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Search Results: 1 - 10 of 482459 matches for " M. O. Amodu "
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Prevalence and Correlates of Physical Disability and Functional Limitation among Elderly Rural Population in Nigeria
I. S. Abdulraheem,A. R. Oladipo,M. O. Amodu
Journal of Aging Research , 2011, DOI: 10.4061/2011/369894
Abstract: Background. The number of people surviving into old age is increasing, and it has now become a global phenomenon. Studies on the prevalence and correlates of physical disability and functional limitation among elderly Nigerians are scanty. Methodology. This is a community-based cross-sectional study conducted in 3 local government areas (LGAs) in Nigeria, using a multistage sampling technique. Functional limitations of 1824 elderly persons were tested using Tinetti performance-oriented mobility assessment tool (TPOMAT) and self-reported activities of daily living (ADL). ADL disability of ten, six, and five basic items were compared. Results. The prevalence ratios (PRs) of physical disability using the ten, six, and five basic ADL items were 28.3 (95% CI 25.2–31. 5), 15.7 (95% CI 13.4–19.8), and 12.1 (95% CI 9.8–15.3), respectively, while functional limitation was 22.5 (95% CI 18.1–24.4). Increased risk of disability was independently associated with female gender PR 3.6 (95% CI 1.5–7.4), advanced age ≥75 years; PR 22.2 (95% CI 14.5, 36.8), arthritis PR 3.7 (95% CI 2.6–4.6), stroke PR 4.8 (95% CI 3.7–7.9) and diabetes PR 6.1 (95% CI 4.3–7.1). Conclusions. The findings from this study are pointers to unmet needs of the elderly disabled Nigerians. 1. Introduction The number of people surviving into old age is increasing, and it is a global phenomenon affecting developing and developed countries [1]. Information on disability is very important in responding to the care of the elderly. Disability is defined as a restriction in the ability to perform normal activities of daily living [2], and it helps to quantify the impact of disease or injury. Disability is particularly a useful concept in assessing the health of elderly people, because they have several diseases occurring simultaneously with varied severity and impacts on their daily lives. Gill and colleagues [3] have reported the powerful effects of disability on individual well-being, the need for informal help and health care, as well as long-term care needs and costs. On the basis of this, the epidemiology of elderly disability cannot be overemphasized. The process of disability represents a distinct phase in the life of many elderly persons [2]. Functional limitation is associated with loss of independence and with increased need for both formal and informal care [4, 5]. The prevalence of physical disability in elderly persons with functional limitation are, therefore, important for policy development on care of the elderly be it formal or informal care. Contrary to the developed nations [6], most
Knowledge, Attitude and Practice of Skin Whitening among Female University Students in Northeastern Nigeria  [PDF]
M. O. Amodu, M. T. Bolori, I. M. Ahmad, A. Kale, A. Kuchichi
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104501
Introduction: Skin whitening is the act of brightening the skin complexion by using substances that are applied on the skin or administered into the body by other means. The use of skin whitening agents has its drawback in terms of causing harmful effects such as skin disorders like depigmentation, rashes, pimples, discolorations, kidney damaged, cancers, neurological and psychiatric disorders depending on how the agents for skin whitening are used. Objective: The paper examines the knowledge, attitude and practice of skin whitening by university female students in north eastern Nigeria, where some dark skinned women in particular tend to bleach their skin. Method: A cross sectional descriptive study. Results: The awareness level of the students about skin whitening agents and their harmful effects was found to be high among the students and little below, half of them are already users of such agents mainly for beautification. Few of them think the use of skin whitening agents can be addictive and lead to social stigma but they don’t believe that the use of such agents should be restricted to medical only. Conclusion: Majority of the female students in the Universities in north-eastern Nigeria bleach their skin with dangerous chemical agents meant for other reasons mainly to attract the opposite sex despite having high knowledge of the harmful effects. Government is highly recommended to take the necessary steps to curtail such menace.
Female Genital Mutilation in Northeastern Nigeria  [PDF]
M. O. Amodu, M. T. Bolori, A. Kuchichi, Ibrahim Musa Ngoshe, F. L. Bukar
Open Access Library Journal (OALib Journal) , 2019, DOI: 10.4236/oalib.1105827
Introduction: Different forms of cultural practices are being practiced in Nigeria and other parts of the world. Some of such are beneficial while others lead to negative impacts. Female genital mutilation as one type of harmful traditional practices is a form of violence against women. Female Genital Mutilation (FGM), practiced in many parts of the world, also known as female circumcision or female genital cutting (FGC), is the practice in which a female child undergoes a process involving the female external genital organ being removed partially or totally for nonmedical reasons, causing a lot of health and other problems during, shortly after the procedure and later in life. Objective: The objective of the study was to understand knowledge and thoughts of women towards female genital mutilation. Method: A cross sectional descriptive study. Results: Most of the respondents were aware of FGM but not as high as in the southern part of Nigeria. The majority knew the meaning of FGM and thought it as a harmful practice done for various reasons. Conclusion: FGM has negative impacts. It is highly recommended for government to enlighten parents more about menace of FGM through community and school health education.
Assessment of the knowledge, attitude and practice of rural women of northeast Nigeria on risk factors associated with cancer of the Cervix  [PDF]
Babatunji A. Omotara, Shuaibu J. Yahya, Mary O. Amodu, John S. Bimba
Health (Health) , 2013, DOI: 10.4236/health.2013.59186

Cervical cancer is the leading cancer-related cause of death among women in Nigeria. An estimated 70,700 new cases occur each year, representing one quarter of all female cancers in sub Saharan Africa. The magnitude of the problem has been under recognised and under prioritised compared with the competing health priorities of infectious diseases such as HIV/ AIDS, tuberculosis and malaria. Studies in the United States and Nigeria have indicated that the disease has the highest incidence among the lowest socio-economic groups especially residing in rural areas. The peak age for the disease has been shown to be within 35-45 years age group. Knowledge of the risk factors of the disease is deemed important in its early detection and prevention. The objective of this study was to assess the knowledge, attitude and practice of rural women with cancer of the cervix. A cross sectional descriptive study was conducted among 1600 rural women aged 15-55 years (randomly selected from 28 villages) who were interviewed using a structured questionnaire between April and June, 2010. The majority (82.2%) were married before the age of 20 years and 19.3% before 15 years, 40% in polygamous union, 22.6% have had 2 or more sexual partners, 71.3% were primi and grand multiparous, 7.5% have had previous treatment for STIs and 10.1% were on various types of contraceptive. 454 (28.4%) have heard of Ca cervix, 358 (22.4%) knew the location of the cervix. 2.3% had Pap smear test of which 72.6% were within 2 years. The majority (89.9%) will avail themselves for screening.

A Correlation Of Symptomatology With Nasal Smear Eosinophilia In Non-Infectious Chronic Rhinitis Preliminary Report
A D Olusesi, M A Said, E J Amodu
Nigerian Journal of Clinical Practice , 2007,
Abstract: Objective: To correlate subjective and objective clinical features with nasal smear cytology findings in non-infectious chronic rhinitis. Design: An analysis of prospectively collected data of consecutive patients with non-infectious seasonal and perennial rhinosinusitis seen at a tertiary health institution. Methodology: Clinical assessments including Visual Analog Scale (VAS) scoring of presenting symptoms of 45 patients suffering from non-infectious chronic rhinosinusitis are measured. Subjects had a medical questionnaire regarding presence and duration of symptoms, family history of atopy or allergy, occupational exposure to allergens, provocative agents, and medication usages. Subjects had detail Ear, Nose, and Throat assessment, and nasal secretions were analyzed for eosinophils counts and statistically correlated with clinical parameter. Result: A total of 45 patients were recruited. Age range was 13 to 71 years (SD 11.516). 73% (n=33) were females while 27% (n=12) were males. The modal occupation was homemaking (24%, n=11). 38% (n=17) had family history of atopy, while 13% (n=6) had family history of allergy. Symptoms were perennial in 62% (n=28) and seasonal in 38% (n=17). 9% (n=4) of the subjects keep pets at home, while 40% (n=18) grow flowers or trees around the house. All subjects gave a history of identifiable provocative agents. There is positive correlation of itchy nose with total symptom score. There was negative history of occupational exposure to allergens in all subjects. The average subjective symptom score are Sneezing (6.3), Itchy nose (6.1), Nasal obstruction (6.2) and Runny nose (6.7). There is a high positive correlation of sneezing with runny nose (r = 0.51), but poor correlation with nasal obstruction (r = 0.15). There is negative correlation of total individual symptom score with keeping of pets (r = -0.24) or growing of flowers or trees around house (r = -0.039). There is also low correlation of total symptom score with family history of atopy (r = 0.06). There is positive correlation of total symptom score with number of provocative agents identified (r = 0.34). There is low positive correlation of nasal smear eosinophilia with total symptom score (r = 0.030) and itchy nose score (r = 0.038). Nasal smear eosinophilia show negative correlation with sneezing score (r = -0.076). Conclusion: The best predictors of nasal smear eosinophilia in non-infectious chronic rhinosinusitis are itchy nose score and Individual Total Symptom (ITS) score.
The Effect of Stocklength, Stock Diameter and Planting Angle on Early Establisment of Gliricidia sepium
J.T. Amodu,O.S. Onifade,I.A. Adeyinka,J.O. Jegede
Pakistan Journal of Biological Sciences , 2007,
Abstract: Legume tree crops, which establish easily and do not require extensive agronomic inputs, constitute potentially valuable sources of supplementary feeds that subsistence and medium-scale livestock farmers in the tropics could use to improve livestock nutrition and productivity. A field trial was conducted with Gliricidia sepium cuttings to investigate the effect if three stock lengths (20, 30 and 40 cm), two stock diameters (1.5-2.5) and (3.0-3.5 cm) and three planting angles (30° , 60° and 90°) in a factorial experiment. There were high significant differences (p<0.05) in all the growth parameters of the stock diameters and stock lengths used. The highest dry matter yield of 3.83, 4.61 and 4.65 t ha-1 were produced by stock length 20, 30 and 40 cm, respectively. The highest planting angle of 90° produced the tallest shoot height and biggest basal diameter, while the least planting angle of 30° produced the least shoot height and basal diameter, respectively. The interactions between the smaller stock diameter and the least planting angle (30° ) produced the least values of growth parameters. Gliricidia cuttings could be easily established with thicker stock diameter of not less than 3.0 and 40 cm stock length, planting in an angle between 60 and 90 degrees.
Early home treatment of childhood fevers with ineffective antimalarials is deleterious in the outcome of severe malaria
Adebola E Orimadegun, Olukemi K Amodu, Peter E Olumese, Olayemi O Omotade
Malaria Journal , 2008, DOI: 10.1186/1475-2875-7-143
Abstract: Two hundred and sixty-eight children with a median age of 30 months comprising 114 children with cerebral malaria and 154 with severe malarial anaemia (as defined by WHO) were prospectively enrolled. Data on socio-demographic data, treatments given at home, clinical course and outcome of admission were collected and analysed.A total of 168 children had treatment with an antimalarial treatment at home before presenting at the hospital when there was no improvement. There were no significant differences in the haematocrit levels, parasite counts and nutritional status of the pre-hospital treated and untreated groups. The most commonly used antimalarial medicine was chloroquine. Treatment policy was revised to Artemesinin-based Combination Therapy (ACT) in 2005 as a response to unacceptable levels of therapeutic failures with chloroquine, however chloroquine use remains high. The risk of presenting as cerebral malaria was 1.63 times higher with pre-hospital use of chloroquine for treatment of malaria, with a four-fold increase in the risk of mortality. Controlling for other confounding factors including age and clinical severity, pre-hospital treatment with chloroquine was an independent predictor of mortality.This study showed that, home treatment with chloroquine significantly impacts on the outcome of severe malaria. This finding underscores the need for wide-scale monitoring to withdraw chloroquine from circulation in Nigeria and efforts intensified at promoting prompt treatment with effective medicines in the community.Malaria remains a significant cause of morbidity and mortality among children and creates enormous social, economic and disease burdens in endemic regions[1,2]. Current control efforts focus on reducing malaria-attributable morbidity and mortality. Prompt evaluation of all febrile illness, case-recognition and use of appropriate antimalarial therapy are essential to malarial control in order to optimize clinical outcomes of malaria-infected patients
An Assessment of the Major Elemental Composition and Concentration in Limestones Samples from Yandev and Odukpani Areas of Nigeria Using Nuclear Techniques
I.O. Akpan,A.E. Amodu,A.E. Akpan
Journal of Environmental Science and Technology , 2011,
Abstract: These observations suggest that all particulate emissions and wastes from the Yandev deposit should be closely monitored to reduce its effects on the environment and health. The average Ca/Si ratio of the Yandev deposit is 4.32 while that of Odukpani deposit is 8.64. The observed low Ca/Si ratio in Yandev Limestone was attributed to the comparatively high Si content of the limestones. Thus the Odukpani limestone deposit appears to be more friendly to health and the environment.
Evaluation of Pearl Millet Accessions for Yield and Nutrient Composition
J.T. Amodu,I.A. Adeyinka,M.S. Kallah,J.P. Alawa
Journal of Biological Sciences , 2007,
Abstract: An experiment was carried out in 2001 and 2002 at the Forage and Crop Residue Research Programme of the National Animal Production Research, Institute, Shika, Nigeria, to evaluate the yield components and nutrient composition of three accessions of pearl millet (Mokwa, Bunkure and Kankara). The three accessions were planted in completely randomized block design in three replications. Sowing was carried out in both years of the trial at the rate of 4 kg seeds per hectare on 10x7.5 m plot. Parameters assessed included plant height, number of tillers/culm, percentage green, leaf:stem ratio, fodder yield (fresh and dry weights). CP, CF, EE, NFE, ash, P, Ca and Mg. Results showed that at 116 post-planting, there were varietal differences in height, tillering ability, leafiness and greenness, which were found significant (p<0.05). The Bunkure accession which was taller, greener and higher in number of tillers had the highest fodder yield of 9.07 and 7.32 t ha-1 of fresh weight and dry weight, respectively. In the three accessions there were no significant differences (p>0.05) in the leaf:stem ratio. Differences between accessions in terms of EE, NFE and P were not significantly different (p>0.05) while significant differences were noticed in ash, CP, CF and Mg content of the millet accessions.
Heme Mediated STAT3 Activation in Severe Malaria
Mingli Liu, Audu S. Amodu, Sidney Pitts, John Patrickson, Jacqueline M. Hibbert, Monica Battle, Solomon F. Ofori-Acquah, Jonathan K. Stiles
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0034280
Abstract: Background The mortality of severe malaria [cerebral malaria (CM), severe malaria anemia (SMA), acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)] remains high despite the availability associated with adequate treatments. Recent studies in our laboratory and others have revealed a hitherto unknown correlation between chemokine CXCL10/CXCR3, Heme/HO-1 and STAT3 and cerebral malaria severity and mortality. Although Heme/HO-1 and CXCL10/CXCR3 interactions are directly involved in the pathogenesis of CM and fatal disease, the mechanism dictating how Heme/HO-1 and CXCL10/CXCR3 are expressed and regulated under these conditions is still unknown. We therefore tested the hypothesis that these factors share common signaling pathways and may be mutually regulated. Methods We first clarified the roles of Heme/HO-1, CXCL10/CXCR3 and STAT3 in CM pathogenesis utilizing a well established experimental cerebral malaria mouse (ECM, P. berghei ANKA) model. Then, we further determined the mechanisms how STAT3 regulates HO-1 and CXCL10 as well as mutual regulation among them in CRL-2581, a murine endothelial cell line. Results The results demonstrate that (1) STAT3 is activated by P. berghei ANKA (PBA) infection in vivo and Heme in vitro. (2) Heme up-regulates HO-1 and CXCL10 production through STAT3 pathway, and regulates CXCL10 at the transcriptional level in vitro. (3) HO-1 transcription is positively regulated by CXCL10. (4) HO-1 regulates STAT3 signaling. Conclusion Our data indicate that Heme/HO-1, CXCL10/CXCR3 and STAT3 molecules as well as related signaling pathways play very important roles in the pathogenesis of severe malaria. We conclude that these factors are mutually regulated and provide new opportunities to develop potential novel therapeutic targets that could be used to supplement traditional prophylactics and treatments for malaria and improve clinical outcomes while reducing malaria mortality. Our ultimate goal is to develop novel therapies targeting Heme or CXCL10-related biological signaling molecules associated with development of fatal malaria.
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