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Search Results: 1 - 10 of 419924 matches for " M. Ananda Kumar "
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Assessing the Fault Proneness Degree (DFP) by Estimating the Impact of Change Request Artifacts Correlation
Rudra Kumar M,A Ananda Rao
Computer Science , 2015,
Abstract: Exploring the impact of change requests applied to a software maintenance project helps to assess the fault-proneness of the change request to be handled further, which is perhaps a bug fix or even a new feature demand. In practice, the major development community stores change requests and related data using bug tracking systems such as Bugzilla. These data, together with the data stored in a versioning system, such as Concurrent Versioning Systems, are a valuable source of information to create descriptions and also can perform useful analyzes. In our earlier work, we proposed a novel statistical bipartite weighted graph-based approach to assessing the degree of fault-proneness of the change request and Change Request artifacts. With the motivation gained from this model, here we propose a novel strategy that estimates the degree of fault-proneness of a change request by assessing the impact of a change request artifact towards fault-proneness that considers the correlation between change requests artifact as another factor, which is in addition to our earlier strategy. The proposed model can be titled as Assessing the Fault Proneness Degree of Change Request Artifacts by estimating the impact of change requests correlation (DFP-CRC). As stated in our earlier model, the method DFP-CRC also makes use of information retrieval methods to identify the change request artifacts of the devised change request. And further evaluates the degree of fault-proneness of the Change Requests by estimating the correlation between change requests. The proposed method is evaluated by applying on concurrent versioning and Change request logs of the production level maintenance project.
Efficient Cancer Classification using Fast Adaptive Neuro-Fuzzy Inference System (FANFIS) based on Statistical Techniques
K.Ananda Kumar,Dr.M.Punithavalli
International Journal of Advanced Computer Sciences and Applications , 2011,
Abstract: The increase in number of cancer is detected throughout the world. This leads to the requirement of developing a new technique which can detect the occurrence the cancer. This will help in better diagnosis in order to reduce the cancer patients. This paper aim at finding the smallest set of genes that can ensure highly accurate classification of cancer from micro array data by using supervised machine learning algorithms. The significance of finding the minimum subset is three fold: a) The computational burden and noise arising from irrelevant genes are much reduced; b) the cost for cancer testing is reduced significantly as it simplifies the gene expression tests to include only a very small number of genes rather than thousands of genes; c) it calls for more investigation into the probable biological relationship between these small numbers of genes and cancer development and treatment. The proposed method involves two steps. In the first step, some important genes are chosen with the help of Analysis of Variance (ANOVA) ranking scheme. In the second step, the classification capability is tested for all simple combinations of those important genes using a better classifier. The proposed method uses Fast Adaptive Neuro-Fuzzy Inference System (FANFIS) as a classification model. This classification model uses Modified Levenberg-Marquardt algorithm for learning phase. The experimental results suggest that the proposed method results in better accuracy and also it takes lesser time for classification when compared to the conventional techniques.
Total Electron Content and Anomalous Appearance of GPS Satellites as Pointers to Epicentre Identification of Major Japan Earthquake of 2011  [PDF]
Minakshi Devi, Ananda Kumar Barbara
Positioning (POS) , 2012, DOI: 10.4236/pos.2012.31002
Abstract: The paper presents an analysis of variations in Total Electron Content (TEC) observed through Global Positioning System (GPS) at Guwahati (26?10'N, 91?45'E), in relation to the Japan Earthquakes (EQs) of March 9 and 11, 2011. For this purpose, the azimuthal positions and trajectories of abnormally increased number of satellites at the epicentre location appearing into the Field Of View (FOV) of GPS antenna at Guwahati and consequent pseudo enhancement in TEC are taken as inputs. The paper discusses how the analysis results could provide warning alarms of two earthquakes possibly one on March 8 or 9 and the other on March 11 or 12, 2011 with epicenter positions around 135?E to 145?E and 35?N to 40?N, that coincides with location of Japan Earthquakes. A projected forecast on EQ magnitude of M > 8.5 is also made. The explanations to the observed modifications in TEC features and abnormal increase in number of satellites are purported to be the result of coupling between lithosphere and troposphere forced in by pre-earthquake processes that had spread the zone of activities to as far as Guwahati.
N1-(4-Methylphenyl)piperidine-1,4-dicarboxamide
Arun M. Islor,M. R. Jagadeesh,H. M. Suresh Kumar,R. Ananda Kumari
Acta Crystallographica Section E , 2012, DOI: 10.1107/s1600536812047836
Abstract: In the title compound, C14H19N3O2, the heterocycle adopts a 1C4 conformation with the N atom being one of the flap atoms. In the crystal, classical N—H...O hydrogen bonds and C—H...O contacts connect the molecules into a three-dimensional network.
Demography and Etiology of Congenital Cataract in a Tertiary Eye Centre of Kathmandu, Nepal
Ananda Kumar Sharma,D N Shah,M P Upadhyay,M Thapa,G. S. Shrestha
Health Renaissance , 2014, DOI: 10.3126/hren.v12i1.11975
Abstract: Background: Congenital Cataract is the most important cause of treatable childhood blindness. Rubella is one of the major causes of preventable disease in many countries. There are scanty reports on congenital cataract in Nepal. Objective: To find out the demographic and etiological factors of congenital cataract in children. Method: In a hospital based cross sectional study, 46 children with congenital cataract were evaluated to find out morphology of cataract, laterality, associated ocular and systemic abnormality, visual status and etiology of cataract. Assessment included antenatal, birth and neonatal history, a detailed eye examination in slit lamp or the operating microscope under general anaesthesia, serum serology for TORCH infections, random blood sugar, urine reducing substance and thyroid profile. Result: Among 46 children with congenital cataract, 76.1% children presented before 5 years of age and 78.2% had bilateral onset. Male to female ratio was 1.3:1. Most of the children were legally blind (79.3%) in cataractous eye. Family history of congenital cataract was present in 15.2% cases. The most common mode of presentation was leukocoria in 91.3%. Microcornea (28.3%), resolved uveitis (13.0%), and iris atrophy (8.7%) were the most common ocular associations. Delayed developmental milestone (21.7%) and cardiac anomalies (10.9%) were the most common systemic anomalies. Lamellar cataract (51.3%) was the most common morphology of cataracts observed. The maternal infection was the major cause of congenital cataract in 17.4% cases with predominantly rubella infection in 13% cases. Conclusion: Most of the children with cataract are legally blind. Maternal infection in the antenatal period is the major cause of congenital cataract. DOI: http://dx.doi.org/10.3126/hren.v12i1.11975 ? ? Health Renaissance 2014;12(1):3-10
An Approach to Test Case Design for Cost Effective Software Testing
Kiran Kumar J,A. Ananda Rao,M. Gopi Chand,K. Narendar Reddy
Lecture Notes in Engineering and Computer Science , 2009,
Abstract:
ZigBee Based Home Security Alert System: An Integrated Approach
C.P. Jeba Samuel,S. Prakash,M. Ananda Kumar,D. Manivannan
Journal of Artificial Intelligence , 2013,
Abstract: In remote home monitoring security system, embedded devices play a vital role. In this study, GSM, ARM and ZigBee are used to establish a security for smart home. In this study, LPC2148 is used as Microcontroller Unit (MCU), Resistance Temperature Detectors (RTD) to observe temperature, smoke sensor to detect the presence of smoke and vibration sensor over doors and windows to detect forced entry, overall system safeguard the home from burglary. On entering the correct password, MCU disarms the security feature else it activates the alarms and sends image of the burglar to amenable persons through ZigBee and whenever there is smoke or fire MCU sends SMS to owner as well it automatically activates safety measures like, opening window turns on the exhaust fan and sprinkler.
Nimotuzumab in Management of Brain Stem Glioma: A Case Report  [PDF]
K. S. Kirushna Kumar, P. Ananda Selvakumar, Krishna Kumar Rathinam
Journal of Cancer Therapy (JCT) , 2017, DOI: 10.4236/jct.2017.82018
Abstract: Brainstem glioma is rare tumour in adults accounting for 1% - 2% of intracranial gliomas. In this case study, a 28-year-old female diagnosed with BG, and lesions were observed in the pons and medulla region of the brain stem. She was initially treated with radiotherapy (54 Gy in 30 fractions for 6 weeks) but no change in her clinical condition and size of tumor was observed. Temozolomide (250 mg/daily for 5 days) was prescribed as first line chemotherapy. After completion of three cycles of Temozolomide, patient presented with diplopia and MRI showed increase in the size of lesions. After unsatisfactory response to radiation and chemotherapy, the patient was treated with Nimotuzumab therapy. MRI scan demonstrated the reduction of lesion size after 8 cycles of Nimotuzumab (200 mg/week). This treatment continued for another 8 cycles and the MRI scan of patients showed a significant reduction in lesion size. Nimotuzumab was found to be an effective and safe treatment option for brainstem glioma patient who was resistant to radiotherapy and chemotherapy.
Herpes Simplex Keratitis – an unusual clinical presentation
Ananda Kumar Sharma
Nepalese Journal of Ophthalmology , 2014, DOI: 10.3126/nepjoph.v6i1.10787
Abstract: DOI: http://dx.doi.org/10.3126/nepjoph.v6i1.10787 Nepal J Ophthalmol 2014; 6 (2): 125-126
Protein engineering of delta-endotoxins of Bacillus thuringiensis
Saraswathy,Nachimuthu; Kumar,Polumetla Ananda;
Electronic Journal of Biotechnology , 2004,
Abstract: bacillus thuringiensis (bt) is a valuable environment-friendly biopesticide, which occupies 90% of the world biopesticide market. its insecticidal properties are attributed to the presence of d-endotoxins which are synthesized during the sporulation phase of the bacterium. d-endotoxin or crystal toxin is a multi-domain protein molecule comprising of three distinct domains. domain i is made of seven a-helices, domain ii comprises three antiparallel b sheets, which are folded into loops and domain iii is made of a b sandwich of two antiparallel b strands. molecular studies on the structure and functional properties of different d-endotoxins revealed that the domain i by virtue of its membrane spanning hydrophobic and amphipathic a-helices is capable of forming pores in the cell membranes of the larval midgut. domain ii being hyper variable in nature determines the insecticidal specificity of a toxin and domain iii is involved in varied functions like structural stability, ion channel gating, binding to brush border membrane vesicles and insecticidal specificity. recent studies on toxin aggregation and interaction revealed that the three domains interact closely to bring about the insecticidal activity of bt. in this review we describe the protein engineering studies conducted on different d-endotoxins which led to an understanding of their molecular mode of action and construction of novel toxins with enhanced insecticidal activity and specificity.
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