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Search Results: 1 - 10 of 406179 matches for " M Zahoor ul Hassan Dogar "
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M Zahoor ul Hassan Dogar
The Professional Medical Journal , 2000,
Abstract: OBJECTIVE: To find out the effect of vitamin C deficiency on different fractions of blood cholesterol anddevelopment of hypertension. DESIGN: Prospective comparative study. SETTING: Punjab Institute ofCardiology Lahore. PERIOD: From Oct 1995 to Oct 1996. SUBJECTS AND METHODS: Ninety fourmale adults (sixty three hypertensive and thirty one normotensive) subjects of 40-55 years age. RESULTS:The plasma ascorbic acid (PAA) levels were 0.530±0.086 mg/dl, 0.374±0.68 mg/dl and 0.218±0.077 mg/dlin the normotensive, mild and moderate hypertensive subjects. The Total Cholesterol (TC) was 182.37±24.08mg/dl, 205.96±15.79 mg/dl and 261.45±57.40 mg/dl in the above groups. Similarly the serum levels of HDLCholesterol (HDL-C) were 45.25±4.35 mg/dl, 42.36±2.76 mg/dl and 37.66±3.45 mg/dl and LDL Cholesterol(LDL-C) levels were 102.49±29.07 mg/dl, 128.98±21.69 mg/dl and 175.32±63.72 mg/dl respectively. Theresults of blood ascorbic acid along with various fractions of cholesterol, were significantly differed in theabove groups and the data indicated clearly that PAA (r=-10.891) and HDL-C (r=-0.658) were correlatednegatively while TC (r=+0.616) and LDL-C (r=+0.562) were related positively with the diastolic blood pressure.The results also showed that Plasma Ascorbic Acid (PAA) was correlated negatively with the TC and LDL-Cand positively with the HDL-C levels. CONCLUSIONS: It is suggested that plasma ascorbic acid deficiencymay be responsible for derangements of various fractions of cholesterol resulting in atherogenic vasculardamage leading to hypertension.
M. Zahoor ul Hassan Dogar
The Professional Medical Journal , 2001,
Abstract: Viral Hepatitis “An AIDS of Pakistan”, a poster exhibited on a local walk against Hepatitis, depictsthe severity of the disease. A survey published recently in a daily newspaper narrated that about10-25% of total population in Pakistan is either suffering from, or is included among carrier ofthis disease. Among them, the common prevalent types are hepatitis B & C. This article is a reviewcompilation of the various research materials published in international journals, related actually to Pakistanor Pakistani population settled elsewhere in the world.
M. Zahoor ul Hassan Dogar
The Professional Medical Journal , 1997,
Abstract: The study was designed to evaluate the serum iron and zinc status of young healthy individuals with the views toset some physiological norms for reference use in future. Seventy one young healthy medical students (17-25 Yearsage) of Punjab Medical College Faisalabad (residing in hostel almost on a uniform diet) were evaluated for serumiron and zinc status. The estimation of serum iron and zinc were done using an atomic absorptionspectrophotometer. The mean serum iron levels were 102.54±14.36 ug/dl 107.60± 15.96 ug/dl and 112.12+16.34ug/dl, in 17-19 years, 20-22 years and 23-25 years of age respectively. The main serum zinc levels were 75.10±12.10 ug/dl, 78.40+ 12.90 ug/dl and 79.90± 12.20 ug/dl in different age groups. When the data was evaluatedaccording to the sex, it was found that serum iron and zinc levels in males were 108.40±16.42 ug/dl and79.62±14.22 ug/dl respectively. Similarly the levels were 99.68± 13.46 ug/dl and 72.52+8.76 ug/dl in females.
M. Zahoor Ul Hassan Dogar
The Professional Medical Journal , 1999,
Abstract: OBJECTIVE: To find out ascorbic acid deficiency as a possible causative factor in development ofessential hypertension. DESIGN: Prospective study. SETTING: Punjab Institute of Cardiology, Lahore.PATIENTS AND METHODS: Fifty two male patients of essential hypertension (mild and moderate)between 40-55 years age were selected. Thirty one other healthy individuals of te same age and sex were alsoincluded in the study as controls. RESULTS: The mean plasma ascorbic acid levels were found to be0.540±0.086 mg/dl, 0.372±0.068 and 0.216±0.077 mg/dl in normotensive control, mild and moderateessential hypertensive subjects, respectively. The data showed that PAA levels were significantly differentin different groups depending upon the levels of blood pressure, being highest at lowest levels of bloodpressure. The study showed that plasma ascorbic acid concentration had a moderate independent , inverseassociation with the systolic ( r = 0.891) and diastolic ( r = 0.826) blood pressure. CONCLUSIONS: Thprevalence of systolic and diastolic hypertension increase with decrease in plasma ascorbic acid. The datasuggested that plasma ascorbic acid deficiency may be one of the cause of essential hypertension in middleage male adults.
M. Zahoor ul Hassan Dogar
The Professional Medical Journal , 1998,
Abstract: The study was designed to see the effect of high doses of iron supplementation on the serum iron level. Sixtyyoung healthy students from Punjab Medical College Faisalabad were included in the study as experimentalgroup while 10 other students were enrolled as a control group for comparison. In order to study the effecton persons having almost a uniform diet, only students residing in the hostel were enrolled. Their serumlevels of iron were measured by mean of atomic absorption spectroscopy. Then the students in experimentalgroup were divided into two groups A and B, and were prescribed 150 and 300 mgs/day of iron sulphate(equivalent to 28 mg nd 56 mg of elemental iron) respectively for a period of 30 days. The serum levels ofiron were analyzed again. The mean serum iron levels were iron levels were increased from 106.5 to 124.50 ug/dl in group A and from 107.8 to 132.1 ug/dl in group B. The percentage rise was more in the group Aas compared to the group B. The results suggested that high dose iron supplementation in young healthyindividuals increases the serum iron level according to the physiological needs of the body and furtherexcess of dietary iron may go waste into the faeces.
The Professional Medical Journal , 2004,
Abstract: The present study was the continuation of the project in whichtwo different treatment protocols were applied to evaluate the efficiency of each treatment. 42 total cases weretaken divided equally into two groups. Group 1 was treated by conventional treatment DVP (Daunorubicin +Vincristine + Predinisolone). In 2 Group DVP nd & L-asparginase enzyme was applied. The effect of twotreatments on various biochemical parameters were studies by taking samples after each 0.5% months duringinduction therapy (3 months) and after induction therapy till 6 months. The results showed greater rise in bloodALT, ALP and amylase levels in Group II, as compared to the findings found in Group I. Similarly a relativerise in blood glucose, urea and bilirubin was also found in Group II as compared to Group I. It clearly indicatesthat after addition L-asparaginase although beneficial for induction therapy but resulted in deleterious effectsdevelopment on different vital organs in the body. Its use should be strictly under control of a clinicalbiochemist so that its toxicity should not over balance its benefits.
M. Zahoor-ul-Hassan Dogar
The Professional Medical Journal , 1999,
Abstract: OBJECTIVE: To find out deranged serum lipids, a cause or effect of raised blood pressure. SETTING:Punjab Institute of Cardiology Jail Road Lahore. DESIGN: Prospective study. PATIENTS ANDMETHODS: A total of ninety four male subjects between 40-55 years of age were included in the studyout of these sixty three were patients of hypertension, selected from outdoors, while the remaining thirtyone were taken from general population as control for comparison. Depending upon the levels of bloodpressure the hypertensive subjects were divided into mild (DBP € 104 mm Hg) and moderate (DBP € 114mm Hg) hypertensive groups. RESULTS: The serum levels of total cholesterol, were 182.31 mg/dl ± 28.08mg/dl in normotensive control group wile these values were 205.96 mg/dl ± 15.79 mg/dl and 261.45 mg/dl± 57.40 mg/dl in mild and moderate hypertensive subjects. The mean serum levels of HDL cholesterol inthe above three groups were 45.25 ± 4.35 mg/dl, 42.36 ± 2.76 mg/dl and 37.66 ± 3.45 mg/dl. The meanserum levels of LDL cholesterol as determined by applying the formula were 102.49 ± 29.07 mg/dl, 128.98± 21.69 mg/dl and 175.32 ± 63.72 mg/dl and man serum levels of triglycerides were 176.75 ± 42.45 mg/dl,175.79 ± 58.47 mg/dl and 200.44 ± 102.82 mg/dl in normotensive, mild and moderate hypertensive subjectsrespectively. CONCLUSIONS: The serum total cholesterol was increased in the hypertensive group ascompared to control group. The mean serum HDL cholesterol level was significantly lower in hypertensivethan in normotensive control subjects. Similarly the mean serum LDL cholesterol was higher inhypertensive as compared to normotensive subjects, while serum triglycerides showed controversial results.
The Professional Medical Journal , 2003,
M. Zahoor-ul-Hassan Dogar
The Professional Medical Journal , 1997,
The Professional Medical Journal , 2002,
Abstract: T he present study conducted by the authors showed that in 1 group out of 21 cases, 3 left and remaining total 18 stpatients of ALL who received conventional treatment 16 (92%) showed complete remission and 2 died showed nonremission.In this group 10 (62%) showed complete remission after 2 months while 6 (38%) showed remission after 3months. Similarly in 2 group out of 21 cases, 4 left and in remaining 17 patients who received conventional therapy ndwithout L-asnase 16 (94%) showed complete remission and 1 (8%) died. The 16 patients who were in remission andreceived conventional treatment along with L-asnase enzyme showed complete remission in 14 (87%) cases after 2 monthsof treatment and 2 (13%) after 3 months of duration. The estimation of various parameters were continued till 6 monthswhich showed maintenance of remission in 15 (94%) patients in 1 group and all (100%) patients in 2 group. This st ndshowed that the recommended chemotherpay without any L-asnase is less effective as induction of remission therapy whilethe addition of L-asnase enzyme in that treatment resulted in intensification of results which are maintained for longertime.
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