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Search Results: 1 - 10 of 12779 matches for " Marcelo Llancaqueo "
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Aterosclerosis en sujetos con periodontitis
López,Néstor J; Chamorro,Adriana; Llancaqueo,Marcelo;
Revista médica de Chile , 2011, DOI: 10.4067/S0034-98872011000600004
Abstract: background: chronic infl ammation and infections are involved in the development and progression of atherosclerotic vascular disease. aim: to evaluate the association between periodontitis and early atherosclerosis. material and methods: fifty-three subjects who received periodontal treatment and regular maintenance for at least 10 years, and 55 subjects with periodontitis but without a history of periodontal treatment were studied. carotid artery intima-media wall thickness (cimt) was measured with high-resolution b-mode ultrasonography. a blood sample was obtained to measure high sensitivity c-reactive protein, fibrinogen, lipoprotein cholesterol, leukocyte count and erythrocyte sedimentation rate. covariates included age, gender, smoking, level of education, body mass index and physical activity. the benzoyl-dl-arginine-naphthylamide (bana) test was used to determine the number of periodontal sites with periodontal pathogens. results: cimt value was significantly higher in subjects with periodontitis than those without it (0.775 ± 0.268 and 0.683 ± 0.131 mm respectively, p = 0.027). c-reactive protein, leukocyte count and percentage of sites with periodontal pathogens were also significantly higher in subjects with periodontitis. regression analysis identified age, periodontitis, and smoking as independent predictors of cimt. conclusions: these results suggest that untreated periodontitis is associated with early atherosclerotic carotid lesions and higher levels of infl ammatory markers.
Aterosclerosis en sujetos con periodontitis Association between atherosclerosis and periodontitis
Néstor J López,Adriana Chamorro,Marcelo Llancaqueo
Revista médica de Chile , 2011,
Abstract: Background: Chronic infl ammation and infections are involved in the development and progression of atherosclerotic vascular disease. Aim: To evaluate the association between periodontitis and early atherosclerosis. Material and Methods: Fifty-three subjects who received periodontal treatment and regular maintenance for at least 10 years, and 55 subjects with periodontitis but without a history of periodontal treatment were studied. Carotid artery intima-media wall thickness (CIMT) was measured with high-resolution B-mode ultrasonography. A blood sample was obtained to measure high sensitivity C-reactive protein, fibrinogen, lipoprotein cholesterol, leukocyte count and erythrocyte sedimentation rate. Covariates included age, gender, smoking, level of education, body mass index and physical activity. The benzoyl-DL-arginine-naphthylamide (BANA) test was used to determine the number of periodontal sites with periodontal pathogens. Results: CIMT value was significantly higher in subjects with periodontitis than those without it (0.775 ± 0.268 and 0.683 ± 0.131 mm respectively, p = 0.027). C-reactive protein, leukocyte count and percentage of sites with periodontal pathogens were also significantly higher in subjects with periodontitis. Regression analysis identified age, periodontitis, and smoking as independent predictors of CIMT. Conclusions: These results suggest that untreated periodontitis is associated with early atherosclerotic carotid lesions and higher levels of infl ammatory markers.
Efectos del tratamiento periodontal sobre los marcadores de inflamación sistémica en pacientes con riesgo de enfermedad cardiaca coronaria: Estudio piloto
López,Néstor J; Quintero,Antonio; Llancaqueo,Marcelo; Jara,Lilian;
Revista médica de Chile , 2009, DOI: 10.4067/S0034-98872009001000006
Abstract: background- studies investigating effects of periodontal treatment (pt) on markers of inflammation in healthy subjects show conflicting results. few studies have investigated the effects ofpt among subjects with coronary heart disease (chd) risk factors. aim: to report the results of a pilot prospective study on the effects of periodontal treatment on markers of inflammation among subjects with chd risk factors. material and methods: seventy three patients aged 53±6 years (25% males) with chronic periodontitis, dyslipidemia and other chd risk factors were subjected to pt consisting on root planning and oral metronidazol and amoxicillin for 7 days. periodontal clinical parameters, serum c-reactive protein (crp), fibrinogen levels and erythrocyte sedimentation rate (esr) were assessed before and at 6 weeks a?erpt. polymorphisms at the illa-889 andil1b+3954genes were also genotyped. results: after the treatment period, crp levels significantly increased from 3.6±3.7 mg/ l to 5.4±5.7 mg/l (p =0.001). no significant changes were observed in fibrinogen levels and esr. higher post-treatment crp levels were significantly associated with the composite polymorphic genotype at the illa-889 and il1b+3954 genes (p =0.0001), and extensive periodontitis (p =0.005). moderate alcohol consumption appeared as a protective factor for crp elevation (p =0.029). conclusions: the increase of the crp levels after pt in patients with cvd risk factors appeared associated with il-1 gene polymorphisms and extensive periodontitis.
Disección aórtica tipo B y embarazo en un síndrome de Marfán: manejo y resultado
Jorge Hasbun H,Marcelo Llancaqueo V,Cristóbal Ramos G,Carolina Urrejola N
Revista Chilena de Obstetricia y Ginecología , 2012,
Abstract: El síndrome de Marfán es una enfermedad autosómica dominante del tejido conectivo, multisistémica y pronóstico determinado por las complicaciones cardiovasculares. Se presenta una paciente de 32 a os, multípara, con el diagnóstico conocido de cinco a os, posterior a disección aórtica toraco-abdominal (Standford B) y embarazo actual no planificado. Es manejada con betabloqueadores y las imágenes seriadas de aorta muestran disección estable en el segmento entre subclavia izquierda e ilíaca derecha con 41,8 mm en su diámetro mayor, sin comprometer la irrigación de órganos abdominales. Ingresa a las semana 32 para evaluación multidisciplinaria y parto programado. El examen con resonancia nuclear magnética de columna lumbosacra evidenció ectasia dural marcada a nivel de raíz S2. La evaluación fetal demostró un crecimiento en percentil 20 con bienestar hemodinámico y ecocardiografía normal. Previa inducción de madurez pulmonar y con 34+3 semanas, se efectúa cesárea electiva bajo anestesia espinal continua, con nacimiento sin compresión del fondo uterino, esterilización tubaria y postoperatorio inmediato en Unidad Coronaria por 48 horas. La evolución materna es sin incidentes. El recién nacido presentó enterocolitis necrotizante con buena respuesta al tratamiento médico. Marfan syndrome is a multysistemic an autosomal-dominant disorder of connective tissue and cardiovascular complications determine its prognosis. We present a 32 year-old patient diagnosed five years previously after thoraco-abdominal aneurysm Standford B, and a current unplanned pregnancy. She was treated with beta blockers and evaluated with serial images of the aorta showing a stable thoraco-abdominal aneurysm initiated at the left subclavian artery to the right iliac artery of 41.8 mm at maximum diameter. The patient was hospitalized at 32 weeks to be evaluated in a multidisciplinary team planned delivery. Nuclear Magnetic Resonance on maternal spine detected dural ectasia at S2 and fetal evaluation shows growing at 20 percentile, hemodinamical wellbeing and normal echocardiography. After corticosteroids at 34 +3 weeks a cesarean section with tubal sterilization is performed, with continuous spinal anesthesia, without uterus compression and inmediate postoperative care at the Coronary Unit for 48 hours with satisfactory maternal evolution. The newborn presented a necrotizing enterocolitis at 7 days improving with medical therapy.
Efectos del tratamiento periodontal sobre los marcadores de inflamación sistémica en pacientes con riesgo de enfermedad cardiaca coronaria: Estudio piloto Effects of periodontal therapy on markers of systemic inflammation in patients with coronary heart disease risk
Néstor J López,Antonio Quintero,Marcelo Llancaqueo,Lilian Jara
Revista médica de Chile , 2009,
Abstract: Background- Studies investigating effects of periodontal treatment (PT) on markers of inflammation in healthy subjects show conflicting results. Few studies have investigated the effects ofPT among subjects with coronary heart disease (CHD) risk factors. Aim: To report the results of a pilot prospective study on the effects of periodontal treatment on markers of inflammation among subjects with CHD risk factors. Material and methods: Seventy three patients aged 53±6 years (25% males) with chronic periodontitis, dyslipidemia and other CHD risk factors were subjected to PT consisting on root planning and oral metronidazol and amoxicillin for 7 days. Periodontal clinical parameters, serum C-reactive protein (CRP), fibrinogen levels and erythrocyte sedimentation rate (ESR) were assessed before and at 6 weeks a erPT. Polymorphisms at the ILlA-889 andIL1B+3954genes were also genotyped. Results: After the treatment period, CRP levels significantly increased from 3.6±3.7 mg/ L to 5.4±5.7 mg/L (p =0.001). No significant changes were observed in fibrinogen levels and ESR. Higher post-treatment CRP levels were significantly associated with the composite polymorphic genotype at the ILlA-889 and IL1B+3954 genes (p =0.0001), and extensive periodontitis (p =0.005). Moderate alcohol consumption appeared as a protective factor for CRP elevation (p =0.029). Conclusions: The increase of the CRP levels after PT in patients with CVD risk factors appeared associated with IL-1 gene polymorphisms and extensive periodontitis.
Medición de la carga embólica y relación ventrículo derecho/ventrículo izquierdo en tomografía computada como indicadores de riesgo en pacientes con tromboembolismo pulmonar
Díaz,Juan Carlos; Ladrón de Guevara,David; Pereira,Gonzalo; Herrmann,Rodrigo; Silva,Claudio; Astorga,Erika; Llancaqueo,Marcelo;
Revista médica de Chile , 2007, DOI: 10.4067/S0034-98872007001100010
Abstract: background: in pulmonary embolism, the computed tomography (ct) images can be used as a prognostic index measuring the embolic load, according to the location and size of thrombus and the right/left ventricular diameter ratio. aim to assess the predictive value of embolic load and right/left ventricular diameter ratio for early and ?ate mortality in acute pulmonary embolism (pte). material and methods: the pulmonary ct of 418 patients with suspected pte were reviewed. embolic load was assessed by three independent evaluators and the right/left ventricular diameter ratio was measured in those exams that were positive for pte. a logistic regression analysis was done between these parameters and mortality. reproducibuity was calculated using bland andaltman analysis. results: there was a high concordance between raters to calculate embolic load (r =0,95, p <0,001). only the right/left ventricular diameter ratio and the presence were predictive of global mortality. the predictive value for embolic load was below the significance level no parameter was predictive of early mortality. conclusions: the concordance between raters for the assessment of embolic load was high in this study. however no imaging parameter had a predictive value for early mortality. the right/left ventricular diameter ratio had a predictive value for global mortality at three months
Cetólidos, una nueva generación de antimicrobianos KETOLIDES, A NEW GENERATION OF ANTIMICROBIAL AGENTS
ALVARO LLANCAQUEO V
Revista chilena de infectología , 2002,
Abstract:
Disección aórtica tipo B y embarazo en un síndrome de Marfán: manejo y resultado
Hasbun H,Jorge; Llancaqueo V,Marcelo; Ramos G,Cristóbal; Urrejola N,Carolina; Cerda SM,Sergio; Norambuena N,Constanza; Zamorano G,Jaime;
Revista chilena de obstetricia y ginecología , 2012, DOI: 10.4067/S0717-75262012000200010
Abstract: marfan syndrome is a multysistemic an autosomal-dominant disorder of connective tissue and cardiovascular complications determine its prognosis. we present a 32 year-old patient diagnosed five years previously after thoraco-abdominal aneurysm standford b, and a current unplanned pregnancy. she was treated with beta blockers and evaluated with serial images of the aorta showing a stable thoraco-abdominal aneurysm initiated at the left subclavian artery to the right iliac artery of 41.8 mm at maximum diameter. the patient was hospitalized at 32 weeks to be evaluated in a multidisciplinary team planned delivery. nuclear magnetic resonance on maternal spine detected dural ectasia at s2 and fetal evaluation shows growing at 20 percentile, hemodinamical wellbeing and normal echocardiography. after corticosteroids at 34 +3 weeks a cesarean section with tubal sterilization is performed, with continuous spinal anesthesia, without uterus compression and inmediate postoperative care at the coronary unit for 48 hours with satisfactory maternal evolution. the newborn presented a necrotizing enterocolitis at 7 days improving with medical therapy.
El aprendizaje del concepto de campo en física: una investigación exploratoria a luz de la teoría de Vergnaud
Llancaqueo, Alfonso;Caballero, Ma Concesa;Moreira, Marco Antonio;
Revista Brasileira de Ensino de Física , 2003, DOI: 10.1590/S1806-11172003000400011
Abstract: results of a study on the acquisition of the field concept in physics by high school and college freshmen students, carried out under the framework of vergnaud's conceptual fields theory, are presented. the aims of the study were to explore the links between students' cognitive structure and the formal structure of the field concept in physics, and to describe their levels of conceptualization of such a concept. research findings confirm the potentialities of vergnaud's theory to understand and explain the learning process of this basic physical concept. the links would manifest themselves in the use of symbolic representations and in a partial explicitation of some meanings that would suggest the presence of some operational invariants students use to cope with situations and problems that require an acceptable scientific conceptualization. however, a clear absence of scientifically accepted operational invariants was observed. about 92% of the students were located at the lowest level of a 1 to 3 conceptualization scale defined in the study, where 3 corresponds to the recognition and partial acquisition of meanings of the field concept. this low level of conceptualization correlates with poor performance in the following categories of analysis : operational (17, 6 %), written expression (17,3%), symbolic representation (13,6%), and problem solving (5,5%). these results agree with vergnaud's theory that states that a low level of conceptualization corresponds to lower levels of explicitation of operational invariants and their representations, and predomination of procedural aspects over conceptually richer predicates.
El aprendizaje del concepto de campo en física: una investigación exploratoria a luz de la teoría de Vergnaud
Llancaqueo Alfonso,Caballero Ma Concesa,Moreira Marco Antonio
Revista Brasileira de Ensino de Física , 2003,
Abstract: Se presentan resultados de una investigación del concepto de campo, con alumnos de Bachillerato y primer a o de Universidad, en el marco de la teoría de campos conceptuales de Vergnaud, adoptada como referencial teórico para comprender y explicar el proceso de aprendizaje de este concepto fundamental de la física. El propósito fue explorar vínculos entre la estructura cognitiva de los estudiantes y la estructura del concepto de campo construido por la física, y describir niveles de conceptualización del concepto. Los resultados confirman potencialidades de la teoría para abordar estos vínculos, que se manifiestan en el uso de representaciones simbólicas y una explicitación parcial de significados, que dan forma a invariantes operatorios que usan para enfrentar situaciones y problemas que demandan una conceptualización científica aceptable. Se observa una ausencia notoria de invariantes para enfrentar situaciones y problemas propuestos. El 92,7 % de los estudiantes se ubica en los niveles más bajos de conceptualización del concepto de campo (niveles 1, 2 y 3 definidos en este estudio), donde el nivel 3 corresponde a un reconocimiento y explicación parcial de significados del concepto. Este bajo nivel es concordante con bajos desempe os en las categorías de análisis, de operación (17,6 %), expresión escrita (17,3 %), representación (13,6 %) y resolución (5,5 %), en acuerdo con la teoría de Vergnaud, que afirma que un bajo nivel de conceptualización se caracteriza por bajos niveles de explicitación de invariantes y sus representaciones, con predominio de aspectos procedimentales de las operaciones sobre el uso de predicados de mayor riqueza conceptual.
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