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Search Results: 1 - 10 of 82624 matches for " Maria Isabel Rodriguez "
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Non-contraceptive applications of the levonorgestrel intrauterine system
Maria Isabel Rodriguez, Philip D Darney
International Journal of Women's Health , 2010, DOI: http://dx.doi.org/10.2147/IJWH.S6344
Abstract: n-contraceptive applications of the levonorgestrel intrauterine system Review (4617) Total Article Views Authors: Maria Isabel Rodriguez, Philip D Darney Published Date April 2010 Volume 2010:2 Pages 63 - 68 DOI: http://dx.doi.org/10.2147/IJWH.S6344 Maria Isabel Rodriguez, Philip D Darney Department of Obstetrics, Gynecology, and Reproductive Sciences, San Francisco General Hospital and Bixby Center for Global Reproductive Health, University of California, San Francisco, CA, USA Abstract: Intrauterine progestins have many important current and potential gynecologic applications. This article describes the evidence for use of intrauterine progestin for common gynecologic conditions beyond its important role in contraception. The pharmacology of and selection criteria for use of the levonorgestrel intrauterine device is discussed, and the evidence for use of intrauterine progestin delivery for menorrhagia, endometriosis management, uterine fibroids, adenomyosis and endometrial hyperplasia is reviewed.
Non-contraceptive applications of the levonorgestrel intrauterine system
Maria Isabel Rodriguez,Philip D Darney
International Journal of Women's Health , 2010,
Abstract: Maria Isabel Rodriguez, Philip D DarneyDepartment of Obstetrics, Gynecology, and Reproductive Sciences, San Francisco General Hospital and Bixby Center for Global Reproductive Health, University of California, San Francisco, CA, USAAbstract: Intrauterine progestins have many important current and potential gynecologic applications. This article describes the evidence for use of intrauterine progestin for common gynecologic conditions beyond its important role in contraception. The pharmacology of and selection criteria for use of the levonorgestrel intrauterine device is discussed, and the evidence for use of intrauterine progestin delivery for menorrhagia, endometriosis management, uterine fibroids, adenomyosis and endometrial hyperplasia is reviewed.Keywords: intrauterine progestin, levonorgestrel, contraceptive
Drosophila TIEG Is a Modulator of Different Signalling Pathways Involved in Wing Patterning and Cell Proliferation
Isabel Rodriguez
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0018418
Abstract: Acquisition of a final shape and size during organ development requires a regulated program of growth and patterning controlled by a complex genetic network of signalling molecules that must be coordinated to provide positional information to each cell within the corresponding organ or tissue. The mechanism by which all these signals are coordinated to yield a final response is not well understood. Here, I have characterized the Drosophila ortholog of the human TGF-β Inducible Early Gene 1 (dTIEG). TIEG are zinc-finger proteins that belong to the Krüppel-like factor (KLF) family and were initially identified in human osteoblasts and pancreatic tumor cells for the ability to enhance TGF-β response. Using the developing wing of Drosophila as “in vivo” model, the dTIEG function has been studied in the control of cell proliferation and patterning. These results show that dTIEG can modulate Dpp signalling. Furthermore, dTIEG also regulates the activity of JAK/STAT pathway suggesting a conserved role of TIEG proteins as positive regulators of TGF-β signalling and as mediators of the crosstalk between signalling pathways acting in a same cellular context.
Trajetória do enfermeiro em um hospital universitário em quatro décadas: pressupostos de inova??o de seu papel gerencial
Trevizan, Maria Auxiliadora;Mendes, Isabel Amélia Costa;Godoy, Simone de;Alves, Leila Maria Marchi;Rodriguez, Eliana Llapa;
Revista Brasileira de Enfermagem , 2005, DOI: 10.1590/S0034-71672005000200014
Abstract: among the challenges faced by brazilian nursing, the situation of indefiniteness about the nursing role in the hospital context demands a vigorous determination by nursing leaders. hospital institutions aim at specific objectives, without satisfactorily considering the needs, values, potential and diversities of different professionals. objective: carry out a comparative data analysis and extract points of congruence, delimitations and possibilities that allow us to point out directions with a view to more efficient actions. the methodology covered a secondary analysis of five classical studies about nurses' functions, developed in brazilian literature throughout four decades. this analysis resulted in the discussion and proposal of flexible and humanizing presuppositions to guide the role of nurses in hospital care practice.
Evaluación de dos estrategias de educación nutricional vía radio en Guadalajara, México
Cabrera-Pivaral, Carlos Enrique;Ninel Mayari, Centeno Lopez;Arredondo Trueba, Jose Miguel;Gonzalez Perez, Guillermo Julian;Vega Lopez, Maria Guadalupe;Valadez Figueroa, Isabel;Aldrete Rodriguez, Maria Guadalupe;
Cadernos de Saúde Pública , 2002, DOI: 10.1590/S0102-311X2002000500021
Abstract: modifying knowledge and attitudes through persuasive communication in health via radio has produced encouraging results for public health planners. this study's objective was to measure the effect of an educational strategy on knowledge and attitudes towards nutrition in two marginalized communities in guadalajara, mexico. two communities were randomly selected. in each community a group of individuals was invited to be exposed to radio broadcasts. using a coded and structured instrument, knowledge and attitudes towards the contents of nutritional education for health were measured before and after the intervention in both groups. group a (n = 37) was organized and exposed to the dynamics of the radio forum throughout the 4 months during which the project lasted. group b (n = 33) was not organized, and listened to the radio program according to its own cultural dynamics. median knowledge and attitudes (ka) for group a was 56.8 in the pre-test and 74.1 in the post-test (w: p = -0.05). in group b the ka results were 53.0 and 59.2, respectively (w: p = -0.05). the results emphasize the advantages of the radio forum as a health communications strategy for human nutrition.
Atención Primaria en Salud en Paraguay: panorámica y perspectiva
Dullak,Roberto; Rodriguez-Riveros,María Isabel; Bursztyn,Ivani; Cabral-Bejarano,Maria Stella; Ruoti,Monica; Paredes,Maria Elsa; Wildberger,Carmen; Molinas,Faustina;
Ciência & Saúde Coletiva , 2011, DOI: 10.1590/S1413-81232011000600024
Abstract: this paper presents an overview of primary health care (phc) in paraguay, as part of a multicentric study, seeking to identify the possibilities of phc as a factor for reorganizing the health system. the methodology adopts the comprehensive phc concept, and takes into consideration the system's segmentation, formed by the public sector of the ministry of health and welfare, social security, a not-for-profit private sector, a private for-profit sector and a mixed sector. the study analyzes 5 dimensions: stewardship, financing, resources, integration/continuity, intersectorality/participation, through reviewing data from the literature and official documents, and key informant interviews (experts, decision-makers, professionals and civil society). advances in health policy legislation since the 1990, with gratuity for all age groups, have been observed. public spending on health is among the lowest in latin america. phc is provided through different vertical programs, with poor coordination and articulation, though a recent political shift prioritizes the progressive implementation of family health teams. in conclusion, phc can contribute to improve health, equity and participation.
Epidemiological Clinical Features and Evolution of Gastroduodenal Ulcer Bleeding in a Tertiary Care Hospital in Spain, during the Last Seven Years
Eugenia Lauret,Jesús Herrero,Lorena Blanco,Olegario Casta?o,Maria Rodriguez,Isabel Pérez,Verónica Alvarez,Adolfo Suárez,Luis Rodrigo
Gastroenterology Research and Practice , 2013, DOI: 10.1155/2013/584540
Abstract: Background. Gastroduodenal ulcer bleeding is a common medical emergency. The aim of this study was to analyze the characteristics of bleeding episodes and to identify changes in the clinical trends over seven years. Methods. Retrospective observational clinical study on a cohort of 272 consecutive adult patients with peptic ulcer bleeding, during the 2006–2012 period. Results. Mean annual admission rate was 12.8 per 100.000 inhabitants. Men were predominant (71%), with a mean age of 66.6 years. Comorbidities were present in 131 cases (48.2%) and 156 patients (57.4%) had received ulcerogenic drugs. Duodenal ulcer was the commonest location (61%). Endoscopic therapy was necessary in 183 cases (67.3%) and rebleeding occurred in 30 patients (11%). Overall mortality rate was 5.5%, with a significant association with the presence of comorbidities ( ). There were no differences in trends of annual hospitalization, clinical features at presentation, and outcomes during this 7-years period. Conclusions. Annual hospitalization rates and prognosis of peptic ulcer bleeding have remained unchanged in the study period. This may be due to the fact that the effect of improved approach on this condition is probably counteracted by risk factors such as older age, severe comorbidities, and ulcerogenic drugs consumption, which have also remained stable over recent years. 1. Introduction Peptic ulcer bleeding remains a major clinical problem in the emergency setting, in Western countries. During the last decades, mortality rates from this gastrointestinal disorder have been reported to be stable, ranging between 5% and 15% worldwide [1, 2]. Despite increased knowledge about this condition, the use of improved diagnostics tools, the great advances in endoscopic therapy, and the routine use of ulcer treatment with proton pump inhibitors (PPIs) as well as eradication therapies against Helicobacter pylori, the published data on the changes in incidence and mortality for ulcer hemorrhage have been divergent [3–6]. In the nationwide population-based time-trend studies, a decline in general hospitalization rates was described over time, except among the elderly [4, 5]. By contrast, in regional population-based studies, the incidence of peptic ulcer bleeding was found unchanged [6]. The growing elderly population with presence of comorbidities and the gradual increase in prescription number of low-dose aspirin (ASA), nonsteroidal anti-inflammatory drugs (NSAID), and other antiplatelet or anticoagulant drugs have been recognized as some of the reasons for the expected changes on
Overview of Five-Years of Experience Performing Non-Invasive Fetal Sex Assessment in Maternal Blood
Sara Perlado-Marina,Ana Bustamante-Aragones,Laura Horcajada,Maria Jose Trujillo-Tiebas,Isabel Lorda-Sanchez,Marta Ruiz Ramos,Javier Plaza,Marta Rodriguez de Alba
Diagnostics , 2013, DOI: 10.3390/diagnostics3020283
Abstract: Since the discovery of the presence of fetal DNA in maternal blood, non-invasive fetal sex determination has been the test most widely translated into clinical practice. To date there is no agreement between the different laboratories performing such tests in relation to which is the best protocol. As a consequence there are almost as many protocols as laboratories offering the service, using different methodologies and thus obtaining different diagnostic accuracies. By the end of 2007, after a validation study performed in 316 maternal samples collected between the 5th and 12th week of gestation, the fetal sex determination was incorporated into clinical practice in our Service. The test is performed in the first trimester of pregnancy, and it is offered as part of the genetic counseling process for couples at risk of X-linked disorders. As a general rule and in order to avoid misdiagnosis, two samples at different gestational ages are tested per patient. The analysis is performed by the study of the SRY gene by RT-PCR. Two hundred and twenty six pregnancies have been tested so far in these 5 years. Neither false positives nor false negatives diagnoses have been registered, thus giving a diagnostic accuracy of 100%.
On the black hole species (by means of natural selection)
Maria J. Rodriguez
Physics , 2010,
Abstract: Recently our understanding of black holes in D-spacetime dimensions, as solutions of the Einstein equation, has advanced greatly. Besides the well established spherical black hole we have now explicitly found other species of topologies of the event horizons. Whether in asymptotically flat, AntideSitter or deSitter spaces, the different species are really non-unique when D > 4. An example of this are the black rings. Another issue in higher dimensions that is not fully understood is the struggle for existence of regular black hole solutions. However, we managed to observe a selection rule for regular solutions of thin black rings: they have to be balanced i.e. in vacuum, a neutral asymptotically flat black ring incorporates a balance between the centrifugal repulsion and the tension. The equilibrium condition seems to be equivalent to the condition to guarantee regularity on the geometry of the black ring solution. We will review the tree of species of black holes and present new results on exotic black holes with charges.
El modelo actual de ciudad fronteriza mexicana. Urbanismos yuxtapuestos y herméticos
Eloy Méndez,Isabel Rodriguez,Liliana Lopez
Bifurcaciones , 2005,
Abstract: Diversos modelos urbanísticos confluyen en la frontera México-Estados Unidos. El modelo fronterizo tiende a configurarse y diferenciarse como un híbrido cultural complejo a partir de los dos modelos nacionales. Partiendo de la hipótesis de que estas ciudades están marcadas por el efecto de frontera, exploramos los rasgos que advierten la posible emergencia de este modelo peculiar. La abrupta separación territorial jurídica es permeable a los flujos socioeconómicos y aún demográficos, pero también a nuevas formas de control disciplinario sobre el territorio expresadas en la proliferación de barreras físicas en el interior del tejido urbano. El proyecto de ciudad en construcción privilegia del lado mexicano el urbanismo defensivo, que abordamos en el entorno construido como recurso de identidad. Los nuevos consumos de espacio físico en la ciudad enfatizan el aspecto lúdico de los innumerables segmentos materiales que la integran, emergiendo cada uno a la manera de atractivo consumible autónomo. El escenario resultante tiende entonces a constituirse en su totalidad con bienes adquiribles, donde los promotores inmobiliarios ofertan la vivienda –el espacio de consumo por excelencia- validos de técnicas de marketing inductoras del encuentro feliz del residente con el hábitat acorde a los más caros valores de su identidad, y por lo mismo, vueltos imprescindibles. El espacio ha de consumirse tras la cualificación material, el tratamiento simbólico y el acotamiento parcelario derivado de capacidades adquisitivas y expectativas de estilo de vida, una identidad prefabricada.
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