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Search Results: 1 - 10 of 142 matches for " Maik Ellies "
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Diseases of the salivary glands in infants and adolescents
Maik Ellies, Rainer Laskawi
Head & Face Medicine , 2010, DOI: 10.1186/1746-160x-6-1
Abstract: Salivary gland diseases are rare in childhood and adolescence. Their pattern of incidence differs very much from that of adults. Acute and chronic sialadenitis not responding to conservative treatment requires an appropriate surgical approach. The rareness of salivary gland tumors is particularly true for the malignant parotid tumors which are more frequent in juvenile patients, a fact that has to be considered in diagnosis and therapy.Diseases of the salivary glands are rare in infants and children (with the exception of diseases such as parotitis epidemica and cytomegaly) and the therapeutic regimen differs from that in adults. It is therefore all the more important to gain exact and extensive insight into general and special aspects of pathological changes of the salivary glands in these age groups. Previous studies [1-3] have dealt with the clinical distribution pattern of the various pathological entities in infants and older children.According to these studies, important pathologies in these age groups are acute and chronic sialadenitis (with special regard to chronic recurrent parotitis) and secondary inflammation associated with sialolithiasis [2,4-6]. The etiology and pathogenesis of these entities in young patients, however, are still not yet sufficiently understood, so that therapeutic strategies based on extensive clinical experience cannot be defined, particularly in view of the small number of patients in the relevant age groups. The acute forms of sialadenitis are mainly caused by viral or bacterial infections. The predominant cause of parotid swelling in infancy is parotitis epidemica [7]. This disease has its peak incidence between the ages of 2 and 14 [8]. Acute inflammation of the parotid gland, with evidence of Staphylococcus aureus, is often seen in neonates and in children with an underlying systemic disease accompanied by fever, dehydration, immunosuppression and general morbidity [4,9]. Acute inflammation of the submandibular gland, as oppose
Improvement of chronic facial pain and facial dyskinesia with the help of botulinum toxin application
Katharina Junghans, Saskia Rohrbach, Maik Ellies, Rainer Laskawi
Head & Face Medicine , 2007, DOI: 10.1186/1746-160x-3-32
Abstract: In this patient, persistent intense pain arose in the lower part of her face following a dental operation. The patient also exhibited dyskinesia of her caudal mimic musculature that was triggered by specific movements. Several attempts at therapy had been unsuccessful. We performed local injections of botulinum toxin type A (BTX-A) into the affected region of the patient's face. Pain relief was immediate following each set of botulinum toxin injections. The follow up time amounts 62 weeks.Botulinum toxin type A (BTX-A) can be a safe and effective therapy for certain forms of facial pain syndromes.The underlying mechanism of a chronic pain syndrome caused by alterations in the area of the trigeminal nerve seems to be an increased activity in trigeminal nerve fibers and an altered inhibition in the trigeminal nucleus. The increased neuronal activity (idiopathic or symptomatic) involves nociceptive neurons resulting in the perception of pain [1-3].Various possible etiologies of chronic facial pain syndromes are known, including 1) disorders of the cranium, neck, eyes, ears, nose, sinuses, teeth, mouth and other facial structures and 2) cranial neuralgias, nerve trunk pain and deafferentiation pain [3]. Facial pain is often caused by cervical and other forms of dystonia, blepharospasm, hemifacial spasm, Meige-syndrome, masticatory hyperactivity, temporomandibular disorders (TMD), bruxism, trigeminal and other cranial neuralgias, tension-type headache or migraine.Chronic facial pain can be difficult to manage [1]. One cause of the pain syndromes may be an affliction of the oral region in the form of lesions of peripheral trigeminal nerve fibers. Atypical facial pain is known to be initiated by surgical trauma in the oral region [4,5] and can also be induced by altered muscle function with hypertonicity [6].There are numerous descriptions in the literature of patients with chronic facial pain or pain-associated dystonias effectively treated by injecting botulinum toxin in
Hybrid Decision Models in Non-Proportional Reinsurance  [PDF]
Maik Wagner
Technology and Investment (TI) , 2010, DOI: 10.4236/ti.2010.11008
Abstract: Over the past years, risk measurement and therewith risk measures became more and more important in economics. While in the past risk measures were already adopted at the deposit of credit and shareholders equity, the approach now generates two hybrid decision models and applies them to the reinsurance business. The two introduced models implement a convex combination of risk measures and with it provide the possibility of modelling risk attitudes. By doing that, for the two hybrid decision models on the one hand can be shown, which risk attitude leads to the acceptance of a reinsurance contract and on the other hand, a deductible of which height an insurer is willing to undertake. Hence the possibility exists to identify the risk attitude of an insurer. In return, due to the knowledge of risk attitudes, under similar conditions the possibility arises to establish recommendations about the extent of the deductible at reinsurance contracts.
Particle asymmetries in the early universe
Maik Stuke
Physics , 2010, DOI: 10.1016/j.ppnp.2011.01.010
Abstract: The total lepton asymmetry $l=\sum_f l_f$ in our universe is only poorly constrained by theories and experiments. It might be orders of magnitudes larger than the observed baryon asymmetry $b\simeq {\cal O}(10^{-10})$, $|l|/b \leq {\cal O}(10^{9})$. We found that the dynamics of the cosmic QCD transition changes for large asymmetries. Predictions for asymmetries in a single flavour $l_f$ allow even larger values. We find that asymmetries of $l_f\leq {\cal O}(1)$ in a single or two flavours change the relic abundance of WIMPs. However, large lepton and large individual lepton flavour asymmetries influences significantly the dynamics of the early universe.
The Madelung Picture as a Foundation of Geometric Quantum Theory
Maik Reddiger
Physics , 2015,
Abstract: Despite its age quantum theory remains ill-understood, which is partially to blame on its deep interwovenness with the mysterious concept of quantization. In this article we argue that a quantum theory recoursing to quantization algorithms is necessarily incomplete. To provide a new axiomatic foundation, we give a rigorous proof showing how the Schr\"odinger equation follows from the Madelung equations, which are formulated in the language of Newtonian mechanics. We show how the Schr\"odinger picture relates to this Madelung picture and how the "classical limit" is directly obtained. This suggests a reformulation of the correspondence principle, stating that a quantum theory must reduce to a probabilistic version of Newtonian mechanics for large masses. We then enhance the stochastic interpretation developed by Tsekov, which speculates that quantum mechanical behavior is caused by random vibrations in spacetime. A new, yet incomplete model of particle creation and annihilation is also proposed.
Conditioning of Gaussian processes and a zero area Brownian bridge
Maik Gorgens
Mathematics , 2013,
Abstract: We generalize the notion of Gaussian bridges by conditioning Gaussian processes given that certain linear functionals of the sample paths vanish. We show the equivalence of the laws of the unconditioned and the conditioned process and by an application of Girsanov's theorem, we show that the conditioned process follows a stochastic differential equation (SDE) whenever the unconditioned process does. In the Markovian case, we are able to determine the coefficients in the SDE of the conditioned process explicitly. Our main example is Brownian motion on $[0,1]$ pinned down in 0 at time 1 and conditioned to have vanishing area spanned by the sample paths.
Effect of management of a volcanic ash soil on structural properties
Ellies A.,Horn R.,Smith R.
International Agrophysics , 2000,
Abstract: In Hapludand, Southern Chile with different types of land use and differentiated time periods after clear-cutting of the native forest by fire, the following parameters: pore size distribution, bearing capacity, internal cohesion, penetration resistance and spatial stress distri- bution due to loading were determined. The most pro- nounced settlement occurs immediately after forest clear- ing. During consecutive periods of land use, the settlement rate became smaller. Additionally, the major settlements occur on the sites with a long time of agricultural landuse while mere strong grassing had a smaller effect. As ex- pected, changes in the pore size distribution could be de- tected. Coarse pores decrease and the amount of medium pores increases. These changes depended on the pedolo- gical environment and soil use. Due to the rearrangement of the parent volcanic ash material and the corresponding aggregates during soil settlement as a consequence of stress induced changes in the shape of the particles and the more spherical shape, soil penetration resistance increased with settlement as well as the amount of roots above the plow pan layer. The latter is also an index of the impermeability as a consequence of the assumed increase in the contact points due to loading and ¢ € reformation ¢ € of these particles. Accor- ding to utilization-type, soil strength differs. The same soil can either react very stable or is extremely weak even if only a small stress, e.g., by an agricultural machinery, has been applied. Recently, cultivated agricultural sites have low pre- compression strength and internal cohesion values. Due to the rearrangement of particles and shape as a consequence of soil deformation during land use the strength increase even if the pore size distribution doesn ¢ € t change con- siderably. More detailed informations are given in the text.
Metabolic Properties of Fibers and Connective Tissue of Four Muscles from Bovine Carcasses  [PDF]
Marie-Pierre Ellies-Oury, Rollande Dumont, Didier Micol, Yves Durand, Brigitte Picard
Food and Nutrition Sciences (FNS) , 2015, DOI: 10.4236/fns.2015.616157
Abstract: Meat-grain-size (MGS) assessment is an empirical method for the early prediction of meat quality, a larger grain being synonymous with higher meat tenderness. The objective was to characterize 4 muscles (longissimus thoracis LT; rectus abdominis RA; longus colli LC; diaphragma D) of 5 coarse and 5 fine carcasses in terms of MGS in order to establish a link between muscular physicochemical properties and carcass MGS score. All comparisons were made of samples with similar fat content. The broiled sample hardness (shear force) was significantly higher for the coarse group than for the fine group (7.20 vs 5.89 kg; RA). Higher collagen content (27.94 vs 24.87 mg/g of dry matter in LT muscle; 15.86 vs 13.13 mg/g of dry matter in D muscle), higher oxidative metabolism (cytochrome-c oxidase; LT and D) but also higher glycolytic metabolism (lactate dehydrogenase; LT) were also observed in the coarse groups. Not all the muscles react in a similar way depending on the MGS group. Nevertheless, significant results are constant from one muscle to another, the RA being the only muscle for which the difference in hardness between the two groups is significant.
Role of Ryanodine Receptor Subtypes in Initiation and Formation of Calcium Sparks in Arterial Smooth Muscle: Comparison with Striated Muscle
Kirill Essin,Maik Gollasch
Journal of Biomedicine and Biotechnology , 2009, DOI: 10.1155/2009/135249
Abstract: Calcium sparks represent local, rapid, and transient calcium release events from a cluster of ryanodine receptors (RyRs) in the sarcoplasmic reticulum. In arterial smooth muscle cells (SMCs), calcium sparks activate calcium-dependent potassium channels causing decrease in the global intracellular [Ca2
Identification of superior reference genes for data normalisation of expression studies via quantitative PCR in hybrid roses (Rosa hybrida)
Maik Klie, Thomas Debener
BMC Research Notes , 2011, DOI: 10.1186/1756-0500-4-518
Abstract: We used three different algorithms (BestKeeper, geNorm and NormFinder) to validate the expression stability of nine candidate reference genes in different rose tissues from three different genotypes of Rosa hybrida and in leaves treated with various stress factors. The candidate genes comprised the classical "housekeeping genes" (Actin, EF-1α, GAPDH, Tubulin and Ubiquitin), and genes showing stable expression in studies in Arabidopsis (PP2A, SAND, TIP and UBC). The programs identified no single gene that showed stable expression under all of the conditions tested, and the individual rankings of the genes differed between the algorithms. Nevertheless the new candidate genes, specifically, PP2A and UBC, were ranked higher as compared to the other traditional reference genes. In general, Tubulin showed the most variable expression and should be avoided as a reference gene.Reference genes evaluated as suitable in experiments with Arabidopsis thaliana were stably expressed in roses under various experimental conditions. In most cases, these genes outperformed conventional reference genes, such as EF1-α and Tubulin. We identified PP2A, SAND and UBC as suitable reference genes, which in different combinations may be used for normalisation in expression analyses via qPCR for different rose tissues and stress treatments. However, the vast genetic variation found within the genus Rosa, including differences in ploidy levels, might also influence expression stability of reference genes, so that future research should also consider different genotypes and ploidy levels.Roses are one of the economically most important ornamentals worldwide. They are produced as cut and potted plants and garden and landscaping plants with a production value of 24 billion Euros from 1995 to 2007 [1]. Other, less prominent uses include medicinal applications or the consumption in teas and soups [2]. Apart from the beauty of their flowers, roses are also admired for their delicate scent. Their scent
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