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Search Results: 1 - 10 of 1212 matches for " MK Shrestha "
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Clinical Profile of Paediatric Cataract and Surgery in a Tertiary Eye Care Centre, Nepal
UD Shrestha,MK Shrestha
Journal of Nepal Paediatric Society , 2012, DOI: 10.3126/jnps.v32i1.5378
Abstract: Introduction: Paediatric cataract is the opacification of lens and its capsule in children below 14 years of age. The management of paediatric cataract is lens aspiration with or without anterior vitrectomy, with or without intra-ocular lens implantation. The objective was to present the profile of pediatric cataract of operated eyes in children ≤14 years.
Bruckner Red Light Reflex Test in a Hospital Setting
R Saiju,S Yun,PD Yoon,MK Shrestha,UD Shrestha
Kathmandu University Medical Journal , 2012, DOI: 10.3126/kumj.v10i2.7338
Abstract: Background Childhood blindness is a major problem in developing world including Nepal that needs to be addressed.
Outcome of pneumatic retinopexy at a tertiary eye care centre in Nepal
R Thapa,MK Shrestha,R Gurung,S Ruit,G Paudyal
Kathmandu University Medical Journal , 2008, DOI: 10.3126/kumj.v6i4.1737
Abstract: Normal 0 false false false MicrosoftInternetExplorer4 st1\:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable{mso-style-name:"Table Normal";mso-tstyle-rowband-size:0;mso-tstyle-colband-size:0;mso-style-noshow:yes;mso-style-parent:"";mso-padding-alt:0cm 5.4pt 0cm 5.4pt;mso-para-margin:0cm;mso-para-margin-bottom:.0001pt;mso-pagination:widow-orphan;font-size:10.0pt;font-family:"Times New Roman";mso-ansi-language:#0400;mso-fareast-language:#0400;mso-bidi-language:#0400;} Background : Rhegmatogenous retinal detachment is one of the commonly encountered retinal problems where timely treatment could prevent irreversible vision loss. Pneumatic retinopexy (PR) is a simple and minimally invasive procedure for retinal reattachment. Aim : This study aimed to assess the outcome of pneumatic retinopexy in primary rhegmatogenous retinal detachment at our facility. Study design : This was a retrospective- prospective, interventional case series. Materials and methods : All subjects with rhegmatogenous retinal detachment who underwent pneumatic retinopexy at Tilganga Eye Centre of Nepal from January 2002 to June 2007 were included in this study. Results : A total of 32 cases were included in the study. The mean age of patients was 55.2 year (SD=11.0). The majority of cases (62.5%) presented within two weeks of symptoms with blurring of vision in 90% of cases. Pre-operatively, 56.3% (18) patients had a best corrected distance visual acuity of Conclusion : The anatomical success rate following pneumatic retinopexy is quite high (81.3%) with good visual recovery and less morbidity translating to higher productivity for the patient. This procedure, being quicker than the alternatives, will also save surgeon's time making PR a good choice for managing primary rhegmatogenous retinal detachment in countries like Nepal where resources are scarce. Key words : Rhegmatogenous retinal detachment, retinal break, pneumatic retinopexy, Nepal ? doi: 10.3126/kumj.v6i4.1737 ? Kathmandu University Medical Journal (2008), Vol. 6, No. 4, Issue 24, 466-471 ?
Bleeding Meckel's Diverticulum in an Infant - A Case Report
MK Shrestha,RL Gurubacharya,K Devkota,N Agarwal
Journal of Nepal Paediatric Society , 2014, DOI: 10.3126/jnps.v34i1.9523
Abstract: Meckel’s diverticulum is a congenital diverticulum. Mostly it is asymptomatic. In children the commonest complication is lower GI bleeding. High index of suspicion is required for its diagnosis. Technetium-99m pertechnetate scan is useful to detect ectopic gastric mucosa. Surgical treatment of symptomatic Meckel’s diverticulum is diverticulectomy or ileal resection. DOI: http://dx.doi.org/10.3126/jnps.v34i1.9523 J Nepal Paediatr Soc 2014;34(1):54-56
Comparison of the Anomaly of Hydrological Analysis Tools used in Nepal
MK Shrestha,S Chaudhary,RK Maskey,G Rajkarnikar
Journal of Hydrology and Meteorology , 2010, DOI: 10.3126/jhm.v7i1.5614
Abstract: The diverse physiographic and hydrological regime has booned Nepal with high potential of water resource projects. But these projects depend highly on hydrological data for which hydrometeorological stations need to be established. Their establishment, because of difficult topographic feature of Nepal and the high cost of installation, operation and maintenance, becomes feasible only for big projects. And thus hydrological data are needed to be predicted for small scale projects. These predictions for a given ungauged river system at particular location are facilitated by empirical methods such as WECS/DHM (Water and Energy Commission Secretariat/ Department of Hydrology and Meteorology) and MIP (Medium Irrigation Project) which have been used since its development without upgrading and checking its reliability. The objective of this study is to compare the anomaly of flow predicted by WECS/DHM and MIP method and determine reliability of minimum flow predicted by the methods. The anomaly of the method is presented by comparing the mean DHM monthly flow with the mean of predicted monthly flow for each of the seven rivers from Central and Western Development Region. Both methods give variable deviation for different periods of time for all the rivers. MIP method gives reliable prediction only if the discharge measurement is done during the dry period (November–April). The reliability of these methods is checked for estimating minimum flow by calculating the percentage of time discharge (minimum predicted flow) will be exceeded. WECS/DHM has given higher reliability for the minimum flow than MIP method. MIP (D) method has given good approximation to the DHM dry period flow than MIP (A). While analyzing the low flow, lower predicted value given by either of these methods when used gives good approximation. In order to improve the accuracy of prediction there is requirement of modification of these Hydrological Analytical tools. Keywords: hydrological data; WECS/DHM method; MIP method; ungauged river; MIP (D); MIP (A) DOI: http://dx.doi.org/10.3126/jhm.v7i1.5614 JHM 2010; 7(1): 30-39
Utility of fine needle aspiration cytology in metastatic lymph nodes
D Ghartimagar,A Ghosh,S Ranabhat,MK Shrestha,R Narasimhan,OP Talwar
Journal of Pathology of Nepal , 2011, DOI: 10.3126/jpn.v1i2.5399
Abstract: Background: Fine needle aspiration cytology is a reliable as well as an inexpensive diagnostic method. It is suitable for the developing countries like Nepal for the diagnosis of lymphadenopathy at any approachable site. Fine needle aspiration cytology not only confirms the presence of metastatic disease but also, in most cases, gives the clue regarding the origin of the primary tumor. The aim of the study was to find out the cytological diagnosis of metastatic lymph node lesions. Materials and Methods: A combined prospective and retrospective study was done of all metastatic lymph node lesions (including both superficial and deep nodes) reported in Department of Pathology, Manipal Teaching Hospital, Pokhara from January 2005 to Deceember 2010. Results: A total of 4180 cases of fine needle aspiration cytology were carried out of which 508 cases were of lymph node. Cytology results were unsatisfactory in 58 specimens (12%), “reactive” or “infective” in 347 specimens (68%), positive for metastasis in 93 specimens (18%) and hematolymphoid malignancies include 10 cases (2%). The most common site was anterior and posterior triangles cervical nodes. The most common malignancy was adenocarcinoma, seen in 62 cases (67%), followed by metastatic squamous cells carcinoma (14 cases, 15%). Conclusion: Fine needle aspiration cytology of lymphadenoathy is a useful tool in diagnosing metastatic lesions with good certainty. Keywords: Fine needle aspiration cytology; Lymphadenopathy; Metastasis DOI: http://dx.doi.org/10.3126/jpn.v1i2.5399 JPN 2011; 1(2): 92-95
Comparative prevalence of MRSA in two Nepalese tertiary care hospitals  [PDF]
Bidya Shrestha
Open Journal of Clinical Diagnostics (OJCD) , 2013, DOI: 10.4236/ojcd.2013.32013
Abstract: This comparative study has been focused on the prevalence of MRSA types and their antibiotic resistance in two tertiary care hospitals of Nepal. During November 2007 to June 2009, clinical samples from patients with nosocomial infection from two Nepali hospitals, Kathmandu Based Hospital (KBH) and Lalitpur Based Hospital (LBH) were cultured and antibiotic susceptibility tests done following standard methodology in Microbiology laboratory, Tribhuvan University Teaching Hospital, Kathmandu, Nepal. Occurrence of MRSA (52.9% of 304 Staphylococcus aureus isolates) in KBH and that of MSSA (62% of 100 S. aureus isolates) in LBH were significant. No association of age was observed with MRSA or MSSA. Among MSSA from both hospitals, the highest resistance was found against penicillin. KBH urinary isolates were resistant to norfloxacin (51.4%), while isolates from other sites were resistant to ciprofloxacin (30.6%), erythromycin (12%), gentamicin (10.3%). LBH isolates were resistant to co-trimoxazole (22.6%), erythromycin (17.2%), ciprofloxacin (13.8%), gentamicin (12.9%). Among MRSA, most of the isolates from both hospitals were resistant to a wide array of antibiotics. A majority of the MSSA and MRSA isolates were susceptible to rifampicin and chloramphenicol. Most of KBH MRSA were homogeneous MRSA, 80.5% (significant), of which, 99.2% were multiresistant oxacillin resistant S. aureus (MORSA). And among the heterogeneous MRSA isolates from KBH, 71% were MORSA. On the other hand, among LBH MRSA isolates, 52.6% were homogeneous MRSA, cent percent of which were MORSA while 47.4% were heterogeneous MRSA of which 44.5% were MORSA. Since almost all of the homogeneous MRSA and most of the heterogeneous MRSA from both hospitals were MORSA, there is a possibility that a hospital acquired S. aureus could be MORSA. Hence, every infected patient should be considered as a potential source of MORSA.
Perioperative Management of Case of Gynecological Malignancy with Bilateral Deep Venous Thrombosis of Lower Limbs Along with Pulmonary Embolism  [PDF]
MK Arora, Rakesh Garg
Open Journal of Anesthesiology (OJAnes) , 2011, DOI: 10.4236/ojanes.2011.11001
Abstract: We describe the anaesthetic management of 45 year female patient with pre-existing deep venous thrombosis (DVT) and pulmonary embolism (PE) who was subsequently scheduled for an laparotomy. Before planning the surgical procedures, adequate anticoagulation must be achieved to prevent further complications of DVT, thromboembolism, and pulmonary embolism in particular. The risk of stopping the anticoagulation prior to surgery must be considered and adequately discussed with the patient and surgeons. The anaesthetic plan must be selected keeping in mind the coagulation status and the need of anticoagulation in the postoperative period.
Long Lead-Time Streamflow Forecasting Using Oceanic-Atmospheric Oscillation Indices  [PDF]
Niroj Kumar Shrestha
Journal of Water Resource and Protection (JWARP) , 2014, DOI: 10.4236/jwarp.2014.66062

Climatic variability influences the hydrological cycle that subsequently affects the discharge in the stream. The variability in the climate can be represented by the ocean-atmospheric oscillations which provide the forecast opportunity for the streamflow. Prediction of future water availability accurately and reliably is a key step for successful water resource management in the arid regions. Four popular ocean-atmospheric indices were used in this study for annual streamflow volume prediction. They were Pacific Decadal Oscillation (PDO), El-Nino Southern Oscillation (ENSO), Atlantic Multidecadal Oscillation (AMO), and North Atlantic Oscillation (NAO). Multivariate Relevance Vector Machine (MVRVM), a data driven model based on Bayesian learning approach was used as a prediction model. The model was applied to four unimpaired stream gages in Utah that spatially covers the state from north to south. Different models were developed based on the combinations of oscillation indices in the input. A total of 60 years (1950-2009) of data were used for the analysis. The model was trained on 50 years of data (1950-1999) and tested on 10 years of data (2000-2009). The best combination of oscillation indices and the lead-time were identified for each gage which was used to develop the prediction model. The predicted flow had reasonable agreement with the actual annual flow volume. The sensitivity analysis shows that the PDO and ENSO have relatively stronger effect compared to other oscillation indices in Utah. The prediction results from the MVRVM were compared with the Support Vector Machine (SVM) and the Artificial Neural Network (ANN) where MVRVM performed relatively better.

Tracking immune responses in vivo
MK Jenkins
Arthritis Research & Therapy , 2005, DOI: 10.1186/ar1510
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