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Search Results: 1 - 10 of 407111 matches for " M. Gupta "
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Sero-Prevalence of Paratuberculosis (Johne's Disease) in Cattle Population of South-Western Bangalore Using ELISA Kit  [PDF]
Anvita Gupta, Sobha M. Rani, Pushpa Agrawal, Praveen Kumar Gupta
Open Journal of Veterinary Medicine (OJVM) , 2012, DOI: 10.4236/ojvm.2012.24031
Abstract: Johne's disease or paratuberculosis is a chronic mycobacterial infection that affects cattle, sheep, goats and other ruminants, adversely, leading to huge economic losses throughout the world. The estimation of sero-prevalence of this disease in the cattle population of south-western Bangalore, Karnataka, using an immunological assay and statistical analyses, was the objective of this study. One of the diagnostic tools used to detect an antigen or an antibody in animal serum or milk is the Enzyme Linked Immuno-Sorbent Assay, which has been widely used in the research and diagnosis of animal and human diseases as its accuracy is of nanogram-picogram/milliltre level. In the present study, indirect-ELISA was used to diagnose and estimate the sero-prevalence of paratuberculosis in cattle showing diarrhoea and/or anaemia, at 5 local dairy farms in south-west Bangalore, India. Out of 350 bovine serum samples, 53 (15.14%) were positive, 55 milk samples out of 300 were found positive (18.33%) for antibody against Johne's disease by indirect ELISA. The positive samples were then confirmed by direct smear examination of dung by Ziehl-Neelsen staining. Statistical analyses were carried out to indicate the seroprevalence of Johne's disease in the cattle population of this region to be 15 ± 10%, taking a confidence interval of 95%. The results emphasize the need to prevent the further spread of infection to other susceptible animals and humans as the causative organism, Mycobacterium avium subsp. paratuberculosis is implicated in Crohn's disease, an irritable bowel syndrome in humans.
Significance of antiphospholipid antibodies in patients with bad obstetric history
Mishra M,Gupta Sapna,Gupta M
Indian Journal of Medical Sciences , 2007,
Subretinal neovascularization associated with retinochoroidal coloboma
Gupta Vishali,Gupta Amod,Dogra M
Indian Journal of Ophthalmology , 1997,
Low-Voltage MOS Current Mode Logic Multiplexer
K. Gupta,N. Pandey,M. Gupta
Radioengineering , 2013,
Abstract: In this paper, a new low-voltage MOS current mode logic (MCML) multiplexer based on the triple-tail cell concept is proposed. An analytical model for static parameters is formulated and is applied to develop a design approach for the proposed low-voltage MCML multiplexer. The delay of the proposed low-voltage MCML multiplexer is expressed in terms of the bias current and the voltage swing so that it can be traded off with the power consumption. The proposed low-voltage MCML multiplexer is analyzed for the three design cases namely high-speed, power-efficient, and low-power. Finally, a comparison in performance of the proposed low-voltage MCML multiplexer with the traditional MCML multiplexer is carried out for all the cases.
Surgical treatment and histopathological analysis of proptosis
SAR Rizvi,Y Gupta,M Gupta
Nepalese Journal of Ophthalmology , 2010, DOI: 10.3126/nepjoph.v2i1.3701
Abstract: Introduction: Inflammations and tumors of the orbit and para-orbital regions may present as proptosis. Management depends on clinical, radiological, histo-pathological and biochemical evaluation. Objective : To analyze the clinical and histopathological profile of the lesions causing proptosis and to report the outcome of their surgical management. Materials and methods: In a retrospective study, 25 cases of proptosis due to orbital and paraorbital tumours were analyzed in relation to their age, sex, and clinical and histopathological profiles. CT Scan was considered as the first line investigation modality. According to location and type of tumour, different surgical options like anterior orbitotomy, lateral orbitotomy and medial orbitotomy were considered. Results: The majority of the patients were of the age group 50-59 years (28 %). Primary orbital tumors were encountered in 15 cases (60 %) and para-orbital in 10 (40 %). Of 15 primary orbital tumors, 7 (46.66 %) were excised by lateral orbitotomy, another 7 (46.66 %) were approached via anterior orbitotomy, whereas 1 (6.67%) was removed by medial orbitotomy. Pediatric orbital tumors were quite common {7(46.66%)}. Three cases of rhabdomyosarcoma, 3 cases of dermoid cyst and 1 case each of optic nerve glioma were found in pediatric age group. The most common benign adult tumor found in our study was pleomorphic adenoma of the lacrimal gland {3(20%)}. Conclusion : The majority of the patients with proptosis are of the age group 50-59 years. Proptosis due to primary orbital tumors is more common than para-orbital tumors. Early diagnosis and timely surgical intervention provide good functional and cosmetic results. Keywords : orbit; proptosis; tumors; orbitotomy. DOI: 10.3126/nepjoph.v2i1.3701 Nep J Oph 2010;2(1):31-34
Physiological disproportions between un-corrected vision and degree of myopia
Y Gupta,SAR Rizvi,M Gupta
Nepalese Journal of Ophthalmology , 2010, DOI: 10.3126/nepjoph.v2i2.3721
Abstract: Introduction: Anomalies of the refractive state of the eye are the commonest cause of defective vision.
Magnetism and Electronic Structure in ZnFe$_2$O$_4$ and MnFe$_2$O$_4$
D. J. Singh,M. Gupta,R. Gupta
Physics , 2001, DOI: 10.1063/1.1453929
Abstract: Density functional calculations are used to study magnetic and electronic properties of the spinel ferrites, ZnFe$_2$O$_4$ and MnFe$_2$O$_4$. Correct magnetic orderings are obtained. ZnFe$_2$O$_4$ is predicted to be a small gap insulator in agreement with experiment. MnFe$_2$O$_4$ is found to be a low carrier density half-metal in the fully ordered state. However, strong effects on the electronic structure are found upon partial interchange of Fe and Mn atoms. This indicates that the insulating character may be due to Anderson localization associated with the intersite Mn-Fe disorder.
Modified Grover's search algorithm for the cases where the number of solutions is known
A. S. Gupta,M. Gupta,A. Pathak
Physics , 2005,
Abstract: Grover's search algorithm searches a database of $N$ unsorted items in $O(\sqrt{N/M})$ steps where $M$ represents the number of solutions to the search problem. This paper proposes a scheme for searching a database of $N$ unsorted items in $O(logN)$ steps, provided the value of $M$ is known. It is also shown that when $M$ is unknown but if we can estimate an upper bound of possible values of $M$, then an improvement in the time complexity of conventional Grover's algorithm is possible. In that case, the present scheme reduces the time complexity to $O(MlogN)$.
Cohesion of BaReH$_9$ and BaMnH$_9$: Density Functional Calculations and Prediction of (MnH$_9)^{2-}$ Salts
D. J. Singh,M. Gupta,R. Gupta
Physics , 2006, DOI: 10.1103/PhysRevB.75.035103
Abstract: Density functional calculations are used to calculate the structural and electronic properties of BaReH$_9$ and to analyze the bonding in this compound. The high coordination in BaReH$_9$ is due to bonding between Re 5$d$ states and states of $d$-like symmetry formed from combinations of H $s$ orbitals in the H$_9$ cage. This explains the structure of the material, its short bond lengths and other physical properties, such as the high band gap. We compare with results for hypothetical BaMnH$_9$, which we find to have similar bonding and cohesion to the Re compound. This suggests that it may be possible to synthesize (MnH$_9)^{2-}$ salts. Depending on the particular cation, such salts may have exceptionally high hydrogen contents, in excess of 10 weight %
Protein Based Drug Discovery
Joshi B.,Gupta G.,Gupta N.,Gupta M.
International Journal of Drug Discovery , 2009,
Abstract: New drug target discovery is currently very popular with a great potential for advancingbiomedical research and chemical genomics. Drug discovery is the process of discovering and designingdrugs that includes target identification, target validation, lead identification, lead optimization andintroduction of the new drugs to the public. G protein-coupled receptors are one of the most important drugtargets. In the current scenario of drug research, approximately 60% of drug target molecules are located atthe cell surface, and half of them are GPCRs. Fragment-based drug discovery is established as analternative approach to high-throughput screening for generating novel small molecule drug candidates.Nanotechnology-based drug delivery systems have seen recent popularity due to their favorable physical,chemical, and biological properties, and great efforts have been made to target nanoDDSs to specificcellular receptors. Protein-protein interactions regulate a wide variety of important cellular pathways, andtherefore represent a highly populated class of targets for drug discovery. An analysis of individual proteinproteininteraction systems has recently yielded success in the discovery of drug-like inhibitors.
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