oalib

Publish in OALib Journal

ISSN: 2333-9721

APC: Only $99

Submit

Any time

2019 ( 1 )

2018 ( 1 )

2017 ( 1 )

2015 ( 22 )

Custom range...

Search Results: 1 - 10 of 403 matches for " Makris Leonidas "
All listed articles are free for downloading (OA Articles)
Page 1 /403
Display every page Item
The Distribution of the Stress Protein HSP70 in the Cerebellum of Patients with Schizophrenia  [PDF]
Makris Leonidas
Neuroscience & Medicine (NM) , 2012, DOI: 10.4236/nm.2012.34045
Abstract: Data accumulated from neuro-imaging, clinical and morphological studies suggest that the cerebellum is involved in cognitive functions and thus may be important in the etiopathogenesis of schizophrenia, since patients show cognitive abnormalities. In the present study, we have attempted to localize cellular metabolic dysfunctions applying the immunohistochemical and Western blot method to demonstrate the expression of the stress protein HSP70, which is a marker of cellular metabolic dysfunction in the brain. We studied the post mortem brains’ cerebellum of 12 normal controls and 10 schizophrenics. We have used the polyclonal antibody rabbit anti-HSP70 on paraffin sections as well as on nitrocellulose membranes. Bound antibody was detected using the indirect method of streptavidin-peroxidase-DAB. The results in the cerebellum of controls showed intense HSP70 immunoreaction in the synaptic glomeruli of the granular cell layer, in the cytoplasm and dendrites of Purkinje cells. In the same areas of the cerebellum of schizophrenics the HSP70 immunoreactivity was minimal. These results suggest that the reduced levels of HSP70 in the cerebellum are likely to contribute synergistically to the cognitive dysfunction in schizophrenia. This may suggest abnormality of protective neural mechanisms in such pathological conditions.
Genetic Implications in COPD. The Current Knowledge  [PDF]
Ioannis Sotiriou, Demosthenes Makris
Open Journal of Respiratory Diseases (OJRD) , 2013, DOI: 10.4236/ojrd.2013.32009
Abstract: Chronic Obstructive Pulmonary Disease (COPD) is a multifactorial disease in the pathogenesis of which contributes a variety of causative factors including genetic and environmental ones. They may also be interactions of genetic susceptibilities and environmental influences. Towards to that in the pathogenesis of the disease except smoking, it seems to have a great impact the genetic predisposition of the individuals suffering from that serious progressive disease. Regarding to these observations and findings very interesting studies have been conducted in order to elucidate the implications of different genes, and their polymorphisms in disease aetiology. This is a review which elucidates the impact of genetic susceptibility in COPD.
Surfactant Adsorbed at the Oil-Water Interface and Its Elimination  [PDF]
Linfeng Yang, Leonidas Perez Estrada
Journal of Geoscience and Environment Protection (GEP) , 2015, DOI: 10.4236/gep.2015.32007
Abstract:

Surfactants are widely used in the petroleum industry as one kind of Enhanced Oil Recovery methods (EOR). The oil sands mines in Northern Alberta are the largest one in the world. Due to using sodium hydroxide in bitumen extraction process, there are a lot of surfactant molecules in the tailing water. The surfactants from oil sands industry have brought a potential threat to the environment and human health. Depending on the performance of surfactant at the interface, this work focuses on removing these harmful surfactants from the tailing water and not bringing other possible hazardous substances. Moreover, a mathematical model is built to calculate the removal efficiency of the surfactant. The time required for removing the surfactant is determined experimentally. In conclusion, most of surfactant molecules are adsorbed at the oil/water interface. The fraction of the surfactant staying at the oil/water interface is high. Most of the surfactants in tailing water can be eliminated. The time of surfactant migration can be used for setting up the update time of the oil film in the automatic instrument, which can be designed in the future.

COPD exacerbation: Lost in translation
Demosthenes Makris, Demosthenes Bouros
BMC Pulmonary Medicine , 2009, DOI: 10.1186/1471-2466-9-6
Abstract: Chronic Obstructive Pulmonary Disease (COPD) is characterized by exacerbations which are caused mainly by infections of the tracheobronchial tree or by inhalation of toxic gases [1]. During an exacerbation airway inflammation augments and a sustained worsening of patient's condition from the stable state and beyond normal day-to-day variations is observed. COPD exacerbations are a major cause of hospital admissions and frequent exacerbations are associated with increased mortality and impaired health-related quality of life [2]. Previous studies reported also that patients who experience frequently exacerbations may present an accelerating rate of lung function decline [3,4]. In this respect, the management of exacerbations by prompt diagnosis and effective treatment that reduces exacerbation frequency [5,6], should be a major goal in COPD.However, despite the considerable progress in the understanding of the pathobiology of exacerbations and in the evaluation of their consequences, yet, there is no standardised definition of an exacerbation. The landmark study of Fletcher and Peto[7] published in seventies used the definition of "bronchial infections" (chest cold or illnesses during which phlegm production had increased). Later, the Lung Health Study[8] used the definition of "physician visits for lower respiratory illness", while in recent studies such as in the East London Study[3] and in a study performed in Greece[4], the definition of an exacerbation was based on criteria described previously by Anthonisen [9]. These criteria require either, increase of at least two major respiratory symptoms (dyspnea, sputum amount, and sputum purulence) or, increase of one major symptom in addition to at least one minor symptom (wheeze, cough, fever, nasal discharge, sore throat), for at least two consecutive days. Thus, in those previous studies, definitions were based either on patient reported symptom changes [3,4] or, on "healthcare utilisation" due to the worsening of p
Portal vein thrombosis in a patient with HCV cirrhosis and combined hemophilia A and thrombophilia V Leiden
Nikos Eleftheriadis, Pantelis Makris
Therapeutics and Clinical Risk Management , 2010, DOI: http://dx.doi.org/10.2147/TCRM.S13660
Abstract: rtal vein thrombosis in a patient with HCV cirrhosis and combined hemophilia A and thrombophilia V Leiden Rapid Communication (2900) Total Article Views Authors: Nikos Eleftheriadis, Pantelis Makris Published Date October 2010 Volume 2010:6 Pages 539 - 541 DOI: http://dx.doi.org/10.2147/TCRM.S13660 Nikos Eleftheriadis, Pantelis Makris Hemostatic Unit of The First Propedeutic Department of Internal Medicine, AHEPA Hospital, Aristotles University of Thessaloniki, Greece Abstract: The relation of hemophilia A with thrombophilia V Leiden is extremely rare in the literature. Furthermore, hemophiliac patients have an increased risk of severe life-threatening hemorrhage, blood transfusions, and therefore hepatitis transmission, mainly hepatitis C (HCV). Aims and methods: We present a 54-year-old male with a 5-year history of decompensated liver cirrhosis on the grounds of HCV hepatitis, hemophilia A, and thrombophilia V Leiden. He was admitted to our department because of severe abdominal distension, resembling ‘tense ascites’ despite the use of diuretics. Clinical examination showed shifting dullness and a protuberant abdomen, while hematological and blood chemistry results revealed thrombopenia (platelets: 77000/mL) and hypoalbuminemia. Repeated abdominal paracentesis (under factor VIII administration) failed to remove ascitic fluid, while abdominal echosonography and computed tomography revealed severe edema of mesenterium and intraabdominal viscus and the absence of free ascitic fluid, atrophic cirrhotic liver, and splenomegaly. Moreover, abdominal doppler echosonography revealed signs of portal hypertension, previous portal vein thrombosis, and revascularization of the portal vein. Gastroscopy showed esophageal varices grade II, without signs of bleeding. A-FP and all other laboratory examinations were normal. Results: Our patient was intravenously treated with albumine and diuretics (furosemide) with mild improvement of his abdominal distension. During his hospitalization he presented an episode of spontaneous bacterial peritonitis and hepatic encephalopathy, which were successfully treated with lactulose clysmas and ciprofloxacine. He was discharged in a good general condition. Conclusion: According to our case we consider the false clinical picture of ‘tense ascites’ of our patient as a rare clinical presentation of decompensated liver cirrhosis, with severe edema of mesenterium and viscus, on the grounds of preexisting portal vein thrombosis, in a patient with combined hemophilia A and thrombophilia V Leiden.
Optimisation of Anthocyanin Recovery from Onion (Allium cepa) Solid Wastes Using Response Surface Methodology
Dimitris P. Makris
Journal of Food Technology , 2013, DOI: 10.3923/jftech.2010.183.186
Abstract: An experimental setup based on a 23 full factorial,central composite design was implemented with the aim to optimising recovery of anthocyanin recovery from onion solid wastes. In order to allow for the establishment of a sustainable process, reusable and non-toxic solutions composed of water/ethanol/citric acid were employed as extracting media. The factors considered were the pH of the medium, the extraction time and the ethanol concentration. The 2nd order polynomial equation obtained after elaboration of the experimental data indicated that extraction time mostly affected the extraction yield.
Portal vein thrombosis in a patient with HCV cirrhosis and combined hemophilia A and thrombophilia V Leiden
Nikos Eleftheriadis,Pantelis Makris
Therapeutics and Clinical Risk Management , 2010,
Abstract: Nikos Eleftheriadis, Pantelis MakrisHemostatic Unit of The First Propedeutic Department of Internal Medicine, AHEPA Hospital, Aristotles University of Thessaloniki, GreeceAbstract: The relation of hemophilia A with thrombophilia V Leiden is extremely rare in the literature. Furthermore, hemophiliac patients have an increased risk of severe life-threatening hemorrhage, blood transfusions, and therefore hepatitis transmission, mainly hepatitis C (HCV).Aims and methods: We present a 54-year-old male with a 5-year history of decompensated liver cirrhosis on the grounds of HCV hepatitis, hemophilia A, and thrombophilia V Leiden. He was admitted to our department because of severe abdominal distension, resembling ‘tense ascites’ despite the use of diuretics. Clinical examination showed shifting dullness and a protuberant abdomen, while hematological and blood chemistry results revealed thrombopenia (platelets: 77000/mL) and hypoalbuminemia. Repeated abdominal paracentesis (under factor VIII administration) failed to remove ascitic fluid, while abdominal echosonography and computed tomography revealed severe edema of mesenterium and intraabdominal viscus and the absence of free ascitic fluid, atrophic cirrhotic liver, and splenomegaly. Moreover, abdominal doppler echosonography revealed signs of portal hypertension, previous portal vein thrombosis, and revascularization of the portal vein. Gastroscopy showed esophageal varices grade II, without signs of bleeding. A-FP and all other laboratory examinations were normal.Results: Our patient was intravenously treated with albumine and diuretics (furosemide) with mild improvement of his abdominal distension. During his hospitalization he presented an episode of spontaneous bacterial peritonitis and hepatic encephalopathy, which were successfully treated with lactulose clysmas and ciprofloxacine. He was discharged in a good general condition.Conclusion: According to our case we consider the false clinical picture of ‘tense ascites’ of our patient as a rare clinical presentation of decompensated liver cirrhosis, with severe edema of mesenterium and viscus, on the grounds of preexisting portal vein thrombosis, in a patient with combined hemophilia A and thrombophilia V Leiden.Keywords: portal vein thrombosis, HCV cirrhosis, hemophilia A, thrombophilia V Leiden
Properties of the geoelectric structure that promote the detectionof electrotelluric anomalies: the case of Ioannina, Greece
J. P. Makris
Annals of Geophysics , 2001, DOI: 10.4401/ag-3598
Abstract: The reliable detection and identification of electrotelluric anomalies that could be considered as precursory phenomena of earthquakes become fundamental aspects of earthquake prediction research. Special arrangements, in local and/or regional scale, of the geoelectric structure beneath the measuring point, may act as natural real-time "filters" on the ULF electrotelluric data improving considerably the signal to "magnetotelluric-noise" ratio of anomalies originated by probably non-magnetotelluric sources. Linear polarization, i.e. local channelling of the electric field on the surface is expected in cases where 3D-local inhomogeneities, producing strong shear distortion, are present in the vicinity of the monitoring site and/or when a 2D-regional geoelectrical setting exhibits high anisotropy. By assuming different generation mechanisms and modes of propagation for the electrotelluric anomalies that could be considered earthquake precursory phenomena, a rotationally originated residual electrotelluric field results, eliminating background magnetotelluric-noise and revealing "hidden" transient variations that could be associated to earthquakes. The suggested method is applicable in real-time data collection, thus simplifies and accelerates the tedious task of identification of suspicious signals. As an indicative example, the case of Ioannina (located in Northwestern Greece) is presented. The local polarization of the electrotelluric field varies dramatically even at neighboring points although the regional geoelectric strike direction does not change.+
Diamela Eltit: El ensayo como estrategia narrativa
Morales,Leonidas;
Atenea (Concepción) , 2004, DOI: 10.4067/S0718-04622004049000008
Abstract: the central hypothesis of this critical text is that eltit?s novels are permeated by a strategy: that of the essay, as understood in the etymological sense of the word, as an "attempt" or "experiment". nothing is definitive in these novels, neither the subject nor the discourse: the subject is always a figure in movement, in transit and the discourse constructs and reconstructs itself right before the reader?s eyes. without a doubt this is a "post-vanguard" strategy or, also, "post-modern", whose meaning the critical text tries to situate in the context of the contemporary chilean novel. even when the experimental strategy runs through all of eltit?s narrative order, the quotes privilege the novel por la patria.
Money and War Murray Rothbard’s A History of Money and Banking in the United States
Leonidas Zelmanovitz
Libertarian Papers , 2010,
Abstract: This paper is a presentation and an interpretation of Murray Rothbard’s views on the relation between the fiscal necessities brought by war and interventionism in Money and Banking as read from his book A History of Money and Banking in the United States.
Page 1 /403
Display every page Item


Home
Copyright © 2008-2017 Open Access Library. All rights reserved.