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Search Results: 1 - 10 of 138866 matches for " Mahinder K. Chhabra "
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Prevalence and clinical characteristics of headache in dental students of a tertiary care teaching dental hospital in Northern India
Ruchika Nandha,Mahinder K. Chhabra
International Journal of Basic & Clinical Pharmacology , 2013, DOI: 10.5455/2319-2003.ijbcp20130110
Abstract: Background: Chronic headache is as much as a problem in India as elsewhere in the world with a rising trend in young adults which negatively affects the quality of life of the affected person. In current scenario of increasing prevalence of headache in students, most of them have been found to practice self medication leading to inappropriate management and sometimes analgesic overuse causing treatment refractoriness. Methods: A questionnaire based survey was done on undergraduate dental students at a tertiary care dental teaching hospital in Northern India. Severity of headache was assessed by Numeric Rating Scale. Data collected was analyzed to assess the prevalence, pattern & triggering factors of headache along with awareness of dental students regarding treatment. Prevalence and characteristics of migraine were also assessed along with the therapeutic strategies opted by students. Results: Our study (n=186) demonstrated headache prevalence of 63.9% which was higher in females (74.3%) as compared to males (32.6%). Headache experienced by majority of student population was bilateral (36.13%), sharp stabbing (38.65%) and of moderate intensity (57.98%). Common associated symptoms were nausea/ vomiting (24.36%) and scalp tenderness (22.68%). Stress (82.3%) &irregular sleep (81.5%) were the most common triggering factors. Prevalence of migraine was 13.44% with female preponderance (87.5%). Practice of self medication was reported by 88.2% of students. Most commonly used drugs were paracetamol (36.76%), aspirin (26.47%) and combination of ibuprofen and paracetamol (25%). Specific medication use in migraineurs was found to be low (25%) showing inadequate management of migraine headache in our study population. Conclusions: The results in this study demonstrate high headache prevalence in dental students with self medication being practiced by the majority. [Int J Basic Clin Pharmacol 2013; 2(1.000): 51-55]
The fertility rate in Canada, 1950-1976: a socio-econometric analysis
Chaudhry, Mahinder D.,Choudhry, Nanda K.
Canadian Studies in Population , 1985,
Effect of Smoking on Body Mass Index: A Community-Based Study
Pragti Chhabra, Sunil K Chhabra
National Journal of Community Medicine , 2011,
Abstract: Smoking has a negative effect on Body Mass Index (BMI). This association may be confounded by demographic factors. Secondary analysis of data of 3446 non-smokers and 948 current smokers from a previously published community study on respiratory morbidity in Delhi was carried out to examine the association between smoking and BMI, and the confounding effects of gender and economic status. The BMI values were higher among non- smokers while smokers had a higher proportion of underweights. After adjusting for gender and economic status, the odds ratio for being underweight was 1.34 (95% CI 1.13-1.6) among smokers whereas non-smokers had an adjusted odds ratio for overweight/obesity of 2.16 (95% CI 1.24-3.78). The study shows that smoking is independently associated with reduced BMI after adjusting for gender and economic status in an Indian population.
Nutritional Status and Blood Pressure of Medical Students in Delhi
Chhabra P,Grover V,Aggarwal K,Kannan AT
Indian Journal of Community Medicine , 2006,
Study on Pathogenicity of the Aspergillus species in experimentally immunosuppressed mice
Chhabra,D. and Dhakad,N.K.
Veterinary World , 2008,
Abstract: Aspergillus, a saprophytic mould, distributed widely in the environment is a frequently recognized etiological agent in a number of disease conditions especially in immunocompromised patients. Mice untreated as well as immunocompromised by administering cortisone, were inoculated intraperitoneally with spores of Aspergillus spp. The administration of cortisone rendered mice highly susceptible to fatal visceral aspergillosis. Heat killed spores produced no evident lesions in control or experimental mice. [Veterinary World 2008; 1(3.000): 69-70]
Unusual course of the median nerve
Vashishtha K,Kaushal S,Chhabra U
International Journal of Anatomical Variations , 2010,
Abstract: One extremely unusual observation has been reported in this case report. During dissection of left hand of an adult human cadaver we found median nerve passing through the substance of flexor retinaculum. Median nerve coursed through the entire extent of flexor retinaculum in a fascial canal. No other structure was found along with nerve in the fascial canal. After emerging from the flexor retinaculum median nerve took its usual course in the hand. To the best of our knowledge this kind of variant median nerve course has not been described in published literature.
Split cord malformation (scm) in paediatric patients : outcome of 19 cases.
Kumar R,Bansal K,Chhabra D
Neurology India , 2001,
Abstract: There had been considerable debate regarding the surgical outcome of neuro-orthopaedic syndromes (NOS) and neurological syndromes in cases of split cord malformation (SCM). On retrospective analysis of 19 cases of SCM, thirteen were grouped under (Pang) type I and 6 in type II. Their age ranged from 1 month to 9 years (mean 3.5 years). 14 of these were male children. The NOS without neurological signs was detected in 6 cases where as pure neurological signs without NOS were seen in 8 patients. However, the rest 5 had mixed picture of NOS and neurological dysfunction. Nine of 19 cases presented with cutaneous stigmata, mainly in the form of hairy patch. 18 cases had other associated craniospinal anomalies i.e. hydrocephalus, meningomyelocoele, syrinx, dermoid, teratoma etc. Detethering of cord was done in all cases by removal of fibrous/bony septum. Associated anomalies were also treated accordingly. Follow up of these cases ranged from 6 months to 6 years. Six cases of NOS group neither showed deterioration nor improvement, and remained static on follow up. However, four of 8 children with neurological signs showed improvement in their motor weakness, and 1 in saddle hypoaesthesia as well as bladder/bowel function. In 5 cases of mixed group, two had improvement in their weakness and one in hypoaesthesia, but no change was noticed in NOS of this group as well. Hence surgery seemed to be effective, particularly in patients with neurological dysfunction.
Association of lower cranial nerve schwannoma with spinal ependymoma in ? NF2.
Kumar R,Sharma K,Chhabra D
Neurology India , 1999,
Abstract: A 15 year old male, who had earlier been operated for intraspinal intramedullary ependymoma, subsequently developed a right cerebello pontine (CP) angle mass. A diagnosis of right CP angle ependymoma was considered, in view of established histology of previously operated spinal lesion. Histopathological examination of the well defined extra-axial mass, which was attached with ninth cranial nerve, however revealed a schwannoma. A diagnosis of Neurofibromatosis-2 (NF2) is strongly suspected, because of well established fact, that the spinal ependymomas may have association with lower cranial nerve schwannomas in NF2. Cranial and spinal MRI screening for early diagnosis of associated, asymptomatic lesions, in suspected cases of NF2, particularly in children, is recommended.
Critical Role of Protein Kinase C (PKC) in the Onset of Airway Hypersensitivity in Ova-Sensitized Guinea Pig Model of Asthma  [PDF]
Rakesh Kumar Mishra, Ritu Kulshrestha, Sunil Kumar Chhabra, Satish K. Srivastav, Surendra Kumar Bansal
Open Journal of Respiratory Diseases (OJRD) , 2014, DOI: 10.4236/ojrd.2014.41001
Background and Objectives: Protein kinase C (PKC) activation plays an important role in activation of T-lymphocytes in asthma. Airway hypersensitivity is one of the main characteristic features of asthma, the mechanism of onset of which is not clearly understood. Therefore, the objective was to elucidate the role of PKC in etiopathogenesis of airway hypersensitivity in asthma. Methods: Male guinea pigs (n = 30) were sensitized with ovalbumin and day of initial allergen-specific immune response determined by intradermal test, airway hypersensitivity, BALF cytology and lung histopathology. Total PKC activity, PKC isoenzymes and phosphoinositides were assessed in airway smooth muscles (ASM) and peripheral blood lymphocytes. Results: Intradermal test revealed that day 9 was the earliest time of allergen-specific response and onset of airway hypersensitivity to ovalbumin. It was associated with significant increase in total and differential (lymphocytes and eosinophils) BALF counts and grade I peribronchiolar chronic lymphocytic inflammation in lung. On day 14, grade II infiltration of lymphocytes and eosinophils with onset ofstructural remodelingofproximal and distal airways was seen. Total PKC activity, expression of PKCα, PKCε and phosphoinositides increased significantly in ASM and lymphocytes on day 9 and were maximum on day 14. There was no change in PKC-τ expression. Conclusions: Activation of PKC, particularly PKCα and PKCε, mediated signal transduction pathway plays a critical role in lymphocyte infiltration and onset of airway hypersensitivity, airway remodeling and asthma pathophysiology. The present study is the first one on the mechanism of the etiopathogenesis of the disease, which shows a direct evidence of the role of PKC mediated pathway in the initiation and onset of airway
A New Fourth Order Difference Approximation for the Solution of Three-dimensional Non-linear Biharmonic Equations Using Coupled Approach  [PDF]
Ranjan Kumar Mohanty, Mahinder Kumar Jain, Biranchi Narayan Mishra
American Journal of Computational Mathematics (AJCM) , 2011, DOI: 10.4236/ajcm.2011.14038
Abstract: This paper deals with a new higher order compact difference scheme, which is, O(h4) using coupled approach on the 19-point 3D stencil for the solution of three dimensional nonlinear biharmonic equations. At each internal grid point, the solution u(x,y,z) and its Laplacian Δ4u are obtained. The resulting stencil algo-rithm is presented and hence this new algorithm can be easily incorporated to solve many problems. The present discretization allows us to use the Dirichlet boundary conditions only and there is no need to discretize the derivative boundary conditions near the boundary. We also show that special treatment is required to handle the boundary conditions. Convergence analysis for a model problem is briefly discussed. The method is tested on three problems and compares very favourably with the corresponding second order approximation which we also discuss using coupled approach.
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