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Search Results: 1 - 10 of 626 matches for " MH Stefanazzi "
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Liquen escleroso extragenital ampollar y hemorrágico: a propósito de un caso Extra-genital bullous and haemorrhagic lichen sclerosus: a case report
JM López Bertrán,FM Renis,MH Stefanazzi,C Simionato
Revista Argentina de Dermatología , 2010,
Abstract: El liquen escleroso (LE) es una enfermedad inflamatoria, crónica y benigna. De etiología desconocida, se ha vinculado con diversos factores autoinmunológicos, genéticos, hormonales, infecciosos y traumáticos. Hay dos variedades clínicas de esta enfermedad: genital y extra-genital. La localización más frecuente en ambos sexos es la genital. Se presenta un caso clínico de LE extra-genital, con lesiones cutáneas poco frecuentes, ampollares y hemorrágicas, que coexistían con placas atróficas de larga evolución, no diagnosticadas previamente. Lichen sclerosus is an inflammatory disease, benign, chronic, of unknown aetiology. It has been linked with many factors such as autoimmune, genetic, hormonal and infectious diseases, as well as trauma. There are two clinical types of this disease: genital and extra-genital. The most frequent in both sexes is the genital form. We present a rare case of extra-genital localization with bullous and haemorrhagic manifestations that co-existed with late atrophic plaques, previously undiagnosed.
Liquen escleroso extragenital ampollar y hemorrágico: a propósito de un caso
López Bertrán,JM; Renis,FM; Stefanazzi,MH; Simionato,C; Saponaro,AE; Vigovich,F; Casas,JG;
Revista argentina de dermatolog?-a , 2010,
Abstract: lichen sclerosus is an inflammatory disease, benign, chronic, of unknown aetiology. it has been linked with many factors such as autoimmune, genetic, hormonal and infectious diseases, as well as trauma. there are two clinical types of this disease: genital and extra-genital. the most frequent in both sexes is the genital form. we present a rare case of extra-genital localization with bullous and haemorrhagic manifestations that co-existed with late atrophic plaques, previously undiagnosed.
A case of a unilateral unusual genicular branch of the common peroneal nerve with bilateral high division of sciatic nerves and unusual bilateral thickness of peroneal communicating nerve
Ali MH,Eweidah MH
International Journal of Anatomical Variations , 2010,
Abstract: On dissection of an adult male Filipino cadaver, an unusual genicular branch from the left common peroneal nerve was found terminating in the capsule of the knee joint. Extra care by the surgeon is required to separate this variant nerve from the small saphenous vein and intraneural ganglion during knee operation. A bilateral higher division of the sciatic nerve was observed below the lower border of piriformis muscle. In the cases of popliteal blockage, the knowledge of the variations in the bifurcation of the sciatic nerve is significant. Bilateral thick communicating peroneal nerves were dissected. The sural nerves were very much reduced in size and communicating peroneal nerves largely replaced the innervations in the lower legs. This finding is important because of its use in nerve transplantation. In this case, the presence of an unusual genicular branch is a rare finding. In combination with the other stated findings in the same cadaver makes it interesting.
A Study of the One- Year Survival Rate of Patients with Acute Myocardial Infarction
MH Soltani,MH Ahmadieh
Journal of Shahid Sadoughi University of Medical Sciences , 2004,
Abstract: Introduction :Acute myocardial infarction (AMI) is the most common cause of death in many countries, and also one of the common causes of death in Iran. As the death rate due to AMI is not clear and the survival rate of these patients had not yet been studied in the city of Yazd, this study was undertaken. Methods and materials : This was a survival study performed in Yazd between the years 2000 and 2002. 210 patients with definite AMI (according to clinical findings, ECG and enzyme criteria) were enrolled in this study (case series). They were admitted to Shahid Rahnemoon Hospital of Yazd (A general hospital). Results : The population under study included 161 males with mean age of 59 14 years and 59 females with mean age of 66 10 years. Frequency of hypertension, diabetes mellitus, hypercholestrolemia, hypertriglyceridemia and smoking was 27%, 22%, 20%, 22% and 32%, respectively. All risk factors except smoking were more common in females than men. 83.3% of infarctions were Q-wave infarctions, 16.7% non- Q-wave infarctions. 53% inferior wall and 40% were anterior wall infarctions. Infusion of streptokinase was done for 62% of patients. Mean ejection fraction of left vantricle was 48% in males and 45% in females. In-hospital mortality rate was 12.4% and higher in patients older than 70 years, diabetics, and anterior wall infarction patients. It had no correlation with sex. Surprisingly, smoking was accompanied with a very low in-hospital mortality rate. Conclution : One – year mortality rate of the patients in this study was 16.7% . It was higher in females, diabetics, anterior wall infarction patients and those with an ejection fraction less than 45%. The one year mortality rate in smokers was comparitively lower than non smokers in this study.
Biological Activity of Essential Oils from Leaves and Fruits of Pepper Tree (Schinus molle L.) to Control Rice Weevil (Sitophilus oryzae L.)
Benzi,Verónica; Stefanazzi,Natalia; Ferrero,Adriana A;
Chilean journal of agricultural research , 2009, DOI: 10.4067/S0718-58392009000200004
Abstract: rice weevil (sitophilus oryzae l.) is a primary insect pest of stored grain. the development of resistance resulted in the application of synthetic insecticides. in recent years many plant essential oils have provided potential alternatives to currently used insect control agents. the brazilian pepper tree (schinus molle l. var. areira (l.) dc.) (anacardiaceae) has different biological properties such as insecticidal activity. in this study, repellent, fumigant activity, nutritional indices, and feeding deterrent action were evaluated on s. oryzae adults. filter paper impregnation was used to test fumigant toxicity, whereas treated whole wheat was used to evaluate repellent activity and a flour disk bioassay was done to evaluate feeding deterrent action and nutritional index alteration. leaf essential oils showed repellent effects at both concentrations (0.04 and 0.4% w/w), while fruit essential oils lacked repellent activity. both plant oils altered nutritional indices. fruit essential oils had a strong feeding deterrent action (62%) while leaves had a slight effect (40.6%). with respect to fumigant activity, neither of the essential oils was found to be toxic.
Biological Activity of Essential Oils from Leaves and Fruits of Pepper Tree (Schinus molle L.) to Control Rice Weevil (Sitophilus oryzae L.) Bioactividad de aceites esenciales de hojas y frutos del aguaribay (Schinus molle L.) en el gorgojo del arroz (Sitophilus oryzae L.)
Verónica Benzi,Natalia Stefanazzi,Adriana A Ferrero
Chilean Journal of Agricultural Research , 2009,
Abstract: Rice weevil (Sitophilus oryzae L.) is a primary insect pest of stored grain. The development of resistance resulted in the application of synthetic insecticides. In recent years many plant essential oils have provided potential alternatives to currently used insect control agents. The Brazilian pepper tree (Schinus molle L. var. areira (L.) DC.) (Anacardiaceae) has different biological properties such as insecticidal activity. In this study, repellent, fumigant activity, nutritional indices, and feeding deterrent action were evaluated on S. oryzae adults. Filter paper impregnation was used to test fumigant toxicity, whereas treated whole wheat was used to evaluate repellent activity and a flour disk bioassay was done to evaluate feeding deterrent action and nutritional index alteration. Leaf essential oils showed repellent effects at both concentrations (0.04 and 0.4% w/w), while fruit essential oils lacked repellent activity. Both plant oils altered nutritional indices. Fruit essential oils had a strong feeding deterrent action (62%) while leaves had a slight effect (40.6%). With respect to fumigant activity, neither of the essential oils was found to be toxic. El gorgojo del arroz (Sitophilus oryzae. L.) es un insecto-plaga de infestación primaria de granos. El uso de insecticidas sintéticos ha desarrollado fenómenos de resistencia. En los últimos a os los aceites esenciales se presentan como una alternativa en el control de insectos-plaga. El aguaribay (Schinus molle L. var. areira (L.) DC.) (Anacardiaceae) es una planta con diferentes propiedades biológicas entre las que se destacan el uso como insecticida. El objetivo de este estudio fue evaluar la actividad fumigante, repelente, los índices nutricionales y la actividad antialimentaria de los aceites esenciales de hojas y frutos de S. molle var. areira en adultos de S. oryzae. Para la actividad fumigante se utilizó la técnica de impregnación de papeles de filtro; para la actividad repelente impregnación de trigo entero; y para los índices nutricionales y la actividad antialimentaria impregnación de discos de harina de trigo. El aceite esencial de hojas mostró efectos repelentes a ambas concentraciones (0,04 y 0,4% p/v), mientras que el de frutos no produjo repelencia. Ambos aceites alteraron la fisiología nutricional de S. oryzae. El aceite de frutos produjo un efecto antialimentario fuerte (62%) y el de hojas leve (40,6%). No se observó actividad fumigante.
Multiresistant bacteria and current therapy - the economical side of the story
MH Wilke
European Journal of Medical Research , 2010, DOI: 10.1186/2047-783x-15-12-571
Abstract: In a systematic review of the literature the following aspects were investigated:- Do generic treatment strategies contribute in cost savings?- Are there specific results for recent antibiotics?Early adequate and effective antimicrobial treatment, switch from i.v. to oral therapy, adjusted duration of therapy and adherence to guidelines have been found to be successful strategies.Looking at specific antibiotics, the best evidence for cost-effectiveness is found for Linezolid in treatment of cSSTI as well as in HAP. Daptomycin shows good economic results in bloodstream infections, so possibly being a cost-effective alternative to vancomycin. Looking at tigecycline the published data show neither higher costs nor savings compared to imipeneme. Doripenem as one of the newest therapy options has proven to be highly cost-saving in HAP when compared with imipenem. However, most analyses are based on pharmacoeconomic modelling rather than on directly analysing trial data or real life clinical populations.Using modern antibiotics in whole is not more expensive than using established therapies. Modern antibiotics are cost-effective and sometimes even cost-saving. This is especially true if an effective therapy is initiated as early as possible.Severe MRB cause a serious burden of disease in most countries worldwide [1,2,6,23]. Their therapeutic management is a major cost driver in healthcare, particularly in hospitals. Looking at the economical impact of antibiotic therapy of severe MRB infections, several factors were identified as the major cost drivers [3-5]:- prolonged hospital length of stay (LOS)- hours of mechanical ventilation (HMV)- duration of treatment on an intensive care unit (ICU)- cost of patient isolation (isolation)- complications, such as renal failure or infection transmissionWhether any given antibiotic therapy is an economically adequate option therefore depends on its effect on one or more of these cost drivers. Interestingly, the actual daily costs of
Treatment and prophylaxis of invasive candidiasis with anidulafungin, caspofungin and micafungin and its impact on use and costs - review of the literature
MH Wilke
European Journal of Medical Research , 2011, DOI: 10.1186/2047-783x-16-4-180
Abstract: While the individual echinocandin antifungals have a different spectrum of licensed indications, basically all of them are available for the treatment of candidemia and invasive candidiasis. Antifungal treatment modalities basically include in therapy for suspected or proven infection and prophylaxis. All three drugs are comparatively expensive. Therefore a systematic review of the literature was performed to investigate the following aspects:? General aspects of cost-effectiveness in the treatment of invasive fungal infections? Cost-effectiveness of the treatment with the above-mentioned antifungals? Cost-effectiveness in two settings: therapy and prophylaxisEarly initiation of antifungal therapy, adjustment after availability of microbiological results, duration of therapy, success and occurrence of severe complications (e.g renal failure) are the most important cost drivers in antifungal therapy.Considering the specific antifungals, for caspofungin the best evidence for cost-effectiveness is found in treatment of invasive candidiasis and in empiric therapy of suspected infections. Favourable economic data are available for micafungin as a cost-effective alternative to LAmB for prophylaxis in patients with hematopoietic stem cell transplantation (HSCT). For anidulafungin, cost-effectiveness was demostrated in a pharmacoeconomic model. Net savings - yet not significant - were observed in a retrospective chart review of 234 patients. Generally, however, most analyses are still based on pharmacoeconomic modelling rather than direct analysis of trial data or real-life clinical populations.As an overall conclusion, using caspofungin, micafungin, or anidulafungin is not more expensive than using other established therapies. Micafungin has proven to be cost-effective in prophylaxis if the local fungal epidemiology indicates a high level of resistance to fluconazole. Switch strategies involving early initiation of broadly active therapy with switch to cheaper alternatives
Preventing cervical cancer
MH Botha
Continuing Medical Education , 2009,
Abstract: Cervical cancer remains the most common cancer diagnosed in women in southern Africa, with an estimated lifetime risk of 1 in 26.1 Unfortunately most of these cancers are also diagnosed at late stage, with subsequent poor prognosis for long-term survival. This very high incidence is particularly sad in an era where advances in medical science have made cervical cancer a mostly preventable disease. In most developed economies cervical cancer has become a less common occurrence due to intensive screening and preventive strategies.
Cryobanking: the brave new world of biobanking and specimen cryopreservation
Bluth MH
Journal of Biorepository Science for Applied Medicine , 2012, DOI: http://dx.doi.org/10.2147/BSAM.S29906
Abstract: Cryobanking: the brave new world of biobanking and specimen cryopreservation Editorial (1229) Total Article Views Authors: Bluth MH Published Date June 2012 Volume 2012:1 Pages 1 - 3 DOI: http://dx.doi.org/10.2147/BSAM.S29906 Received: 10 April 2012 Accepted: 11 April 2012 Published: 11 June 2012 Martin H Bluth Department of Pathology, Wayne State University School of Medicine, Detroit Medical Center, Karmanos Cancer Institute, Detroit, MI, USA The layperson’s depiction of people preservation often conjures up nefarious iterations of Jack Finney’s 1954 novel, The Body Snatchers, or Ira Levin’s thriller, The Boys from Brazil, where maintenance of human composition is employed for perpetuation of ill repute. Recent illustrations of animal preservation-reanimation gone wrong, such as the Jurassic Park films, further echoed such concerns. In contrast, during the 1980s, the advent of cloning morphed with cryopreservation to furnish jocularity in the form of many an Arnold Schwarzenegger film (Twins, Junior). The late 1980s and early 1990s also demonstrated a greater degree of reality-based cryopreservation, public acceptance, and clinical application in the form of cord blood-banking, stem cell transplantation, and in-situ fertilization technologies, thus positively affecting both the biobanking image and human health.1 Post to: Cannotea Citeulike Del.icio.us Facebook LinkedIn Twitter Other articles by Dr Martin Bluth Characterization of overactive bladder in women in a primary care setting Peripheral blood mononuclear cell gene array profiles in female patients with involuntary bladder contractions Pharmacogenomics of drug metabolizing enzymes and transporters: implications for cancer therapy Readers of this article also read: Performance in L1 and L2 observed in Arabic-Hebrew bilingual aphasic following brain tumor: A case constitutes double dissociation Local anesthetic failure associated with inflammation: verification of the acidosis mechanism and the hypothetic participation of inflammatory peroxynitrite Evidence-based decision-making within the context of globalization: A “Why–What–How” for leaders and managers of health care organizations The cognitive basis of diglossia in Arabic: Evidence from a repetition priming study within and between languages Neurotransmitter testing of the urine: a comprehensive analysis Epigenomics in cancer management Amino acid-responsive Crohn's disease: a case study Evaluation of in-vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferi Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor Radio electric asymmetric brain stimulation in the treatment of behavioral and psychiatric symptoms in Alzheimer disease
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