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Structured exercise interventions for type 2 diabetes mellitus: Strength of current evidence
Unaise Abdul Hameed,MY Shereef,Mohammed Ejas Hussain
Journal of Medical and Allied Sciences , 2011,
Abstract: Exercise, along with medical nutrition therapy and pharmacological interventions, is an important component in the clinical management of type 2 diabetes mellitus (T2D). Current clinical guidelines on type 2 diabetes provide no detailed information on the modalities of effective exercise intervention in the treatment of type 2 diabetes. Both endurance and resistance types of exercise seem to be equally effective in improving metabolic control in patients with type 2 diabetes. Determining the best method of providing exercise is clinically relevant to this population. This paper reviews the epidemiology of diabetes and problems of physical function associated with type 2 diabetes and discuss the benefits of exercise therapy on the parameters of glycemic control and function in type 2 diabetes patients, with special reference to Asian Indians. Based on the currently available literature, it is concluded that type 2 diabetes patients should be encouraged to participate in specifically designed exercise intervention programs. Attention should be paid to the avoidance of cardiovascular and musculoskeletal deconditioning. More clinical research is warranted to establish the efficacy of different dosages of exercise intervention in a holistic approach for type 2 diabetes subpopulations within different stages of the disease and various levels of co-morbidity.
Hereditary spherocytosis presenting as indolent leg ulcers
Muhammed K,Lilly S,Shereef P
Indian Journal of Dermatology, Venereology and Leprology , 1997,
Abstract: Indolent leg ulcertation, which is the rarest manifestation of hereditary spherocytosis, started at the age of 5 years affecting a 15-year-old boy and his mother is reported. Review of literature showed very few reports from India and abroad. The response to oral folic acid was excellent
A New Weather Forecasting Technique using Back Propagation Neural Network with Modified Levenberg-Marquardt Algorithm for Learning
I.Kadar Shereef,S. Santhosh Baboo
International Journal of Computer Science Issues , 2011,
Abstract: Temperature warnings are essential forecasts since they are utilized to guard life and property. Temperature forecasting is the kind of science and technology to approximate the temperature for a future time and for a given place. Temperature forecasts are performed by means of gathering quantitative data regarding the in progress state of the atmosphere. The author in this paper utilized a neural network-based technique for determining the temperature in future. The Neural Networks package consists of various kinds of training or learning techniques. One such technique is Back Propagation Neural Network (BPN) technique. The main advantage of the Back Propagation Neural Network technique is that it can reasonably estimated a large class of functions. This technique is more efficient than numerical differentiation. The simple meaning of this term is that the proposed technique has ability to confine the complex relationships among several factors that contribute to assured temperature. The proposed idea is tested using the real time dataset. In order to further improve the prediction accuracy, this paper uses Modified Levenberg-Marquardt (LM) Algorithm for Neural Network learning. In modified LM, the learning parameters are modified. The proposed algorithm has good convergence and also it reduces the amount of oscillation in learning procedure. The proposed technique is compare with the usage of BPN and the practical working of meteorological department. The experimental result shows that the proposed technique results in better accuracy of prediction when compared to the conventional technique of weather prediction.
Design and Implementation of Mobile ServicesEvaluation System  [PDF]
Ruyi My, Jian Liu
Communications and Network (CN) , 2013, DOI: 10.4236/cn.2013.53B2064
Abstract: With the development of mobile network technology, mobile Web services have also been more and more attention, but standard Web protocols are not applicable in a mobile environment, so people began to design more efficient, compact and consume less mobile Web services protocol. In the course of research services protocol, a convenient and practical evaluation system will undoubtedly bring great help for the protocol, the paper design of mobile service evaluation system using a graphical way to display a variety of mobile services in the overhead data, system design a lightweight service protocol, and the protocol by the system for evaluation compared with a standard Web.
RAG: An update to the RNA-As-Graphs resource
Joseph A Izzo, Namhee Kim, Shereef Elmetwaly, Tamar Schlick
BMC Bioinformatics , 2011, DOI: 10.1186/1471-2105-12-219
Abstract: Our RAG update includes a new supervised clustering algorithm that can suggest RNA motifs that may be "RNA-like". We use this utility to describe RNA motifs as three classes: existing, RNA-like, and non-RNA-like. This produces 126 tree and 16,658 dual graphs as candidate RNA-like topologies using the supervised clustering algorithm with existing RNAs serving as the training data. A comparison of this clustering approach to an earlier method shows considerable improvements. Additional RAG features include greatly expanded search capabilities, an interface to better utilize the benefits of relational database, and improvements to several of the utilities such as directed/labeled graphs and a subgraph search program.The RAG updates presented here augment the database's intended function - stimulating the search for novel RNA functionality - by classifying available motifs, suggesting new motifs for design, and allowing for more specific searches for specific topologies. The updated RAG web resource offers users a graph-based tool for exploring available RNA motifs and suggesting new RNAs for design.The RAG (RNA-As-Graphs) web resource was launched in 2004 to classify and catalogue all possible RNA 2D topologies, including existing and hypothetical motifs http://www.biomath.nyu.edu/rna webcite[1,2]. RAG's construction was motivated by the increasing importance of RNAs, structurally diverse molecules with significant regulatory roles including protein synthesis, transcriptional regulation and other integral biological functions [3-8]. Many databases have been designed for classifying existing RNAs. These include the NDB (nucleic acid database) [9,10], Rfam (RNA families with consensus secondary structures) [11,12], SCOR (structural classifications of RNAs) [13,14], RNA Strand (secondary structures) [15], and Pseudobase++ (RNAs containing pseudoknots) databases [16,17].To aid these classification efforts, RAG was designed to enumerate and classify all possible RNA topolog
Synthesis of ZnO based nanopowders via a non-hydrolytic sol gel technique and their densification behaviour and varistor properties
Shereef Anas,Poothayil Mukundan,Ayyappan M. Sanoj,Viswanathan R. Mangalaraja
Processing and Application of Ceramics , 2010,
Abstract: Hexagonal nanocrystalline varistor grade ZnO particles with size 50 nm and the specific surface area of 28 m2/g have been prepared by non-aqueous gelation technique involving diethylene glycol and triethanolamine. The as-prepared varistor nanopowders were analyzed with the support of XRD, TG/DTA, FTIR, TMA, SEM and TEM. Varistor discs were fabricated by pressing and their densification was studied at 850, 950, 1050 and 1150°C. The evolution of varistor microstructures, extent of grain growth and the influence of microstructure on the I-V properties were explored and presented.
Heat and moisture exchanger PALLBB22-15F can prevent ventilator-associated pneumonia (VAP) in short term mechanically ventilated ICU patients
MY Yassin
Critical Care , 2000, DOI: 10.1186/cc390
Abstract: Subjects were intubated and attached to the conventional respiratory assistance cascades in the first year of the study (July 1992-June 1993). Retrospectively, cases of VAP were calculated prospectively, during the following year (July l993-June 1994), subjects were intubated and attached to respiratory assistance cascades; but PALL filter, a heat and moisture exchanger, was in-line and the machine humidifiers were bypassed. The cases of VAP were calculated.Intubated ICU patients with normal CXR on admission to the unit.VAP rates decreased in the group of HMEF dramatically in comparison to the conventional humidification method (see Table below).We concluded that heat and moisture exchanger filters can prevent VAP in short term mechanically ventilated ICU patients, and can halve its rate in long term durations.
Nrf2 transcription factor gene regulates basal transcription of mitochondrial superoxide dismutase enzyme in mouse brain
MY Gwarzo
African Journal of Biotechnology , 2009,
Abstract: Evidence suggests that the Nrf2 transcription factor participates in the regulation of expression of genes that contain functional antioxidant responsive elements (AREs) in their promoter regions. Previous studies have shown that induction of glutathione-S- transferases (GST) and NADPH quinone reductase 1 (NQO1) by t-butylated hydroxy anisole (BHA) is impaired in the livers of Nrf2(-/-) mice. Basal expression of certain antioxidant enzymes is also lower in the livers of Nrf2 (-/-) mice. Results indicate that Nrf2 contributes to basal expression but not inducible expression of mitochondrial superoxide dismutase. SOD2 level was affected in the Nrf2(-/-) and about 2-fold lower than the Nrf2(+/+) mouse control. The dietary additives caused a small induction of SOD2 in the Nrf2(-/-) mouse brain, ethoxyquin and kahwoel palmitate each induced SOD2 marginally, while oltipraz and indole-3-carbinol caused 1.5 fold induction in the Nrf2(-/-) mouse brain. In contrast, there was no obvious effect on SOD2 in the Nrf2(+/+) mouse brain by any of the chemicals used .
An investigation of the relation between the 30 meter running time and the femoral volume fraction in the thigh
MY Tasmektepligil
Biology of Sport , 2009,
Abstract: Leg components are thought to be a related to speed. Only a limited number of studies have, however, examined the interaction between speed and bone size. In this study, we examined the relationship between the time taken by football players to run thirty meters and the fraction which the femur forms compared to the entire thigh region. Data collected from thirty male football players of average age 17.3 (between 16-19 years old) were analyzed. First we detected the thirty meter running times and then we estimated the volume fraction of the femur to the entire thigh region using stereological methods on magnetic resonance images. Our data showed that there was a highly negative relationship between the 30 meter running times and the volume fraction of the bone to the thigh region. Thus, 30 meter running time decreases as the fraction of the bone to the thigh region increases. In other words, speed increases as the fraction of bone volume increases. Our data indicate that selecting sportsman whose femoral volume fractions are high will provide a significant benefit to enhancing performance in those branches of sports which require speed. Moreover, we concluded that training which can increase the bone volume fraction should be practiced when an increase in speed is desired and that the changes in the fraction of thigh region components should be monitored during these trainings.
Optimal Spacing Design for Pilots in OFDM Systems over Multipath Fading Channels  [PDF]
Youssefi My Abdelkader, El Abbadi Jamal
Communications and Network (CN) , 2010, DOI: 10.4236/cn.2010.24032
Abstract: In wireless orthogonal frequency division multiplexing (OFDM) systems, the time-varying channel is often estimated by algorithms based on pilot symbols. Such an estimator, however, requires statistical prior knowledge that is not easily obtained. Therefore, the pilot tones have to be close enough to fulfill the sampling theorem. In this case the statistical knowledge of the channel is not required to reconstruct correctly the channel impulse response (CIR). This paper explores the optimal placement and number of pilot symbols, we investigate optimal training sequences in OFDM systems and we analyze the number of pilot symbols required to fulfill the sampling theorem. Using a general model for a multipath slowly fading channel, the approach is based on the LS as a criterion of channel estimation while the channel interpolation is done using the piecewise-constant interpolation compromising between complexity and performance. Simulation results demonstrate the good performance of our approach.
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