contamination of gluten or poor adherence to diet are the main culprits of the incomplete mucosal healing but other triggers may be involved. Recent research has focused on the role of FODMAPs in changing gut microbiota and on the improvement of Irritable Bowel Syndrome (IBS) symptoms after their dietary avoidance or reduction. Since CD and IBS may share many clinical presentations, further studies are needed to evaluate if a subgroup of CD patients whose symptoms are not improved by Gluten Free Diet could benefit from a new therapeutic approach consisting in both gluten/wheat and FODMAPs avoidance.
Bilder der Endoskopie: Teilnekrose des Colons sigmoideum und oralen Rektums nach Embolisierung einer Rektalblutung bei Prostatakarzinom
Hauser H,Mischinger HJ,Taus J
Journal für Gastroenterologische und Hepatologische Erkrankungen , 2004,
Abstract:
Cut Elimination in Multifocused Linear Logic
Taus Brock-Nannestad,Nicolas Guenot
Computer Science , 2015, DOI: 10.4204/EPTCS.176.3
Abstract: We study cut elimination for a multifocused variant of full linear logic in the sequent calculus. The multifocused normal form of proofs yields problems that do not appear in a standard focused system, related to the constraints in grouping rule instances in focusing phases. We show that cut elimination can be performed in a sensible way even though the proof requires some specific lemmas to deal with multifocusing phases, and discuss the difficulties arising with cut elimination when considering normal forms of proofs in linear logic.
EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia
álvaro Taus,Flavio Zuccarino,Carlos Trampal,Edurne Arriola
Case Reports in Pulmonology , 2012, DOI: 10.1155/2012/257827
Abstract: PET-CT scan has demonstrated to be very effective in lung cancer diagnosis and staging, but lung cancer has multiple ways of presentation, which can lead to an error in diagnosis imaging and a delay on the beginning of specific treatment. We present a case of a 77-year-old man with an initial PET-CT scan showing high 18F-FDG intake, suggesting a bilateral pneumonia, who was finally diagnosed of an EGFR-mutant lung adenocarcinoma. EGFR-activating mutation allowed us to start treatment with the oral tyrosin kinase inhibitor Gefitinib, obtaining a rapid and sustained response. Histological confirmation of imaging findings is always necessary to avoid diagnostic errors.
Malignant Catarrhal Fever: Understanding Molecular Diagnostics in Context of Epidemiology
Hong Li,Cristina W. Cunha,Naomi S. Taus
International Journal of Molecular Sciences , 2011, DOI: 10.3390/ijms12106881
Abstract: Malignant catarrhal fever (MCF) is a frequently fatal disease, primarily of ruminants, caused by a group of gammaherpesviruses. Due to complexities of pathogenesis and epidemiology in various species, which are either clinically-susceptible or reservoir hosts, veterinary clinicians face significant challenges in laboratory diagnostics. The recent development of specific assays for viral DNA and antibodies has expanded and improved the inventory of laboratory tests and opened new opportunities for use of MCF diagnostics. Issues related to understanding and implementing appropriate assays for specific diagnostic needs must be addressed in order to take advantage of molecular diagnostics in the laboratory.
EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia
álvaro Taus,Flavio Zuccarino,Carlos Trampal,Edurne Arriola
Case Reports in Pulmonology , 2012, DOI: 10.1155/2012/257827
Abstract: PET-CT scan has demonstrated to be very effective in lung cancer diagnosis and staging, but lung cancer has multiple ways of presentation, which can lead to an error in diagnosis imaging and a delay on the beginning of specific treatment. We present a case of a 77-year-old man with an initial PET-CT scan showing high 18F-FDG intake, suggesting a bilateral pneumonia, who was finally diagnosed of an EGFR-mutant lung adenocarcinoma. EGFR-activating mutation allowed us to start treatment with the oral tyrosin kinase inhibitor Gefitinib, obtaining a rapid and sustained response. Histological confirmation of imaging findings is always necessary to avoid diagnostic errors. 1. Introduction Staging of nonsmall-cell lung cancer was one of the first approved indications for the use of positron emission tomography (PET) [1]. Since 2001, combined PET and computed tomography (PET-CT scan) has rapidly replaced stand-alone PET and has become a key tool in the staging of lung cancer [2]. Although [ 1 8 F ] Fluoro-2-deoxy-D-glucose (18F-FDG) has high sensitivity for cancerous conditions, there are benign processes that result in abnormal accumulation of and false positive images. These false positive results are due to conditions where 18F-FDG accumulation occurs in metabolically active tissue that is not cancerous, such as infection or inflammatory processes [3]. 2. Case Report We present a 77-year-old man, with no history of smoking, admitted to the emergency room with a 2 month history of malaise, shortness of breath, and weight loss. His medical history involved controlled heart failure, arterial hypertension, hypercholesterolemia, and obstructive sleep apnea syndrome. Blood count, liver, and renal functions were normal. Chest X-ray showed areas of consolidation in both lung bases, predominantly left. A CT-scan of the chest demonstrated diffuse bilateral ground glass nodules, ill-defined areas of pulmonary opacities with “crazy-paving” pattern in right lower and middle lobes, and extensive air-space consolidation in left lung (Figures 1(a), 1(b), 1(c), and 1(d)). These findings suggested inflammatory or infectious process as first choice, being less likely neoplasic aetiology or organizing pneumonia. Figure 1: CT-scan of the chest shows bilateral nonsolid pulmonary nodules (a and b: black arrows) and ill-defined areas of pulmonary opacities with “crazy-paving” pattern in right lower and middle lobes (c, d: black asterisk). In left lung extensive air-space consolidation is present (b, c, and d: red asterisk). Follow-up CT-scan realized 8 months later after Gefitinib
Psychopathology of Joseph Stalin  [PDF]
Marina Stal
Psychology (PSYCH) , 2013, DOI: 10.4236/psych.2013.49A1001
Abstract:

Between 1928 and 1953, Joseph Stalin was the undisputed totalitarian dictator of the former Soviet Union whose “reign of fear” continues to maintain its egregious reputation. An examination of Stalin’s documented behaviors attempts to evaluate any signs of psychopathology in accordance with DSM-IV-TR criteria. Evidence of a troubled upbringing, depression, paranoia, and alcohol abuse suggests psychopathology as an implicating factor behind Stalin’s actions. Utilizing such a perspective may allow for future distinctions of individuals deemed responsible for horrendous atrocities.

The Role of Group Size and Correlated Project Outcomes in Group Lending  [PDF]
Marina Markheim
Theoretical Economics Letters (TEL) , 2017, DOI: 10.4236/tel.2017.75080
Abstract: This paper analyzes contract efficiency with regard to correlated project realization and the size of the borrowers in group lending. Firstly, I show that under the standard assumption of independent project payoffs, the expected group cost of default decreases with group size. Secondly, I show that small groups can also optimize group efficiency if individual payoffs and credit risks are correlated. The results outline that social cost minimization occurs due to a common interest in forming optimal borrower groups between lenders and borrowers.
On a New Index Aimed at Comparing Risks  [PDF]
Marina Resta, Maria Erminia Marina
Journal of Mathematical Finance (JMF) , 2015, DOI: 10.4236/jmf.2015.52011
Abstract: This paper fits into the research stream started by Aumann and Serrano (2008) with their index RAS, and introduces a new index of riskiness called Iθ. In particular, our intuition moves from the observation that the RAS index is defined over the set of gambles whose expected value of losses is lower than the one of gains. We then restrict the attention on investment opportunities in a proper relation with a benchmark value \"\" and we build the index Iθ. The mathematical features of the new index are discussed in deepest detail, providing evidence that Iθ can be used by the investor in comparing risks: θ plays the role of a threshold value such that once fixed in the range (0,1] , Iθ suggests to take into consideration a gamble (an investment, an asset) g only if the ratio between the expected value of its losses and the expected value of its gains is lower than such θ. Moreover, Iθ nests RAS as special case when θ = 1, and it satisfies both homogeneity and duality properties. In the light of these features, Iθ seems to satisfy the common need among practitioners for flexible index of riskiness.
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