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Search Results: 1 - 10 of 297562 matches for " Margaretha J. Combrink "
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Incidence, severity and management of cancer chemotherapy related oral mucositis in Eastern Cape and Western Cape
Johanna E. Maree,Margaretha J. Combrink,Tanya de Lange,Andrea S. Toerien
Health SA Gesondheid , 2012,
Abstract: This study explored the incidence, duration and severity of oral mucositis in patients receiving chemotherapy in the Eastern and Western Cape, how this symptom was managed and whether the patients considered the management to be effective. An exploratory, contextual, quantitative survey was conducted. The sampling method was convenience. One hundred and sixty patients were recruited, with 106, (66.3%) participating. Data were collected by means of self-reports, using a self-administered questionnaire. Oral mucositis was a common problem, with 71.7% (n = 76) reporting to have had mucositis. Pain was not effectively managed, as 69.8% (n = 53) of respondents experienced pain whilst only 17.1% (n = 13) reported to have used analgesics. More than half of the respondents used prescribed mouth and throat preparations, whilst 28.9% (n = 22) used non-prescribed self-care measures including potentially harmful products. A significant difference was found between using non-prescribed self-care measures and the duration of oral mucositis (χ2 = 0.81; p = 0.01). The reported grade of mucositis did not influence the use of non-prescribed self-care measures, whilst the more pain patients experienced the less inclined they were to use these measures. The management of oral mucositis remains a challenge. Failure to palliate this distressing symptom can lead to the use of potentially harmful self-care measures. Die studie het die insidensie, tydsduur en intensiteit van orale mukositis in Oos en Wes Kaapse pasi nte wat kankerchemoterapie ontvang verken asook hoe hierdie simptoom hanteer is en die sukses hiervan volgens die pasi nte. ‘n Kwantitatiewe, ekploratiewe, kontekstuele opname is onderneem. ‘n Gerieflikheidsteekproef is gebruik om die deelnemers te verkry. Een hondered en sestig persone is genader en 66.3% (n = 106) het aan die studie deelgeneem. Die datainsamelingsmetode was self-rapportering met behulp van ’n vraelys en beskrywende statistiek is gebruik om die data te verwerk. Orale mukositis was ’n algemene probleem, aangesien 71.7% (n = 76) van die respondente die simptoom ondervind het. Pyn was nie goed beheer nie, aangesien 69.8% (n = 53) pyn ondervind het terwyl slegs 17.1% (n = 13) aangedui het dat hulle analgetika gebruik het. Meer as die helfte van die respondente het voorgeskrewe mond en keel preparate gebruik, terwyl 28.9% (n = 22) self gemedikeer het wat potensi le nadelige preparate ingesluit het. ’n Beduidende verskil is tussen die gebruik van nie voorgeskrewe medikasie en die duur van mukositis bevind (χ2 = 0.81; p = 0.01). Die graad van die mukositi
Blocking Babesia bovis vaccine reactions of dairy cattle in milk
Michael P. Combrink,Graham Carr,Ben J. Mans,Frances Marais
Onderstepoort Journal of Veterinary Research , 2012,
Abstract: The use of 1.16 mg/kg (one third) of the recommended dose of diminazene aceturate, administered indiscriminately to cattle on day seven of the unfrozen Babesia bovis and Babesia bigemina bivalent live blood vaccine reaction, was an infection and block treatment method of immunisation used successfully with no known adverse effect on the parasites or the development of protective immunity. Continuing with this practice after replacement of the unfrozen vaccine with deep-frozen monovalent B. bovis and B. bigemina live blood vaccines resulted in reports of vaccine failure. Laboratory investigation indicated the harmful effect of block treatment in preventing the development of durable immunity against B. bigemina as opposed to the much lesser effect it had on B. bovis. Consequently the practice was no longer recommended. A B. bovis vaccination attempt aimed at controlling the disease of dairy cows in milk (n = 30) resulted in 20% fatalities during the expected vaccine reaction period. The practice of block treating B. bovis was therefore reinvestigated, this time in a field trial using dairy cattle in milk (n = 11). Using 0.88 mg/kg (one quarter) of the recommended dose of diminazene administered on day 12 of the B. bovis vaccine reaction resulted in only two animals (n = 5) testing ≥ 1/80 positive with the indirect fluorescent antibody test (IFAT) although parasites could be demonstrated in three. In the untreated control group, by contrast, five of the vaccinated animals (n = 6) tested ≥ 1/80 positive with IFAT and parasites could be demonstrated in all. The unsatisfactory outcome obtained in this study, combined with that of the earlier investigation, indicated that there are more factors that influence successful vaccination than previously considered. It is therefore concluded that block treatment of the live frozen South African cattle babesiosis vaccines reactions is not recommended.
Survival of Vibrio cholerae in industrially polluted water, with particular reference to iron concentrations
Mrudulalsaacson Margaretha Patel, Hendrik J Koornhof
Water SA , 2004,
Abstract: High levels of iron are often found in surface waters due to the discharge of iron-containing industrial effluents. The effect of iron as well as pH on the survival of Vibrio cholerae (non-O1, El Tor and classical strains) in water samples from 12 points, where selected industrial effluents were discharged into rivers, was studied. All three V. cholerae strains survived longest during spring. V. cholerae non -O1 survived significantly longer than El Tor and classical strains. At pH 8.0, the survival of V. cholerae increased with increase in iron concentration (1 to10 mg/ ) of polluted water. At lower than pH 8.0, the effect of iron was not significant. In polluted water, at pH 8.0, the presence of iron resulted in prolonged V. cholerae survival at lower concentrations than those required for survival in distilled water. We suggest that chemical contamination of water may be one of the important factors instrumental in the subsequent ability of V. cholerae to persist, multiply and survive in the aquatic environment. Water SA Vol.30(1): 65-69
A. Combrink
Koers : Bulletin for Christian Scholarship , 2003, DOI: 10.4102/koers.v68i1.324
Abstract: In a volume of Koers largely dedicated to emeritus Archbishop Desmond Tutu, the following extract from the commendatio deserves special attention: He never failed to emphasise that forgiveness and reconciliation can never be cheap, but can only be achieved through equal justice for all citizens. This was the reason why he fought with his whole being and all the means at his disposal against the unjust, inhuman and unbiblical ideology of apartheid. He did so long before this university distanced itself from apartheid, first through some lonely voices in the seventies and finally in 1996. The Potchefstroom University for Christian Higher Education has the greatest respect, appreciation and admiration for the way in which this fellow-Christian consistently, openly, boldly and unashamedly lived out basic Christian principles like justice, truth, reconciliation and peace.
Serenity—Uses in the Care of Chronically Ill Older Patients: A Concept Clarification  [PDF]
Margaretha Norell Pejner
Open Journal of Nursing (OJN) , 2015, DOI: 10.4236/ojn.2015.51001
Abstract: Serenity is an emotional experience that contributes to the acceptance of a situation. One phenomenon in the care of chronically ill older patients and patients in end of life care is that too much focus is placed on the patient’s disease. This can contribute to anxiety, sadness or sense of isolation. For older people that are chronically ill or in care at the end of life, it is important that the registered nurse can help them to find serenity. Further knowledge is needed about how the concept of serenity is used in relation to the care of older chronically ill patients. Aim: The purpose of this concept analysis was to clarify how serenity is used in nursing and in relation to the care of chronically ill older patients. Method: The study follows Rodgers’ evolutionary method of concept analysis. Findings: Serenity is a state of physical, mental, emotional and spiritual balance when life conditions can be managed or accepted. Through the experience of serenity the chronically ill older patient is able to find or develop the self in order to continue with dignity. The concept is most used at the lowest described levels of the self, including a perception of personal safety. The highest level involves a sense of wholeness and awareness. Conclusion: The concept of serenity is used in relation to chronically ill older patients as a condition where the patient finds balance and thus can manage or accept their situation. Chronically ill older patients will not recover. For that reason it needed a better understanding about what factors to experience serenity are needed. Further research is also needed to examine how registered nurses can support older chronically patients in finding serenity with the help of nursing interventions.
Floristic Composition, Diversity and Structure of the Rainforest in the Mayoko District, Republic of Congo  [PDF]
Margaretha W. van Rooyen, Noel van Rooyen, Edmond S. Miabangana, Gilbert Nsongola, Caroline Vasicek Gaugris, Jér?me Y. Gaugris
Open Journal of Forestry (OJF) , 2019, DOI: 10.4236/ojf.2019.91002
Abstract: Botanically, the Mayoko district is known only through anecdotal descriptions made in the colonial era. The present study was undertaken as part of the prerequisite for a mining feasibility study where a benchmark of the floristic composition, diversity and structure of the vegetation was needed to evaluate potential biodiversity offset areas and to guide species selection for post-mining re-vegetation. The study area comprised approximately 160,000 ha and 235 sample sites were surveyed using the Braun-Blanquet method of phytosociology. Diversity of each plant association was expressed in terms of various diversity parameters. Twelve associations were described and mapped. The associations ranged from highly disturbed and degraded to fairly intact forest associations. A wet to dry gradient and permanently inundated to temporary inundated gradient could also be distinguished. The approach followed here proved remarkably robust in illustrating the complexity in a topographically complex region of the Chaillu Massif. The data provided a high level of insight into the possible dynamics of the rainforest and indications as to possible successional pathways. This information provides a better level of understanding of forest structure and evolution potential than studies limited to trees, remote sensing carbon assessments, or time change series.
Adults with Attention-Deficit/Hyperactivity Disorder – A Brain Magnetic Resonance Spectroscopy Study
Margaretha Dramsdahl,Kerstin J. Plessen,Kenneth Hugdahl,Karsten Specht
Frontiers in Psychiatry , 2011, DOI: 10.3389/fpsyt.2011.00065
Abstract: Background: Impaired cognitive control in individuals with attention-deficit/hyperactivity disorder (ADHD) may be related to a prefrontal cortical glutamatergic deficit. We assessed the glutamate level in the left and the right midfrontal region including the anterior cingulate cortex in adults with ADHD and healthy controls. Methods: Twenty-nine adults with ADHD and 38 healthy controls were included. We used Proton Magnetic Resonance Imaging with single voxel point-resolved spectroscopy to measure the ratio of glutamate to creatine (Glu/Cre) in the left and the right midfrontal region in the two groups. Results: The ADHD group showed a significant reduction of Glu/Cre in the left midfrontal region compared to the controls. Conclusion: The reduction of Glu/Cre in the left midfrontal region in the ADHD group may reflect a glutamatergic deficit in prefrontal neuronal circuitry in adults with ADHD, resulting in problems with cognitive control.
Uit die oogpunt van die buitestander: die rol van identiteit en ruimte in die skep van 'n gemeenskapseie jeugnovelle
A Combrink, F Greyling
Tydskrif vir letterkunde , 2008,
Abstract: The reading habits (or lack thereof) of adolescents in South Africa, like those in the rest of the world, are reason for concern. The fact that adolescents read distressingly little can be attributed to different reasons. It may be because of a lack of skill and interest, or because there is a dearth of texts with which they can identify. If more texts were created in which adolescents can identify with the spaces and identities portrayed, the reading statistics in South Africa may shift positively. However, at present not all communities and voices in the country are represented by a diversity of writers, especially writers of youth literature. In the Afrikaans speaking coloured community of Promosa, Potchefstroom, the same tendency is found. Although it is ideal that these communities should be represented by their own writers, who know them best, this is not always the case. Is it therefore possible for an outsider to create a youth novel for a specific target group with which they (the adolescents of Promosa) will identify?
Sociocultural and political values in selected plays by South African playwrights
A. L. Combrink
Koers : Bulletin for Christian Scholarship , 1985, DOI: 10.4102/koers.v50i3.1051
Abstract: The paper deals with the issue of values expressed in South African plays, and takes a look at representative plays from the entire spectrum of South African drama - Afrikaans, English, Black drama and alternative Theatre. Following a survey of the field, discussions are provided of selected plays in all the sections. It emerges that there is a fair amount of homogeneity right across the board in terms of sociocultural and political values. There is also a strong insistence on value linked to Black consciousness in the plays by Black playwrights, which is important in view of the fact that the Black playwrights often have an overtly didactic and propagandists intention.
Die universiteit: sy aard en die rol van die intellektueel
A.L. Combrink
Koers : Bulletin for Christian Scholarship , 2008, DOI: 10.4102/koers.v73i1.157
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