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Search Results: 1 - 10 of 562249 matches for " Manoel B. A. Neto "
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Description of the male of Mangora brokopondo (Araneae, Araneidae), with notes on Mangora species from Brazilian Oriental Amazon Descri o do macho de Mangora brokopondo (Araneae, Araneidae), com notas sobre espécies de Mangora da Amaz nia Oriental brasileira
Regiane Saturnino,Emanuel G. Cafofo,Manoel B. A. Neto,Janael Ricetti
Iheringia. Série Zoologia , 2013,
Abstract: The male of Mangora brokopondo Levi, 2007 is described and illustrated for the first time. Variation in the color pattern of the females is documented. Mangora woytkowskii Levi, 2007 is considered a junior synonym of M. hirtipes (Taczanowski, 1878). New records of M. alinahui Levi, 2007 and M. pia Chamberlin & Ivie, 1936 are presented. O macho de Mangora brokopondo Levi, 2007 é descrito e ilustrado pela primeira vez. Varia o no padr o de colora o da fêmea é documentada. Mangora woytkowskii Levi, 2007 é considerado sin nimo-júnior de M. hirtipes (Taczanowski, 1878). Novos registros de M. alinahui Levi, 2007 e M. pia Chamberlin & Ivie, 1936 s o apresentados.
Insecticidal activity of 2-tridecanone against the cowpea weevil Callosobruchus maculatus (Coleoptera: Bruchidae)
Braga, Yussef F.B.;Grangeiro, Thalles B.;Freire, Eder A.;Lopes, Helano L.;Bezerra, José N. S.;Andrade-Neto, Manoel;Lima, Mary Anne S.;
Anais da Academia Brasileira de Ciências , 2007, DOI: 10.1590/S0001-37652007000100005
Abstract: the effect of 2-tridecanone vapor on the cowpea weevil (callosobruchus maculatus) development was determined. seeds of cowpea were infested with adults and exposed to different doses of 2-tridecanone isolated from pilocarpus microphyllus stapf ex holm, a plant species native from northeastern brazil. the pure monoterpene was evaluated both undiluted as well as in the dilutions 1:10, 1:100 and 1:1,000 (v/v). the following parameters of the cowpea weevil life cycle were analyzed in response to decreasing doses of 2-tridecanone: number of eggs laid, percentage of egg hatching on seeds, percentage of adult emergence, adult weight at emergence, mean developmental time and number of adults emerged. vapor of 2-tridecanone caused a significant (p < 0.05) reduction in the number of eggs laid, in the percentage of eggs hatched and in the number of emerged adults in infested seeds. the fumigant insecticidal effect of 2-tridecanone was mainly due to its ovicidal activity.
Plasma Superoxide Dismutase-1 as a Surrogate Marker of Vivax Malaria Severity
Bruno B. Andrade,Antonio Reis-Filho,Sebasti?o Martins Souza-Neto,Imbroinise Raffaele-Netto,Luis M. A. Camargo,Aldina Barral,Manoel Barral-Netto
PLOS Neglected Tropical Diseases , 2010, DOI: 10.1371/journal.pntd.0000650
Abstract: Background Severe outcomes have been described for both Plasmodium falciparum and P. vivax infections. The identification of sensitive and reliable markers of disease severity is fundamental to improving patient care. An intense pro-inflammatory response with oxidative stress and production of reactive oxygen species is present in malaria. Inflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha) and antioxidant agents such as superoxide dismutase-1 (SOD-1) are likely candidate biomarkers for disease severity. Here we tested whether plasma levels of SOD-1 could serve as a biomarker of severe vivax malaria. Methodology/Principal Findings Plasma samples were obtained from residents of the Brazilian Amazon with a high risk for P. vivax transmission. Malaria diagnosis was made by both microscopy and nested PCR. A total of 219 individuals were enrolled: non-infected volunteers (n = 90) and individuals with vivax malaria: asymptomatic (n = 60), mild (n = 50) and severe infection (n = 19). SOD-1 was directly associated with parasitaemia, plasma creatinine and alanine amino-transaminase levels, while TNF-alpha correlated only with the later enzyme. The predictive power of SOD-1 and TNF-alpha levels was compared. SOD-1 protein levels were more effective at predicting vivax malaria severity than TNF-alpha. For discrimination of mild infection, elevated SOD-1 levels showed greater sensitivity than TNF-alpha (76% vs. 30% respectively; p<0.0001), with higher specificity (100% vs. 97%; p<0.0001). In predicting severe vivax malaria, SOD-1 levels exhibited higher sensitivity than TNF-alpha (80% vs. 56%, respectively; p<0.0001; likelihood ratio: 7.45 vs. 3.14; p<0.0001). Neither SOD-1 nor TNF-alpha could discriminate P. vivax infections from those caused by P. falciparum. Conclusion SOD-1 is a powerful predictor of disease severity in individuals with different clinical presentations of vivax malaria.
Cyclosporin safety in a simplified rat brain tumor implantation model
Felix, Francisco H. C.;Fontenele, Juvenia B.;Teles, Milena G.;Bezerra Neto, Jo?o E.;Santiago, Márcia H. A. M.;Pican?o Filho, Roberto L.;Menezes, Dalgimar B. de;Viana, Glauce S. B.;Moraes, Manoel O. de;
Arquivos de Neuro-Psiquiatria , 2012, DOI: 10.1590/S0004-282X2012000100011
Abstract: brain cancer is the second neurological cause of death. a simplified animal brain tumor model using w256 (carcinoma 256, walker) cell line was developed to permit the testing of novel treatment modalities. wistar rats had a cell tumor solution inoculated stereotactically in the basal ganglia (right subfrontal caudate). this model yielded tumor growth in 95% of the animals, and showed absence of extracranial metastasis and systemic infection. survival median was 10 days. estimated tumor volume was 17.08±6.7 mm3 on the 7th day and 67.25±19.8 mm3 on 9th day post-inoculation. doubling time was 24.25 h. tumor growth induced cachexia, but no hematological or biochemical alterations. this model behaved as an undifferentiated tumor and can be promising for studying tumor cell migration in the central nervous system. dexamethasone 3.0 mg/kg/day diminished significantly survival in this model. cyclosporine 10 mg/kg/day administration was safely tolerated.
ZSM5 as a Potential Catalyst for Glycerol Pyrolysis  [PDF]
Margarida L. Castelló, Jo Dweck, Donato A. G. Aranda, Rosana C. L. Pereira, Manoel J. R. Guimar?es Neto
Journal of Sustainable Bioenergy Systems (JSBS) , 2014, DOI: 10.4236/jsbs.2014.41006

Glycerol is a substance known to humankind for many years now, and among other products, in which composition it is used, are the pharmaceutical, cosmetic, food, paints and varnishes REF _Ref382993082 \r \h [1]REF _Ref382993086 \r \h [6]. The abundance of its supply leads to search for new uses, whether as a plasticizer for biodegradable polymers REF _Ref382993096 \r \h [7], its transformation into other substances like propylene and derivatives or other hydrocarbons [8] [9], the production of hydrogen for energy purposes REF _Ref382993109 \r \h [10], or even direct burning, making glycerol a fuel for boilers, for example. The aim of this work was to investigate the action of the zeolite ZSM5 on glycerol fast pyrolysis at 600°C. The tests were done with a

Hepatitis B Infection Is Associated with Asymptomatic Malaria in the Brazilian Amazon
Bruno B. Andrade,Cristiane J. N. Santos,Luís M. Camargo,Sebasti?o M. Souza-Neto,Antonio Reis-Filho,Jorge Clarêncio,Vitor R. R. Mendon?a,Nívea F. Luz,Erney P. Camargo,Aldina Barral,Ant?nio A. M. Silva,Manoel Barral-Netto
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0019841
Abstract: Areas that are endemic for malaria are also highly endemic for hepatitis B virus (HBV) infection. Nevertheless, it is unknown whether HBV infection modifies the clinical presentation of malaria. This study aimed to address this question.
Antifungal Activity of Naphthoquinoidal Compounds In Vitro against Fluconazole-Resistant Strains of Different Candida Species: A Special Emphasis on Mechanisms of Action on Candida tropicalis
Jo?o B. A. Neto, Cecília R. da Silva, Maria A. S. Neta, Rosana S. Campos, Janaína T. Siebra, Rose A. C. Silva, Danielle M. Gaspar, Hemerson I. F. Magalh?es, Manoel O. de Moraes, Marina D. P. Lobo, Thalles B. Grangeiro, Tatiane S. C. Carvalho, Emilay B. T. Diogo, Eufranio N. da Silva Júnior, Felipe A. R. Rodrigues, Bruno C. Cavalcanti, Hélio V. N. Júnior
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0093698
Abstract: In recent decades, the incidence of candidemia in tertiary hospitals worldwide has substantially increased. These infections are a major cause of morbidity and mortality; in addition, they prolong hospital stays and raise the costs associated with treatment. Studies have reported a significant increase in infections by non-albicans Candida species, especially C. tropicalis. The number of antifungal drugs on the market is small in comparison to the number of antibacterial agents available. The limited number of treatment options, coupled with the increasing frequency of cross-resistance, makes it necessary to develop new therapeutic strategies. The objective of this study was to evaluate and compare the antifungal activities of three semisynthetic naphthofuranquinone molecules against fluconazole-resistant Candida spp. strains. These results allowed to us to evaluate the antifungal effects of three naphthofuranquinones on fluconazole-resistant C. tropicalis. The toxicity of these compounds was manifested as increased intracellular ROS, which resulted in membrane damage and changes in cell size/granularity, mitochondrial membrane depolarization, and DNA damage (including oxidation and strand breakage). In conclusion, the tested naphthofuranquinones (compounds 1–3) exhibited in vitro cytotoxicity against fluconazole-resistant Candida spp. strains.
Jatropha seed oil content and yield under different irrigation and potassium fertilization levels
Deus, Fábio P. de;Faria, Manoel A. de;Oliveira, Ednaldo L. de;Castro Neto, Pedro;
Engenharia Agrícola , 2012, DOI: 10.1590/S0100-69162012000600010
Abstract: the aim of this research was to evaluate the effects of different irrigation depths and potassium dosages, of jatropha seed oil content and yield. the experimental design used was randomized blocks, in split-plots, with four replicates. the treatments were four water depths (plots) and four potassium dosages (subplots) applied through irrigation water. the water depths were applied based on the percentage of accumulated evaporation of a class a (eca) tank and of rainfall, as following: l0 = without irrigation, l40, l80 and l120, representing 40, 80 and 120% of the balance, respectively. the potassium dosages were k30, k60, k90 and k120 (30, 60, 90 and 120kg ha-1 of potassium, respectively). the oil extraction of samples was done through chemical extraction by organic solvent. the seeds used in this test were from the sampling of two seed productions from 2009, second year of crop production. it was possible to observe that irrigation use increased oil yield and decreased the oil content of jatropha seed. potassium fertilization did not influence oil content and yield. there was a relative increase of efficiency in water use producing oil until certain water depth, and after that there was a decrease.
Endoscopic approach to fourth ventricle cysticercosis
Zymberg, Samuel Tau;Paiva Neto, Manoel Antonio;Gorgulho, Alessandra A.P.;Cavalheiro, Sérgio;
Arquivos de Neuro-Psiquiatria , 2003, DOI: 10.1590/S0004-282X2003000200009
Abstract: neurocysticercosis is the most frequently observed parasitosis of the central nervous system worldwide. the fourth ventricle is the most frequent site of intraventricular infestation, a location that carries a higher risk for csf blockage and intracranial hypertension due to csf blockage. a great number of patients become shunt dependent which carries a poorer prognosis. we report on a case of a patient with symptomatic obstructive hydrocephalus due to cysticercus in the fourth ventricle where an endoscopic approach via a frontal burr hole was performed. although there is no consensus in the literature for the optimal treatment of this disease, this method seemed adequate for treatment of fourth ventricle cysticercosis in patients with hydrocephalus, aqueductal and foramen of monro dilatations.
Schwanoma intracerebral talamico: relato de caso
Andrade, Guilherme Cabral de;Paiva Neto, Manoel A. de;Braga, Fernando Menezes;
Arquivos de Neuro-Psiquiatria , 2002, DOI: 10.1590/S0004-282X2002000200025
Abstract: the intracranial schwannomas cover about 8% of all the brain tumors, although, those localized inside the encephalic parenchyma are rare only 55 cases being reported in the literature. the histhopatologic diagnosis is based on the cellular type and arrangement common to the nervous sheat tumors, the immunohistochemical findings (gfap, s-100 protein, ema) and electronmicroscopic findings as well. the clinical presentation related to the intraparenchimatous schwannoma is variable, depending on its localization, the image diagnosis does not show any typical aspect. the surgical treatment is curative once a complete extirpation is obtained. these tumors are benign but one case reported presented malignant signs. we present a patient that had a thalamic schwannoma with histological confirmation. we found no case with this localization in the literature.
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