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Search Results: 1 - 10 of 816745 matches for " Márcio A. C. Arruda "
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Outcome Determinants of Stroke in a Brazilian Primary Stroke Center
Gustavo W. Kuster,Lívia A. Dutra,Israel P. Brasil,Evelyn P. Pacheco,Márcio A. C. Arruda,Cristiane Volcov,Renan B. Domingues
Stroke Research and Treatment , 2014, DOI: 10.1155/2014/194768
Abstract: Background. Stroke mortality in Brazil is one of the highest among Western countries. Nonetheless, stroke outcome determinants are still poorly known in this country. In this study we evaluate outcome determinants of stroke in a primary stroke center in S?o Paulo, Brazil. Methods. We evaluated demographic, clinical, and outcome data of patients with ischemic stroke (IS), transient ischemic attack (TIA), and intracerebral hemorrhage (ICH) admitted at “Hospital Paulistano,” S?o Paulo, Brazil. In-hospital mortality and functional outcome determinants were assessed. Univariate and binary logistic regression analysis were performed. Results. Three hundred forty-one patients were included in the study, 52.2% being male with years. The stroke type distribution was IS: 59.2%, TIA: 29.6%, and ICH: 11.1%. ICH was associated with greater severity and poorer functional outcome. The determinants of poorer functional outcome were higher NIHSS, lower Glasgow score, and lower oxygen saturation level. The most important mortality determinant was the presence of visual symptoms. Conclusions. The stroke mortality and stroke outcome determinants found in the present study do not remarkably differ from studies carried out in developed countries. Stroke prognosis studies are crucial to better understand the high burden of stroke in Brazil. 1. Introduction Stroke is the first cause of disability, the second cause of cognitive impairment, and the third cause of death in the world [1]. Two-thirds of all stroke deaths occur in low- and middle-income countries, including Latin America countries; however, stroke has been poorly studied in these regions [2]. In Brazil, the largest country in the region, stroke is the leading cause of death and disability and the stroke mortality is one of the highest among Western countries [3, 4]. The causes of the high stroke burden in Brazil remain speculative. One possibility is that the prevalence of stroke is higher in Brazil than in other regions. Some prevalence studies were carried in Brazil but the data are not sufficient to provide an overview of stroke prevalence in Brazil, since most of these studies were carried out in specific regions that do not necessarily reflect the whole country reality [5]. Other potential explanations rely on medical assistance deficiencies, mostly driven by socioeconomic inequality. In fact, previous studies showed that the majority of patients are assisted in public hospitals where diagnostic and therapeutic resources are scarce [6–9]. However, the negative impact of these discrepancies on stroke outcome in
Bioequivalence study of four different trademarks of enalapril maleate in spontaneously hypertensive rats
Baracho, Nilo César do Vale;Arruda, Guilherme D'Andréa Saba;Alves, Lidinei José;Carneiro, Márcio Felipe Salomon;Siqueira, Matheus Teodoro Grilo;Arango, Héctor Gustavo;Reis, José Marcos dos;
Acta Cirurgica Brasileira , 2008, DOI: 10.1590/S0102-86502008000200010
Abstract: introduction: high blood pressure is a systemic disease which has major clinical and psycho-social repercussions, involves a high morbidity-mortality rate and generates high costs for the health system. its treatment involves the use of antihypertensive drugs, which are commercialized as trademark, generic or similar drugs. purpose: to verify the antihypertensive effect produced by a similar dose of different trademarks of enalapril maleate in spontaneously hypertensive rats (shr). methods: fifteen mg/kg of enalapril maleate were administered by gavage in 50 shr rats and their blood pressure was verified through tail plethysmography every three days in a period of 16 days. results: the group treated with reference drug has shown a significant reduction on blood pressure levels when compared to the control group. thus, treatments with enalapril maleate of generic, similar-a and similar-b brands have also shown significant reduction on animals' blood pressure. conclusion: the use of generic drug and similars (a and b) drugs in the same doses and for the same period of time has not shown significant difference regarding the reference drug, which suggests that the brands tested are bioequivalent.
Computer Analysis of Electromagnetic Transients in Grounding Systems Considering Variation of Soil Parameters with Frequency  [PDF]
Marco A. O. Schroeder, Márcio M. Afonso, Tarcísio A. S. Oliveira, Sandro C. Assis
Journal of Electromagnetic Analysis and Applications (JEMAA) , 2012, DOI: 10.4236/jemaa.2012.412066
Abstract: This paper presents a mathematical model to calculate transients in grounding systems. The derived equations arise from direct application of basic electromagnetic equations in frequency domain, whose solution is obtained by the application of the Moment Methods. A formulation based on experimental measurements is applied to quantify the soil parameters for each frequency. The unified approach is applied in the calculation of the grounding impedance of horizontal electrodes. Results show that the inclusion of frequency dependence of the soil parameters leads to a reduction of the values of grounding impedance, in comparison with results for soils with parameters independent of frequency.
Analytical quality in environmental studies: uncertainty evaluation of chemical concentrations determined by INAA
Fran?a, Elvis Joacir de;Fernandes, Elisabete A. De Nadai;Bacchi, Márcio Arruda;Saiki, Mitiko;
Brazilian Archives of Biology and Technology , 2006, DOI: 10.1590/S1516-89132006000200016
Abstract: instrumental neutron activation analysis (inaa) is a measurement technique of high metrological level for the determination of chemical elements. in the context of biota/fapesp program, leaves of trees have been evaluated by inaa for biomonitoring purposes of the atlantic forest. to assure the comparability of results in environmental studies, a leaf sample of marlierea tomentosa (myrtaceae family) showing the lowest concentrations of chemical elements was selected for the evaluation of analytical quality of the determination under unfavorable conditions. nevertheless, the homogeneity of chemical concentrations of sample at the 95% of confidence level has been achieved and inaa has presented repeatability of 2% for the determination of br, co, cs, fe, k, na, rb and sr, the uncertainty could have been overestimated. for the evaluation of uncertainty due to the variability of chemical concentrations in the sample, jackknife and bootstrap methods were used to estimate the maximum expected percent standard deviation. the uncertainty budget was considered adequate for the reporting chemical concentrations of environmental samples determined by inaa.
Redes dinamicas cognitivas aplicadas no controle supervisório de um fermentador
Mendon?a, Márcio;Arruda, L. V. R.;Neves-Jr, Flávio;
Sba: Controle & Automa??o Sociedade Brasileira de Automatica , 2011, DOI: 10.1590/S0103-17592011000400003
Abstract: this paper uses dynamic cognitive networks (dcn) as an intelligent tool for supervisory control. the dcns are an evolution of fuzzy cognitive maps (fcm). intelligent systems and tools use expert knowledge to build models with inference and / or decision taking abilities. a supervisory control architecture for an alcoholic fermentation process is developed from the acquisition of empirical knowledge from an expert. the objective of the supervisor is to operate the process in normal and critical situations. for this, we propose the use of a dcn model with new types of concepts and relationships that not only represent cause-effect as in fcm models. simulation results are presented to validate the architecture developed.
Study of Corrosion Resistance of Laser Welded Au-Pd-Ag-In Alloy Using Electrochemical Techniques  [PDF]
Márcio L. Dos Santos, Heloísa A. Acciari, Carla S. Riccardi, Antonio C. Guastaldi
Materials Sciences and Applications (MSA) , 2011, DOI: 10.4236/msa.2011.27098
Abstract: The aim of this work was to evaluate the corrosion resistance of AuPdAgIn alloy, submitted to laser beam welding, in 0.9% NaCl solution, using electrochemical techniques. Measures of the open circuit potential (OCP) versus time were applied to electrochemical experiments, as well as potentiodynamic direct scanning (PDS) and electrochemical impedance spectroscopy (EIS) on AuPdAgIn alloy, submitted to laser beam welding in 0.9% NaCl solution. Some differences observed in the microstructure can explain the results obtained for corrosion potential, Ecorr, and corrosion resistance, Rp. EIS spectra have been characterized by distorted capacitive components, presenting linear impedance at low frequencies, including a non-uniform diffusion. The area of the laser weld presented corrosion potential slightly superior when compared to the one of the base metal. The impedance results suggest the best resistant corrosion behavior for laser weld than base metal region. This welding process is a promising alternative to dental prostheses casting.
Ultrasound-assisted extraction of Ca, K and Mg from in vitro citrus culture
Arruda, Sandra C. C.;Rodriguez, Adriana P. M.;Arruda, Marco A. Z.;
Journal of the Brazilian Chemical Society , 2003, DOI: 10.1590/S0103-50532003000300023
Abstract: an ultrasound extraction procedure for ca, k and mg from in vitro plant cultures is proposed, comparing cultures of different embryogenic levels of citrus sinensis and citrus limonia, employing ultrasound energy. parameters related to metals extraction, such as plant material sampling, acid concentration and sonication time were investigated. for accuracy check, the proposed ultrasound extraction procedure was compared with a microwave-assisted digestion procedure and no differences in the results were verified at 95% of the confidence level. with this simple and accurate extraction procedure, it was possible to determine differences in ca, k and mg concentrations during citrus embryo formation/development and between cultures (embryogenic and non-embryogenic). finally, the ultrasound extraction method demonstrated to be an excellent alternative for handless sampling and operational costs.
Ultrasound-assisted extraction of Ca, K and Mg from in vitro citrus culture
Arruda Sandra C. C.,Rodriguez Adriana P. M.,Arruda Marco A. Z.
Journal of the Brazilian Chemical Society , 2003,
Abstract: An ultrasound extraction procedure for Ca, K and Mg from in vitro plant cultures is proposed, comparing cultures of different embryogenic levels of Citrus sinensis and Citrus limonia, employing ultrasound energy. Parameters related to metals extraction, such as plant material sampling, acid concentration and sonication time were investigated. For accuracy check, the proposed ultrasound extraction procedure was compared with a microwave-assisted digestion procedure and no differences in the results were verified at 95% of the confidence level. With this simple and accurate extraction procedure, it was possible to determine differences in Ca, K and Mg concentrations during Citrus embryo formation/development and between cultures (embryogenic and non-embryogenic). Finally, the ultrasound extraction method demonstrated to be an excellent alternative for handless sampling and operational costs.
Avalia o da resistência de isolinhas de feijoeiro a diferentes patótipos de Colletotrichum lindemuthianum, Uromyces appendiculatus e Phaeoisariopsis griseola
Ragagnin Vilmar Antonio,Alzate-Marin Ana Lília,Souza Thiago Livio P. O.,Arruda Klever Márcio A.
Fitopatologia Brasileira , 2003,
Abstract: Isolinhas de feijoeiro (Phaseolus vulgaris)derivadas da cultivar Rudá, com gr os do tipo "carioca", contendo os genes de resistência à antracnose (Co-4 do cv. TOou Co-6 do cv. AB 136 ou Co-10 do cv. Ouro Negro), ferrugem (gene do cv. Ouro Negro) e mancha-angular (phg-1 da linhagem AND 277) foram desenvolvidas pelo Programa de Melhoramento do Feijoeiro do BIOAGRO/UFV, para serem utilizadas na piramida o desses genes em uma única cultivar. Este trabalho teve como objetivo determinar o espectro de resistência dessas isolinhas a diferentes patótipos de Colletotrichum lindemuthianum, Uromyces appendiculatus e Phaeoisariopsis griseola, visando selecionar as linhagens mais similares aos progenitores doadores quanto à sua resistência. Para isto, foram conduzidas inocula es artificiais com 18 patótipos de C. lindemuthianum, dez patótipos de U. appendiculatus e quatro patótipos de P. griseola. Para resistência à antracnose, foi selecionada uma linhagem do cruzamento Rudá x TO, homozigota resistente a 17 patótipos, uma linhagem do retrocruzamento Rudá x AB 136, homozigota resistente a 15 patótipos e uma linhagem do cruzamento Rudá x Ouro Negro, homozigota resistente a 15 patótipos de C. lindemuthianum. Para resistência à ferrugem, uma linhagem do cruzamento Rudá x Ouro Negro, apresentou-se homozigota resistente aos dez patótipos de U. appendiculatus testados. Para resistência à mancha-angular, uma linhagem do cruzamento Rudá x AND277 apresentou-se homozigota resistente aos quatro patótipos de P. griseola inoculados. As melhores isolinhas est o sendo intercruzadas visando a piramida o de genes de resistência à ferrugem, à antracnose e à mancha-angular e o desenvolvimento de cultivares essencialmente derivadas da cultivar Rudá.
Oxidative Stress Biomarkers Response to Exercise in Brazilian Junior Soccer Players  [PDF]
Camila S. C. da Costa, Márcio A. Barbosa, Juliano Spineti, Cristiana M. Pedrosa, Anna Paola T. R. Pierucci
Food and Nutrition Sciences (FNS) , 2011, DOI: 10.4236/fns.2011.25057
Abstract: The purpose was to analyze biomarkers of oxidative stress and muscle damage in junior soccer players undergoing intermittent exercise to verify the biochemical changes. Ten trained, healthy male soccer players (age 18.3 ± 0.7 years, body mass 74.3 ± 7.4 kg, height 175.5 ± 6.7 cm, body mass index 24.14 ± 1.15 kg/m2; mean ± SD) from the junior cate-gory of an elite Brazilian football association participated in this study. They accomplished a running test (Loughbo-rough Intermittent Shuttle Test) which simulates common soccer activity patterns. Blood samples were collected before, during and immediately after the exercise for glucose, lactate, creatinine, urea, ascorbic acid, total plasma antioxidant potential, lipid hydroperoxides, malondialdehyde and creatine kinase concentrations. During the exercise no changes were observed in biomarkers, but, immediately after there was a significant decrease in total plasma antioxidant potential (ranging from 650.37 ± 66.53 µmol.L-1 to 559.95 ± 91.38 µmol.L-1, p < 0.05) while malondialdehyde and creatine kinase had increased (ranging, respectively, from 6.69 ± 0.81 µmol.L-1 to 8.35 ± 0.83 nmol.L-1 and from 272.01 ± 49.67 U.I.?L-1 to 304.65 ± 39.13 U.I.?L-1, p < 0.05). Findings suggest that the exercise protocol induced significant changes in oxidative stress selected biomarkers in the early stage of recovery. Thus, taking into account that soccer players’ competitive careers initiate very precociously being under constant physical exhaustion, further research on junior soccer players’ physiology and health are important for more effective physical and nutritional programming.
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