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Search Results: 1 - 10 of 496515 matches for " M.H EMAMI "
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HEPARIN THERAPY IN PATIENT WITH NON-Q WAVE MYOCARDIAL INFARCTION AND UNSTABLE ANGINA
M.H EMAMI,M HEKMAT
Journal of Research in Medical Sciences , 2000,
Abstract: Introduction. This study was conducted to find that, is there any advantage from (5000 IU/6h) in patient with non-Q wave MI and unastable angina. Methods. In a randomized clinical trial two group of patients with non-Q wave MI and unstable angina were compared about their prognosis and management outcomes. In interventional group (n= 145), heparin (5000 IU/6h) was administered and in another group (n= 133) no treatment with heparin was used. Duration of chest pain, recurrent angina, intrahospital mortality were indices for patients outcome study. Findings. Anticoagulant complication was not report in any patient in interventional group. There is no significant difference between two groups about prognosis factors. Conclusion. Heparin administration (5000 IU/6h) may have not any role in improving management outcome in patient with non-Q wave MI and unastable angina at least in acute phase. So, it is recommended that heparin have been administered to these patients in continuous regimen (1000-1500 U/hour continuously effusion).
KNOWN RISK FACTORS FOR RETINAL VEIN OCCLUSION: ITS DISTRIBUTION AMONG OUR COMMUNITY - IUMSHS (1999-2000)
M.H EMAMI,M KARIMIFAR,M VOSOUGHI,F FAZEL
Journal of Research in Medical Sciences , 2001,
Abstract: Introduction. Retinal vein occlusion (RVO) may lead to visual loss or even to blindness. RVO may accompany with most of systemic disease as well as some eye diseases. Since no effective treatment is known to restore the full vision in none of the cases, it is necessary to determine and identify the precipitating factors and to treat them in order to prevent the involvement of another eye. Methods. Among 2500 patients with chief complaint of visual loss 62 patients had retinal vessel occlusion, 59 patients (95 percent) had RVO and 3 patients (5 percent) had retinal artery occlusion (RAO). 3 patients with CRVO who didn"t fallow up were excluded the study. The necessary medical examinations were done in internal medicine clinic after primary examination in ophtalmology clinic and raw data were recorded in special form for each patient. Results. From 56 patients with RVO, 55.36 percent (31 subjects) were female and 44.64 percent (25 subjects) were male. 76.79 percent of patients (43 subjects) were 50 years or more and 66.1 percent (37 subjects) suffered from hypertension, 35.7 percent ( 20 subjects) had hypercholestrolemia ; and 21.4 percent (12 patients) had diabetes mellitus. 23.2 percent of patients (13 subjects) were previously smokers, 14.28 percent (8 subjects) were current smokers and the rest had quitted smoking. Totally, 37.5 percent of patients) were menopausal women. In 57.14 percent of the patients body mass index BMI) were higher than 24.9 Kg/m2.In 80.4 percent and 44.6 percent of the patients serum a2- globulin and ? globulion was higher than normal, respectively. Discussion. The data showed that most of the patients with RVO were more than 50 years old. Associated systemic risk factors in this study are listed bellow from the most to the least frequency order: hypertension, high 8MI, LDL hypercholestrolemia, diabetes mellitus and smoking.
Fabrication of yttria stabilized zirconia nanopowder via sol- gel rout
M.H Fathi,V Mortazavi,P Khodambashi Emami
Journal of Isfahan Dental School , 2008,
Abstract: Introduction: Yttria stabilized zirconia (YSZ) has been under consideration due to its desiredproperties for preparing dental restorations. The aim of this research was to produce the YSZnanopowder via sol-gel rout.Materials and methods: The present research was an experimental study and in vitro evaluation.Appropriate amount of zirconium oxide chloride, ZrOC12.8H2O, and yttrium nitrate,Y(NO3)3.6H2O, to reach 3mol% yttrium oxide in final product, were mixed in anhydrous ethanol ona magnetic stirrer. After drying the obtained gel at 50oC, it was calcined at 600oC for 1, 2 and 3hours. Phase identification, particle size and distribution determination, functional groupidentification and microstructural investigation were performed using XRD, SEM, TEM and FTIRtechniques.Results: Results revealed that the tetragonal zirconia phase nanopowder has been obtained.Crystallite size of the powder was about 20 nm and the size of particles was about 80 nm. Theoptimum temperature and time for calcimine process was 600oC and 3 hours, respectively.Conclusion: The obtained Yttria stabilized zirconia with special characteristics duo to nano scalestructure, could be a desired biomaterials for preparing dental restorations such as inlay, on lay, postand core, crown, and bridges in dentistryKeywords: Zirconia, Yttria stabilized zirconia, Zirconia nanopowder, Dental restoration
EMERGENCY SERVICES IN AN EDUCATIONAL HOSPITAL: WHERE ARE THE GOLDEN TIMES LOST?
M.H EMAMI,H.R ABTAHI,P BAHMAN ZIARI,M.R GHERAATI
Journal of Research in Medical Sciences , 2000,
Abstract: Introduction. Emergency Departments (EO) have a highly variable workload and need to highly expertise for a critical decision making in an emergency situation. This study was designed to find some of the golden times lost in AL-Zahra Emergency department (the greatest referral emergency center in Isfahan province, affiliated to Isfahan University of Medical Sciences and Health Services). Methods. In an observational study, we recorded all times spent by each 2212 patients referred to EO. The study was conducted in 30 days period (1999 June) and data was collected by full time secret observers. Results. About 55.1 percent of patients came by own and others were referred by physicians or other medical centers. Forty four percent of them were managed ambulatory. About half of the admissions were during 4 to 12 PM. Mean waiting times for each stage of patient management were as follows: waiting for patient's first visit by intern of screen room, 2 min; second visits by referral intern visit, 7 min; third visit by related resident, 37 min; patient arrival at EO. till admission, 41 min; hospital registration of patient, 11 min; ordering by intern or physician, 14 min; patient arrivalat EO. till ward admission, 189 min; performing procedures for outpatient's, 95 min; patient arrival at E.O. till receiving prescription (as an ambulatory care), 97 min. Mean waiting times for preclinical procedures were: EKG, 10 min; ultrasonography, 50 min; X-ray or CT scans, 36 min and lab tests, 117 min. About 51 percent of admissions were in field of internal medicine (including neurologic and infectious disease). In 88.8 percent of the admissions, physicians who were engaged in patient screening were not matched to their specialty and expertise. Primary diagnosis was correct in 31 percent and wrong in 6 percent of hospitalized patients. In 41 percent of cases, ultimate diagnosis was obscure. The average of CPR incidence was 2.7 times per day. Discussion. The most rate limiting stages in our E.O. were paraclinical procedures, making decision for admission and finally, registration process. Foremost of the cases, physicians who were engaged in screening process had not sufficient expertise in patient management due to inappropriate specialty and/or inadequate knowledge.
The potential inhibitory effect of cuminum cyminum, ziziphora clinopodioides and nigella sativa essential oils on the growth of Aspergillus fumigatus and Aspergillus flavus
Khosravi, A.R;Minooeianhaghighi, M.H;Shokri, H;Emami, S.A;Alavi, S.M;Asili, J;
Brazilian Journal of Microbiology , 2011, DOI: 10.1590/S1517-83822011000100027
Abstract: the goals of this study were to evaluate the effectiveness of cuminum cyminum, ziziphora clinopodioides and nigella sativa essential oils to inhibit the growth of aspergillus fumigatus and a. flavus and to evoke ultrastructural changes. the fungi were cultured into rpmi 1640 media in the presence of oils at concentrations of 8, 6, 5, 4, 3, 2, 1.5, 1.25, 1, 0.75 and 0.5 mg/ml in broth microdilution and 2, 1.5, 1 and 0.5 mg/ml in broth macrodilution methods with shaking for 48 h at 28oc. conidial and mycelial samples exposed to 0.25, 0.5, 1, 1.5 and 2 mg essential oils/ml for 5 days in 2% yeast extract granulated plus 15% saccharose media were processed for transmission electron microscopy (tem). based on broth dilution methods, c. cyminum and to a lesser extent z. clinopodioides oils exhibited the strongest activity against a. fumigatus and a. flavus with mic90 ranging from 0.25 to 1.5 mg/ml, while the oil from n. sativa exhibited relatively moderate activity against two above fungi with mic90 ranging from 1.5 to 2 mg/ml. the main changes observed by tem were in the cell wall, plasma membrane and membranous organelles; in particular, in the nuclei and mitochondria. these modifications in fungal structure were associated with the interference of the essential oils with the enzymes responsible for cell wall synthesis, which disturbed normal growth. moreover, the essential oils caused high vacuolation of the cytoplasm, detachment of fibrillar layer of cell wall, plasma membrane disruption and disorganization of the nuclear and mitochondrial structures. aspergillus fumigatus and a. flavus growth inhibition induced by these oils were found to be well-correlated with subsequent morphological changes of the fungi exposed to different fungistatic concentrations of the oils. our results show the anti-aspergillus activities of c. cyminum, z. clinopodioides and n. sativa essential oils, which strengthens the potential use of these substances as anti-mould in the future.
Amlodipine Reduce Pyrethroid Neurotoxicity in Mice
M.H. Khayatnouri
Research Journal of Biological Sciences , 2012, DOI: 10.3923/rjbsci.2011.678.681
Abstract: Permethrin a synthetic pyrethroid poisons are used as insecticide. These toxins can be used insecticides in agriculture and medicine for destruction and/or eradication of ectoparasites of animals. Studies have shown that Permethrin creation seizure effects in different animals. Amlodipine, calcium channel blocker, widely used for treatment of cardiovascular diseases. Studies have shown that the calcium channel blockers are anti-convulsant effects in different animal models. The aim of this study was to determine the effect of Amlodipine on Permethrin-induced seizures in mice. In this experiment, the animals were received different doses of Amlodipine (2.5, 5, 10, 20 and 40 mg kg-1 b.wt.) intraperitoneally 30 min before intraperitoneal injection of Permethrin (200 mg kg-1 b.wt). After Permethrin injection, clonic and tonic seizures and finally, death was the fate was investigated. Results showed that Amlodipine dose dependently reduced the severity of Permethrin-induced seizures so that Amlodipine at dose of 10 mg kg-1 (the lowest, p<0.05) and 40 mg kg-1 b.wt. (the highest, p<0.001) which had anti-convulsant effects. The anti-convulsant activity of Amlodipine suggests that possibly due to antagonistic effect on voltage-dependent calcium channel.
Anti-Convulsant Effect of Diltiazem on Lindane-Induced Toxicity in Mice
M.H. Khayatnouri
Research Journal of Biological Sciences , 2012, DOI: 10.3923/rjbsci.2011.666.669
Abstract: Lindane a synthetic organochlorate poisons are used as insecticide. These toxins can be used insecticides in agriculture and medicine for destruction and/or eradication of ectoparasites of animals. Studies have shown that Lindane creation seizure effects in different animals. Diltiazem, calcium channel blocker, widely used for treatment of cardiovascular diseases. Studies have shown that the calcium channel blockers are anti-convulsant effects in different animal models. The aim of this study was to determine the effect of Diltiazem on Lindane-induced seizures in mice. In this experiment, the animals were received different doses of Diltiazem (2.5, 5, 10, 20 and 40 mg kg-1 b.wt.) intraperitoneally 30 min before intraperitoneal injection of Lindane (50 mg kg-1 b.wt). After Lindane injection, clonic and tonic seizures and finally death was the fate was investigated. Results showed that Diltiazem dose dependently reduced the severity of Diltiazem-induced seizures so that Diltiazem at dose of 10 mg kg-1 (the lowest, p<0.05) and 40 mg kg-1 b.wt. (the highest, p<0.001) which had anti-convulsant effects. The anti-convulsant activity of Diltiazem suggests that possibly due to antagonistic effect on voltage-dependent calcium channel.
Responses of Different Wheat Genotypes to Drought Stress Applied at Different Growth Stages
M.H. Sangtarash
Pakistan Journal of Biological Sciences , 2010,
Abstract: Environmental stress especially drought stress can play an important role in the reduction of plant growth and development. In order to study the effects of drought stress on different growth stages of wheat, an experiment was conducted with five Iranian variety included Atrak, Red-Seed, Cross-Flat, Hirmand and Darab. A split plot design was used with drought treatment being the main plot and cultivar the subplot with three replications. Poorest yield were when drought stress was applied at flowering. It was shown that the most sensitive crop stage in terms of the total number of spikelets is at early stem elongation. Onset of the drought stress at flowering had the greatest damaging effect on seeds per spikelet. The most damaging to seed size was drought stresses applied at and just after flowering. Significant interactions occurred because Darab the highest yielding cultivar and Red-Seed the lowest yielding cultivar both showed an equal and great reduction in seed size under the drought stress while Hirmand was much less responsive. Morphological characters are likely to be affected by water stress. The results of this study indicate that if water for irrigation is scarce and needs to be conserve any saving should not be at the risk of causing drought stress around anthesis. Hirmand, while not the highest yielding cultivar is more stable over the range of moisture stresses applied and it could be considered as a parent to combine its stability with the higher yield potential of say, Darab.
Postsynaptic Alpha 2-Adrenoceptors Mediate Melanosome Aggregation in Melanophores of the White-Spotted Rabbitfish (Siganus canaliculatus)
M.H. Amiri
Pakistan Journal of Biological Sciences , 2009,
Abstract: The present investigation was undertaken to study the nature of neuro-melanophore junction in the white-spotted rabbit fish Siganus cancliculatus. In vitro experiments using split fin preparation indicated that melanophores of S. cancliculatus are highly responsive to potassium ions and adrenergic agonists. Potassium ions and the adrenergic agonists induced prompt melanosome aggregation that could be competitively blocked by yohimbine (alpha-2 specific adrenergic antagonist) and phentolamine (non-specific alpha adrenergic antagonist). The melanophore responses to repeated potassium stimulation (up to 20 stimuli) did not show any sign of fatigue. However, statistically significant enhancement was observed in responses to potassium that followed the first five stimulations. Adrenergic agonists acted in a time and concentration-dependent manner and their relative potency had the following rank order: clonidine (alpha-2 specific agonist) > norepinephrine (non-specific adrenergic agonist) > phenylephrine (alpha-1 specific agonist) > methoxamine (alpha-1-specific agonist). Yohimbine exerted a more potent inhibiting effect on norepinephrine induced melanosome aggregation compared to phentolamine. Prazosine (alpha-1 specific antagonist) had no effect on such aggregation. Chemically denervated melanophores displayed hypersensitivity to alpha-adrenergic agonists but were refractive to potassium ion stimulation. The refractivity of denervated melanophores to potassium indicates the effect of potassium ion is not direct on melanophores but it is rather through depolarization effect of potassium on the neuro-melanophore peripheral sympathetic fibers and hence release of norepinephrine. In denervated melanophores, similar to intact melanophores, only phentolamine and yohimbine but not prazosine, significantly inhibited melanosome aggregation effect of norepinephrine, indicating that norepinephrine effect is through postsynaptic alpha-2 adrenoceptors. The present data demonstrate that the nature of melanophore innervation in this teleost is adrenergic and neuro-melanophore signals mediating melanosome aggregation are transmitted through alpha-2 postsynaptic adrenoceptors.
Analysis of the Word-Initial Segment with Reference to Lemmatising Zulu Nasal Nouns
M.H. Mpungose
Lexikos , 2012, DOI: 10.5788/8-1-945
Abstract: The process of lemmatising nasal nouns in the Zulu lexicon is problematic. The traditional method is to lemmatise a Zulu lexical noun by etymological noun-stem. This practice creates difficulties in harmonising lexical nouns with their syntactic application. Most authors and dictionary-makers are inconsistent in identifying the word-initial segment which determines the letter of the alphabet under which the lexical noun should be included. Consequently, dictionary users do not find Zulu dictionaries user-friendly. This article therefore proposes the principle of "a noun without initial vowel" as a method for lemmatising Zulu nasal nouns. It concludes that it is not necessary to delve into the derivational history of a lexical noun, but rather to focus on the product of the operation of morphophonological rules. The article also suggests the need to identify the distinctiveness of the segments of a syllable and to acknowledge that identical forms of a segment do occur at different segmental positions (initial, medial and final). Finally it is argued that the Zulu nasal noun class prefix is constructed according to an open syllable pattern defined by a general CV-formula based on a VCV noun prefix open syllable pattern. Keywords: adjoined letter; compound; composite; consonant; element; etymological; evolutionary; homorganic; initial; intravowel; lemma; lemmatise; lexical; morphophonological; nasal; noun class prefix; segment; syllable; vowel Die proses van lemmatisering van nasale naamwoorde in die Zoeloeleksikon is problematies. Die tradisionele metode is om leksikale selfstandige naamwoorde in Zoeloe volgens die etimologiese naamwoordstam te lemmatiseer. Hierdie gebruik veroorsaak moeilikhede by die harmonisering van leksikale selfstandige naamwoorde met hul sintaktiese toepassing. Die meeste outeurs en leksikograwe is inkonsekwent in die identifisering van die woordinisi le segment wat die letter van die alfabet bepaal waaronder die leksikale selfstandige naamwoord geplaas moet word. Gevolglik vind woordeboekgebruikers Zoeloewoordeboeke nie gebruikersvriendelik nie. In hierdie artikel word die beginsel van "'n selfstandige naamwoord sonder inisi le klinker" dus voorgestel as 'n metode om nasale naamwoorde in Zoeloe te lemmatiseer. Daar word tot die gevolgtrekking gekom dat dit nie nodig is om op die afleidingsgeskiedenis van 'n leksikale naamwoord in te gaan nie, maar dat daar eerder gefokus moet word op die produk van die werking van die morfofonologiese re ls. Die artikel gee dit ook ter oorweging dat dit nodig is om die onderskeidende kenm
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