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Search Results: 1 - 10 of 2730 matches for " Margaret Kendall "
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Public use of the Internet at Chester library, UK.
Katherine Turner,Margaret Kendall
Information Research: an international electronic journal , 2000,
Abstract: Substantial investment is accelerating the provision of public access to the Internet in UK public libraries. Monitoring and evaluation will be essential to inform policies, developments and justify the new services. This paper reports on quantitative and qualitative research into the use being made of the Internet facilities at Chester Library between August 1998 and May 1999. A questionnaire survey of 178 users revealed substantial use by non-library members, mostly aged between 16 and 35, with only slightly higher use by men than by women. Most of the sample had received no formal training in Internet use and the most popular application was e-mail. Follow-up interviews with 9 users provide examples of the value of the service to users and recommendations for increased training and support from librarians. Analysis of the results includes recommendations for Chester libraries and contributes to the wider debate on the changing roles of public libraries. Further research on the monitoring and evaluation of IT-based services in public libraries is now underway at Manchester Metropolitan University, with Cheshire libraries being one of three library authority project partners in VITAL, an 18 month study funded by the Library and Information Commission.
Enhancing the Library and Information Management curriculum through Reusable Learning Objects
Margaret Kendall,Nicola Wakefield,Rachel Delbridge
ITALICS , 2007,
Abstract: Increased communication with practitioners and improved curriculum coverage of specialist sectors have been identified as priorities for Library and Information Management (LIM) educators. This paper discusses a project exploring the potential for reusable learning objects (RLOs) as a response. Ten reusable learning objects on law librarianship, one of which was then repurposed for the health information sector, were created in consultation with practitioners and their use evaluated using an action research strategy. The issues which arose during the creation and deployment of the RLOs are discussed, including granularity, interoperability, levels of learning activity and impact. Positive feedback from both students and practitioners indicates the value of the approach.
Adipose Tissue-Specific Deletion of 12/15-Lipoxygenase Protects Mice from the Consequences of a High-Fat Diet
Banumathi K. Cole,Margaret A. Morris,Wojciech J. Grzesik,Kendall A. Leone
Mediators of Inflammation , 2012, DOI: 10.1155/2012/851798
Adipose Tissue-Specific Deletion of 12/15-Lipoxygenase Protects Mice from the Consequences of a High-Fat Diet
Banumathi K. Cole,Margaret A. Morris,Wojciech J. Grzesik,Kendall A. Leone,Jerry L. Nadler
Mediators of Inflammation , 2012, DOI: 10.1155/2012/851798
Abstract: Type 2 diabetes is associated with obesity, insulin resistance, and inflammation in adipose tissue. 12/15-Lipoxygenase (12/15-LO) generates proinflammatory lipid mediators, which induce inflammation in adipose tissue. Therefore we investigated the role of 12/15-LO activity in mouse white adipose tissue in promoting obesity-induced local and systemic inflammatory consequences. We generated a mouse model for fat-specific deletion of 12/15-LO, aP2-Cre; 12/15-LOloxP/loxP, which we call ad-12/15-LO mice, and placed wild-type controls and ad-12/15-LO mice on a high-fat diet for 16 weeks and examined obesity-induced inflammation and insulin resistance. High-fat diet-fed ad-12/15-LO exhibited improved fasting glucose levels and glucose metabolism, and epididymal adipose tissue from these mice exhibited reduced inflammation and macrophage infiltration compared to wild-type mice. Furthermore, fat-specific deletion of 12/15-LO led to decreased peripheral pancreatic islet inflammation with enlarged pancreatic islets when mice were fed the high-fat diet compared to wild-type mice. These results suggest an interesting crosstalk between 12/15-LO expression in adipose tissue and inflammation in pancreatic islets. Therefore, deletion of 12/15-LO in adipose tissue can offer local and systemic protection from obesity-induced consequences, and blocking 12/15-LO activity in adipose tissue may be a novel therapeutic target in the treatment of type 2 diabetes. 1. Introduction Obesity is a rising worldwide epidemic affecting approximately one-third of adults [1]. Obesity is characterized by a persistent exposure to excess nutrients that leads to visceral adiposity and hyperlipidemia, promoting chronic inflammation, insulin resistance, and endoplasmic reticulum stress [2, 3]. This promotes the development of adipocyte dysfunction and systemic decline, including damage to the pancreas, liver, and vascular tissue. Therefore obesity predisposes individuals to the development of type 2 diabetes and cardiovascular disease. Increasing evidence from our lab suggests that the 12/15-lipoxygenase (12/15-LO) enzyme plays a critical role in promoting adipocyte dysfunction. 12/15-LO oxygenates polyunsaturated fatty acids to generate many proinflammatory lipid mediators (reviewed in [4]). 12/15-LO is largely involved in metabolizing arachidonic acid to form 12-hydroperoxyeicosatetraenoic acid (12-HPETE) and linoleic acid to form 13-hydroperoxyoctadecadienoic acid (13-HPODE), which are further oxidized to 12-hydroxyeicosatetraenoic acid (12(S)-HETE) and 13-hydroxyoctadecadienoic acid
Opening a Window to the Autistic Brain
Kendall Powell
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.0020267
Going against the Grain
Kendall Powell
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.0050338
Economy of the Mind
Kendall Powell
PLOS Biology , 2012, DOI: 10.1371/journal.pbio.0000077
Corpora from a sociolinguistic perspective
Kendall, Tyler;
Revista Brasileira de Linguística Aplicada , 2011, DOI: 10.1590/S1984-63982011000200005
Abstract: in this paper, i consider the use of corpora in sociolinguistic research and, more broadly, the relationships between corpus linguistics and sociolinguistics. i consider the distinction between "conventional" and "unconventional" corpora (beal et al. 2007a, b) and assess why conventional corpora have not had more traction in sociolinguistics. i then discuss the potential utility of corpora for sociolinguistic study in terms of the recent trajectory of sociolinguistic research interests (eckert under review), acknowledging that, while many sociolinguists are increasingly using more advanced corpus-based techniques, many are, at the same time, moving away from corpus-like studies. i suggest two primary areas where corpus developers, both sociolinguistic and non-, could focus to develop more useful corpora: corpora containing a wider range of non-standard (spoken) varieties and more flexible annotation and treatment of spoken language data.
Was ist Kritische Diskursanalyse? What Is Critical Discourse Analysis? Qué es el análisis del discurso crítico?
Gavin Kendall
Forum : Qualitative Social Research , 2007,
Abstract: In diesem Interview schildert Ruth WODAK die Anf nge ihrer Karriere und was sie in das Feld der Kritischen Diskursanalyse geführt hat. Sie legt dar, was an der Kritischen Diskursanalyse "kritisch" ist, differenziert "Kritik" von "Dogmatismus" und thematisiert die Beziehung zwischen Kritik und einer normativen Position. An Ende des Interviews stellt sie in Aussicht, dass eine "integrative Interdisziplinarit t" ein Weg sein kann, um disziplin re Inkommensurabilit t zu überwinden. URN: urn:nbn:de:0114-fqs0702297 In this interview, Ruth WODAK discusses the beginnings of her career, and what propelled her into critical discourse analysis. She analyses what makes critical discourse analysis "critical", distinguishes criticalness from dogmatism, but expounds upon the relationship between critique and norms. Finally, she discusses how "integrative indisciplinarity" might help us with problems of disciplinary incommensurability. URN: urn:nbn:de:0114-fqs0702297 En esta entrevista, Ruth WODAK comenta los orígenes de sus preocupaciones y lo que la empujó al análisis del discurso crítico. La autora analiza qué hace "crítico" al análisis del discurso crítico, qué distingue a la crítica del dogmatismo y qué relación existe entre la primera y las normas. Por ultimo, discute cómo "la indisciplinariedad integradora" puede ayudarnos con los problemas que presenta la inconmensurabilidad disciplinaria. URN: urn:nbn:de:0114-fqs0702297
Descriptions of Four New Forms ofEriophyes
James Kendall
Psyche , 1929, DOI: 10.1155/1929/85898
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