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Search Results: 1 - 10 of 50537 matches for " Mamatha. Y "
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Rare Variant Origin of Right Testicular Artery - A Case Report
Y Mamatha, BS Prakash, K Padmalatha
Asian Journal of Medical Sciences , 2011, DOI: 10.3126/ajms.v2i1.3860
Abstract: Variations in the origin of arteries in the abdomen are very common but with the invention of new operative techniques within the abdomen cavity, the anatomy of abdomen vessels has assumed much more clinical importance. The gonadal arteries normally arise caudal to the renal arteries as antero-lateral branch. In contrast to classical description, very rarely originate from lumbar, common or internal iliac artery, or superior mesentric artery. Here we report a very rare case of variant origin of right testicular artery from right common iliac artery. Awareness of such variations becomes very significant and important during surgical or interventional procedures in abdomen-pelvic areas.
Left arteriae vertebralis canal in atlas – Kimmerle anomaly
Prakash BS,Latha PK,Mamatha Y,Ramesh BR
International Journal of Anatomical Variations , 2010,
Abstract: Atlas, the ring form of vertebra bears sulcus over posterior arch for third part of vertebral artery. We report a case of presence of osseous bridge on the left side of human atlas, connecting posterior part of superior articular process to the posterior arch of atlas. Sulcus vertebrae for third part of vertebral artery over superior aspect of posterior arch of atlas, converted into foramen. Also considered as ponticulus posterior of the atlas, an anatomic variant – is a retrogressive and morphological phenomenon considered as Kimmerle anomaly. Complete ossification of ligamentous free margin of posterior atlanto-occipital membrane can lead to complete arcuate foramen. Knowledge of this variant prevents complication during lateral mass screw fixation, posterior laminectomy, endovascular surgery.
Variant course of left gonadal artery
Mamatha Y,Prakash BS,Latha PK,Ramesh BR
International Journal of Anatomical Variations , 2010,
Abstract: The variations of the arteries that develop from the mesonephric arteries, including renal, gonadal and suprarenal arteries are common. Variations in the anatomical relationship of the gonadal arteries to the renal vessels are frequently reported. We here present a case of an unusual origin and course of a left testicular artery arching over left renal vein. The arching of the left testicular artery over the left renal vein could be a possible cause of the left renal vein compression. Therefore, knowledge of the possible existence of arching gonadal vessels in relation to the renal vein could be of paramount importance to vascular surgeons and urologists during surgery in the retroperitoneal region.
Feature Extraction from Rural Satellite Imagery Using Color Based CBIR Techniques
Mamatha Y.N,A.G..Ananth
International Journal of Software Engineering & Applications , 2011,
Abstract: The ability to organize and retrieve visual information such as images is becoming a crucial problem forspecialists, because processing visual information requires perceptual abilities not yet known to exist incomputational form. Therefore the ability to retrieve visual information is a complex problem. The mainretrieval pattern include the features of an image such as colour, and shape. The algorithms used tocalculate the similarity between extracted feature with an image database, that utilizes colour featuresof the images as the basis of comparison and retrieval. An object-oriented definition also involvesprescribing a set of pertinent features or pixels as well as a method such as a classification algorithmwith the appropriate training data. A low resolution satellite image of a rural scenario has been selectedfor the analysis. The entire image scene is divided into four equal quadrants. The Content-basedretrieval of image features have been carried out for the selected two quadrants I and II. The colorclassification of the image in two quadrants clearly indicates that there are four important features thatare common to the images1 The features identified include, Natural Vegetation, Water Bodies, Land,and Housing associated with the image. Further using the L*a*b color spectral distribution andhistogram techniques an estimation of the different features identified in the image has been made for allthe four quadrants. The results are presented in the paper.
Network Security for MANETS
Mamatha. T
International Journal of Soft Computing & Engineering , 2012,
Abstract: A mobile ad hoc network (MANET) is a network consisting of a collection of nodes capable of communicating with each other without the help from a network infrastructure. Although security issues in mobile ad hoc networks have been a major focus in the recent years, the development of fully secure schemes for these networks has not been entirely achieved till now. MANETs have a unique characteristics and constraints that make traditional approaches to security inadequate. The lack of an infrastructure exacerbates the situation of using shared secret keys or authentication among members. Therefore, the issues of authentication, key distribution and intrusion detection require different methods, which are discussed here. In this paper, we propose to combine efficient techniques from elliptic curve cryptography (ECC) and a distributed intrusion detection system (IDS) based on threshold cryptography. And also propose to use a distributed certifying authority (CA) along with per-packet per-hop authentication for addressing the issues mentioned above. The model assumes that no single node can be trusted and relies instead on a distributed trust model.
BUCCAL DRUG DELIVER Y A TECHNICAL APPROACH
Mamatha. Y,Prasanth V.V,Selvi Arunkumar,Sipai Altaf Bhai. M
Journal of Drug Delivery and Therapeutics , 2012,
Abstract: Over the last few years Pharmaceutical scientists are trying to explore transdermal and transmucosal routes as an alternative to injections. Buccal delivery of the desired drug using mucoadhesive polymers has been the subject of interest since the early 1980s. Conventional dosage forms for delivery of drugs via the oral mucosa include solutions, erodible or chewable, buccal or sublingual tablets and capsules. Unfortunately, a major portion of the drug in these systems may be unavailable due to involuntary swallowing and a very short residence time, because of mastication, speech etc and hence sustained release is usually not within the scope of such Formulations and development of Novel bioadhesive dosage forms for mucosal delivery of drugs that attempt to overcome these limitations. We formulated buccal drug delivery, the buccal cavity was found to be the most convenient and easily accessible site for the delivery of therapeutic agents for both local and systemic delivery as retentive dosage forms. Because buccal Adhesive drug delivery system prolong the residence time of the dosage form at the site of application or absorption and facilitate an intimate contact of the dosage form with the limited absorption surface and thus contribute to improved better therapeutic efficacy of the drug. Buccal administration of drugs provides a convenient route of administration for both systemic and local drug actions. Buccal drug delivery has gained significant attention and momentum since it offers remarkable advantages. This review article is an overview of buccal drug delivery systems encompassing a review of oral mucosa, active ingredient delivered via buccal route by different mucoadhesive formulations. Including, commercial technologies and future prospects of this route of drug delivery are discussed.
The Immunomodulatory Role of Calf Thymus Extract on Humoral and Cell Mediated Immune Response in Chicken Vaccinated Against New Castle Disease Virus
B.M. Chandra Naik,Y. Hari Babu,G.S. Mamatha
International Journal of Poultry Science , 2005,
Abstract: The effect of administration of calf thymus extract (CTE) with protein concentration of 1.8mg/ml was studied using two groups of day old layer chicks. Both the groups were vaccinated with ‘F’ and ‘R2B’ strains of New Castle Disease Virus (NDV) vaccines on 7th day and 8th week respectively. One group was administered with 1.8mg of thymic proteins intraperitoneally, one week prior and one week after each vaccination. The other group remained as vaccinated control group. Humoral and cell mediated responses were evaluated 15 days after each vaccination. Intraperitoneal administration of calf thymus extract markedly and significantly increased the antibody titres against NDV, serum globulin level, and percentage of lymphocytes in the blood. In addition thymus extract resulted in definite and significant cellular immunopotentiation.
TRANSDERMAL DRUG DELIVERY: A TECHNICAL WRITEUP
Vandana Yadav,Sipai Altaf Bhai. M,Mamatha. Y,Prasanth V.V
Journal of Pharmaceutical and Scientific Innovation , 2012,
Abstract: Transdermal drug delivery is another system which provides controlled and continuous delivery of the drug through the skin into the systemic circulation. Topical application which involves drug transport to viable epidermal and/or dermal tissues of the skin for local therapeutic effect while a very major fraction of drug is transported into the systemic blood circulation. Transdermal route provides many advantages over conventional oral and invasive methods of drug delivery such as avoids first pass metabolism, improve patient compliance, maintance steady state plasma concentration. This article provides an overview of skin permeation pathways, types of transdermal drug delivery system, methods of preparation with different methods of evaluation, and the recent advancement in transdermal drug delivery, which includes Transfersomes, Magnetophoresis, Controlled Heat Aided Drug Delivery System, Laser Radiation, Medicated Tattoos, Laser radiation.
LIPOSOMES: AN OVERVIEW
Sipai Altaf Bhai. M,Vandana Yadav,Mamatha. Y,Prasanth V.V
Journal of Pharmaceutical and Scientific Innovation , 2012,
Abstract: Drug development technologies constituting innovations at the formulation end in the Pharmaceutical industry has received a lot of attention in past two decades. Drug delivery as an opportunity to extend product life cycles has indeed proved its place in the market with significant advantages of therapeutic gains as well as commercial success. Carrier technology offers an intelligent approach for drug delivery by coupling the drug to a carrier particle such as liposomes, microspheres, nanoparticles, etc. which modulates the release and absorption characteristics of the drug. Liposomes are well known to alter the bio distribution of entrapped substances by protecting the enclosed material. They are widely used as vehicles to target the specific molecule to specific organ. During the last few decades liposomes have attracted great interest as ideal models for biological membranes as well as efficient carriers for drugs, diagnostics, vaccines, nutrients and other bioactive agents. Many techniques and methodologies have involved for the manufacture of liposomes, on small and large scales, since their introduction to the scientific community around 40 years ago. This article intends to provide an overview of the advantages and disadvantages of liposome preparation methods,their stability, bio distribution and their uses as drug delivery systems. The conventional method of preparing liposomes is basically for the multilamellar vesicles (MLVs). However, other methods are used to reduce the size of these MLVs to small unilamellar vesicles (SUVs) so as to increase their plasma lifetime and consequently increase the possibility of achieving greater tissue localisation. Some of these methods of size reduction are sonication and high pressure extrusion. Each of these methods has its own advantages and disadvantages. Large unilamellar vesicles (LUVs), on the other hand, are prepared mainly by detergent removal method and reverse phase extrusion technique. There are also improved pharmacokinetic properties with liposomal drugs compared to free drugs, though some formulation factors affect the release kinetics of the liposomal drugs. The review also shows that liposomes have a lot of biomedical applications and uses. They have been used in drug targeting, oral delivery of vaccines, insulin, peptides and some compounds, which are usually degraded in the gastrointestinal tract. It has also found application in topical therapy especially in the eye and lungs. Other areas of application are in cancer chemotherapy and treatment of human immunovirus (HIV) infection.
Massive Levemir (Long-Acting) Insulin Overdose: Case Report
Mamatha Oduru,Mahmood Ahmad
Case Reports in Medicine , 2012, DOI: 10.1155/2012/904841
Abstract: A 52-year-old insulin-dependant diabetic man presented to the Emergency Department 2 hours after a deliberate massive overdose of 2100 units of long-acting Levemir insulin and a large quantity of whisky. On initial assessment, his GCS was 3/15 and his capillary blood sugar was 2.6 mmol/L. The patient was given a 50 ml bolus of 50% dextrose, followed by intravenous infusions of both 5% and 10% dextrose. Despite the continuous infusions, he experienced 4 symptomatic hypoglycaemic episodes in the first 12 hours after admission. These were managed with oral glucose, IM glucagon, and further dextrose boluses. Blood electrolytes and pH were monitored throughout. Insulin overdoses are relatively common and often occur with an excess of other drugs or alcohol which can enhance its action. Overdoses can result in persistent hypoglycaemia, liver enzyme derangement, electrolyte abnormalities, and neurological damage. Overall mortality is 2.7% with prognosis poorest in patients who are admitted with decreased Glasgow Coma scale (GCS) 12 hours after overdose.
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