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Distribution of Antimony in a Tropical Estuary Dominated by Mangroves  [PDF]
Sanjay K Mandal, Natasha Majumdar, Chumki Choudhury, Raghab Ray, Manab K Dutta, Tapan K Jana
Journal of Environmental Protection (JEP) , 2011, DOI: 10.4236/jep.2011.26095
Abstract: Seasonal variation of antimony was studied in order to characterize its distribution in estuarine water, pore water, sediment, and digenetic behavior in the Sundarbans mangrove ecosystem. The mean concentration of dissolved inorganic Sb ranged between 230.8 and 303.1 ng L–1 over the period of study with a minimum during the post-monsoon closely associated with spring diatom bloom. Molecular diffusion flux of Sb was found greater than its value advected and deposited on sediment-water interface and there was significant remobilization of Sb in the Sundarbans mangrove ecosystem.
STUDY ON ENDOCRINOLOGICAL PROFILE OF HIV INFECTED MALE PATIENTS FROM EASTERN INDIA
Mandal Sanjay K,Paul Rudrajit,Bandyopadhyay Dipanjan,Basu Asish K
International Research Journal of Pharmacy , 2013, DOI: 10.7897/2230-8407.04347
Abstract: Human Immunodeficiency virus (HIV) infectionis associated with a variety of endocrine problems. Hypoadrenalism, hypothyroidism and hypogonadism are commonly found singly or in combination. Especially, male hypogonadism is very common in this population and may lead to weight loss, lethargy and other co morbidities. We undertook this cross sectional observational study to evaluate endocrine profile in HIV infected males in a sample Eastern Indian population. We also studied for any correlation of the endocrine dysfunctions with their immune status. We studied the blood hormone profiles along with blood CD4 counts. The bloods were drawn in fasting state and analysed using suitable high sensitivity assays. Standard statistical methods were used. We had 48 patients in our study. Among them, 33% had hypogonadism, 20% had hypothyroidism and 15 patients had diabetes. The hypogonadism was mainly hypogonadotropic. In other studies across the globe also, hypogonadism in HIV positive males is found to be significant. Our diabetic patients were not on protease inhibitors. We found some patients who had multiple endocrine dysfunctions. HIV infection is often associated with endocrine abnormalities. This aspect of the disease must be addressed during routine care of these patients. Hormone replacement must be individualized and may be needed for prolonged periods.
Primary Actinomycosis Of The Gluteal Region
Das Debasish,Majumdar Saswati,Mandal Sanjay K,Ghoshal Aloke G
Indian Journal of Dermatology , 2003,
Abstract: Actinomycosis is an indolent, chronic infection caused by microaerophilic, gram positive, non- sporing, slender bacilli of the Actinomyces genus. Ore-facial, abdominal and thoracic locations of infection make up majority of clinical cases. Gluteal or locations of actinomycosis on extremities are rarities. We present here a typical case of actinomycosis of the right gluteal region, without disease in other parts of the body in a nineteen year old female who presented with a three year history of a slowly growing, film lump in the right gluteal region. This case is of interest as it presents the typical history of indolent disease, the characteristic clinical and histopathological findings, and repeated misdiagnosis as a case of tuberculoses.
Multiorgan involvement due to cytomegalovirus infection in AIDS
Majumder, Shounak;Mandal, Sanjay K.;Bandyopadhyay, Dipanjan;Chowdhury, Subhasis Roy;Chakraborty, Partha P.;K., Mitra;
Brazilian Journal of Infectious Diseases , 2007, DOI: 10.1590/S1413-86702007000100039
Abstract: cytomegalovirus (cmv) infection is a relatively late complication of aids. like other viruses contributing to co-morbidity of hiv infection, cytomegalovirus has the propensity to cause multiorgan involvement. we report the case of a 34-year-old seropositive man who presented with bilateral lower limb weakness and symptomatic pallor. he was already on antiretroviral drugs for a month prior to presentation. detailed clinical examination and laboratory investigations revealed cytomegalovirus polyradiculoneuropathy associated with bone marrow dysplasia. dysplasia of haematopoeitic cell lines occurs in 30% to 70% of hiv infected patients, and is often indistinguishable from myelodysplastic syndrome. however, in our case, the bone marrow picture reverted back to normal with treatment of the cmv infection, pointing to a possible role of cmv as the causative agent of bone marrow dysplasia. moreover, cmv has been incriminated as a pathogen producing the immune reconstitution inflammatory syndrome. the onset of the disease in our case one month after initiation of haart strongly raises the possibility of this being a case of cmv related iris. this is the first reported case where iris has presented with cmv polyradiculoneuropathy and bone marrow dysplasia. we would like to highlight that in today's era of hiv care, clinicians should be aware of the possibility of multiorgan involvement by cmv, for appropriate management of this disease in the background of aids.
Production of cellulase-free xylanase by Trichoderma reesei SAF3
Kar, Sanjay;Mandal, Asish;Mohapatra, Pradeep K. das;Mondal, Keshab C.;Pati, Bikash R.;
Brazilian Journal of Microbiology , 2006, DOI: 10.1590/S1517-83822006000400011
Abstract: a xylanase producing fungi has been isolated from soil and identified as trichoderma reesei saf3. maximum growth of the organism was found at 48 h under submerged condition in xylan containing enriched medium, whereas highest enzyme production (4.75u/ml) was recorded at 72 h. no detectable cellulase activity was noted during whole cultivation period. the partially purified enzyme hydrolyzed xylan into xylopentose and xylose. all these properties of xylanase highlighten its promising uses in industrial scale.
Clofazimine
Kumar Bhushan,Mandal Sanjay
Indian Journal of Dermatology, Venereology and Leprology , 1998,
Abstract:
Effectiveness of Bumetanide Infusion in Treatment of Generalized Edema and Congestive Heart Failure  [PDF]
Anil K. Mandal
Open Journal of Internal Medicine (OJIM) , 2014, DOI: 10.4236/ojim.2014.43012
Abstract: Generalized edema (anasarca) is common in nephrotic syndrome which rarely produces shortness of breath. Increased shortness of breath associated with rapid weight gain and generalized edema signify congestive heart failure (CHF). Loop diuretics consisting of furosemide (Lasix®), bumetanide (Bumex®), torsemide (Demadex®) or ethacrynic acid (Edecrin) are effective diuretics to treat anasarca. However, efficacy varies depending on the renal function. Loop diuretic given orally or by intravenous boluses produce good urine output but overall response in reducing edema or shortness of breath as in CHF is less than optimum. Although literature information is very limited, continuous bumetanide infusion for 72 to 96 hours is found to be very effective in producing subjective relief of shortness of breath as well as objective improvement such as reduction in brain natriuretic peptide in CHF and improved kidney function, so that diuresis is sustained even after discontinuation of the infusion. Decrease in kidney function and electrolytes and acid-base imbalance are common but they are reversible with prompt replacement therapy. They pose no threat to life.
Pathogenesis and Prevention of Progression of Chronic Kidney Disease  [PDF]
Anil K. Mandal
Open Journal of Internal Medicine (OJIM) , 2015, DOI: 10.4236/ojim.2015.53010
Abstract: This treatise of chronic kidney disease (CKD) describes association of hypertension, diabetes and congestive heart failure (CHF) with CKD. CKD is defined by estimated glomerular filtration rate (eGFR) of less than 60 ml/min for three months or more. CKD is generally irreversible but not necessarily progressive. Thus progression of CKD into end stage renal disease (ESRD) is the concern here and what can be done to reduce the progression of CKD. Exact data of CKD with progression are unavailable but high incidence of ESRD (dialysis) eleven times more in 2011 than in 1980 accordingly to United States (US) Renal Data System is a testimonial to progression of CKD in patients with diabetes, hypertension, CHF and other renal diseases. US Renal Data System reveals that ESRD has soared in parallel with marketing of angiotensin converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB) drugs, providing strong indirect evidence that these drugs are someway instrumental in the progression of CKD into ESRD. These drugs produce acute renal failure which is an independent risk factor for CKD. Thus shift in therapy with enthusiastic use of ACEI/ARB drugs has led to dialysis bonanza throughout the world benefiting the professionals and corporations at the expense of vegetative life of the patients associated with family and societal burdens. The ways to turn the pendulum is to treat diabetes with insulin and hypertension with beta blocker, calcium channel blocker and diuretic therapy, and avoid the use of ACEI/ARB drugs. It is important to understand that diuretic orally, by intravenous boluses or by continuous infusion, is the cornerstone of therapy for CHF, whereas ACEI/ARB drugs markedly impair the efficacy of diuretics by lowering the blood pressure to a very low level thereby reducing renal perfusion. An evidence for that is marked elevation of BUN with comparatively slight increase of serum creatinine. Thus with the approaches stated above, CKD is less likely to progress; hence rate of ESRD is likely to decrease.
Optimal Scheduling of Cascaded Hydrothermal Systems Using a New Improved Particle Swarm Optimization Technique  [PDF]
Kamal K. Mandal, Niladri Chakraborty
Smart Grid and Renewable Energy (SGRE) , 2011, DOI: 10.4236/sgre.2011.23032
Abstract: Optimum scheduling of hydrothermal plants generation is of great importance to electric utilities. Many evolutionary techniques such as particle swarm optimization, differential evolution have been applied to solve these problems and found to perform in a better way in comparison with conventional optimization methods. But often these methods converge to a sub-optimal solution prematurely. This paper presents a new improved particle swarm optimization technique called self-organizing hierarchical particle swarm optimization technique with time-varying acceleration coefficients (SOHPSO_TVAC) for solving short-term economic generation scheduling of hydrothermal systems to avoid premature convergence. A multi-reservoir cascaded hydrothermal system with nonlinear relationship between water discharge rate, power generation and net head is considered here. The performance of the proposed method is demonstrated on two test systems comprising of hydro and thermal units. The results obtained by the proposed methods are compared with other methods. The results show that the proposed technique is capable of producing better results.
Integral Φ0-Stability of Impulsive Differential Equations  [PDF]
Anju Sood, Sanjay K. Srivastava
Open Journal of Applied Sciences (OJAppS) , 2015, DOI: 10.4236/ojapps.2015.510064
Abstract: In this paper, the notions of integral Φ0-stability of ordinary impulsive differential equations are introduced. The definition of integral Φ0-stability depends significantly on the fixed time impulses. Sufficient conditions for integral Φ0-stability are obtained by using comparison principle and piecewise continuous cone valued Lyapunov functions. A new comparison lemma, connecting the solutions of given impulsive differential system to the solution of a vector valued impulsive differential system is also established.
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