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Search Results: 1 - 10 of 674692 matches for " María Félix Moreno-López "
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Biocontrol de la pudrición de raíz de nochebuena de interior con Trichoderma spp. Root rot biocontrol for indoor poinsettia with Trichoderma spp.
Felipe de Jesús Osuna-Canizalez,María Félix Moreno-López,Faustino García-Pérez,Sergio Ramírez-Rojas
Revista mexicana de ciencias agrícolas , 2012,
Abstract: En Morelos, la pudrición de la raíz causada por Fusarium spp., es una de las principales enfermedades de la nochebuena de interior. Por su efecto devastador, en su prevención o control se realizan aplicaciones frecuentes de productos químicos, con los riesgos inherentes a la salud humana y al ambiente. En la búsqueda de alternativas bioracionales al manejo de esta enfermedad, se realizó un ensayo en el que se evaluaron tres cepas comerciales de Trichoderma spp., en tres diferentes sustratos: S1= "tierra de hoja" (70% v/v)+tezontle grueso (15% v/v)+tezontle fino (10% v/v)+agrolita (5% v/v); S2= turba (80% v/v)+ fibra de coco (20% v/v); S3= "tierra de hoja" (70%) + "tepojal" (30%), en las variedades comerciales más comunes, Freedom Red y Prestige Red. Se utilizó un dise o factorial de tratamientos 4 x 3 x 2 y los tratamientos resultantes se evaluaron en un dise o completamente al azar con seis repeticiones. Respecto a la incidencia de pudrición de la raíz, las cepas comerciales de Trichoderma spp., no mostraron diferencias entre sí ni con el testigo químico. La pudrición de la raíz estuvo asociada con S2, debido a una baja capacidad de aireación, y sólo se presentó en Prestige Red. La población (UFC g-1) de Trichoderma spp., en el sustrato al término del ciclo, fue igual (p< 0.05) entre cepas comerciales y entre estas y el testigo químico (sin inoculación), debido a la presencia de cepas nativas de Trichoderma en los componentes orgánicos de los sustratos ("tierra de hoja", turba y fibra de coco). In Morelos, root rot caused by Fusarium spp., is one of the main diseases of indoor poinsettia. In order to prevent or control its devastating effect, frequent applications of chemical products are performed, with inherent risks to human health and environment. In quest for alternative biorational options, an essay in which three commercial strains of Trichoderma spp., was done, in three different substrates: S1= "organic soil" (70% v/v)+thick tezontle (15% v/v)+thin tezontle (10% v/v)+agrolita (5% v/v); S2= peat moss (80% v/v)+ coconut fiber (20% v/v); S3= "organic soil" (70%)+"tepojal" (30%), in most common commercial varieties, Freedom Red and Prestige Red. A factorial design of 4 x 3 x 2 treatment was used and resulting treatments were evaluated in a completely random design with six repetitions. Regards root rot incidence, commercial strains of Trichoderma spp., did not show differences between them, either with chemical control. Root rot was associated with S2, due low aeration capacity, and only it was seen in Prestige Red. Population of Trichoderma spp.,
Biocontrol de la pudrición de raíz de nochebuena de interior con Trichoderma spp.
Osuna-Canizalez, Felipe de Jesús;Moreno-López, María Félix;García-Pérez, Faustino;Ramírez-Rojas, Sergio;Canul-Ku, Jaime;
Revista mexicana de ciencias agrícolas , 2012,
Abstract: in morelos, root rot caused by fusarium spp., is one of the main diseases of indoor poinsettia. in order to prevent or control its devastating effect, frequent applications of chemical products are performed, with inherent risks to human health and environment. in quest for alternative biorational options, an essay in which three commercial strains of trichoderma spp., was done, in three different substrates: s1= "organic soil" (70% v/v)+thick tezontle (15% v/v)+thin tezontle (10% v/v)+agrolita (5% v/v); s2= peat moss (80% v/v)+ coconut fiber (20% v/v); s3= "organic soil" (70%)+"tepojal" (30%), in most common commercial varieties, freedom red and prestige red. a factorial design of 4 x 3 x 2 treatment was used and resulting treatments were evaluated in a completely random design with six repetitions. regards root rot incidence, commercial strains of trichoderma spp., did not show differences between them, either with chemical control. root rot was associated with s2, due low aeration capacity, and only it was seen in prestige red. population of trichoderma spp.,(ufc g-1) in the substrate at end of cycle was the same (p< 0.05) between commercial strains and between them and the control (without inoculation), due presence of native strains of trichoderma in organic components of substrates ("organic soil", peat moss and coconut fiber).
Bevacizumab intravítreo seguido de láser focal en el edema macular diabético difuso de progresión reciente: Caso clínico
Moreno-López,M.; Regueras,A.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2009, DOI: 10.4321/S0365-66912009000400007
Abstract: case report: we report the case of a 48-year-old man with diffuse diabetic macular edema of recent progression treated with two consecutive intravitreal injections of bevacizumab followed by focal laser therapy, with good anatomic and functional response. discussion: diffuse diabetic macular edema is difficult to manage and frequently requires multiple therapies. we propose the use of bevacizumab as a strategy to reduce diffuse macular edema, facilitating the application of laser therapy.
Bevacizumab intravítreo seguido de láser focal en el edema macular diabético difuso de progresión reciente: Caso clínico Intravitreal bevacizumab followed by focal laser for diffuse diabetic macular edema of recent progression: A clinical case
M. Moreno-López,A. Regueras
Archivos de la Sociedad Espa?ola de Oftalmología , 2009,
Abstract: Caso clínico: Se presenta el caso de un varón de 48 a os de edad con edema macular diabético (EMD) difuso en su ojo derecho (OD) de reciente progresión, que es tratado con dos inyecciones intravítreas consecutivas de bevacizumab seguido de láser focal, mostrando buena respuesta funcional y anatómica. Discusión: El EMD difuso es de difícil manejo y con frecuencia precisa de multiterapias para su control. Proponemos el uso de bevacizumab intravítreo como coadyuvante para reducir el EMD difuso de progresión reciente, y facilitar la aplicación de fotocoagulación con láser. Case report: We report the case of a 48-year-old man with diffuse diabetic macular edema of recent progression treated with two consecutive intravitreal injections of bevacizumab followed by focal laser therapy, with good anatomic and functional response. Discussion: Diffuse diabetic macular edema is difficult to manage and frequently requires multiple therapies. We propose the use of bevacizumab as a strategy to reduce diffuse macular edema, facilitating the application of laser therapy.
Membrane-Derived Phospholipids Control Synaptic Neurotransmission and Plasticity
Victoria García-Morales?,Fernando Montero?,David González-Forero?,Guillermo Rodríguez-Bey?,Laura Gómez-Pérez?,María Jesús Medialdea-Wandossell?,Germán Domínguez-Vías?,José Manuel García-Verdugo?,Bernardo Moreno-López
PLOS Biology , 2015, DOI: 10.1371/journal.pbio.1002153
Abstract: Synaptic communication is a dynamic process that is key to the regulation of neuronal excitability and information processing in the brain. To date, however, the molecular signals controlling synaptic dynamics have been poorly understood. Membrane-derived bioactive phospholipids are potential candidates to control short-term tuning of synaptic signaling, a plastic event essential for information processing at both the cellular and neuronal network levels in the brain. Here, we showed that phospholipids affect excitatory and inhibitory neurotransmission by different degrees, loci, and mechanisms of action. Signaling triggered by lysophosphatidic acid (LPA) evoked rapid and reversible depression of excitatory and inhibitory postsynaptic currents. At excitatory synapses, LPA-induced depression depended on LPA1/Gαi/o-protein/phospholipase C/myosin light chain kinase cascade at the presynaptic site. LPA increased myosin light chain phosphorylation, which is known to trigger actomyosin contraction, and reduced the number of synaptic vesicles docked to active zones in excitatory boutons. At inhibitory synapses, postsynaptic LPA signaling led to dephosphorylation, and internalization of the GABAAγ2 subunit through the LPA1/Gα12/13-protein/RhoA/Rho kinase/calcineurin pathway. However, LPA-induced depression of GABAergic transmission was correlated with an endocytosis-independent reduction of GABAA receptors, possibly by GABAAγ2 dephosphorylation and subsequent increased lateral diffusion. Furthermore, endogenous LPA signaling, mainly via LPA1, mediated activity-dependent inhibitory depression in a model of experimental synaptic plasticity. Finally, LPA signaling, most likely restraining the excitatory drive incoming to motoneurons, regulated performance of motor output commands, a basic brain processing task. We propose that lysophospholipids serve as potential local messengers that tune synaptic strength to precedent activity of the neuron.
BVDV and BHV-1 Infections in Dairy Herds in Northern and Northeastern Thailand
J Kampa, K St?hl, J Moreno-López, A Chanlun, S Aiumlamai, S Alenius
Acta Veterinaria Scandinavica , 2004, DOI: 10.1186/1751-0147-45-181
Abstract: Based on our experiences and on these results we are convinced that this process can continue if there is awareness of herd biosecurity. This is especially important in the context of a future intensification of the dairy production.Bovine viral diarrhoea virus (BVDV) and bovine herpesvirus type 1 (BHV-1) are well-known, important pathogens of cattle that give rise to substantial economic losses due to reproductive failures and increased calf mortality, as well as enteric and respiratory disease. These pathogens have a worldwide distribution and tend to be endemic in most populations, although national and regional variations occur (for BVDV review see [21,14,18]; for BHV-1 review see [11,17,31]).Vaccination has been the conventional way to control or reduce losses caused by BVDV and BHV-1 for the last 4–5 decades [7,17]. The number of licensed vaccines on the market is vast and they are widely used. The use of vaccines may reduce economic losses caused by clinical disease, but does not appear to result in reduction of the prevalence of either BVDV or BHV-1 infections [34,25]. The introduction of gene-deleted vaccines was considered a breakthrough for the control of BHV-1 [31]. During 1998–1999 a live attenuated gE-deleted marker vaccine provided the basis for a compulsory control programme in the Netherlands. However, a severe outbreak of BVDV type 2 on several dairy farms, induced by contaminated gE-deleted marker vaccine, was a drawback that illustrated the potential risks with the use of live vaccines [3]. During the last decades eradication programmes against BVDV and BHV-1, without the use of vaccines, have been implemented in some European countries. These have been based on identification and elimination of carrier animals, together with increased herd biosecurity. The national BVD programmes in the Scandinavian countries, as well as the regional programmes in a few other countries in Europe, have had success with control of BVDV and are aiming towards eradi
Tratamiento quirúrgico conservador en un caso de quiste de iris postraumático
Moreno-López,M.; Arruabarrena,C.; Regueras,A.; Noval,S.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2007, DOI: 10.4321/S0365-66912007000700012
Abstract: case report: a 32-year-old man with recent visual loss in his right eye, was found to have an iris cyst involving about 50% of the anterior chamber. he had been treated three years previously for a penetrating injury to that eye. the cyst was treated by aspiration, viscodissection and ab-externo photocoagulation, with this achieving a rapid recovery of vision and good anatomic results. at the six month follow-up visit the visual acuity remains stable with no signs of recurrence of the cyst. discussion: conservative surgical treatment consisting of aspiration, viscodissection and photocoagulation appears to be an effective strategy to manage secondary anterior chamber cysts, achieving good anatomic and functional results.
Tratamiento quirúrgico conservador en un caso de quiste de iris postraumático Conservative surgical management of a post-traumatic iris cyst
M. Moreno-López,C. Arruabarrena,A. Regueras,S. Noval
Archivos de la Sociedad Espa?ola de Oftalmología , 2007,
Abstract: Caso clínico: Varón de 32 a os aquejado de pérdida visual en ojo derecho (OD) secundario a un quiste que ocupa la mitad de la cámara anterior, diagnosticado clínicamente de quiste secundario epitelial de iris. Tres a os antes había sufrido un traumatismo penetrante. Se realiza aspiración con aguja, viscodisección y fotocoagulación ab externo, logrando una rápida recuperación visual sin secuelas funcionales ni anatómicas. A los seis meses la agudeza visual permanece estable sin recidiva de la lesión. Discusión: El manejo quirúrgico conservador mediante aspiración y fotocoagulación en este caso fue eficaz y seguro en el tratamiento del quiste epitelial adquirido de iris. Case report: A 32-year-old man with recent visual loss in his right eye, was found to have an iris cyst involving about 50% of the anterior chamber. He had been treated three years previously for a penetrating injury to that eye. The cyst was treated by aspiration, viscodissection and ab-externo photocoagulation, with this achieving a rapid recovery of vision and good anatomic results. At the six month follow-up visit the visual acuity remains stable with no signs of recurrence of the cyst. Discussion: Conservative surgical treatment consisting of aspiration, viscodissection and photocoagulation appears to be an effective strategy to manage secondary anterior chamber cysts, achieving good anatomic and functional results.
Clinical Outcome of HIV-Infected Patients with Sustained Virologic Response to Antiretroviral Therapy: Long-Term Follow-Up of a Multicenter Cohort
Félix Gutierrez, Sergio Padilla, Mar Masiá, José A. Iribarren, Santiago Moreno, Pompeyo Viciana, Leopoldo Mu?oz, José L. Gómez Sirvent, Francesc Vidal, José López-Aldeguer, José R. Blanco, Manuel Leal, María Angeles Rodríguez-Arenas, Santiago Perez Hoyos
PLOS ONE , 2006, DOI: 10.1371/journal.pone.0000089
Abstract: Background Limited information exists on long-term prognosis of patients with sustained virologic response to antiretroviral therapy. We aimed to assess predictors of unfavorable clinical outcome in patients who maintain viral suppression with HAART. Methods Using data collected from ten clinic-based cohorts in Spain, we selected all antiretroviral-naive adults who initiated HAART and maintained plasma HIV-1 RNA levels <500 copies/mL throughout follow-up. Factors associated with disease progression were determined by Cox proportional-hazards models. Results Of 2,613 patients who started HAART, 757 fulfilled the inclusion criteria. 61% of them initiated a protease inhibitor-based HAART regimen, 29.7% a nonnucleoside reverse-transcriptase inhibitor-based regimen, and 7.8% a triple-nucleoside regimen. During 2,556 person-years of follow-up, 22 (2.9%) patients died (mortality rate 0.86 per 100 person-years), and 40 (5.3%) died or developed a new AIDS-defining event. The most common causes of death were neoplasias and liver failure. Mortality was independently associated with a CD4-T cell response <50 cells/L after 12 months of HAART (adjusted hazard ratio [AHR], 4.26 [95% confidence interval {CI}, 1.68–10.83]; P = .002), and age at initiation of HAART (AHR, 1.06 per year; 95% CI, 1.02–1.09; P = .001). Initial antiretroviral regimen chosen was not associated with different risk of clinical progression. Conclusions Patients with sustained virologic response on HAART have a low mortality rate over time. Long-term outcome of these patients is driven by immunologic response at the end of the first year of therapy and age at the time of HAART initiation, but not by the initial antiretroviral regimen selected.
Brain Structural Correlates of Reward Sensitivity and Impulsivity in Adolescents with Normal and Excess Weight
Laura Moreno-López, Carles Soriano-Mas, Elena Delgado-Rico, Jacqueline S. Rio-Valle, Antonio Verdejo-García
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0049185
Abstract: Introduction Neuroscience evidence suggests that adolescent obesity is linked to brain dysfunctions associated with enhanced reward and somatosensory processing and reduced impulse control during food processing. Comparatively less is known about the role of more stable brain structural measures and their link to personality traits and neuropsychological factors on the presentation of adolescent obesity. Here we aimed to investigate regional brain anatomy in adolescents with excess weight vs. lean controls. We also aimed to contrast the associations between brain structure and personality and cognitive measures in both groups. Methods Fifty-two adolescents (16 with normal weight and 36 with excess weight) were scanned using magnetic resonance imaging and completed the Sensitivity to Punishment and Sensitivity to Reward Questionnaire (SPSRQ), the UPPS-P scale, and the Stroop task. Voxel-based morphometry (VBM) was used to assess possible between-group differences in regional gray matter (GM) and to measure the putative differences in the way reward and punishment sensitivity, impulsivity and inhibitory control relate to regional GM volumes, which were analyzed using both region of interest (ROI) and whole brain analyses. The ROIs included areas involved in reward/somatosensory processing (striatum, somatosensory cortices) and motivation/impulse control (hippocampus, prefrontal cortex). Results Excess weight adolescents showed increased GM volume in the right hippocampus. Voxel-wise volumes of the second somatosensory cortex (SII) were correlated with reward sensitivity and positive urgency in lean controls, but this association was missed in excess weight adolescents. Moreover, Stroop performance correlated with dorsolateral prefrontal cortex volumes in controls but not in excess weight adolescents. Conclusion Adolescents with excess weight have structural abnormalities in brain regions associated with somatosensory processing and motivation.
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