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Search Results: 1 - 10 of 402539 matches for " M. Milagro Montero "
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Prevalence and Factors Associated with Vitamin D Deficiency and Hyperparathyroidism in HIV-Infected Patients Treated in Barcelona
Elisabet Lerma,M. Ema Molas,M. Milagro Montero,Ana Guelar
ISRN AIDS , 2012, DOI: 10.5402/2012/485307
Prevalence and Factors Associated with Vitamin D Deficiency and Hyperparathyroidism in HIV-Infected Patients Treated in Barcelona
Elisabet Lerma,M. Ema Molas,M. Milagro Montero,Ana Guelar,Alicia González,Judith Villar,Adolf Diez,Hernando Knobel
ISRN AIDS , 2012, DOI: 10.5402/2012/485307
Abstract: Vitamin D deficiency is an important problem in patients with chronic conditions including those with human immunodeficiency virus (HIV) infection. The aim of this cross-sectional study was to identify the prevalence and factors associated with vitamin D deficiency and hyperparathyroidism in HIV patients attended in Barcelona. Cholecalciferol (25OH vitamin D3) and PTH levels were measured. Vitamin D insufficiency was defined as 25(OH) D < 20?ng/mL and deficiency as <12?ng/mL. Hyperparathyroidism was defined as PTH levels >65?pg/mL. Cases with chronic kidney failure, liver disease, treatments or conditions potentially affecting bone metabolism were excluded. Among the 566 patients included, 56.4% were exposed to tenofovir. Vitamin D insufficiency was found in 71.2% and 39.6% of those had deficiency. PTH was measured in 228 subjects, and 86 of them (37.7%) showed high levels. Adjusted predictors of vitamin D deficiency were nonwhite race and psychiatric comorbidity, while lipoatrophy was a protective factor. Independent risk factors of hyperparathyroidism were vitamin D < 12?ng/mL (OR: 2.14, CI 95%: 1.19–3.82, P: 0.01) and tenofovir exposure (OR: 3.55, CI 95%: 1.62–7.7, P: 0.002). High prevalence of vitamin deficiency and hyperparathyroidism was found in an area with high annual solar exposure. 1. Introduction Vitamin D is a steroid liposoluble hormone and can be made available to the individuals in two forms. First, vitamin D3 or cholecalciferol is synthesized in the skin in response to ultraviolet B radiation and is present in oil-rich fish (salmon, mackerel, and herring), egg yolks, and liver [1]. Second, vitamin D2 or ergocalciferol is obtained from the UV irradiation of the yeast sterol ergosterol and is found in sun-exposed mushrooms [2]. Both vitamins undergo identical metabolism, and as they are biologically inert, they require two hydroxylations, in the liver and in the kidney, to become 1,25dihydroxyvitamin D [1,25(OH)2D] which is the biologically active form of the hormone [3, 4]. In the intestine this stimulates the absorption of calcium and phosphorus, and it helps to regulate the metabolism of both minerals within bone and kidney interaction [5]. Assessment of vitamin D is based on measurement of serum 25(OH)D [6, 7] that is the most stable and plentiful metabolite of vitamin D in serum and has a half-life about 21 days [8]. The main source of vitamin D is exposure to sunlight [9, 10]. Therefore, an insufficient exposure to sunlight is a major cause of vitamin D deficiency. Other causes of vitamin deficiency are sunscreen sun protection [2],
Status of the Milagro Gamma Ray Observatory
The Milagro Collaboration
Physics , 2001,
Abstract: The Milagro Gamma Ray Observatory, located at an altitude of 8,600 feet in the Jemez Mountains of New Mexico, is the world's first large-area water Cherenkov detector capable of continuously monitoring the entire sky for sources of TeV gamma rays. It is uniquely capable of searching for transient sources of VHE gamma rays. The core of the detector is a 60m x 80m x 8m pond instrumented with 723 PMTs deployed in two layers. This part of the detector is complete and has operated continuously since Jan. 2000. Initial studies including searches for gamma-ray sources are ongoing, and preliminary results are available. The final stage of construction is under way. We are deploying 170 auxiliary "outrigger" water Cherenkov detectors in an area of 40,000 square-meters surrounding the pond, which will significantly enhance our ability to reject background and more accurately reconstruct the gamma-ray direction and energy. In addition, we are lowering the energy threshold of the detector by using custom processing to enable real-time intelligent triggering. The lower energy threshold will significantly increase our sensitivity to gamma-ray sources, and in particular to sources of cosmological origin, such as GRBs, where the higher energy gamma-rays have sizable attenuation due to the interaction with the intergalactic infra-red light.
Observation of TeV Gamma Rays from the Crab Nebula with Milagro Using a New Background Rejection Technique
The Milagro Collaboration
Physics , 2003, DOI: 10.1086/377498
Abstract: The recent advances in TeV gamma-ray astronomy are largely the result of the ability to differentiate between extensive air showers generated by gamma rays and hadronic cosmic rays. Air Cherenkov telescopes have developed and perfected the "imaging" technique over the past several decades. However until now no background rejection method has been successfully used in an air shower array to detect a source of TeV gamma rays. We report on a method to differentiate hadronic air showers from electromagnetic air showers in the Milagro gamma ray observatory, based on the ability to detect the energetic particles in an extensive air shower. The technique is used to detect TeV emission from the Crab nebula. The flux from the Crab is estimated to be 2.68(+-0.42stat +- 1.4sys) x10^{-7} (E/1TeV)^{-2.59} m^{-2} s^{-1} TeV^{-1}, where the spectral index is assumed to be as given by the HEGRA collaboration.
La castellanización de Li Livres dou Tresor de Brunetto Latini en la corte de Sancho IV (1284-1295): algunas notas sobre la recepción de la ética aristotélica
Montero, Ana M.
Anuario de Estudios Medievales , 2010,
Abstract: This article focuses on the translation into Castilian of Brunetto Latini’s Li Livres dou tresor. This translation was ordered by king Sancho IV around 1293, and included the first extant abridged version of Aristotle’s Nicomachean Ethics (Summa Alexandrinorum) in Castilian. Nevertheless, the Aristotelian ethics would not become popular until the fifteenth century. This article aims at qualifying the initial reception of Libro del tesoro. Therefore, the interpolations of short explanations in the translation to Castilian are analyzed. It is observed that the effort to clarify the meaning of some concepts is evident in the chapters on ethics and does impinge on the Aristotelian notion of happiness or eudaimonia. Este trabajo se centra en la traducción al castellano de la obra de Brunetto Latini, Li Livres dou tresor. Dicha traducción —requerida por el rey castellano Sancho IV en torno a 1293— permitió la aparición de la primera versión abreviada, en castellano, de la ética a Nicómaco de Aristóteles (Summa Alexandrinorum); sorprendentemente la ética aristotélica no alcanzaría popularidad hasta el siglo XV. Este trabajo trata de ahondar en el tipo de recepción inicial que tuvo el Libro del tesoro, para lo cual se analizan las interpolaciones de breves explicaciones en la traducción al castellano. Se observa que el esfuerzo por aclarar el sentido de algunos conceptos se da mayoritariamente en la parte de la ética a Nicómaco y afecta en particular a la noción de eudaimonía.
Algunos ejemplos aislados de la presencia de pintura barroca espa ola y flamenca en Galicia
Monterroso Montero, Juan M.
Cuadernos de Estudios Gallegos , 1996,
Abstract: Not avalaible No disponible
La condición social del pintor en la Galicia de los siglos XVII y XVIII
Monterroso Montero, Juan M.
Cuadernos de Estudios Gallegos , 1995,
Abstract: Not available. No disponible.
Hospital costs of nosocomial multi-drug resistant Pseudomonas aeruginosa acquisition
Eva Morales, Francesc Cots, Maria Sala, Mercè Comas, Francesc Belvis, Marta Riu, Margarita Salvadó, Santiago Grau, Juan P Horcajada, Maria Milagro Montero, Xavier Castells
BMC Health Services Research , 2012, DOI: 10.1186/1472-6963-12-122
Abstract: A retrospective study of all hospital admissions between January 1, 2005, and December 31, 2006 was carried out in a 420-bed, urban, tertiary-care teaching hospital in Barcelona (Spain). All patients with a first positive clinical culture for P. aeruginosa more than 48 h after admission were included. Patient and hospitalization characteristics were collected from hospital and microbiology laboratory computerized records. According to antibiotic susceptibility, isolates were classified as non-resistant, resistant and multi-drug resistant. Cost estimation was based on a full-costing cost accounting system and on the criteria of clinical Activity-Based Costing methods. Multivariate analyses were performed using generalized linear models of log-transformed costs.Cost estimations were available for 402 nosocomial incident P. aeruginosa positive cultures. Their distribution by antibiotic susceptibility pattern was 37.1% non-resistant, 29.6% resistant and 33.3% multi-drug resistant. The total mean economic cost per admission of patients with multi-drug resistant P. aeruginosa strains was higher than that for non-resistant strains (15,265 vs. 4,933 Euros). In multivariate analysis, resistant and multi-drug resistant strains were independently predictive of an increased hospital total cost in compared with non-resistant strains (the incremental increase in total hospital cost was more than 1.37-fold and 1.77-fold that for non-resistant strains, respectively).P. aeruginosa multi-drug resistance independently predicted higher hospital costs with a more than 70% increase per admission compared with non-resistant strains. Prevention of the nosocomial emergence and spread of antimicrobial resistant microorganisms is essential to limit the strong economic impact.
Estimation of the TeV gamma-ray duty cycle of Mrk 421 with the Milagro observatory
B. Patricelli,M. M. González,N. Fraija,A. Marinelli,for the Milagro collaboration
Physics , 2014, DOI: 10.1016/j.nima.2013.11.044
Abstract: Markarian 421 (Mrk 421) is one the brightest and closest (z=0.031) blazars known (de Vaucouleurs et al 1991). It is also one of the fastest varying TeV $\gamma$-ray sources, with a flaring activity on time scales as short as tens of minutes. The activity of Mrk 421 at different frequencies may reflect the radiation mechanisms involved. Tluczykont et al. (2007) estimated the TeV activity of Mrk 421 through calculating the fraction of time spent in flaring states at TeV energies (TeV duty cycle) by using data from several imaging atmospheric Cherenkov telescopes (IACTs). Since IACT observations are biased towards high flux states they overestimated the TeV duty cycle of Mrk 421. Here we propose an alternative approach to calculate the TeV duty cycle of Mrk 421 that takes advantage of the continuous monitoring of the source by the Milagro experiment, a water Cherenkov detector sensitive to primary $\gamma$-rays between 100 GeV and 100 TeV. We present our estimation of the TeV - duty cycle and study its robustness.
Study of TeV variability of Mrk 421 from 3 years of monitoring with the Milagro Observatory
B. Patricelli,M. M. González,N. Fraija,A. Marinelli,for the Milagro collaboration
Physics , 2014, DOI: 10.1142/9789814623995_0072
Abstract: The Milagro experiment was a TeV gamma-ray observatory designed to continuously monitor the overhead sky in the 0.1-100 TeV energy range. It operated from 2000 and 2008 and was characterized by a large field of view ($\sim$ 2 sr) and a high duty cycle ($\geq$ 90$\%$). Here we report on the long-term monitoring of the blazar Mrk 421 with Milagro over the period from September 21, 2005 to March 15, 2008. We present a study of the TeV variability of the source and provide upper limits for the measured flux for different time scales, ranging from one week up to one year.
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