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Search Results: 1 - 10 of 559898 matches for " M. C. Rakesh Kumar "
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Screening of selected biological activities of Artocarpus lakoocha Roxb (Moraceae) fruit pericarp
M. B. Shailendra Kumar,M. C. Rakesh Kumar,A. C. Bharath,H. R. Vinod Kumar
Journal of Basic and Clinical Pharmacy , 2010,
Abstract: Artocarpus lakoocha Roxb (Moraceae) is cultivated in Uttar Pradesh, Bengal, Khasi Hills and Western Ghats. Objectives of the present study were to determine antibacterial, antioxidant, anthelmintic and insecticidal efficacy of methanol extract of A. lakoocha fruit pericarp. Antibacterial activity was tested against by Agar well diffusion method. Antioxidant activity in terms of free radical scavenging ability was determined by DPPH free radical scavenging assay. Anthelmintic efficacy was determined using adult Indian earthworm. Insecticidal activity was tested against second and third instar larvae of Aedes aegypti. The extract has shown dose dependent antibacterial, antioxidant, anthelmintic and insecticidal activity. Among bacteria, S. aureus has shown more susceptibility than K. pneumoniae and P. aeruginosa. The extract exhibited marked antioxidant activity by scavenging DPPH free radical. The IC50 value for extract was found to be 49.42μg/ml. The extract exhibited marked anthelmintic activity by causing paralysis and death of worms and the effect was found to be dose dependent. The extract concentration 100mg/ml has shown marked anthelmintic effect than standard drug. In insecticidal study, the 2nd instar larvae were shown to be more susceptible than 3rd instar larvae. Phytochemical analysis revealed the presence of tannins and alkaloids. The presence of these phytoconstituents might be responsible for the biological activities of extract tested. The extract could be used to treat free radical damage, bacterial and helmintic infections and to control insect vectors. Further studies on isolation of constituents and their bio-efficacies in vitro and in vivo are under investigation.
EFFICACY OF LEECH THERAPY AND AYURVEDIC COMPOUND IN VITILIGO: A QUASI EXPERIMENTAL STUDY
Panigrahi Hemanta kumar,Rana Rakesh Kumar,Rao M.M.
International Journal of Research in Ayurveda and Pharmacy , 2012,
Abstract: This interventional, quasi-experimental study (pre-post test design) was conducted at Ayurveda Central Research Institute, New Delhi to study the efficacy of Leech Therapy along with some Ayurvedic medicine in vitiligo. Patients were selected by non-probability purposive sampling method after obtaining an informed consent. Twenty patients suffering from vitiligo (12 male and 08 female), aged more than 15 years and involving less than 25% of body surface area were enrolled. All the patients were kept in a single group. All the patients were called to OPD for Leech application once in a week. The patients were followed up weekly for first month and later on fortnightly for five months to monitor the improvement and adverse effects. The mean re-pigmentation achieved was 60 % (VASI score of 3.69), while the arrest of progression (stationary) was noted in 35 % of patients. In 5% of patient it was spreading. We recommend that leech therapy along with internal administration of Ayurvedic medicine is effective in the treatment of Vitiligo.
Effect of shear force on the separation of double stranded DNA
Rakesh Kumar Mishra,Garima Mishra,M. S. Li,Sanjay Kumar
Physics , 2011, DOI: 10.1103/PhysRevE.84.032903
Abstract: Using the Langevin Dynamics simulation, we have studied the effects of the shear force on the rupture of short double stranded DNA at different temperatures. We show that the rupture force increases linearly with the chain length and approaches to the asymptotic value in accordance with the experiment. The qualitative nature of these curves almost remains same for different temperatures but with a shift in the force. We observe three different regimes in the extension of covalent bonds (back bone) under the shear force.
Artificial Neural Networks for Event Based Rainfall-Runoff Modeling  [PDF]
Archana Sarkar, Rakesh Kumar
Journal of Water Resource and Protection (JWARP) , 2012, DOI: 10.4236/jwarp.2012.410105
Abstract: The Artificial Neural Network (ANN) approach has been successfully used in many hydrological studies especially the rainfall-runoff modeling using continuous data. The present study examines its applicability to model the event-based rainfall-runoff process. A case study has been done for Ajay river basin to develop event-based rainfall-runoff model for the basin to simulate the hourly runoff at Sarath gauging site. The results demonstrate that ANN models are able to provide a good representation of an event-based rainfall-runoff process. The two important parameters, when predicting a flood hydrograph, are the magnitude of the peak discharge and the time to peak discharge. The developed ANN models have been able to predict this information with great accuracy. This shows that ANNs can be very efficient in modeling an event-based rainfall-runoff process for determining the peak discharge and time to the peak discharge very accurately. This is important in water resources design and management applications, where peak discharge and time to peak discharge are important input variables
KSHARASUTRA THERAPY - A MINIMAL INVASIVE PARASURGICAL METHOD IN THE TREATMENT OF SACROCOCCYGEAL PILONIDAL SINUS (NADI VRANA): RESULT OF A PILOT STUDY
Panigrahi Hemanta,Rana Rakesh Kumar,Rao M.M.
International Journal of Research in Ayurveda and Pharmacy , 2012,
Abstract: Many treatment methods have been applied in the treatment of Sacrococcygeal Pilonidal Sinus (Nadi vrana) disease (PSD).Our observations demonstrated Efficacy of Ksharasutra therapy –A minimal invasive Para surgical method in Sacrococcygeal Pilonidal Sinus (Nadi vrana) Disease (Nadi vrana). 20 patients were treated (3 women, 17 men) with PSD by Ksharasutra therapy. All patients were treated on an outpatient basis in the minor Ksharasutra operation theater in ACRI, New Delhi. The mean age was 27 years (18–60). The median length of symptoms was seven months. In the 1 year of mean follow-up period, the disease recurred in 2 patients. This treatment procedure was well-tolerated by all the patients. Time off work was on average one day with an MSD1.75 and SD 0.766485. No patient had skin necrosis or any other complications during the therapy. Recurrence of the disease in two patients was found. Mean Time required for wound healing in week was 10.8 with SD 2.501999. 1(5%) patient had wound infection. It is possible to treat patients in a shorter time with a considerably smaller loss of working time, since the destruction of peripilonidal adipose tissue and skin is less and reoccurrence of the disease is also less, therefore, the use of Ksharasutra therapy in Sacrococcygeal Pilonidal Sinus (Nadi vrana) is an option to be considered in the treatment of PSD.
Facility Location Selection: An Interval Valued Intuitionistic Fuzzy TOPSIS Approach
Ajay Kumar Verma,Rakesh Verma,N.C. Mahanti
Journal of Modern Mathematics and Statistics , 2012, DOI: 10.3923/jmmstat.2010.68.72
Abstract: The aim of this study is to select the best location for multi-criteria decision making facility location with interval valued intuitionistic fuzzy information in which the information about attribute weights is completely known and the attribute values take the form of interval valued intuitionistic fuzzy numbers. The weighted Euclidean distances between every facility location alternative with positive ideal solution and negative ideal solution are calculated. Then according to the weighted Euclidean distances, the relative closeness degree to the positive ideal solution is calculated to rank all location alternatives. Finally, an illustrative example about facility location selection is considered to verify the developed approach.
A Novel Four Layer Metallization for Microwave Integrated Circuits
Rakesh Kumar Sharma;Sandeep Patel;Arun Bindal;Kamlesh C. Pargaien
PIER Letters , 2012, DOI: 10.2528/PIERL11120607
Abstract: In order to overcome the problems facing Cr-Cu-Au metallization, such as discoloration, diffusion of Cu into Au, a four-layer metallization Cr-Cu-NiP-Au is demonstrated on alumina substrate for microwave integrated circuit (MICs). A amorphous and nonmagnetic NiP barrier layer is used to avoid the diffusion of Cu into Au through the grain boundaries, which are the low activation energy path for diffusion at moderate temperature. In this view, properties of Cr-Cu-NiP-Au metallization, such as sheet resistance, solderability, bondability and adhesion strength, are evaluated. Further integrity of Cr-Cu-NiP-Au structure is evaluated by subjecting to this structure to multiple temperature cycles test. Visual observation is carried our before and after the thermal cycling test. No degradation is observed as the consequence of thermal cycling test. Test and evaluation are carried out for a multi-section broadband power divider (1 : 2) on this metallization (metal thickness 12-12.5 microns) in the 0-6 GHz frequency range. Insertion loss, return loss and isolation are comparable with Cr-Cu-Au (metal thickness 5.0-6.0 microns). Performance of the power divider and properties of this metallization system reveal its novelty over the existing.
Effect of Amorphous, Nonmagnetic Barrier Layer on the Performance of a Multisection Wilkinson Broadband Power Divider
Rakesh Kumar Sharma;Sandeep Patel;Arun Bindal;Kamlesh C. Pargaien
PIER Letters , 2012, DOI: 10.2528/PIERL12021107
Abstract: A four-layer metallization Cr-Cu-NiP-Au with amorphous and nonmagnetic NiP as a barrier layer is one of the promising candidates for use in microwave integrated circuits. Multi-section Wilkinson broadband 1:2 power divider circuits are delineated photolithographically on alumina substrates metallized by Cr, TiW, Ni, NiP, copper and gold using different metallization processes. The adhesion and dc resistivity are compared for different metallization scheme. Testing and evaluation have been carried out for multi-section Wilkinson broadband 1:2 power divider in the 10 MHz-6 GHz frequency range for Cr-Cu-Au, TiW-Ni-Au and Cr-Cu-NiP-Au to see the effect of NiP. Insertion loss, return loss and isolation are measured and compared. The microwave properties do not show any appreciable differences due to the various metallizations.
Surgical management of intracranial aneurysms previously treated with endovascular therapy
Kumar Rajiv,Deopujari C,Shah Rajan,Luhana Rakesh
Neurology India , 2010,
Abstract: Endovascular treatment with coils of cerebral aneurysm is being increasingly used for definitive treatment. An increasing number of patients are coming for surgical intervention either for recurrences, incomplete coil embolization or its complications. Our objective was to assess the surgical management in such patients. This was a retrospective analysis of the patients who were initially treated with endovascular embolization and later managed surgically with clipping either for unsuccessful coiling, recurrence of aneurysm or post-procedural complication, between 2003 and 2007. Anatomical results were excellent in all five patients, and all the aneurysms were totally excluded from the circulation. All patients had good recovery. None of the patients suffered any major intraoperative or postoperative complication. Neurosurgical management of intracranial aneurysms previously treated with endovascular therapy is an emerging challenge, but with proper patient selection and careful planning, this subset of aneurysms can be managed with good results.
Primary Extradural Non-Hodgkin's Lymphoma
Rakesh Kapoor, Vinay Kumar, S.C. Sharma
JK Science : Journal of Medical Education & Research , 2006,
Abstract: A 28 years old male presented to our institute with 3 months history of paraparesis with decreased sensationover left foot and loss of bladder and bowel control .The diagnostic work up revealed an extradural massat spinal level L3 L4.Had laminectomy and the tumour was sub totally resected. Histological examinationrevealed non hodgkin's lymphoma. The patient was worked up for disease anywhere else and was confirmedto have primary extra-dural non-hodgkin's lympoma(PENHL). Patient was treated with corticosteroides,adjuvant radiotherapy and chemotherapy. The residual tumour completely disappeared and patient isliving normal healthy life and is walking without support after 9 years of follow-up.
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