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Search Results: 1 - 10 of 473902 matches for " María Emilia; Lantigua Cruz "
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Caracterización clínica del labio leporino con fisura palatina o sin ésta en Cuba
Roca Ortiz,. Joel Luis; Cendán Mu?iz,Isidro; Alonso Lotti,Francisca; Ferrero Oteiza,María Emilia; Lantigua Cruz,Aracely;
Revista Cubana de Pediatr?-a , 1998,
Abstract: 288 newborns with cleft lips with or without cleft palate, either associated or not to other types of defects, were detected among 8 004 malformed newborns included in the cuban birth defects register from april 1985 to december 1994. this defect alone was present in 77.4 % of cases whereas cleft palate was also present in two-thirds of cases. male newborns were predominant. left-hand anatomical defect location prevailed in both sexes. as to the associated defects, chromosomal syndromes accounting for 8 % were predominant from the pathogenic view point; in addition, the prevailing syndrome was trisomy 13 which was found in 21 cases.
El óxido nítrico en la nefrotoxicidad experimental por Ciclosporina A
De la Cruz Rodríguez,Lilia Cristina; Posleman,Sara Emilia; Araujo,Carmen Rosa; Rey,María Rosario;
Acta bioqu?-mica cl?-nica latinoamericana , 2005,
Abstract: the acute nephrotoxicity induced by cyclosporine a (cya) is characterized by a renal plasmatic flux decrease. the nitric oxide (no), which is a vasodilating factor, seems to be the explanation for nephrotoxicity by cya. the aim of this work is to evaluate the effect of no induced by l- arginine (l- arg) in experimental nephrotoxicity by cya. the studied population consisted on male rats divided into 4 groups (n = 8): a, b,c and d. groups a and b were treated with standard diet, and groups c and d were suplemented by 500 mg/kg of food of l-arg. groups b and d were treated with 0,1 ml of 50 mg/ml of cya solution during 7 days. the glomerular filtration was evaluated through serum creatinine and creatinine clearance. the serum creatinine of group d, treated with l-arg and cya, was significantly greater than in the other groups (p < 0.05). the creatinine clearance decreased in groups b and d (treated with cya). no was investigated by the excretion of urinary metabolites : nitrite + nitrate in 24 h urinary samples. the oxide nitric values were significantly greater in groups c and d, treated with l-arg (p < 0.05), but there were no significant differences of b in relation to a. anatomo-histological changes were evaluated. there was an increase kidney's size. hipotrophic renal parenchima and renal-tubule dilatation with cellular descamation were observed with histological methods. therefore: if cya has a vasoconstrictor effect on the afferent arteriole together with a decrease in the medular and cortical perfusion, the increase in the production of no provokes vasodilatation and induces to a severe renal injure which makes itself more powerful in the presence of cya that would increase the production of nitric oxide sintetase (nos) via inos mrna.
Respuesta inmune para la vacuna heberbiovac-hb y factores de riesgo Consolación del Sur, a?o 2004
Rieumont,Emilia Rosa; Martínez Gutiérrez,José Fco; Cruz Gónzalez,Tania; Lugo Rosa,María Gloria;
Revista de Ciencias M??dicas de Pinar del R?-o , 2009,
Abstract: one of the mainstays to control and eliminate hepatitis-b is the use of the vaccines (herberbiovac-hb) applied in cuba since 1992. the immunogenicity, an indicator obtained through the quantification of the antibodies titers (anti-hbs) against the surface antigens (hbsag) post-vaccination, allowing knowing the effectiveness and quality of the vaccine. the immunoenzymatic method was used in this study kind of sandwich (elisa), carried out by the department for the study of hepatitis b of the immunology laboratory in the national center of medical genetics, havana city. the individuals which results were between =10 ui/l and < 100 ui/l, hyperresponsers = 100 ui/l are considered protected and sero-unprotected when the titers were < 10 ui/l; in 498 children of 10 years old that were vaccinated in the early childhood having the schedule (0-16 months) of negative mothers for hbsag, belonging to consolacion del sur in pinar del rio province. results showed that male sex, hypersensibilities type i and the boys and girls maintaining treatments with immunosupresor drugs were the risk factors that provided the association with the serum-unprotection; as for in the individuals having titers of ac < 10 ui/l; a buster of the vaccine was applied and after 15 days the 100% of them achieved the values of serum-protection, calculating the geometric media to 35.1 ui/l before the reinforcement of the vaccine and after it 109.5 ui/l.
La Estadística Oficial como herramienta de aprendizaje en el aula Official Statistics as an educational resource L’Estadística Oficial com a ferramenta d’aprenentatge a l’aula
Emilia López I?esta,María Dolores Bolufer Costa,Francisco Grimaldo Moreno,Pablo de la Cruz Martínez
@tic : Revista d'Innovació Educativa , 2011, DOI: 10.7203/attic.7.294
Abstract: El presente trabajo muestra la importancia de la Estadística Oficial en la docencia de la Estadística. La Estadística Oficial puede usarse como una herramienta de gran utilidad en el contexto docente, ya que ofrece un elemento motivador para el aprendizaje tanto a nivel universitario como en la ense anza secundaria. A modo de ejemplo, se detalla una experiencia docente llevada a cabo durante el curso académico 2009/2010 en la que se hace un uso didáctico de la información de tres organismos oficiales: el Instituto Nacional de Estadística, el Instituto Valenciano de Estadística y la Oficina de Estadística del Ayuntamiento de Valencia. This paper deals with the important role that Official Statistics can play when teaching Statistics. Official Statistics can be used as a valuable teaching tool, as it offers a motivating learning approach for both university and high-school students. As a case of use, we describe a teaching experience carried out during the 2009-2010 academic year which uses as an educational resource the information coming from three official institutions: the Spanish National Statistics Institute, the Valencian Statistics Institute and the Statistics Office of the City Hall of Valencia. Aquest treball mostra la importància de l’Estadística Oficial en la docència de l’Estadística. L’Estadística Oficial pot esdevenir una ferramenta molt útil en el context docent, ja que ofereix un element encoratjador de l’aprenentatge tant a nivell universitari com en l’ensenyan a secundària. A mode d’exemple, detallem una experiència docent duta a terme en el curs acadèmic 2009/2010 en la qual es fa un ús didàctic de la informació de tres organismes Oficials: l’Institut Nacional d’Estadística, l’Institut Valencià d’Estadística i l’Oficina d’Estadística de l’Ajuntament de València.
El óxido nítrico en la nefrotoxicidad experimental por Ciclosporina A The nitric oxide in experimental nephrotoxicity induced by ciclosporine A
Lilia Cristina De la Cruz Rodríguez,Sara Emilia Posleman,Carmen Rosa Araujo,María Rosario Rey
Acta bioqu?-mica cl?-nica latinoamericana , 2005,
Abstract: La nefrotoxicidad aguda por Ciclosporina A (CyA) está caracterizada por la disminución del flujo plasmático renal. El óxido nítrico (NO), factor de vasodilatación, pareciera explicar la nefrotoxicidad por CyA. En este trabajo se estudia al NO inducido por L-Arginina (L- Arg) y su efecto en la nefrotoxicidad experimental por CyA. Se trabajó con ratas machos (Wistar) que fueron divididas en 4 grupos de 8 animales cada uno (n = 8): A, B, C y D. Los grupos A y B fueron alimentados con dietas estándares, los grupos C y D se suplementaron con 500 mg/kg de alimento de L-Arg. Los grupos B y D fueron tratados con 0,1 mL de CyA de una solución de 50 mg/mL durante 7 días. Se evaluó filtración glomerular determinando creatinina sérica y clearance de creatinina. Se investigó el NO por eliminación de sus metabolitos urinarios: nitritos + nitratos en orina de 24 h. La creatinina sérica del Grupo D, tratado con L-Arg y CyA, fue significativamente mayor respecto a los otros Grupos (p < 0,05). El clearance de creatinina decreció significativamente en los grupos tratados con CyA (B y D). Los valores hallados de nitritos + nitratos urinarios fueron significativamente mayores en los Grupos C y D tratados con L-Arg (p < 0,05), no encontrándose diferencias significativas de B respecto a A. En los grupos C y D se observó aumento de tama o de los ri ones de ratas; los cortes histológicos de los mismos estudiados con la técnica de Hematoxilina-Eosina mostraron un parénquima renal hipotrófico con franca vasodilatación de los túbulos de la zona medular y cortical y descamación celular con núcleos en la luz tubular renal. Se concluye que, si bien la CyA provoca un efecto vasocontrictor de la arteriola aferente, con disminución en la perfusión cortical y medular, el aumento en la producción de NO utilizando como precursor la L-Arg, provoca vasodilatación, a la vez que induce a un da o renal severo que se potencia con la presencia de CyA que aumentaría la producción de óxido Nítrico Sintetasa (NOS) vía iNOS mRNA. The acute nephrotoxicity induced by cyclosporine A (CyA) is characterized by a renal plasmatic flux decrease. The nitric oxide (NO), which is a vasodilating factor, seems to be the explanation for nephrotoxicity by CyA. The aim of this work is to evaluate the effect of NO induced by L- Arginine (L- Arg) in experimental nephrotoxicity by CyA. The studied population consisted on male rats divided into 4 groups (n = 8): A, B,C and D. Groups A and B were treated with standard diet, and groups C and D were suplemented by 500 mg/kg of food of L-Arg. Groups B and D were treated with
Efecto de trimetazidina en la nefrotoxicidad por gentamicina Trimetazidine effect on nephrotoxicity by gentamicyn
Lilia Cristina De la Cruz Rodríguez,María Rosario Rey,Ana Verónica Oldano,Sara Emilia Posleman
Acta bioqu?-mica cl?-nica latinoamericana , 2009,
Abstract: La Trimetazidina (TMZ) es una droga utilizada como cardioprotector, ya que previene la muerte celular secundaria a la isquemia miocárdica. Algunos investigadores le atribuyeron efecto reno-protector, actividad antioxidante y scavenger de radicales libres del oxígeno. El objetivo del presente trabajo es mostrar el efecto citoprotector de TMZ en las alteraciones inducidas por Gentamicina (G) a nivel de la célula del túbulo renal. Se dise aron esquemas en animales de experimentación tratados con ambas drogas. Ratas macho Wistar de 180 a 200 g de peso fueron distribuidas en 5 grupos (n=8) y tratadas con: dieta estándar (A); suplementada con 20 mg/Kg/día de TMZ durante 27 días (B); suplementada con 50 mg/Kg/día de G durante 7 días(C); pretratadas 20 días con 20 mg/Kg/día de TMZ y los últimos 7 días con G (D) y tratadas simultáneamente durante 7 días con 20 mg/Kg/día de TMZ y 50 mg/Kg/día de G(E). Se midieron los compuestos nitrogenados urea y creatinina, la excreción de gamma glutamiltranspeptidasa urinaria y se efectuaron estudios estructurales con tinción de hematoxilina-eosina y ultraestructurales. Se utilizó el grupo C como testigo de nefrotoxicidad inducida por G. El pretratamiento durante 20 días con TMZ demostró el efecto protector para la nefrotoxicidad inducida, sin cambios bioquímicos-funcionales, ni alteración de la histoarquitectura, ni de la ultraestructura. El tratamiento simultáneo con TMZ y G no mostró efecto protector. Se concluye que en el modelo de ratas macho Wistar se demuestra el efecto citoprotector de TMZ en tratamiento previo por 21 días. El estudio histológico del tejido renal, bajo estas condiciones, presenta histoarquitectura conservada y función renal normal. Se infiere que el efecto citoprotector de TMZ que impide la nefrotoxicidad inducida por G se debe a la inhibición de la reabsorción y acumulación de Gentamicina en la célula del túbulo proximal del nefrón. Trimetazidine (TMZ) is a drug used as a cardioprotector since it prevents cell death secondary to myocardial ischemia. Some investigators have attributed protective effect, antioxidant activity and oxygen free radical scavenging abilityt to TMZ. The aim of the present work is to show the cytoprotective effect of TMZ on Gentamicin (G)-induced alterations at the level of the renal tubular cell. Schemes were designed in experimental animals treated with both drugs. Male Wistar rats weighing 200 to 260 g were divided into 5 groups (n=8) and treated with: standard diet (A); standard diet supplemented with 20 mg/Kg/day of TMZ for 27 days (B); standard diet supplemented with 50 mg
Respuesta inmune para la vacuna heberbiovac-hb y factores de riesgo Consolación del Sur, a o 2004 Immnune response to the Heberbiovac-HB and risk factors, Consolación del Sur 2004
Emilia Rosa Rieumont,José Fco Martínez Gutiérrez,Tania Cruz Gónzalez,María Gloria Lugo Rosa
Revista de Ciencias M??dicas de Pinar del R?-o , 2009,
Abstract: Uno de los pilares fundamentales para el control, eliminación de la hepatitis tipo B es la utilización de la vacunas que se aplica en Cuba, desde el a o 1992. (Heberbiovac -HB). La inmunogenicidad, indicador que se obtiene mediante la cuantificación de Títulos de Anticuerpos (Anti-HBs) contra el antígeno de superficie (HBsAg) post vacunación permite conocer la eficacia y calidad de la vacuna. En este estudio se utilizó el método inmunoenzimático (ELISA) tipo sandwich, llevado a cabo por el Departamento de Hepatitis B. del Laboratorio de Inmunología del Centro Nacional de Genética Médica, Ciudad Habana, considerándose protegidos los individuos cuyos resultados estaban entre 310 UI/L y < 100 Ul/L, Hiperrespondedores 3 100 UI/L y No Seroprotegidos cuando los títulos eran < 10 UI/L; en 498 ni os de 10 a os que fueron vacunados en la infancia con esquema de (0-1-6 meses) hijos de madres negativas para el HBsAg, pertenecientes al Municipio Consolación del Sur en la Provincia de Pinar del Río, resultando que el género masculino, las Hipersensibilidades Tipo I y los ni os y ni as que mantuvieron tratamientos con drogas inmunosupresoras fueron los factores de riesgos que evidenciaron asociación con la no seroprotección; así como en los individuos que mostraron cifras de Títulos de Ac. < 10 UI/L; se aplicó un búster de la vacuna y pasados 15 días se obtuvo que el 100% de ellos alcanzaron valores de seroprotección, calculándose la media geométrica para 35.1 UI/L antes el refuerzo de la vacuna y después 109.5 UI/L. One of the mainstays to control and eliminate hepatitis-B is the use of the vaccines (Herberbiovac-HB) applied in Cuba since 1992. The immunogenicity, an indicator obtained through the quantification of the Antibodies Titers (Anti-HBs) against the surface antigens (HbsAg) post-vaccination, allowing knowing the effectiveness and quality of the vaccine. The immunoenzymatic method was used in this study kind of sandwich (ELISA), carried out by the Department for the study of Hepatitis B of the Immunology Laboratory in the National Center of Medical Genetics, Havana City. The individuals which results were between =10 UI/L and < 100 UI/L, Hyperresponsers = 100 UI/L are considered protected and sero-unprotected when the titers were < 10 UI/L; in 498 children of 10 years old that were vaccinated in the early childhood having the schedule (0-16 months) of negative mothers for HBsAg, belonging to Consolacion del Sur in Pinar del Rio province. Results showed that male sex, Hypersensibilities Type I and the boys and girls maintaining treatments with immunosupresor
Asociación de cistopatia eosinofilica con carcinoma transicional vesical infiltrante
Cruz Guerra,Nicolás Alberto; Chimeno Vi?as,María Montserrat; Ursúa Sarmiento,Inmaculada; Martínez Velado,Emilia; Valle Manteca,Alberto del;
Archivos Espa?oles de Urología (Ed. impresa) , 2009, DOI: 10.4321/S0004-06142009000900014
Abstract: objectives: to report a case of eosinophilc cystopathy associated to infiltrative transitional-cell carcino ma of the bladder in an adult. methods: we describe the case of a 79-year-old woman who complains of meso- and hipogastric pain since several months before, and to whom a parietal thickening of the bladder was detected by means of abdominal ct scan during the diagnostic work up for a digestive disease indicated by the internal medicine service. cistoscopy confirmed that finding, together with areas of greater endoluminal protrusion. cold biopsy showed an inflammatory in filtrate with eosinophilic component. transurethral resection was indicated. results: the pathological assessment was compatible with high-grade infiltrative transitional carcinoma of the bladder. the patient developed multiple lung metastases and died five months after surgery. conclusions: reports describing the coincidence of both entities are infrequent. we emphasize the importance of a correct filiation of apparently "pseudotumoral" endoluminal lesions.
Efecto de trimetazidina en la nefrotoxicidad por gentamicina
De la Cruz Rodríguez,Lilia Cristina; Rey,María Rosario; Oldano,Ana Verónica; Posleman,Sara Emilia; Araujo,Carmen Rosa;
Acta bioqu?-mica cl?-nica latinoamericana , 2009,
Abstract: trimetazidine (tmz) is a drug used as a cardioprotector since it prevents cell death secondary to myocardial ischemia. some investigators have attributed protective effect, antioxidant activity and oxygen free radical scavenging abilityt to tmz. the aim of the present work is to show the cytoprotective effect of tmz on gentamicin (g)-induced alterations at the level of the renal tubular cell. schemes were designed in experimental animals treated with both drugs. male wistar rats weighing 200 to 260 g were divided into 5 groups (n=8) and treated with: standard diet (a); standard diet supplemented with 20 mg/kg/day of tmz for 27 days (b); standard diet supplemented with 50 mg/kg/day of g for 7 days (c), pretreated for 20 days with 20 mg/kg/day of tmz and for the last 7 days with g (d), and treated simultaneously for 7 days with 20 mg/kg/day of tmz and 50 mg/kg/day of g (e). the nitrogen compounds urea and creatinine were measured and so was the excretion of urinary gamma-glutamyl transpeptidase. structural studies with hematoxilin and eosin staining and ultrastructural studies were also performed. gentamicin was used as a control for nephrotoxicity (group c). pretreatment with tmz showed a protective effect against induced nephrotoxicity, with no biochemical changes or alterations in the histoarchitecture. simultaneous treatment with tmz and g (group e) showed no protective effect. conclusions: the cytoprotective effect of tmz on g-induced nephrotoxicity would take place at the level of the proximal tubular cell of the brush border by inhibiting g reabsorption and accumulation.
El pedido de armas de Venus a Vulcano (En. 8. 370-406): algunos intertextos
Cairo,María Emilia;
Circe de cl??sicos y modernos , 2010,
Abstract: the aim of this paper is to study the episode of aeneid 8 in which venus asks vulcan to make an armour for aeneas. in particular, we are interested in investigating the intertextual relationships which it bears to four passages of the epic tradition: iliad 18, iliad 14, odyssey 8 and lucretius' proem to de rerum natura. the analysis of virgilian imitatio contributes to the study of the complexity of venus' character.
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