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Search Results: 1 - 10 of 13390 matches for " Margarita; Porto Q "
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CARCINOMA SARCOMATOIDE MONOFáSICO DE MAMA: CASO CLíNICO
Carballo N,Elba; Pérez P,Alberto; Buján,Vanesa; Guldrís N,Eva María; Gil A,Margarita; Porto Q,Magdalena;
Revista chilena de obstetricia y ginecología , 2011, DOI: 10.4067/S0717-75262011000100008
Abstract: sarcomatoid carcinoma of the breast is a histological variant of metaplastic carcinoma, composed predominantly of spindle cells. we report a case of a tumor in a woman of 54 years old, which suggested a clinical and radiological malignant tumor. finally the histology and immunohistochemistry confirmed the diagnostic of monophasic sarcomatoid carcinoma. in this variant of sarcomatoid carcinoma, is not possible to identify a clear epithelial component, creating problems of differential diagnosis between sarcomas and other mesenchymal damages. the immunohistochemical demonstration of epithelial nature of the spindle cells was essential for the diagnosis.
Diagnóstico precoce de anormalidades no desenvolvimento em prematuros: instrumentos de avalia??o
Santos, Rosana S.;Araújo, Alexandra P. Q. C.;Porto, Maria Amelia S.;
Jornal de Pediatria , 2008, DOI: 10.1590/S0021-75572008000400003
Abstract: objective:to review the literature regarding screening psychomotor tests for the early identification of developmental problems. sources: a search on scielo, pubmed and google scholar was performed using the terms "prematurity," "developmental delay," "cerebral palsy," "early diagnosis" and "evaluation tests." summary of the findings:a total of 455 references were listed, and 174 studies were selected for this review based on title, relevance, and abstract. only original and electronically available material, from 1985 forward, with information on design, applicability, and psychometric properties of those tests was included. conclusions: screening tests are important to speed the beginning of treatment measures in order to allow for better developmental outcome. among the many tests that can be employed for this purpose, the denver ii and the alberta infant motor scale are the most often used in brazilian studies. the movement assessment of infants is starting to be used in our country. two other tests are recommended in the literature due to their high sensibility and specificity: the test of infant motor performance and the general movements.
Determinación de diclofenaco de sodio por cromatografía líquida de alta resolución en un colirio al 0,1 % Determination of Diclofenac sodium by high-performance liquid chromatography in 0,1 % eyedrops
Caridad Margarita García Pe?a,Diana Pereda Rodríguez,Ania González Cortezón,Yanet Montes de Oca Porto
Revista Cubana de Farmacia , 2009,
Abstract: El diclofenaco de sodio es un medicamento que se indica para los tratamientos posoperatorios de la inflamación del segmento anterior del ojo, la inhibición de la miosis pre y posoperatoria de cataratas, el tratamiento sintomático de las conjuntivitis crónicas no infecciosas y de la inflamación ocular, del dolor ocular y fotofobia poscirugía refractiva. En este trabajo se desarrolló y validó un método analítico por cromatografía líquida de alta resolución, para el control de la calidad y los estudios de estabilidad del diclofenaco de sodio 0,1 %, colirio. El método se basó en la separación del principio activo a través una columna cromatográfica Lichrospher 100 RP-8 endcapped (5 μm) (250 x 4 mm), con detección UV a 254 nm, para lo cual se empleó una fase móvil compuesta por solución de hidrógeno fosfato de sodio a pH 2,5:metanol, en proporción 34:60. La curva de calibración se realizó en el intervalo de 60 al 140 %, donde fue lineal con un coeficiente de correlación igual a 0,9995; la prueba estadística para el intercepto y la pendiente se consideró no significativa. Se obtuvo un recobrado del 100,25 % en el intervalo de concentraciones estudiados y las pruebas de Cochran′(G) y Student′s (t) resultaron no significativas. El coeficiente de variación en el estudio de la repetibilidad fue igual a 0,39 % para las 6 réplicas ensayadas, mientras que en los análisis de la precisión intermedia las pruebas de Fischer y Student fueron no significativas. El método analítico resultó lineal, preciso, específico y exacto en el intervalo de concentraciones estudiadas. Diclofenac sodium is a drug prescribed in eye anterior segment inflammation postoperative treatments, preoperative and postoperative cataract miosis inhibition, symptomatic treatment of non-infectious chronic conjunctivitis, of ocular inflammation, of ocular pain, and of refractory postsurgical photophobia. In present paper we developed and validated an analytical method by high-performance liquid chromatography to quality control, and stability studies of Diclofenac sodium of 1 % eyedrops. Method was based on active principle separation through endcapped 1 00RP-8 Lichrospher chromatographic column (5 μ) (250 x 4 mm) using UV detection to 254 nm, thus using a mobile phase including sodium a solution of hydrogen phosphate to a 2.5 pH: methanol in a 34:60 ratio. Calibration curve was plotted during the interval of 60 to 140 % where it was linear with a correlation coefficient equal to 0.9995; statistic test for interception and slope was considered as non-significant. We achieved a recovery rate of 100.25 %
Crescimento de cultivares de mel?o amarelo irrigadas com água salina
Alencar, Renato D.;Porto Filho, Francisco de Q.;Medeiros, José F. de;Holanda, José S. de;Porto, Vania C. N.;Ferreira Neto, Miguel;
Revista Brasileira de Engenharia Agrícola e Ambiental , 2003, DOI: 10.1590/S1415-43662003000200006
Abstract: the effect of five irrigation water salinity levels (n: 1.51, 2.79, 3.93, 5.15 and 7,22 ds m-1), on initial development of two yellow melon cultivars (gold mine and af646) was studied. the trial was conducted under field conditions in an orchard belonging to department of phytotechnic - esam, at mossoró in the state of rio grande do norte, brazil, during the period of november 4 to december 12, 1998. plastic pots with 9 l capacity filled with alfisol soil (horizon ap1) were used. experimental design was a completely randomized block in a factorial scheme, with three replications. shoot dry matter, leaf area, mean soil salinity and final soil salinity were evaluated through variance and regression analysis. salinity tolerance was similar for gold mine and af646, with a loss of 6.8% of shoot dry matter for unit increase of electrical conductivity of irrigation water. a similar behavior was observed for leaf area. irrigation water salinity induced linear effect on mean soil salinity and quadratic effect on final soil salinity.
Caracteriza??o hidráulica do microaspersor Rondo, da Plastro
Holanda Filho, Roberto S.F. de;Porto Filho, Francisco de Q.;Miranda, Neyton de O.;Medeiros, José F. de;
Revista Brasileira de Engenharia Agrícola e Ambiental , 2001, DOI: 10.1590/S1415-43662001000100004
Abstract: in order to assess the hydraulic characteristics of the microsprinkler rondo 50 l h-1, with blue nozzle, manufactured by plastro, tests were carried out in the hydraulic laboratory of the escola superior de agricultura de mossoró (esam). estimates were made for discharge pressure head equation, manufacturer?s coefficient of variation, profile of distribution, uniformity of water application and water application uniformity with overlap. the manufacture?s coefficient of variation is classified as excellent and the characteristic equation is q = 3.4312 h0.516, characterizing a turbulent flow. the microsplinker has a throw radius of a 3.3 m. the best emitter spacing with overlap found was 1.2 x 1.2 m, although for spacing up to 3.6 x 3.6 m the application uniformity was above 80%.
Feminización y masculinización en los estudios de maestro y educación física en Galicia
Benxamín Porto Porto
Revista de Investigación en Educación , 2009,
Abstract: El objetivo es analizar la distribución de las matrículas por sexo en las especialidades de Maestro y licenciaturas en Ciencias de la Actividad Física y Deporte de las universidades gallegas. La hipótesis es que los valores tradicionales de género y el desinterés femenino por el deporte se traducen en elecciones diferenciadas de los estudios universitarios relacionados con la docencia y el deporte. La metodología analiza fuentes estadísticas de las matrículas universitarias por sexo. Los resultados muestran que la feminización afecta en general a los estudios de Maestro, mientras que la masculinización afecta a los estudios sobre actividad física y deporte. Se concluye que la eficaz socialización en los valores tradicionales de género y el desinterés de las mujeres por el fenómeno deportivo explicarían la elección diferencial.
Excretion study of clomiphene in human urine: evaluation of endogenous steroids profile after multiple oral doses
Martínez Brito, Dayamín;Oca Porto, Rodny Montes de;Correa Vidal, Margarita Teresa;Socarrás Ojeda, Roberto;Rosado Pérez, Arístides;
Journal of the Brazilian Chemical Society , 2010, DOI: 10.1590/S0103-50532010001200008
Abstract: selective estrogen receptor modulators are classified as prohibited substances according to the list of forbidden substances in sports by the international olympic committee and the world anti-doping agency. clomiphene (2-(4-(2-chloro-1,2-diphenylethenyl)phenoxy)-n,n-diethyl-ethanamine) is mainly used for the treatment of infertility because it acts inducing the ovulation by direct stimulations of gonadotropic activity. clomiphene citrate (50 mg per day for 5 days) was orally administered to one healthy female with infertility treatment. urine samples were collected up to 1 week post-dose. a new metabolite using gas chromatography-mass spectrometry has been identified in addition to the hydroxyclomiphene previously reported. it has been proposed as hydroxymethoxyclomiphene. monitorization of this metabolite have been proposed for doping control keeping in mind that the main metabolite hydroxyclomiphene is excreted relatively faster than hydroxymethoxyclomiphene from urine. on the other hand, significant changes on steroids profile after multiple doses were observed. the main variation was observed on absolute concentration of oestrogens and their ratios.
Validación del método analítico para el control de la calidad y estudio de estabilidad de fenilefrina 10 % colirio
Monteagudo Licea,Raiza; García Pe?a,Caridad Margarita; Botet García,Martha; Troche Concepción,Yenilen; Montes de Oca Porto,Yanet;
Revista Cubana de Farmacia , 2010,
Abstract: phenylephrine is used like mydiatric in eye examinations and other ophthalmic procedures. it is used as vasoconstrictor with local anesthetic agents. in present paper a high ressolution liquid chromatography analytical method was validated to quality control and stability studies of 10 % phenylephrine (eyedrops). mathod was based in separation of active principle through a lichrosorb ro-18 (5 μm) (250 x 4 mm) chromatography column with uv detection at 280 nm using a mobile phase composed by a non-gasified mixture of methanol distilled water (1:1) with 1.1 g of 1-sodium octane-sulphonate by liter adjusted to ph 3,0 with phosphoric acid at a flow speed of 1.0 ml/min. analytical method was linear, accuracy, specific and exact in the interval of study concentrations.
Desarrollo y validación de un método analítico para el control de calidad y estabilidad de fenilefrina 10 % colirio y tropicamida 1 %
García Pe?a,Caridad Margarita; Botet García,Martha; Troche Concepción,Yenilen; Zú?iga Dedorite,Georgy; Montes de Oca Porto,Yanet;
Revista Cubana de Farmacia , 2011,
Abstract: an analytical high-performance liquid chromatography method was developed and validated applicable to quality control and to stability study of 10 % phenylephrine plus eyedrops 1 % tropicamide. to quantify simultaneously both active principles in the finished product, separation was carried out through a lichrosorb rp-18 (15 μm) (260 x 4 mm) column chromatography, with ultraviolet detection at 253 nm using the mobile phase composed of methanol: distilled water (1:1), with 1.1 g of sodium 1-octasulfanate by litre and ph fitted to 3.0 with phosphoric acid and the quantification of this front to a reference sample using the external standard method. the analytical method developed was linear, precise, specific and accurate in the rank of study concentrations, established for the quality control and stability study of the finished product since there were not analytical methods designed for these aims.
Dise?o de una formulación de fenilefrina 10 % y tropicamida 1 % colirio: eyedrops
Zu?iga Dedorite,Georgy Armando; García Pe?a,Caridad Margarita; Botet García,Martha; Troche Concepción,Yenilen; Montes de Oca Porto,Yanet; Baró Román,Gerardo;
Revista Cubana de Farmacia , 2010,
Abstract: the 10 % phenylephrine and 1 % tropicamide eyedrops is used in medical practice as antihistaminic, analgesic, mydiatric and cycloplegic. the aim of present paper was to develop a 10% phenylephrine and 1 % tropicamide formula fulfilling the quality specifications established by manufacturer physically, chemically and microbiologically stable with the performing of a design and pre-formula studies. also, we studied the quality specifications of selected formula, the product stability and its expiry time. an analytical method was developed and validated to quality control and stability study of the finished product by high-performance liquid chromatography. analytical results of accelerated stability study and by shelf life using 3 batches of product at pilot scale. eyedrops was physically, chemically and microbiologically stable when it was bottling in low density polyethylene flasks during 12 months of storage at room temperature.
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