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Search Results: 1 - 10 of 613870 matches for " María Laura de la Barrera "
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Diagnóstico diferencial de envejecimiento patológico. Desempe os en el Addenbrooke's Cognitive Examination (ACE)
María Laura de la Barrera,Danilo Donolo
Pensamiento Psicológico , 2009,
Abstract: La presente investigación tiene como objetivo conocer los porcentajes de adultos que manifiestan cierta predisposición a padecer demencia fronto-temporal (DFT) o demencia tipo Alzheimer (DTA), por el valor obtenido en el coeficiente VLOM (siglas en inglés de los subtests de fluidez verbal + lenguaje / orientación + recuerdo diferido) y si estos valores pueden variar en función de género, edad a os de escolaridad y antecedentes de enfermedad. Se trabajó con 649 sujetos adultos de la ciudad de Río Cuarto, Córdoba, Argentina con la aplicación del instrumento ACE (Addenbrooke's Cognitive Examination) de Mathuranath, Néstor, Berríos, Rakowicz y Hodges (2000), en una versión adaptada. Se llevaron a cabo análisis Chi cuadrado para conocer si existen diferencias en los desempe os en el instrumento por grupos. Los resultados manifiestan que no aparecen diferencias significativas por género, pero sí se evidencian ciertas tendencias por edad, a os de escolaridad y antecedentes de enfermedad.
Evaluación a largo plazo del estado nutricional, composición corporal y densidad mineral ósea en mujeres operadas de bypass gástrico: impacto del nivel socioeconómico Nutritional status, body composition and bone mineral density in gastric bypass females: impact of socioeconomic level
Maríaa de la Maza,Laura Leiva,Gladys Barrera,Carolina Boggiano
Revista médica de Chile , 2008,
Abstract: Background: Roux-en-Y gastric bypass (RYGBP) has had a positive impact on co-morbidities associated with obesity. However, in the long-term it can induce micronutrient deficiencies. Aim: To perform a complete nutritional assessment in a group of women previously operated of RYGBP, from different socioeconomic levéis (SEL). Patients and Methods: Thirty three women (19 high SEL and 14 low SEL), were assessed by dietary recalls, anthropometric measurements, muscle strength, bone mineral density, routine clinical laboratory, serum levéis of vitamin B12, 250H-vitamin D, Mate, calcium, ferritine, ceruloplasmin and indicators ofbone turnover (parathohormone, osteocalcin and urinary pyridinolines). Their valúes were compared to those of 30 control women (18 high SEL and 12 low SEL). Results: Low SEL operated women consumed fewer vitamin and mineral supplements compared with their high SEL pairs. No cases of vitamin B12, folie acid or copper deficiencies were detected. Frequency of iron deficieney was similar in patients and controls. Vitamin D insufficieney was higher amongpatients than in controls (p =0,04 7), regardless SEL. Patients had also a higher frequency of high serum PTH and osteocalcin and urinary pyridinoline levéis. However, no differences in bone mineral density were observed between operated women and controls. Conclusions: Vitamin and mineral deficiencies were lower than expected among operated women. However, problems associated with vitamin D deficieney were highly prevalent among patients operated of RYGBP, irrespective SEL. These alterations were only detectable through speci e markers at this stage, because they did not transíate into lower bone mineral density (BMD) of surgicalpatients, probably due to the higher pre-operative BMD of these morbidobese patients.
INTELIGENCIA EMOCIONAL Y AMBIENTES ESCOLARES: UNA PROPUESTA PSICOPEDAGóGICA
María Laura de la Barrera,Danilo Silvio Donolo,Lorena Soledad Acosta,María Mercedes González
Ense?anza e Investigación en Psicología , 2012,
Abstract: El presente escrito destaca el interés por estudiar las características emocionales de ni os que se hallan en contextos escolares desfavorecidos y con carencias marcadas, tales como falta de afecto y contención, escasa capacidad para interactuar positivamente con otros y para manejar los impulsos emocionales, poca motivación y marcada problemática familiar y social. Participaron 18 alumnos de quinto grado de una escuela urbano-marginal de una ciudad argentina y los instrumentos utilizados fueron situaciones dilemáticas, observaciones y entrevistas. Los diversos hallazgos condujeron a elaborar una propuesta de alfabetización emocional desde una perspectiva psicopedagógica.
Efecto del probiótico Saccharomyces boulardii en la prevención de la diarrea asociada con antibióticos en adultos ambulatorios en tratamiento con amoxicilina
Bravo,María Verónica; Bunout,Daniel; Leiva,Laura; de la Maza,Maríaa; Barrera,Gladys; de la Maza,Javier; Hirsch,Sandra;
Revista médica de Chile , 2008, DOI: 10.4067/S0034-98872008000800004
Abstract: background: antibiotic-associated diarrhea is one of the most common adverse effects of antimicrobials. any antimicrobial can potentially produce diarrhea but beta-lactamics have a higher risk. among these, amoxicillin is widely indicated in ambulatory practice. one ofthe alternatives suggested to prevent antibiotic-associated diarrhea, is the use of the probiotic saccharomyces boulardii. aim: to evalúate whether the concomitant use of saccharomyces boulardii and amoxicillin can prevent antibiotic associated diarrhea in ambulatory adults with acute infections diseases, without provoking other adverse effects. material and methods: eighty six adults (aged 15 to 81 years) with acute infectious diseases, excluding those arising in the gastrointestinal tract, that received a prescription of oral amoxicillin for 5 to 10 days, were included. in a controlled randomized, double blind trial, 41 patients were assigned to receive lyophilized saccharomyces boulardii (500 mg/day) duríng 12 days, and 45 patients were assigned to placebo for the same period. results: ten percent of patients (9/86) reported acute diarrhea, 9,8% (4/41) in the experimental group and 11.196 (5/45) in the control group (p = 100). no adverse effects were associated to the use of the probiotic. conclusions: saccharomyces boulardii (500 mg/day) did not prevent diarrhea related to amoxicillin.
Evaluación a largo plazo del estado nutricional, composición corporal y densidad mineral ósea en mujeres operadas de bypass gástrico: impacto del nivel socioeconómico
de la Maza,Maríaa; Leiva,Laura; Barrera,Gladys; Boggiano,Carolina; Herrera,Tomás; Pérez,Yanet; Gattás,Vivien; Bunout,Daniel; Hirsch,Sandra;
Revista médica de Chile , 2008, DOI: 10.4067/S0034-98872008001100007
Abstract: background: roux-en-y gastric bypass (rygbp) has had a positive impact on co-morbidities associated with obesity. however, in the long-term it can induce micronutrient deficiencies. aim: to perform a complete nutritional assessment in a group of women previously operated of rygbp, from different socioeconomic levéis (sel). patients and methods: thirty three women (19 high sel and 14 low sel), were assessed by dietary recalls, anthropometric measurements, muscle strength, bone mineral density, routine clinical laboratory, serum levéis of vitamin b12, 250h-vitamin d, mate, calcium, ferritine, ceruloplasmin and indicators ofbone turnover (parathohormone, osteocalcin and urinary pyridinolines). their valúes were compared to those of 30 control women (18 high sel and 12 low sel). results: low sel operated women consumed fewer vitamin and mineral supplements compared with their high sel pairs. no cases of vitamin b12, folie acid or copper deficiencies were detected. frequency of iron deficieney was similar in patients and controls. vitamin d insufficieney was higher amongpatients than in controls (p =0,04 7), regardless sel. patients had also a higher frequency of high serum pth and osteocalcin and urinary pyridinoline levéis. however, no differences in bone mineral density were observed between operated women and controls. conclusions: vitamin and mineral deficiencies were lower than expected among operated women. however, problems associated with vitamin d deficieney were highly prevalent among patients operated of rygbp, irrespective sel. these alterations were only detectable through speci?e markers at this stage, because they did not transíate into lower bone mineral density (bmd) of surgicalpatients, probably due to the higher pre-operative bmd of these morbidobese patients.
Calidad de vida en pacientes operadas de bypass gástrico hace más de un a?o: Influencia del nivel socioeconómico
Leiva,María José; Fuentealba,Claudio; Boggiano,Carolina; Gattás,Vivien; Barrera,Gladys; Leiva,Laura; Bunout,Daniel; Hirsch,Sandra; de la Maza,M. Pía;
Revista médica de Chile , 2009, DOI: 10.4067/S0034-98872009000500005
Abstract: background: the study of the effects of bariatric surgery on quality of life in patients of different socioeconomic levels (sel) is worthwhile. aim: to study quality of life (qol), eating behavior, depressive symptoms and sexuality in patients subjected to a gastric bypass (gbp) more than 1 year before. material and methods: the sample was composed of 33 gpb patients (19 high sel and 14 low sel), and 27 non-operated women (18 high sel and 9 low sel) of similar weight and age, as controls. assessment included medical history anthropometry radiological densitometry. eating behavior was assessed using the three factor eating questionnaire, quality of life using sf-36 and the bariatric analysis of reporting outcome system (baros) depressive symptoms were assessed using the beck scale version ii and sexual behavior using the female sexual function index (fsfi). results: qol was lower in operated patients from low sel, especially when compared to high sel control women. operated patients had a predominantly restrictive pattern of eating behavior eating behavior disorders were detected in 5 of 33 operated patients versus 4 of 27 controls (p =ns). sexual function was absent or dysfunctional in 22 operated versus 8 controls (p =0,02). no significant differences were observed for depressive symptoms, between operated patients and controls. conclusions: in the long term, qol of bariatric patients, especially those from low sel, is inferior to control women and chilean general population. operated patients have restrictive eating patterns and lower sexual satisfaction indexes. frequency of depressive symptoms was high both in bariatric and control women.
Mycobacterium tuberculosis Multidrug Resistant Strain M Induces an Altered Activation of Cytotoxic CD8+ T Cells
Laura Geffner, Juan Ignacio Basile, Noemí Yokobori, Denise Kviatcovsky, Carmen Sabio y García, Viviana Ritacco, Beatriz López, María del Carmen Sasiain, Silvia de la Barrera
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0097837
Abstract: In human tuberculosis (TB), CD8+ T cells contribute to host defense by the release of Th1 cytokines and the direct killing of Mycobacterium tuberculosis (Mtb)-infected macrophages via granule exocytosis pathway or the engagement of receptors on target cells. Previously we demonstrated that strain M, the most prevalent multidrug-resistant (MDR) Mtb strain in Argentine, is a weak inducer of IFN-γ and elicits a remarkably low CD8-dependent cytotoxic T cell activity (CTL). In contrast, the closely related strain 410, which caused a unique case of MDR-TB, elicits a CTL response similar to H37Rv. In this work we extend our previous study investigating some parameters that can account for this discrepancy. We evaluated the expressions of the lytic molecules perforin, granzyme B and granulysin and the chemokine CCL5 in CD8+ T cells as well as activation markers CD69 and CD25 and IL-2 expression in CD4+ and CD8+ T cells stimulated with strains H37Rv, M and 410. Our results demonstrate that M-stimulated CD8+ T cells from purified protein derivative positive healthy donors show low intracellular expression of perforin, granzyme B, granulysin and CCL5 together with an impaired ability to form conjugates with autologous M-pulsed macrophages. Besides, M induces low CD69 and IL-2 expression in CD4+ and CD8+ T cells, being CD69 and IL-2 expression closely associated. Furthermore, IL-2 addition enhanced perforin and granulysin expression as well as the degranulation marker CD107 in M-stimulated CD8+ T cells, making no differences with cells stimulated with strains H37Rv or 410. Thus, our results highlight the role of IL-2 in M-induced CTL activity that drives the proper activation of CD8+ T cells as well as CD4+ T cells collaboration.
íNDICE GLICéMICO E INSULINEMICO DE DOS TIPOS DE PASTA DE PRESENTACIóN LARGA Y CORTA EN INDIVIDUOS SANOS GLYCEMIC AND INSULINEMIC INDEX OF TWO TYPES OF PASTA OF SHORT AND LONG PRESENTATION IN HEALTHY SUBJECTS
Sandra Hirsch B,Gladys Barrera A,Laura Leiva B,M. Pía de la Maza C
Revista Chilena de Nutricíon , 2010,
Abstract: Introducción: Las pastas secas (industrializadas) se caracterizan por ser manufacturadas a base de harina dura de trigo y otros cereales, llamado semolina, a diferencia del pan que se prepara con harina fina, lo que supone que la respuesta insulinémica y glicémica debiera ser menor que la del pan. Objetivo: Medir la respuesta glicémica e insulinsulinémica de una pasta seca estándar y una pasta seca enriquecida con huevo, de presentación larga (espagueti) y corta (corbata). Material y Métodos: El índice glicémico (IG) e índice insulinémico (II) se determinaron en 10 sujetos sanos entre 26 y 58 a os de edad. En forma aleatoria a cada sujeto se le midió la glicemia e insulina en ayuno y después de ingerir en forma isoglucídica alimento estándar (pan marraqueta) o los 2 tipos de pasta en presentación larga o corta a los 15,45,60,90,120,150 y 180 minutos. Posteriormente se calculó el área bajo la curva (ABC) de glucosa e insulina en cada sujeto. Los IG e II fueron calculados como la razón entre el ABC para un alimento de prueba dado y el ABC del alimento estándar (considerado el 100%). RESULTADOS : Ambos tipos de pasta en presentación larga y corta presentaron menor IG que el alimento estándar (marraqueta) ( pasta larga A: 47,8±54,4, pasta larga B: 58,6±95,4%; pasta corta A:71,4±32,8%, pasta corta B: 79,9±4,.6% p<001). El II de los dos tipos de pasta larga fue menor que el alimento estándar y los mismos tipos de pasta, pero cortas (p<.005). El II de las pastas cortas no se diferenció del alimento estándar. Conclusión: Este estudio demostró que las pastas secas con o sin adición de huevo tienen una menor respuesta glicémica que el alimento estándar, por lo tanto, se pueden clasificar como alimento de bajo IG. Además las pastas de presentación larga tienen una menor respuesta insulinémica. AIM: To measure the glucose and insulin responses of a standard dry pasta and a dry pasta enriched with egg in their long and short presentation. MATERIAL AND METHODS: The glycemic index (GI) and the insulin index (II) were determined in a randomized, cross over protocol in 10 healthy volunteers between 26 and 58 years of age. Each subject underwent ten tests: six with the standard meal (bread) and four with the study pastas. Every study pasta was evaluated 10 times. Blood glucose and insulin levels were measured in the fasted state and over the 180 min following commencement of consumption of the foods. The Area Under the Curve (AUC) was calculated for the values above baseline for the 3-hour period following the meal. GI and II were calculated as the ratio of glucose and i
Determinación de los índices glicémicos y de insulina en fórmulas para alimentación enteral en adultos sanos Glycemic and insulin indices of tube feeding formulas in healthy adults
Vivien Gattás,Gladys Barrera,Laura Leiva,M Pía de la Maza
Revista médica de Chile , 2007,
Abstract: Background: In acute illnesses, plasma glucose levels are often increased and generally parallel the severity of stress. Hyperglycemia caused by reduced insulin sensitivity and reduced insulin secretion is associated with increased susceptibility to infections. Maintaining blood glucose levels at or below 110 mg/dl reduces morbidity and mortality in critically ill patients. Aim: To measure the glucose and insulin responses of four commercially available enteral formulas compared with a standard meal reference product. Material and Methods: The glycemic index (GI) and the insulin index (II) were determined in a randomized, cross over protocol in 38 healthy volunteers between 18 and 46 years of age. Each subject underwent five tests: three with the standard meal (bread) and two with the study products. The enteral formulas were Clinutren HPR (whole protein of high protein value), Crucial (casein peptide based formula), Peptamen , (whey peptide based formula), Glytrol (formula for diabetics with whole protein with fiber). Each study product was evaluated 10 times. Results: The diabetic formula and the high protein energy dense formulas induced a significantly lower GI (p <0.02) compared with the standard meal. The GI response did not appear to be due to enhanced insulin secretion. The other tested formulas had lower GI than the standard meal, but in addition they exhibited increased II The whey based peptide formulation produced the highest insulin response (p <0.03). Conclusions: Both GI and II are related to the concentration, form and type of protein contained in the enteral formula. The whey peptide formulation produced a low GI with the highest insulin index. Based on the low GI of these enteral products, all can be useful to provide nutritional support during metabolic stress, without adding an additional challenge to blood glucose management
íNDICE GLICéMICO E INSULINEMICO DE DOS TIPOS DE PASTA DE PRESENTACIóN LARGA Y CORTA EN INDIVIDUOS SANOS
Hirsch B,Sandra; Barrera A,Gladys; Leiva B,Laura; de la Maza C,M. Pía; Bunout B,Daniel;
Revista chilena de nutrición , 2010, DOI: 10.4067/S0717-75182010000400008
Abstract: aim: to measure the glucose and insulin responses of a standard dry pasta and a dry pasta enriched with egg in their long and short presentation. material and methods: the glycemic index (gi) and the insulin index (ii) were determined in a randomized, cross over protocol in 10 healthy volunteers between 26 and 58 years of age. each subject underwent ten tests: six with the standard meal (bread) and four with the study pastas. every study pasta was evaluated 10 times. blood glucose and insulin levels were measured in the fasted state and over the 180 min following commencement of consumption of the foods. the area under the curve (auc) was calculated for the values above baseline for the 3-hour period following the meal. gi and ii were calculated as the ratio of glucose and insulin auks for a given test meal and the aucs for the standard meal. results: both type of pasta in their long and short presentation had lower gi than the standard meal (long pasta a: 47.8±54.4%, pasta b: 58.6±95.4%; short pasta a:71.4±32.8, pasta b: 79.9±47.6% % p<.001). the ii was lower with the two type of large pasta compare to the standard meal and to the two type of short pasta (p<.005). conclusions: this study has shown that dry pasta with or without addition of egg put in the mass, is low gl food. long dry pasta has lower insulin response.
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