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Search Results: 1 - 10 of 298779 matches for " Maldonado Júnior "
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Changes on Schistosoma mansoni (Digenea: Schistosomatidae) worm load in Nectomys squamipes (Rodentia: Sigmodontinae) concurrently infected with Echinostoma paraensei (Digenea: Echinostomatidae)
Maldonado Júnior, Arnaldo;Coura, Renata;Garcia, Juberlan da Silva;Lanfredi, Reinalda Marisa;Rey, Luis;
Memórias do Instituto Oswaldo Cruz , 2001, DOI: 10.1590/S0074-02762001000900030
Abstract: the water rat, nectomys squamipes, closely involved in schistosomiasis transmission in brazil, has been found naturally infected simultaneously by schistosoma mansoni and echinostoma paraensei. laboratory experiments were conducted to verify parasitic interaction in concurrent infection. it was replicated four times with a total of 42 water rats and essayed two times with 90 mice pre-infected with e. paraensei. rodents were divided into three groups in each replication. a wild strain recently isolated from sumidouro, rj, and a laboratory strain of s. mansoni from belo horizonte (bh) was used. rats infected with e. paraensei were challenged 4 weeks later with s. mansoni and mice 2 or 6 weeks after the infection with s. mansoni. necropsy took place 8 weeks following s. mansoni infection. the n. squamipes treatment groups challenged with s. mansoni rj strain showed a significant decrease (80 and 65%) in the s. mansoni parasite load when compared with their respective control groups. there was a significant change or no change in the hosts challenged with the bh strain. the persistence time of e. paraensei within host was extended in relation to control groups, with a consequent enhancement of the number of recovered worm. an e. paraensei strain-specific influence on s. mansoni parasitism is reported. this paper presents some experimental data about this interaction in n. squamipes and mus musculus.
HPLC assay of lidocaine in in vitro dissolution test of the Poloxamer 407 gels
Ricci Júnior, Eduardo;Bentley, Maria Vitória Lopes Badra;Marchetti, Juliana Maldonado;
Revista Brasileira de Ciências Farmacêuticas , 2002, DOI: 10.1590/S1516-93322002000100011
Abstract: a simple high performance liquid chromatography method to assay lidocaine hydrochloride in aqueous receiving media, following in vitro release, is presented. lidocaine hydrochloride was analysed using a 5 mm lichrocart? rp-18 column (125 x 4 mm i.d.). the mobile phase was acetonitrile: 0.05 m sodium phosphate buffer, ph 6.0 (35:65) and 0.05% of diethylamine at a flow rate of 1 ml/min. the retention time was 7.9 min. detection was carried out at 210 nm at room temperature (28 oc). the method was found to be linear in the range 1.25 to 25 mg/ml, showing average intraassay and inter-assay coefficients of variation below 3.5%. the proposed method was validated for linearity, specificity, precision and accuracy and was shown to be useful for the analysis of lidocaine hydrochloride in in vitro release studies.
Changes on Schistosoma mansoni (Digenea: Schistosomatidae) worm load in Nectomys squamipes (Rodentia: Sigmodontinae) concurrently infected with Echinostoma paraensei (Digenea: Echinostomatidae)
Maldonado Júnior Arnaldo,Coura Renata,Garcia Juberlan da Silva,Lanfredi Reinalda Marisa
Memórias do Instituto Oswaldo Cruz , 2001,
Abstract: The water rat, Nectomys squamipes, closely involved in schistosomiasis transmission in Brazil, has been found naturally infected simultaneously by Schistosoma mansoni and Echinostoma paraensei. Laboratory experiments were conducted to verify parasitic interaction in concurrent infection. It was replicated four times with a total of 42 water rats and essayed two times with 90 mice pre-infected with E. paraensei. Rodents were divided into three groups in each replication. A wild strain recently isolated from Sumidouro, RJ, and a laboratory strain of S. mansoni from Belo Horizonte (BH) was used. Rats infected with E. paraensei were challenged 4 weeks later with S. mansoni and mice 2 or 6 weeks after the infection with S. mansoni. Necropsy took place 8 weeks following S. mansoni infection. The N. squamipes treatment groups challenged with S. mansoni RJ strain showed a significant decrease (80 and 65%) in the S. mansoni parasite load when compared with their respective control groups. There was a significant change or no change in the hosts challenged with the BH strain. The persistence time of E. paraensei within host was extended in relation to control groups, with a consequent enhancement of the number of recovered worm. An E. paraensei strain-specific influence on S. mansoni parasitism is reported. This paper presents some experimental data about this interaction in N. squamipes and Mus musculus.
Origem das controvérsias sobre os analgésicos após a ativa o dos aparelhos ortod nticos: ácido acetilsalicílico ou acetaminofeno? Sources of controversies over analgesics prescribed after activation of orthodontic appliances: acetylsalicylic acid or acetaminophen?
Alberto Consolaro,Vanessa Bernardini Maldonado,Milton Santamaria Júnior,Maria Fernanda M-O. Consolaro
Dental Press Journal of Orthodontics , 2010, DOI: 10.1590/s2176-94512010000100003
Abstract:
Regularidades empíricas de la estructura industrial mexicana: Evidencia de la Ley de Zipf
Francisco Javier Benita Maldonado,Júnior Alfredo Martínez Herández
Investigación y Ciencia de la Universidad Autónoma de Aguascalientes , 2011,
Abstract: Recientemente han sido encontrados, en el ámbito de las ciencias sociales, una gran cantidad de patrones y regularidades empíricas tradicionalmente asociadas con las ciencias naturales. Particularmente, en la ciencia económica, se ha encontrado evidencia empírica en torno a la existencia de fenómenos económicos gobernados por un tipo de regularidad conocida como Ley de Potencia. Fenómenos de agregación económica, como la distribución del ingreso y la riqueza, el crecimiento de las ciudades, los retornos de activos financieros y los volúmenes de transacción bursátiles, están especialmente condicionados por una Ley de Potencia en particular, llamada Ley de Zipf. Este artículo presenta evidencia empírica suficiente para afirmar la vigencia de la Ley de Zipf para el caso de la estructura industrial en México. Utilizando la clasificación del SCIAN, se analiza la estructura de 21 subsectores industriales. Mediante el uso de cuatro métodos se encuentra que el exponente de potencia tiende a su valor teórico esperado.
Ultrasound Determination of Gestational Age Using Placental Thickness in Female Dogs: An Experimental Study
André Luiz Louzada Maldonado,Edward Araujo Júnior,Débora Sartori Mendon?a,Luciano Marcondes Machado Nardozza,Antonio Fernandes Moron,Sérgio Aron Ajzen
Veterinary Medicine International , 2012, DOI: 10.1155/2012/850867
Abstract: Objective. To verify if the placental thickness allows determining the gestational age, evaluating the correlation between the referred gestational age with the studied one, and the accuracy of the placental thickness measurement (biometry) with fetal morphologic parameters in bitches. Methods. The placental thickness of 336 bitches of diverse breeds was evaluated. Bitches were divided in three groups by body weight: small, medium, and big large size. The gestations pregnancies were evaluated by ultrasound from the third week of gestation. An analysis was performed between the mean values of the gestational age obtained of placental thickness by adjustment of curves and the reported gestational age. Student's t-test was applied to compare the mean of reported and placental thickness gestational age. Significance was defined as . Results. A positive and statistically significant correlation exists between the placental thickness and gestational age. The expression that presents the best correlation coefficient and explanation was thickness of placenta = 0.021 gestational age ?0.314. Conclusion. It is possible to determine the gestational age in relation to the placental thickness measured by ultrasound in bitches with a satisfactory accuracy in relation to fetal morphologic parameters as gestational vesicle, ribs, or kidneys. 1. Introduction Ultrasound in veterinary medicine contributes to the diagnosis of several diseases in both small and large size animals [1, 2]. The major advantage of the ultrasound examination is the possibility of evaluating the internal architecture and the structure of the parenchyma of abdominal organs. Ultrasound is the best method for the diagnosis of pregnancy and for the evaluation of fetal viability. In addition, it is the most sensitive and specific method in the evaluation of gestational age [3, 4]. Although there are numerous works correlating the size and the gestational age by mathematic formulas based on biparietal and abdominal diameters and on the size of the gestational sac, the simplest way to the determine the approximate age of the fetus is by observing the presence of some anatomic structures [5, 6]. However, these studies do not make reference to the measurement of the placenta as a method for the determination of gestational age. The placenta is the first fetal organ to develop and has primordial and critical functions. It mediates implantation and establishes an interface for the exchange of nutrients and gas in the maternal-fetal circulation, affecting the local immunological mediators, the maternal
Biosilicate? Ototoxicity and Vestibulotoxicity evaluation in guinea-pigs
Massuda, Eduardo Tanaka;Maldonado, Lucas Lisboa;Lima Júnior, Jessé Teixeira de;Peitl, Oscar;Hyppolito, Miguel ?ngelo;Oliveira, José Antonio Apparecido de;
Brazilian Journal of Otorhinolaryngology , 2009, DOI: 10.1590/S1808-86942009000500009
Abstract: changes, destructions and interruptions in middle ear ossicular chain architecture may be caused by infection, trauma, tumors, congenital alterations or prior surgeries. nonetheless, infectious and inflammatory processes, focal or generalized which affect the middle ear are the most prevalent, causing a great demand for ossiculoplasty. biosilicato? is a new material which can be used in the middle ear with the goal of reconstructing the ossicular chain. it is a bioactive type a vitroceramic, in other words, it binds to bone or soft tissue in a matter of a few hours, thanks to the formation of hydroxy-carbonateapatatie in its contact surface when in contact with body fluids. aims: the goal of the present paper is to assess biosilicate ototoxicity and vestibular toxicity in experimental animals, for later use in humans. materials and methods: this a clinical and experimental study in which otoacoustic emissions were performed before and after the placement of biosilicate in the middle ear of experimental animals and a scanning electron microscopy was carried out in the cochlea, saccule, utriculus and macula of the semicircular canals after 30 and 90 days to assess oto and vestibular toxicity. results: there were no signs of oto or vestibular toxicity in any of the groups associated with biosilicate. conclusion: biosilicate is a safe material to be used in ossiculoplasties
Anestesia em paciente com Síndrome de Jó (hiper IgE): Relato de caso
Resende, Marco Ant?nio Cardoso de;Pantoja, Alberto Vieira;Charruff, Ilda Antunes Lopes Maldonado;Magalh?es Júnior, Nisval de;Luz, Priscilla;
Revista Brasileira de Anestesiologia , 2011, DOI: 10.1590/S0034-70942011000100009
Abstract: background and objectives: job's syndrome (js), one of the presentations of the hyper ige syndrome, is a rare immunodeficiency. it includes cutaneous abscesses, recurring pneumonias, pneumatoceles, eosinophilia, hyperimmunoglobulinemia e (> 2,000 iu.ml-1), and craniofacial and bone growth changes. this report describes the disease and its anesthetic management. case report: the patient is a 13 year old black male, 40 kg, asa ii, with job's syndrome diagnosed 6 months prior to this admission. the patient was admitted for elongation of the right femur. he denied use of drugs and prior surgeries; he presented good cervical mobility, interincisive distance greater than 3 cm, mallampati ii, without signs of infection. preoperative exams were within normal limits. he was monitored with electrocardioscope, spo2, non-invasive blood pressure, and petco2. after pre-oxygenation, general anesthesia was induced and he was maintained with sevoflurane. at the end of the procedure, the patient was extubated after reversal of the neuromuscular blockade, and the patient was transferred to the pacu with aldrete 9, he was discharged from the hospital 72 hours later, without complications. conclusions: the choice of anesthetic technique is guided by rigorous observation among risks and benefits for each patient, according to respiratory sequelae, risk of infection, and surgical site. in the patient described here, we considered that neuroaxis anesthesia could be associated with an increased risk of severe infections due to the patient immunologic background. the procedure was safely performed with general anesthesia.
Diversidade genética entre genótipos comerciais de maracujazeiro-amarelo (Passiflora edulis f. flavicarpa) e entre espécies de passifloras nativas determinada por marcadores rapd
Viana, Alexandre Pio;Pereira, Telma Nair Santana;Pereira, Messias Gonzaga;Souza, Margarete Magalh?es de;Maldonado, José Francisco Martinez;Amaral Júnior, Ant?nio Teixeira do;
Revista Brasileira de Fruticultura , 2003, DOI: 10.1590/S0100-29452003000300032
Abstract: the genetic variability among yellow passion fruit genotypes was evaluated using rapd as genetic markers of dna. for that, genetic materials were collected in commercial populations from traditional production fields of the north fluminense (itaperuna, s?o francisco do itabapoana, campos of goytacazes, rj-brazil). the diversity among the cultivated species passiflora edulis f. flavicarpa deg. and species related p. alata, p. giberti, p. cincinnata, p. foetida, p. edulis. p. maliformis, p. mucronata, p. suberosa, p. malacophylla, was also estimated. for the study on yellow passion fruit, expressive genetic diversity was not verified; the populations were distributed according to its origin, and the individuals collected in s?o francisco do itabapoana presented major consistency in its grouping, once the formation of the groups a larger number of those individuals were allocated among the same group. for the interspecific study, it was verified that p. maliformis was in a different, but close group to p. mucronata. p. alata was allocated in an isolated group as well as p. giberti. for p. cincinnata and p. edulis (purple passion fruit), both were allocated in the same group, evidencing proximity between the same ones while p. foetida and p. suberosa formed a single group.
First report of Angiostrongylus cantonensis (Nematoda: Metastrongylidae) in Achatina fulica (Mollusca: Gastropoda) from Southeast and South Brazil
Maldonado Júnior, Arnaldo;Sim?es, Raquel O;Oliveira, Ana Paula M;Motta, Esther M;Fernandez, M?nica A;Pereira, Zilene M;Monteiro, Simone S;Torres, Eduardo J Lopes;Thiengo, Silvana Carvalho;
Memórias do Instituto Oswaldo Cruz , 2010, DOI: 10.1590/S0074-02762010000700019
Abstract: the rat lungworm angiostrongylus cantonensis is a worldwide-distributed zoonotic nematode that can cause human eosinophilic meningoencephalitis. here, for the first time, we report the isolation of a. cantonensis from achatina fulica from two brazilian states: rio de janeiro (specifically the municipalities of barra do piraí, situated at the paraiba river valley region and s?o gon?alo, situated at the edge of guanabara bay) and santa catarina (in municipality of joinville). the lungworms were identified by comparing morphological and morphometrical data obtained from adult worms to values obtained from experimental infections of a. cantonensis from pernambuco, brazil, and akita, japan. only a few minor morphological differences that were determined to represent intra-specific variation were observed. this report of a. cantonensis in south and southeast brazil, together with the recent report of the zoonosis and parasite-infected molluscs in northeast brazil, provide evidence of the wide distribution of a. cantonensis in the country. the need for efforts to better understand the role of a. fulica in the transmission of meningoencephalitis in brazil and the surveillance of molluscs and rodents, particularly in ports, is emphasized.
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