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Search Results: 1 - 10 of 503029 matches for " Mónica; Rojas H "
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Embriopatía por isotretinoína: Un da?o evitable
Troncoso Sen,Mónica; Rojas H,Carla; Bravo C,Eduardo;
Revista médica de Chile , 2008, DOI: 10.4067/S0034-98872008000600012
Abstract: retinoic acid is a widely used drug in the treatment of cystic acné. it has teratogenic effects that depend on the gestational period in which it is used. we report a seven months of female whose mother was exposed to retinoic acid in both pregestational and gestational periods. she had a retardation of psychomotor development and a brain mri showed frontal atrophy and a malformation of the posterior fossa. we discuss the mechanisms ofthe teratogenic effeets of retinoic acid
Embriopatía por isotretinoína: Un da o evitable Isotretinoin embryophaty: Report of one case
Mónica Troncoso Sen,Carla Rojas H,Eduardo Bravo C
Revista médica de Chile , 2008,
Abstract: Retinoic acid is a widely used drug in the treatment of cystic acné. It has teratogenic effects that depend on the gestational period in which it is used. We report a seven months of female whose mother was exposed to retinoic acid in both pregestational and gestational periods. She had a retardation of psychomotor development and a brain MRI showed frontal atrophy and a malformation of the posterior fossa. We discuss the mechanisms ofthe teratogenic effeets of retinoic acid
Lipopolyamine-mediated transfection of reporter plasmids into a fish cell line
Villalobos,Patricio; Rojas,M. Verónica; Conejeros,Pablo; Marshall,Sergio H.;
Electronic Journal of Biotechnology , 1999,
Abstract: conditions have been optimised to transfect the fish cell line chse-214 to measure expression, maintenance and putative chromosomal integration of the reporter gene luc, spliced into two versions of an expression vector. the first is pcmvl, and the second p103, a novel pcmvl-derived plasmid to which a highly conserved tandem repeat from the salmon genome was added in an inverted configuration flanking the luc gene to promote its chromosomal integration. a minimal ratio of one to one, lipopolyamine carrier to plasmid dna, was enough to efficiently transfect the cell line to follow the fate of target dnas up to five cell passages. in this time-span we demonstrated the maintenance of the foreign dna in the cells, the concomitant expression of the reporter gene, and a higher stability of p103 over the control plasmid which might suggest a higher potential for integration. thus, we define an efficient model system for future in vitro evaluation of potential target genes of commercial interest for fish transgenesis
Vaccination with Recombinant Adenoviruses Expressing the Peste des Petits Ruminants Virus F or H Proteins Overcomes Viral Immunosuppression and Induces Protective Immunity against PPRV Challenge in Sheep
José M. Rojas, Héctor Moreno, Félix Valcárcel, Lourdes Pe?a, Noemí Sevilla, Verónica Martín
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0101226
Abstract: Peste des petits ruminants (PPR) is a highly contagious disease of small ruminants caused by the Morbillivirus peste des petits ruminants virus (PPRV). Two recombinant replication-defective human adenoviruses serotype 5 (Ad5) expressing either the highly immunogenic fusion protein (F) or hemagglutinin protein (H) from PPRV were used to vaccinate sheep by intramuscular inoculation. Both recombinant adenovirus vaccines elicited PPRV-specific B- and T-cell responses. Thus, neutralizing antibodies were detected in sera from immunized sheep. In addition, we detected a significant antigen specific T-cell response in vaccinated sheep against two different PPRV strains, indicating that the vaccine induced heterologous T cell responses. Importantly, no clinical signs and undetectable virus shedding were observed after virulent PPRV challenge in vaccinated sheep. These vaccines also overcame the T cell immunosuppression induced by PPRV in control animals. The results indicate that these adenovirus constructs could be a promising alternative to current vaccine strategies for the development of PPRV DIVA vaccines.
Valoración de la formación recibida usando un perfil de referencia basado en competencias profesionales
Maldonado Rojas,Mónica;
Educación Médica , 2007, DOI: 10.4321/S1575-18132007000500007
Abstract: introduction: the professional formation is today promoting the implementation of educational options based on competences. this has the purpose of establishing a reference profile, based on professional competences for the medical technology career of the university of talca, using them as indicators, to know the self perception which graduate students have, regarding the level acquired during their formation. material and method: according to this, an evaluative and descriptive investigation, throughout a self applied survey was carried out. it contained a group of indicators corresponding to previously settled competences in a reference profile where its structure considers different areas, validated by experts, determining the consistency degree through serafine coefficient. the construction of the information was carried out according to the graduate answers decoded and represented in percentages and later analyzed under interpretative categories. results: the evaluation considers the percentage of that valued the profile of the competences by area of performance in the highest levels. the obtained results were: for the assistance area 72.9%, the investigation a 59%, the teaching a 44%, the administrative area a 27.1% and the personal-social area a 91.3%. conclusions: the evaluation made by graduate students about their formation reflects the valued given to the skills acquired in their formation the interpretative categories, the personal-social area is highly evaluated, indicating a great formation advantage, the assistance and investigation area are satisfactory. the teaching and administration area fairly satisfactory. however the last one is considered the lowest. curriculum effective it is adapted to assure the profile of competences but one is due to review with the objective to incorporate contents for the profit of those deficient.
DIAGNóSTICO DE LA COMPETENCIA PARA LA COMUNICACIóN EN DIRECTIVOS QUE CURSAN LA MAESTRíA EN DIRECCIóN
Mónica Queris Rojas
Ingeniería Industrial , 2009,
Abstract: El término gestión por competencias, crece en importancia en diversas partes del mundo, ocupando cada vez un papel más central en empresas y centros de educación superior. En este aspecto, las experiencias en América Latina, están mostrando que lo más importante no es quién certifica, sino cómo se desarrolla el proceso. En nuestro país su incorporación es aun mínima en términos reales, aunque algunas experiencias han sido introducidas en diversas organizaciones en el dise o de puestos de trabajo y ocupacionales [1]. Este trabajo pretende demostrar un diagnóstico sobre la competencia para la comunicación en directivos que han cursado y cursan la maestría en Dirección a partir de la aplicación de diferentes técnicas.
Rese a de "Psicología del humor: un enfoque integrador" de Martin, R. A.
Mónica Reyes Rojas
Revista Latinoamericana de Psicología , 2010,
Abstract:
Valoración de la formación recibida usando un perfil de referencia basado en competencias profesionales Valuation the formation using a profile of reference based on professional competences
Mónica Maldonado Rojas
Educación Médica , 2007,
Abstract: Introducción: La formación profesional está hoy en día promoviendo la implementación de opciones educativas basadas en modelos por competencias. El presente trabajo tuvo como propósito establecer un perfil de referencia basado en competencias profesionales para la carrera de Tecnología Médica de la Universidad de Talca y usando éstas como indicadores, conocer la auto percepción que tienen los egresados respecto del grado en que fueron adquiridas durante su formación. Material y métodos: Se realizó una investigación de tipo exploratoria, mediante una encuesta autoaplicada que contenía un conjunto de indicadores que correspondían a competencias establecidas previamente en un perfil de referencia, cuya estructura considera diferentes áreas de desempe o. El perfil fue validado por juicio de expertos, determinando el grado de congruencia a través del coeficiente de Serafine. La construcción de la información se realizó a partir de las repuestas, las que fueron codificadas y representadas en porcentajes y posteriormente analizadas bajo categorías interpretativas. Resultados: La evaluación que se hace considera el porcentaje de egresados que valoró el logro de las competencias por área de desempe o en los niveles más altos. Los resultados obtenidos fueron: Para el área asistencial el 72,9 %, para el área investigación un 59 %, para el área de docencia un 44%, para el área administrativa un 27,1% y para el área personal-social un 91,3 %. Conclusiones: Siguiendo el criterio de categorías interpretativas, el área personal social indica una gran fortaleza de la formación, el área asistencial y el área investigación se encuentran en un nivel satisfactorio y las áreas docencia y administración en niveles medianamente satisfactorio, siendo esta última la gran falencia de la formación. El currículo vigente es adecuado para asegurar el logro de gran número de competencias, pero se debe revisar con el objetivo de incorporar contenidos para el logro de aquellas deficientes. Introduction: The professional formation is today promoting the implementation of educational options based on competences. This has the purpose of establishing a reference profile, based on professional competences for the Medical Technology career of the University of Talca, using them as indicators, to know the self perception which graduate students have, regarding the level acquired during their formation. Material and method: According to this, an evaluative and descriptive investigation, throughout a self applied survey was carried out. It contained a group of indicators corresponding to previou
Quimiotaxis bacteriana y flavonoides: perspectivas para el uso de probióticos
Galicia-Jiménez, Mónica Marcela;Sandoval-Castro, Carlos;Rojas-Herrera, Rafael;Maga?a-Sevilla, Héctor;
Tropical and subtropical agroecosystems , 2011,
Abstract: the application of different diets have focused on seeking greater production in the ruminant animal feed varies, thus affecting rumen microbial population, however, the production efficiency of ruminants has been reported inconsistently. furthermore, studies have been conducted secondary metabolites secreted by plants and has been having a function of attractant or repellent in plant-microbe interactions. so our goal is to integrate knowledge of rumen bacteria-particle interactions of forage used for food and flavonoids as stimulants in the flagellar movement. thus, understanding the signaling pathways used by rumen bacteria to colonize food particles and degradation. research and implement programs using genomic tools to help us discover chemotactic genes in rumen bacteria that contribute to elucidate principles governing the communication of microbial populations, their interactions and main products of microbial metabolism, and thus could raise the handling of ruminal fermentation, creating the probiotic cultures for cattle.
MICROCALCIFICACIONES BIRADS 4: EXPERIENCIA DE 12 A?OS
Ricci A,Paolo; Cruz C,Adolfo; Rodríguez P,Mario; Sepúlveda M,Héctor; Galleguillos F,Isabel; Rojas Z,Francisco; Pe?a M,Verónica; Carvajal G,Rodrigo; Bravo M,María; Castillo I,Rodrigo; Nú?ez P,Claudia;
Revista chilena de obstetricia y ginecología , 2006, DOI: 10.4067/S0717-75262006000600004
Abstract: objective: to know the clinical and histological association in presence of microcalcifications birads 4. method: retrospective analysis of 204 patients with microcalcifications birads 4, under mastectomy in barros luco-trudeau hospital between january 1993 and december 2004. the patients were marked previously with metallic harpoon in zone of microcalcifications and later radiological control of the surgical piece. results: the location of birads 4 microcalcifications was the left breast in 52% (106 cases), right breast 42% (85 cases), and both 6% (13 cases). the deferred biopsy showed 17 cases with mammary cancer (8.3 %), fibrocystic condition 197 cases (96.6%), non atypical hyperplasia 49 cases (24%), atypical hyperplasia 17 cases (8.3%), duct ectasia 7 cases (3.4%), papillomatosis 6 cases (2.9%), chronic mastitis 4 cases (2%), fibroadenoma 4 cases (2%), galactophoritis 2 cases (1%) and fat necrosis 2 cases (1%). conclusion: the birads 4 microcalcifications constitute an important mammography finding to be associated with breast cancer and high risk injuries in a high percentage
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