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Search Results: 1 - 10 of 25 matches for " Marilyne Rosselle "
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Teacher Module in an Assistance Tool - Adaptating a device to a teaching context and and teacher's preferences
Marilyne Rosselle
Computer Science , 2012,
Abstract: This communication presents the genesis and the implementation of a teacher module, which is included in an Assistance Tool (AT). The teacher module is based on a teacher model for which we did a thorough analysis of the state of the art. The aim of the AT is to help a teacher to design pedagogical devices. Teachers can formulate their needs (assistance in the design) and the AT can relieve them from repetitive tasks related to the deployment of a teaching device (assistance in the deployment).
Using USB Keys to Promote Mobile Learning
Marilyne Rosselle,Dominique Leclet,Bénédicte Talon
International Journal of Interactive Mobile Technologies (iJIM) , 2009, DOI: 10.3991/ijim.v3s1.843
Abstract: M-learning (i.e. mobile learning) is a field of e-learning that provides learners learning environments using mobile technology. In this context, learning can take place anywhere and anytime, in open and distance learning. Depending on the type of technology it may be done through software called nomadic (i.e. prepared to mobility). Among these technologies, there are those composed of digital interfaces and with autonomy of treatment: Smartphone, PDA, calculator and even mp3 key. In this article we propose to take into account storage devices as mobile technologies. Our focus was on the USB key. We present a procedure to test whether a learning environment embarked on a USB key can be described as nomadic or not. This procedure has been tested on a sample of three ILE (Interactive Learning Environment. This approach has allowed us to define criteria of nomadism, criteria which were then included in the design of a synchronous Weblog on USB key.
Reusing Available (educational) Software developed by CAL (Computer Assisted Learning) Researchers?
Marilyne ROSSELLE,Marie-Noelle BESSAGNET,Thibault CARRON
STICEF , 2005,
Abstract: This article tackles the problem of educational software re-use in research purpose. Theses pieces of software are prototypes or environments developed by other research teams. After having analyzed the requirements to integrate educational software in order to build an experiment, we argue around an integration architecture proposition. Our requirement analysis ensues on a presentation of the various possible dimensions of integration. Towards these dimensions, we present five case studies stemming from the French community. Based on theses case studies, handling interoperability and integration issues, we illustrate the set of problems collectively studied within the “Action Spécifique Plateformes” group. We conclude by proposing a guide of good practices for integration.
Determination and Quantification of Trace Elements, by ICP_MS, in the River Water of Sarzhal and Akzhar Villages  [PDF]
Zhanibek Yessimbekov, Duyssembaev Sergazy, Dilraba Iminova, Eleonora Okushanova, Marilyne Stuart
Journal of Environmental Protection (JEP) , 2013, DOI: 10.4236/jep.2013.410122
Abstract:

In the present study, trace elements present in the river waters of Sarzhal and Akzhar region were measured using inductively coupled plasma mass spectrometry (ICP-MS). The reason for monitoring trace elements at those two locations is to verify water quality. The village of Sarzhal is situated in an area that has been affected by weapon testing and continues to receive inputs of contaminants (including radionuclides). The concentrations of trace elements in the river water of Sarzhal and Akzhar villages were generally found to be within allowable levels. However, the concentrations of Na 251.56 mg/l, Cr 3.26 μg/l, P 64.56 μg/l and Se 18.162 μg/l in the river of Akzhar were found to be higher than the maximum allowable concentrations (MAC). In Sarzhal, the level of Al 6.66 mg/l, Cr 5.04 μg/l and P 13.44 μg/l exceeded the MAC values.

SOS fran ais : Conception et évaluation d’un didacticiel d’aide à la rédaction interactif
Rymenams Sara,Verlinde Serge,Marx Steven,Rosselle Mieke
SHS Web of Conferences , 2012, DOI: 10.1051/shsconf/20120100182
Abstract: L’objectif de la présente contribution est double. D’une part, nous présentons un nouveau didacticiel d’aide à la rédaction destiné à des apprenants de fran ais langue étrangère ou seconde, SOS fran ais, que nous situons par rapport aux correcteurs orthographiques et grammaticaux existants. SOS fran ais fournit un contr le de texte axé sur les principaux items orthographiques, grammaticaux et lexicaux réputés difficiles et sources d’erreurs fréquentes et récurrentes. Il se caractérise par un feedback très développé destiné à aider les apprenants à développer leurs compétences langagières. Une description grammaticale est également intégrée. Un deuxième volet de notre contribution est consacré à une étude d’efficacité. Nous y posons trois questions de recherche, portant sur l’efficacité de SOS fran ais lors de la correction de textes, sur l’impact que peut avoir un tel outil sur la ma trise du fran ais à court et à moyen terme et sur la corrélation entre l’efficacité de l’aide et le type d’item grammatical. Nous avons pour cela mis en place une étude auprès de quelque 200 étudiants de première année universitaire. Dans la contribution, nous présentons la méthodologie suivie et les tout premiers résultats de cette étude, qui montrent l’intérêt de ce type d’outil tout en confirmant les constatations faites dans d’autres études quant à la difficulté de corriger les problèmes de grammaire.
Faecal and Urinary Incontinence after Multimodality Treatment of Rectal Cancer
Marilyne M Lange,Cornelis J. H van de Velde
PLOS Medicine , 2008, DOI: 10.1371/journal.pmed.0050202
Abstract:
A Tethered Bilayer Assembled on Top of Immobilized Calmodulin to Mimic Cellular Compartmentalization
Claire Rossi,Samah Doumiati,Clarine Lazzarelli,Marilyne Davi,Fetta Meddar,Daniel Ladant,Jo?l Chopineau
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0019101
Abstract: Biomimetic membrane models tethered on solid supports are important tools for membrane protein biochemistry and biotechnology. The supported membrane systems described up to now are composed of a lipid bilayer tethered or not to a surface separating two compartments: a ”trans” side, one to a few nanometer thick, located between the supporting surface and the membrane; and a “cis” side, above the synthetic membrane, exposed to the bulk medium. We describe here a novel biomimetic design composed of a tethered bilayer membrane that is assembled over a surface derivatized with a specific intracellular protein marker. This multilayered biomimetic assembly exhibits the fundamental characteristics of an authentic biological membrane in creating a continuous yet fluid phospholipidic barrier between two distinct compartments: a “cis” side corresponding to the extracellular milieu and a “trans” side marked by a key cytosolic signaling protein, calmodulin.
Recombination Every Day: Abundant Recombination in a Virus during a Single Multi-Cellular Host Infection
Remy Froissart,Denis Roze,Marilyne Uzest,Lionel Galibert,Stephane Blanc,Yannis Michalakis
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.0030089
Abstract: Viral recombination can dramatically impact evolution and epidemiology. In viruses, the recombination rate depends on the frequency of genetic exchange between different viral genomes within an infected host cell and on the frequency at which such co-infections occur. While the recombination rate has been recently evaluated in experimentally co-infected cell cultures for several viruses, direct quantification at the most biologically significant level, that of a host infection, is still lacking. This study fills this gap using the cauliflower mosaic virus as a model. We distributed four neutral markers along the viral genome, and co-inoculated host plants with marker-containing and wild-type viruses. The frequency of recombinant genomes was evaluated 21 d post-inoculation. On average, over 50% of viral genomes recovered after a single host infection were recombinants, clearly indicating that recombination is very frequent in this virus. Estimates of the recombination rate show that all regions of the genome are equally affected by this process. Assuming that ten viral replication cycles occurred during our experiment—based on data on the timing of coat protein detection—the per base and replication cycle recombination rate was on the order of 2 × 10?5 to 4 × 10?5. This first determination of a virus recombination rate during a single multi-cellular host infection indicates that recombination is very frequent in the everyday life of this virus.
Human pluripotent stem cells: From biology to cell therapy
Jean-Marie Ramirez,Qiang Bai,Marilyne Dijon-Grinand,Said Assou
World Journal of Stem Cells , 2010,
Abstract: Human pluripotent stem cells (PSCs), encompassing embryonic stem cells and induced pluripotent stem cells, proliferate extensively and differentiate into virtually any desired cell type. PSCs endow regenerative medicine with an unlimited source of replacement cells suitable for human therapy. Several hurdles must be carefully addressed in PSC research before these theoretical possibilities are translated into clinical applications. These obstacles are: (1) cell proliferation; (2) cell differentiation; (3) genetic integrity; (4) allogenicity; and (5) ethical issues. We discuss these issues and underline the fact that the answers to these questions lie in a better understanding of the biology of PSCs. To contribute to this aim, we have developed a free online expression atlas, Amazonia!, that displays for each human gene a virtual northern blot for PSC samples and adult tissues (http://www.amazonia.transcriptome.eu).
Recombination Every Day: Abundant Recombination in a Virus during a Single Multi-Cellular Host Infection
Remy Froissart,Denis Roze,Marilyne Uzest,Lionel Galibert,Stephane Blanc,Yannis Michalakis
PLOS Biology , 2005, DOI: 10.1371/journal.pbio.0030089
Abstract: Viral recombination can dramatically impact evolution and epidemiology. In viruses, the recombination rate depends on the frequency of genetic exchange between different viral genomes within an infected host cell and on the frequency at which such co-infections occur. While the recombination rate has been recently evaluated in experimentally co-infected cell cultures for several viruses, direct quantification at the most biologically significant level, that of a host infection, is still lacking. This study fills this gap using the cauliflower mosaic virus as a model. We distributed four neutral markers along the viral genome, and co-inoculated host plants with marker-containing and wild-type viruses. The frequency of recombinant genomes was evaluated 21 d post-inoculation. On average, over 50% of viral genomes recovered after a single host infection were recombinants, clearly indicating that recombination is very frequent in this virus. Estimates of the recombination rate show that all regions of the genome are equally affected by this process. Assuming that ten viral replication cycles occurred during our experiment—based on data on the timing of coat protein detection—the per base and replication cycle recombination rate was on the order of 2 × 10?5 to 4 × 10?5. This first determination of a virus recombination rate during a single multi-cellular host infection indicates that recombination is very frequent in the everyday life of this virus.
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