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Search Results: 1 - 10 of 400870 matches for " M; MORELLO "
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Charmless b-hadrons decays at CDF
M. J. Morello,for the CDF collaboration
Physics , 2008,
Abstract: We present CDF results on the branching fractions and time-integrated direct CP asymmetries for Bd, Bs and Lb decay modes into pairs of charmless charged hadrons (pions, kaons and protons). The data-set for these measurements amounts to 1fb^{-1} of pbar-p collisions at a center of mass energy 1.96TeV. We report on the first observation of the Bs->Kpi, Lb-ppi and Lb->pK decay modes and on the measurement of their branching fractions and direct CP asymmetries.
Una encrucijada de caminos: el poblamiento de la Isla Dawson (Estrecho de Magallanes)
LEGOUPIL,D; CHRISTENSEN,M; MORELLO,F;
Magallania (Punta Arenas) , 2011, DOI: 10.4067/S0718-22442011000200010
Abstract: a research about the role of prehistoric human peopling of dawson island, central magellan strait zone, is presented through the discussion of data collected in an extensive survey that included the eastern shoreline of the island and its comparison with other canoe core areas. the discovery of 29 archaeolo-gical sites permitted recording unknown evidence of human occupations dating between ca. 4200 and 1200 years bp. they could represent a step between the two southernmost maritime population cores of otway sound/ brunswick peninsula and beagle channel.
Una encrucijada de caminos: el poblamiento de la Isla Dawson (Estrecho de Magallanes) A crossroad: the peopling of Dawson Island (Magellan Strait)
D LEGOUPIL,M CHRISTENSEN,F MORELLO
Magallania , 2011,
Abstract: Se presenta un estudio sobre el rol del poblamiento humano prehistórico de isla Dawson, zona central del estrecho de Magallanes, a través de la discusión de los resultados recopilados en una extensa prospección que abarcó la costa este de la isla y su comparación con otros núcleos canoeros. El descubrimiento de 29 sitios arqueológicos permitió registrar evidencias inéditas de ocupaciones humanas datadas entre ca. 4200 y 1200 a os A P. Podrían representar un vínculo entre los dos núcleos de poblamiento canoero de la zona austral, el mar de Otway/península Brunswick y el canal Beagle. A research about the role of prehistoric human peopling of Dawson Island, central Magellan strait zone, is presented through the discussion of data collected in an extensive survey that included the eastern shoreline of the island and its comparison with other canoe core areas. The discovery of 29 archaeolo-gical sites permitted recording unknown evidence of human occupations dating between ca. 4200 and 1200 years BP. They could represent a step between the two southernmost maritime population cores of Otway Sound/ Brunswick Peninsula and Beagle Channel.
The Resistive-WELL detector: a compact spark-protected single amplification-stage MPGD
G. Bencivenni,R. De Oliveira,G. Morello,M. Poli Lener
Physics , 2014, DOI: 10.1088/1748-0221/10/02/P02008
Abstract: In this work we present a novel idea for a compact spark-protected single amplification stage Micro-Pattern Gas Detector (MPGD). The detector amplification stage, realized with a structure very similar to a GEM foil, is embedded through a resistive layer in the readout board. A cathode electrode, defining the gas conversion/drift gap, completes the detector mechanics. The new structure, that we call Resistive-WELL (R-WELL), has some characteristics in common with previous MPGDs, such as C.A.T. and WELL, developed more than ten years ago. The prototype object of the present study has been realized in the 2009 by TE-MPE-EM Workshop at CERN. The new architecture is a very compact MPGD, robust against discharges and exhibiting a large gain ($\sim$6$\times$10$^3$), simple to construct and easy for engineering and then suitable for large area tracking devices as well as huge calorimetric apparata.
Pharmacokinetics and pharmacodynamics of insulin analogs in special populations with type 2 diabetes mellitus
Morello CM
International Journal of General Medicine , 2011, DOI: http://dx.doi.org/10.2147/IJGM.S26889
Abstract: rmacokinetics and pharmacodynamics of insulin analogs in special populations with type 2 diabetes mellitus Review (5096) Total Article Views Authors: Morello CM Published Date December 2011 Volume 2011:4 Pages 827 - 835 DOI: http://dx.doi.org/10.2147/IJGM.S26889 Candis M Morello1,2 1Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 2School of Pharmacy, University of California San Francisco, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA Introduction: The goal of insulin therapy in patients with either type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) is to match as closely as possible normal physiologic insulin secretion to control fasting and postprandial plasma glucose. Modifications of the insulin molecule have resulted in two long-acting insulin analogs (glargine and detemir) and three rapid-acting insulins (aspart, lispro, and glulisine) with improved pharmacokinetic/pharmacodynamic (PK/PD) profiles. These agents can be used together in basal-bolus therapy to more closely mimic physiologic insulin secretion patterns. Methods: This study reviews effects of the multiple demographic and clinical parameters in the insulin analogs glargine, detemir, lispro, aspart, and glulisine in patients with T2DM. A search was conducted on PubMed for each major topic considered (effects of injection site, age, race/ethnicity, obesity, renal or hepatic dysfunction, pregnancy, exercise, drug interactions) using the topic words and name of each type of insulin analog. Information was also obtained from the prescribing information for each insulin analog. Results: The PK/PD profiles for insulin analogs may be influenced by many variables including age, weight, and hepatic and renal function. However, these variables do not have equivalent effects on all long-acting or rapid-acting insulin analogs. Conclusion: Rapid-acting and long-acting insulin analogs represent major advances in treatment for patients with T2DM who require insulin therapy. However, there are potentially important PK and PD differences between the two long-acting agents and among the three rapid-acting insulin analogs, which should be considered when designing treatment regimens for special patient groups.
Diversidade no Brasil: línguas e políticas sociais
Rosangela Morello
Synergies Brésil , 2009,
Abstract: Ce texte traite des politiques de soutien à la diversité au Brésil et montre les avancées et les défis qu′implique la prise en compte de la diversité linguistique. Dans le contexte actuel, les politiques publiques de soutien à la diversité sont considérées comme un facteur et un vecteur de l′équité sociale et de développement économique durable. On montrera que promouvoir le débat des langues non officialisées par l′Etat National participe de ce processus dans la mesure où s′établit alors une relation d′importance de la société avec les technologies de la communication et de l′information, ainsi que la possibilité pour les locuteurs de ces langues de se voir occuper de nouvelles places dans le dialogue politique institutionnel. Dans l′histoire du pays, ce débat met en lumière la pertinence à repenser les mécanismes de soutien et le changement possible des processus d′exclusion de nombreux groupes sociaux des espaces de participation et de représentation politique.
Pharmacokinetics and pharmacodynamics of insulin analogs in special populations with type 2 diabetes mellitus
Morello CM
International Journal of General Medicine , 2011,
Abstract: Candis M Morello1,21Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 2School of Pharmacy, University of California San Francisco, Veterans Affairs San Diego Healthcare System, San Diego, CA, USAIntroduction: The goal of insulin therapy in patients with either type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) is to match as closely as possible normal physiologic insulin secretion to control fasting and postprandial plasma glucose. Modifications of the insulin molecule have resulted in two long-acting insulin analogs (glargine and detemir) and three rapid-acting insulins (aspart, lispro, and glulisine) with improved pharmacokinetic/pharmacodynamic (PK/PD) profiles. These agents can be used together in basal-bolus therapy to more closely mimic physiologic insulin secretion patterns.Methods: This study reviews effects of the multiple demographic and clinical parameters in the insulin analogs glargine, detemir, lispro, aspart, and glulisine in patients with T2DM. A search was conducted on PubMed for each major topic considered (effects of injection site, age, race/ethnicity, obesity, renal or hepatic dysfunction, pregnancy, exercise, drug interactions) using the topic words and name of each type of insulin analog. Information was also obtained from the prescribing information for each insulin analog.Results: The PK/PD profiles for insulin analogs may be influenced by many variables including age, weight, and hepatic and renal function. However, these variables do not have equivalent effects on all long-acting or rapid-acting insulin analogs.Conclusion: Rapid-acting and long-acting insulin analogs represent major advances in treatment for patients with T2DM who require insulin therapy. However, there are potentially important PK and PD differences between the two long-acting agents and among the three rapid-acting insulin analogs, which should be considered when designing treatment regimens for special patient groups.Keywords: insulin analogs, type 2 diabetes mellitus, pharmacodynamics, pharmacokinetics
LOS CAZADORES DESPUéS DEL HIELO
Flavia Morello
Magallania , 2006,
Abstract:
El Concilio Vaticano II y su impacto en América Latina: a 40 a os de un cambio en los paradigmas en el catolicismo
Gustavo Morello
Revista mexicana de ciencias políticas y sociales , 2007,
Abstract: En este artículo, el autor examina el recorrido operado en la Iglesia católica durante el Concilio Vaticano II. La in- fluencia del Concilio en el catolicismo en esos a os ayuda a explicar el auge de los movimientos de izquierda en la América Latina de los a os sesenta. Se comienza rescatando algunos antecedentes que ayudan a entender mejor el cambio que significó el Concilio: los Pactos de Letrán, la Nouvelle Theologie, el movimiento ecuménico y por supuesto, el impacto de la segunda guerra en Europa. Asimismo, se analizan los rasgos del pensamiento cristiano que significaron un viraje en las posiciones de la iglesia y dejaron abierta la posibilidad de diálogo con el socialismo en general.
Quantum nanomagnets and nuclear spins: an overview
Andrea Morello
Physics , 2007, DOI: 10.1007/978-1-4020-8512-3_9
Abstract: This mini-review presents a simple and accessible summary on the fascinating physics of quantum nanomagnets coupled to a nuclear spin bath. These chemically synthesized systems are an ideal test ground for the theories of decoherence in mesoscopic quantum degrees of freedom, when the coupling to the environment is local and not small. We shall focus here on the most striking quantum phenomenon that occurs in such nanomagnets, namely the tunneling of their giant spin through a high anisotropy barrier. It will be shown that perturbative treatments must be discarded, and replaced by a more sophisticated formalism where the dynamics of the nanomagnet and the nuclei that couple to it are treated together from the beginning. After a critical review of the theoretical predictions and their experimental verification, we continue with a set of experimental results that challenge our present understanding, and outline the importance of filling also this last gap in the theory.
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