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Search Results: 1 - 10 of 71666 matches for " Maria Sole Basso "
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Ulcerative Colitis and Acute Thrombocytopenia in a Pediatric Patient: A Case Report and Review of the Literature  [PDF]
Bronislava Papadatou, Fiammetta Bracci, Daniela Knafelz, Antonella Diamanti, Maria Sole Basso, Fabio Panetta, Filippo Torroni, Valerio Nobili, Giuliano Torre
Health (Health) , 2014, DOI: 10.4236/health.2014.612184
Abstract: We report the case of a 14-year-old boy affected by ulcerative colitis (UC) and acute thrombocytopenic purpura (ITP) with simultaneous onset. UC diagnosis was based on symptoms, endoscopy and histology findings. ITP diagnosis was based on the normal bone marrow megakaryocyte count, the presence of platelet associated IgG and the absence of splenomegaly. Medical treatments including high doses of steroids, intravenous immunoglobulins were ineffective on ITP course, while UC course was mild for several months after the onset. When colonic inflammation became untractable not responsive at steroids and immunosuppressive agents, colectomy resolved both pathologies.
Celiac Disease and Overweight in Children: An Update
Antonella Diamanti,Teresa Capriati,Maria Sole Basso,Fabio Panetta,Vincenzo Maria Di Ciommo Laurora,Francesca Bellucci,Fernanda Cristofori,Ruggiero Francavilla
Nutrients , 2014, DOI: 10.3390/nu6010207
Abstract: The clinical presentation of celiac disease in children is very variable and differs with age. The prevalence of atypical presentations of celiac disease has increased over the past 2 decades. Several studies in adults and children with celiac disease indicate that obesity/overweight at disease onset is not unusual. In addition, there is a trend towards the development of overweight/obesity in celiac patients who strictly comply with a gluten-free diet. However, the pathogenesis and clinical implications of the coexistence of classic malabsorption (e.g., celiac disease) and overweight/obesity remain unclear. This review investigated the causes and main clinical factors associated with overweight/obesity at the diagnosis of celiac disease and clarified whether gluten withdrawal affects the current trends of the nutritional status of celiac disease patients.
De coniugio leprosorum: antiche questioni di bio-diritto
Maria Sole Testuzza
Forum Historiae Iuris , 2012,
Abstract: The topic of coniugium leprosorum in the thought of theologians and canonists, from the Middle Ages through the Early Modern Period, is articulated into a variety of relevant issues. Besides its effects on sponsalia, the serious disease casts doubt on the validity of the marriage and, between theory and practice, on how to deal with spouses in case of lepra superveniens. Furthermore, the disease involves the so-called carnale debitum. In the presence of a serious disease, what are the limits of jus in corpus? Is it allowed the fulfilment of the obligation at the expense of one’s own life and for the benefit of (spiritual) health of someone else, or ad bonum commune? How to consider the behaviour of one who denies sexual performance for fear of procreating offspring afflicted with severe anomaly? Consequently, can be life considered a damage to the child? This essay deals with reasoning that, in a prolific dialogue between morality and law, were used to reach solutions to questions that look close to our postmodern bioethical and legal dilemmas.
Use of radiation in strains of Saccharomyces cerevisiae: A new technique for industrial applications  [PDF]
Rafael O. Andrette, Jo?o D. T. Arruda-Neto, Thiago O. Basso, Luiz Carlos Basso, Erika Cavalcante-Silva, Maria C. Bittencourt-Oliveira, Godofredo C. Genofre
Advances in Bioscience and Biotechnology (ABB) , 2013, DOI: 10.4236/abb.2013.43045
During the industrial fermentation process in the production of fuel ethanol, yeasts are subject to several stressing conditions. The survival and the permanence of strains introduced in the process correlate with the capability of these yeasts in resisting to physical and chemical stresses, as well as their recovering ability to compete with contaminating micro-organisms commonly present in this industrial process. We aim at the selection of Saccharomyces cere visiae strains having this capability and ability. In this sense, cultivations of strains with industrial interest were irradiated with gammas ray at a wide dose interval. Growing curves for the strains were analyzed by means of their relative growth, a new concept here introduced, which allows a better understanding of the growing and recovering processes following radiative stress. It was found that gamma radiation could be used as an alternative method to quantify growing capabilities of S. cerevisiae strains under stressing conditions. It was also shown that this radiological method could be utilized as an additional procedure to select best robust industrial strains. This radiological method simplifies traditional analysis of strain viability, by avoiding the great number of necessary and consecutive fermentation assays.
The value of some Corsican sub-populations for genetic association studies
Veronica Latini, Gabriella Sole, Laurent Varesi, Giuseppe Vona, Maria Ristaldi
BMC Medical Genetics , 2008, DOI: 10.1186/1471-2350-9-73
Abstract: Samples were analyzed using seven dinucleotide microsatellite markers on chromosome Xq13-21: DXS983, DXS986, DXS8092, DXS8082, DXS1225, DXS8037 and DXS995 spanning approximately 4.0 cM (13.3 Mb). We have also investigated the distribution of the DXS1225-DXS8082 haplotype which has been recently proposed as a good marker of population genetic history due to its low recombination rate.the results obtained indicate a decrease of LD on the island from the central mountainous toward the coastal sub-populations. In addition the analysis of the DXS1225-DXS8082 haplotype revealed: 1) the presence of a particular haplotype with high frequency; 2) the derivation from a common genetic pool of the sub-populations examined in the present study.These results indicate the Corsican sub-populations useful for the fine mapping of genes contributing to complex diseases.Isolates have been of considerable use in genetic studies aimed at identifying mutations underlying rare diseases [1]. Moreover, isolated populations also afford several advantages in unrevealing the genetics of complex diseases [2,3]. The identification of genes involved in the pathogenesis of multifactorial diseases would contribute towards a better understanding of the physiopathology of these conditions. Furthermore, the prevention and development of new therapeutic approaches would be significantly enhanced.Association studies are critically dependent on the extent of LD. Several reports have underlined how Linkage Disequilibrium (LD) is more extended in founder populations [4]. LD extended over large regions increases the power of association studies since the number of markers to be analyzed is at least 30% less than in outbred populations [4].Genetic homogeneity found in isolated populations is a great advantage in the identification of large genomic regions containing the disease-associated locus, while fine mapping could require recently expanded population.The aim of this paper is an evaluation of some Corsic
Downregulation of Immunoglobulin-Like Transcript-4 (ILT4) in Patients with Psoriatic Arthritis
Alberto Bergamini, Maria Sole Chimenti, Eleonora Baffari, Maria Domenica Guarino, Gianfranco Gigliucci, Carlo Perricone, Roberto Perricone
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0092018
Abstract: Objective The immunoglobulin-like transcript-4 (ILT4) is an inhibitory receptor that modulates the activity of innate immune agents. We determined the expression of ILT4 and analysed the relationship with the expression of costimulatory proteins and tumor necrosis factor-α (TNF-α) production in monocytes from patients with psoriatic arthritis (PsA) starting anti-TNF treatment. Methods Peripheral blood monocytes from 15 healthy controls and from 16 patients with PsA were activated in vitro by CD40 ligand (CD40L) and analyzed for ILT4, CD40, CD80 and CD86 expression, and spontaneous lipopolysaccharide (LPS)-induced TNF-α production by flow cytometry, before and after treatment with adalimumab. Results The percentage of ILT4-negative monocytes was greater in PsA patients compared to controls and negatively correlated with DAS44. Normal monocytes treated with sera of PsA patients showed a reduced expression of ILT4 compared with monocytes exposed to sera from controls. CD40, CD80 and CD86 expression was higher in patients compared to controls. Both spontaneous and LPS-induced TNF-α production was restricted to ILT4-negative monocytes and was greater in PsA patients compared to controls. Finally, twelve weeks-treatment with adalimumab resulted in a significant increase of ILT4 expression and a decrease of costimulatory molecules expression in PsA patients, compared to pre-therapy levels. Conclusions These data support the possibility that changes in the immunophenotype of monocytes play a role in the pathogenesis of PSA. Thus, modulation of the expression of ILT4 may represent an enticing new therapeutic target.
Efeito da reeduca??o postural global no alinhamento corporal e nas condi??es clínicas de indivíduos com disfun??o temporomandibular associada a desvios posturais
Basso, Débora;Corrêa, Eliane;Silva, Ana Maria da;
Fisioterapia e Pesquisa , 2010, DOI: 10.1590/S1809-29502010000100012
Abstract: the purpose of this study was to assess the effects of the technique of global postural re-education (gpr) on body alignment and clinical status of individuals with temporomandibular disorder (tmd) associated to postural deviations. twenty individuals with both tmd and postural deviations confirmed by physical examination were assessed, before and after treatment, by the research diagnostic criteria for temporomandibular disorders (rdc/tmd) and as to body angle measures, by digital photogrammetry. treatment consisted of 10 weekly, 45-minute gpr sessions. results after treatment show higher predominance of myogenic dysfunction (rather than joint or disc ones) and significant orofacial pain intensity relief; the percentage of individuals without depression raised from10% to 35%; the percentage of individuals with physical symptoms classified as normal (excluding pain items) raised from 30 to 55%. a statistically significant improvement was found in most body structures angle measures, except at lower limb frontal angles and at the right leg/foot angle. head alignment and measures of cervical and lumbar lordosis, having normal values before treatment, did not change. hence the gpr treatment may be said to have brought significant relief of tmd physical and psychological symptoms, as well as improvement in body alignment and symmetry.
Morphological development of Alfagraze cultivar and Crioula alfalfa populations selected at the seedling stage
Favero, Daniela;Scheffer-Basso, Simone Meredith;Carneiro, Cerci Maria;
Revista Brasileira de Zootecnia , 2009, DOI: 10.1590/S1516-35982009000400003
Abstract: the objective of this study was to compare two populations of crioula alfalfa cultivars, selected by the length of the seedling second internode (crioula-li, long internode = 2.5 cm; crioula-si, short internode = 1.5 cm) with alfagraze cultivar in order to verify the seedling morphology value for the selection of more prostrate plants. the plants were grown individually in pots in a semi-protected environment and harvested at 74, 104, 134, 164, 194 and 224 days. crioula populations varied in terms of height, leaf area, root volume, dry matter yield, and the crioula-li population outnumbered that of crioula-si. for height, length of internode and primary stem, alfagraze (45.1 cm, 2.1 cm and 16.7 cm) was similar to crioula-si (37.6 cm, 2.3 cm and 18.2 cm); however, the leaf area (2.028 cm2) and dry matter yield (20.3 g) did not differ from those of crioula-li (2.021 cm2, 21 g). the alfagraze cultivar surpassed the crioula population in terms of procumbency, crown diameter and crown stem number. at the flowering stage, the crioula-li cultivar had total stem number (61/plant) higher than alfagraze (47/plant) and crioula-si (41/plant) cultivars. the length of the seedling internode is a promising marker for the selection of alfalfa, being a predictive factor for plant height, stem number, root volume and leaf area, and can be useful in the alfalfa breeding.
Aspectos morfofisiológicos e bromatológicos de Paspalum plicatulum
Scheffer-Basso, Simone Meredith;Gallo, Milena Maria;
Revista Brasileira de Zootecnia , 2008, DOI: 10.1590/S1516-35982008001000007
Abstract: this work aimed to evaluate the forage value of a brown-seed grass (paspalum plicatulum) population, considering bromatological aspects and dry matter accumulation. plants were obtained from tussocks and they were established in a weed-free area 80 cm apart from each other. the experimental design was completely randomized and treatments consisted of plant age after establishment characterized by days (d) and degree-days (dd) accumulated above 0oc. harvests were performed at ground level in late-spring (27 d, 587 dd), mid-summer (68 d, 1534 dd), mid-fall (149 d, 3311 dd), and mid-winter (226 d, 4527 dd). brown-seed grass showed 11-22% of crude protein, 39-46% of acid detergent fiber and 55-66% of neutral detergent fiber, good tolerance to summer drought, and produced green dry matter during spring, summer and fall. growth stopped when the temperatures dropped below 15oc. morphologically the population showed a high tillering potential (105/plant), compact tussocks (circumference = 53 cm), basal sprouting, and erect growth.
Valor dos achados clínicos e da avalia??o funcional pulmonar pré-operatórios como preditores das complica??es pulmonares pós-operatórias
Silva, Denise Rossato;Gazzana, Marcelo Basso;Knorst, Marli Maria;
Revista da Associa??o Médica Brasileira , 2010, DOI: 10.1590/S0104-42302010000500016
Abstract: objective: to assess the relationship between clinical and preoperative pulmonary functional evaluation and occurrence of postoperative pulmonary complications. methods: we conducted a retrospective cohort study with patients submitted to pulmonary functional evaluation over a period of 5 years. we collected clinical, demographic and spirometric data, also those related to surgical procedures and postoperative pulmonary complications. results: medical records of 521 patients were evaluated. mean age was 59.5 ± 14 years, 65.8% were male, and 93.4% were white. the mean fev1, was 76.6 ± 24.6% of the predicted. clinical comorbidities were present in 73.5% of all patients (copd in 29.8%). the most common surgical sites were thorax (n=122; 23.4%) and upper abdomen (n=117; 22.5%). postoperative pulmonary complications occurred in 99 patients (19.0%), with respiratory insufficiency as the most common (4.6%). forty three patients (8.3%) died. the rates of pulmonary complications were higher after thoracic (28.9%), cardiac (28%) and upper abdomen surgery (24.3%) (p<0.0001). most patients with pulmonary complications (66.7%) were classified as asa iii and iv (p<0.01), and in 70.2% time of anesthesia was > 3.5 hours (p<0.0001). median lenght of hospital stay was statistically different between patients with and without pulmonary complications (23.5 [15.8-34] days vs. 10 [6-18] days; p<0.001). patients who never smoked had fewer complications than those with current or past smoking history (p=0.04). we did not find significant association between postoperative pulmonary complications and presence of copd, fev1, and body mass index (p>0.05). conclusion: the most important factors associated with postoperative pulmonary complications were surgical site, time of anesthesia, and asa classification.
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