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Search Results: 1 - 10 of 1817 matches for " MR Sigdel "
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Lupus Nephritis: A comprehensive review
MR Sigdel,DS Shab,KB Raut
Journal of Institute of Medicine , 2013, DOI: 10.2126/joim.v35i1.8901
Abstract: DOI: http://dx.doi.org/10.2126/joim.v35i1.8901 ? Journal of Institute of Medicine, April, 2013; 35:58-70
Seasonal Contrast in Precipitation Mechanisms over Nepal Deduced from Relationship with the Large-Scale Climate Patterns
Madan Sigdel,Motoyoshi Ikeda
Nepal Journal of Science and Technology , 2012, DOI: 10.3126/njst.v13i1.7450
Abstract: Summer precipitation dominates over winter one for the annual total in south Asia, while the winter condition is still important for agricultural productions. Rain gauge data over Nepal were analyzed with large-scale atmospheric patterns such as El Ni?o-Southern Oscillation (ENSO) and Indian Ocean Dipole (IOD). In the period of June to September, summer monsoon rainfall over Nepal (SMRN) is generally higher in the eastern region along with a peak in the central region associated with the local orography. Its interannual variability was found to be correlated with the southern oscillation index (SOI): i.e., when La Ni?a occurs, eastward moisture flux is blocked over Bay of Bengal (BOB) by the anomalous Walker circulation extending from the Pacific. The local-scale condition for higher SMRN is implied by a main moisture route along the eastern arm of the low pressure in northeastern India, as proved by a significant correlation between SMRN and the northward moisture flux. In winter (DJFM), precipitation occurs more in the western region. The higher winter precipitation over Nepal (WPN) was correlated almost equally with positive Dipole Mode Index (DMI) over the Indian Ocean and also SOI, while the relationship with SOI is reversed from summer. A clear linkage was suggested with moisture flux from the Arabian Sea and the further western region. Thus, possible impacts of anomalous precipitation have to be predicted under the relationship with the large-scale indices depending on seasons.
Pattern of Ear Diseases among Paediatric ENT Patient: An Experience from Tertiary Care Centre, Pokhara, Nepal
B Sigdel,R Nepali
Journal of Nepal Paediatric Society , 2012, DOI: 10.3126/jnps.v32i2.5673
Abstract: Introduction : Ear diseases are common in children mainly due to altered anatomy of Eustachian tube which is straighter in children as compared to that in adults. However, the cause of hearing loss in children is more varied, including the etiologies. This study was done to find out the pattern of ear diseases in paediatric age group attending ear, nose and throat OPD in a tertiary care centre in Pokhara, Nepal. Materials and Methods: This is a prospective study done in paediatric patients attending ENT OPD over a period of one year from January 2010 to January 2011. The diagnoses were made on the basis of history and clinical examination. Results were expressed in numbers and percentages. Results: Out of 1632 Pediatric ENT patients, 944 had ear diseases, 59.2% were males and 40.8% females. Wax (33.4%) was the commonest diagnosis followed by Chronic suppurative otitis media (24.3%) and Acute ottitis media (13%). Conclusion: Ear diseases are most common condition in ENT OPD among paediatric age group. Wax, CSOM and ASOM were the three most common ear diseases. J. Nepal Paediatr. Soc. 32(2) 2012 142-145 doi: http://dx.doi.org/10.3126/jnps.v32i2.5673
Altitudinally coordinated pattern of plant community structure in the Shivapuri National Park, Nepal
Shalik Ram Sigdel
Banko Janakari , 2008, DOI: 10.3126/banko.v18i1.2161
Abstract: Study on plant community structure was undertaken in different altitudinal ranges of Shivapuri National Park. The general objective of this study is to analyse different plant community structure in Shivapuri National Park with regards to altitudinal variation. The forest was divided into three distinct altitudinal ranges on the basis of dominancy. In each altitudinal range standard quadrats method was applied for vegetation analysis. The highest number of species was found in site II. All the ecological parameters of the plant species were higher in site II except Basal Area of tree that was highest in site III. The pattern of distribution of plant species was not uniform according to altitude. At higher elevation, the forest was mature with almost closed canopy and trees were large; so the tree density was low. Species richness was highest in site II. Species diversity among tree and shrub species was higher in site I. But for herb species diversity was higher in site II for both seasons. Such type of variations may be due to nature of soil i.e. acidity, nutrient availability and other micro-climatic factors. The most noteworthy thing was that variation in flower colour of Rhododendron arboreum i.e. deep scarlet at low altitude, but it gradually changed into pinkish white as altitude increased.
Spatial and Temporal Analysis of Drought in Nepal using Standardized Precipitation Index and its Relationship with Climate Indices
M Sigdel,M Ikeda
Journal of Hydrology and Meteorology , 2010, DOI: 10.3126/jhm.v7i1.5617
Abstract: Drought over Nepal is studied on the basis of precipitation as a key parameter. Using monthly mean precipitation data for a period of 33 years, Standardized Precipitation Index (SPI) is produced for the drought analysis with the time scale of 3 months (SPI-3) and 12 months (SPI-12) as they are applicable for agriculture and hydrological aspects, respectively. Time-space variability is explored based on Principal Component Analysis (PCA) along with Rotated PCA (RPCA). Four rotated components were explored for both SPI-3 and SPI-12 representing climatic variability with cores over eastern, central and western Nepal separately. Droughts associated with SPI-3 occurred almost evenly over these regions. Droughts associated with SPI-12 were consistent with SPI-3 for summer, since summer precipitation dominates annual precipitation. Connection between SPI and the climate indices such as Southern Oscillation Index (SOI) and Indian Ocean Dipole Mode Index (DMI) was studied, suggesting that one of the causes for summer droughts is El Nino, while the winter droughts could be related with positive DMI. Keywords: Standardized Precipitation Index; Nepal; Principal component analysis; Drought DOI: http://dx.doi.org/10.3126/jhm.v7i1.5617 JHM 2010; 7(1): 59-74
Study of endometrial Status of Patients with Abnormal Uterine Bleeding in Patan Hospital
Sabina Shrestha,B Sigdel
Journal of College of Medical Sciences-Nepal , 2013, DOI: 10.3126/jcmsn.v9i2.9683
Abstract: Background:? Abnormal uterine bleeding may be defined as changes in frequency of menstruation, duration of flow or amount of blood loss. Early accurate diagnosis and proper treatment is essential to prevent progress to endometrial cancer. Objective:? This study was done to evaluate the histopathology of endometrium for identifying the endometrial causes of abnormal uterine bleeding. Method:? This was a retrospective study done in department of pathology, Patan Hospital from 1 August 2011- to 31 July 2012; total 413 cases were included in this study. Results:? The age of the patients ranged from 19 to 70 years. The most common clinical presentation was menorrhagia (47.46%), followed by continuous bleeding (14.04%) and metrorrhagia (13%). The commonest histopathological diagnosis was secretory endometrium 128 cases (30.99%), followed by proliferative endometrium 91 cases (22.03 %). Secretory endometrium was most commonly (52 cases) observed in 41-50 years age group followed by 43 cases in 30-40 years age group. Similarly proliferative endometrium was also most commonly seen in 41-50 age group (44 cases) followed by 31-40 years of age group (32cases). Malignant disease was most commonly seen in 51-60 years age group. Conclusions:? Abnormal uterine bleeding is most common in 21-30 years age group.The most common clinical presentation is menorrhagia followed by continuous bleeding. Secretory endometrium is the most common histopathological findings. Malignancy is more common in postmenopausal group. Journal of College of Medical Sciences-Nepal, 2013, Vol-9, No-2, 20-24 DOI: http://dx.doi.org/10.3126/jcmsn.v9i2.9683
Systemic Lupus Erythematosus presenting with Bullous lesion, Lupus Nephritis and Seizure
Mahseh Raj Sigdel
Journal of Advances in Internal Medicine , 2013, DOI: 10.3126/jaim.v2i1.7633
Abstract: Development of bullous lesion is a rare cutaneous manifestation of systemic lupus erythematosus (SLE). Bullous eruptions in SLE are divided into three categories. Firstly, the lesions of SLE may blister. Secondly, a number of primarily blistering diseases have been associated with SLE.Thirdly, bullous SLE (BSLE), characterized bysub-epidermal blisters, IgG deposition at the dermoepidermal junction and autoantibodies against collagen VII, forms a distinct group. We report an18 years girl who met American College of Rheumatology diagnostic criteria for SLE presenting with bullous lesion and nephritis and developed seizure during the same admission. She had anti-nuclear antibody positive, anti-DsDNA antibody negative and serum complement, C3, level decreased. She was managed with steroid, hydroxychloroquine and cyclophosphamide to which her renal function improved significantly and the skin lesions remitted partially. We would also like to highlight the difficulties in establishing differential diagnoses of bullous lesion in SLE. Journal of Advances in Internal Medicine 2013;02(01):17-20 DOI: http://dx.doi.org/10.3126/jaim.v2i1.7633
Urological complications after Kidney transplantation
P R Chalise,U T Sharma,P R Gyawali,G N Shrestha,B R Joshi,G S Gurung,R K Ghimire,M P Kafle,M R Sigdel,D S Shah,K B Raut,Mr. Sidharth
Kathmandu University Medical Journal , 2010, DOI: 10.3126/kumj.v8i3.6216
Abstract: Background Renal transplantation is a regular service at Tribhuvan University Teaching Hospital and complications have been known to occur after it. This study was conducted to assess complications after transplantation. Objectives To determine the incidence of urological complications after living related renal transplantation at Tribhuvan University Teaching Hospital. Methods A clinical study was performed (from August 2008 to July 2010) which included 50 living-related renal transplantations at Tribhuvan University Teaching Hospital. All the donors and recipients were evaluated preoperatively with necessary investigations and followed up postoperatively with standard hospital transplant protocol. The incidence of urological complications were documented and analyzed. Results Fifty living-related, renal transplantations were carried out during the study period. Seven doors had minor post operative complications; three had post operative fever, two had chest infections and each one had superficial surgical site infections and severe pain at incision site. Ureteroneocystostomy was performed with double J stent in all recipients. Urological complications were noted in 12 (24%) recipients. Clinical significant hematuria occurred in four cases. One patient had ureteric necrosis and urinary leak which required re-exploration post operatively. Two patients developed delayed ureteric stricture which were managed by antegrade Double J stenting and ureteric reimplantation. Peri-graft abscess occurred in two cases, which were drained percutaneously. surgical site infections was seen in one case. Conclusions Urological complications are inevitable in renal transplantation and our complications rate appears similar to that reported in literature. DOI: http://dx.doi.org/10.3126/kumj.v8i3.6216 Kathmandu Univ Med J 2010;8(3):299-304
Epistaxis in Visceral Leishmaniasis with Hematological Correlation
B. Sigdel,S. Bhandary,S. Rijal
International Journal of Otolaryngology , 2012, DOI: 10.1155/2012/809056
Abstract: Objective. To study the prevalence of epistaxis in visceral leismaniasis and its correlation with hematological profile. Methods. Out of 80 diagnosed cases of visceral leishmaniasis, 19 patients with epistaxis were included in the study. Diagnosis was made by Rk-39 from peripheral smear and LD bodies from bone marrow. Before starting anti-kala-azar treatment, nasal examination findings and hematological profile were noted. Study Design. Prospective cross-sectional hospital-based study. Results. Epistaxis was found in the age group of 7–66 years. Epistaxis was observed in 19 (23.8%) cases. One patient died because of epistaxis and neck hematoma. Conclusion. Epistaxis is a common ENT finding in endemic area of visceral leishmaniasis like our case.
Epistaxis in Visceral Leishmaniasis with Hematological Correlation
B. Sigdel,S. Bhandary,S. Rijal
International Journal of Otolaryngology , 2012, DOI: 10.1155/2012/809056
Abstract: Objective. To study the prevalence of epistaxis in visceral leismaniasis and its correlation with hematological profile. Methods. Out of 80 diagnosed cases of visceral leishmaniasis, 19 patients with epistaxis were included in the study. Diagnosis was made by Rk-39 from peripheral smear and LD bodies from bone marrow. Before starting anti-kala-azar treatment, nasal examination findings and hematological profile were noted. Study Design. Prospective cross-sectional hospital-based study. Results. Epistaxis was found in the age group of 7–66 years. Epistaxis was observed in 19 (23.8%) cases. One patient died because of epistaxis and neck hematoma. Conclusion. Epistaxis is a common ENT finding in endemic area of visceral leishmaniasis like our case. 1. Introduction Leishmaniasis refers to the spectrum of diseases caused by Leishmania species, which are Protozoa of order Kinetoplastida. Clinically leishmaniasis is divided into visceral (kala-azar), cutaneous, mucosal, and mucocutaneous syndromes and PKDL. Kala-azar is most commonly caused by L. donovani, L. infantum, and L. chagasi [1–3]. Visceral leishmaniasis has been reported from >60 countries [3]. An estimated 500?000 persons are affected by visceral leishmaniasis every year worldwide. The vast majority of these cases (90%) occur in poor rural area of India, Bangladesh, Sudan, Brazil, and Nepal [4, 5]. L. donovani is responsible for visceral leishmaniasis in eastern India, Bangladesh, Nepal, and vast areas of East Africa [1, 3]. Visceral leishmaniasis (VL) is a major public health problem in Nepal. The disease is endemic in twelve terai districts of eastern and southern Nepal. It is estimated that more than 6 million people in Nepal are at risk of leishmania infection [1]. Different otorhinolaryngological manifestations are seen in leishmaniasis. One of the common findings is epistaxis. Prevalence of epistaxis in visceral leishmaniasis up to 51% was found in Sudan and the Mediterranean littoral area [6]. The exact prevalence and cause of epistaxis was not clear in our setup. This study was done to find out the prevalence and hematological risk factor of epistaxis among VL patients. 2. Materials and Methods This study was conducted at Department of Otolaryngology and Head and Neck Surgery and Department of Internal Medicine in B. P. Koirala Institute of Health Sciences Dharan, Nepal over a period of one year from January 2007 to January 2008. It was a hospital-based prospective cross-sectional study. The total of 80 cases of VL was followed in the study period. VL was diagnosed based on clinical profile
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