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Search Results: 1 - 10 of 401688 matches for " M Ikeda "
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Spatial and Temporal Analysis of Drought in Nepal using Standardized Precipitation Index and its Relationship with Climate Indices
M Sigdel,M Ikeda
Journal of Hydrology and Meteorology , 2010, DOI: 10.3126/jhm.v7i1.5617
Abstract: Drought over Nepal is studied on the basis of precipitation as a key parameter. Using monthly mean precipitation data for a period of 33 years, Standardized Precipitation Index (SPI) is produced for the drought analysis with the time scale of 3 months (SPI-3) and 12 months (SPI-12) as they are applicable for agriculture and hydrological aspects, respectively. Time-space variability is explored based on Principal Component Analysis (PCA) along with Rotated PCA (RPCA). Four rotated components were explored for both SPI-3 and SPI-12 representing climatic variability with cores over eastern, central and western Nepal separately. Droughts associated with SPI-3 occurred almost evenly over these regions. Droughts associated with SPI-12 were consistent with SPI-3 for summer, since summer precipitation dominates annual precipitation. Connection between SPI and the climate indices such as Southern Oscillation Index (SOI) and Indian Ocean Dipole Mode Index (DMI) was studied, suggesting that one of the causes for summer droughts is El Nino, while the winter droughts could be related with positive DMI. Keywords: Standardized Precipitation Index; Nepal; Principal component analysis; Drought DOI: http://dx.doi.org/10.3126/jhm.v7i1.5617 JHM 2010; 7(1): 59-74
Longitudinal study of self-awakening and sleep/wake habits in adolescents
Ikeda H, Hayashi M
Nature and Science of Sleep , 2012, DOI: http://dx.doi.org/10.2147/NSS.S33861
Abstract: ngitudinal study of self-awakening and sleep/wake habits in adolescents Original Research (1637) Total Article Views Authors: Ikeda H, Hayashi M Published Date September 2012 Volume 2012:4 Pages 103 - 109 DOI: http://dx.doi.org/10.2147/NSS.S33861 Received: 14 May 2012 Accepted: 17 July 2012 Published: 03 September 2012 Hiroki Ikeda,1 Mitsuo Hayashi2 1Department of Adult Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo; 2Department of Behavioral Sciences, Graduate School of Integrated Arts and Sciences, Hiroshima University, Hiroshima, Japan Abstract: Self-awakening is the ability to awaken without external assistance at a predetermined time. Cross-sectional studies reported that people who self-awaken have sleep/wake habits different from those of people who use external means to wake from sleep. However, no longitudinal study has examined self-awakening. The present study investigated self-awakening, both habitual and inconsistent, compared to awakening by external means in relation to sleep/wake schedules for five consecutive years in 362 students (starting at mean age 15.1 ± 0.3 years). Students who self-awakened consistently for five consecutive years (5% of all students) went to bed earlier than those who inconsistently self-awakened (mixed group, 40%) or consistently used forced awakening by external means (56%). Awakening during sleep was more frequent and sleep was lighter in the consistently self-awakened group than in the mixed and consistently forced-awakened groups. However, daytime dozing was less frequent and comfort immediately after awakening was greater for the consistently self-awakened group than for the mixed and consistently forced-awakened groups. These results indicate that the three groups have different sleep/wake habits. Previous studies of self-awakening using cross-sectional survey data may have confounded both consistent and inconsistent self-awakening habits. A longitudinal study is necessary to clarify the relationship between the self-awakening habit and sleep/wake patterns.
Longitudinal study of self-awakening and sleep/wake habits in adolescents
Ikeda H,Hayashi M
Nature and Science of Sleep , 2012,
Abstract: Hiroki Ikeda,1 Mitsuo Hayashi21Department of Adult Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo; 2Department of Behavioral Sciences, Graduate School of Integrated Arts and Sciences, Hiroshima University, Hiroshima, JapanAbstract: Self-awakening is the ability to awaken without external assistance at a predetermined time. Cross-sectional studies reported that people who self-awaken have sleep/wake habits different from those of people who use external means to wake from sleep. However, no longitudinal study has examined self-awakening. The present study investigated self-awakening, both habitual and inconsistent, compared to awakening by external means in relation to sleep/wake schedules for five consecutive years in 362 students (starting at mean age 15.1 ± 0.3 years). Students who self-awakened consistently for five consecutive years (5% of all students) went to bed earlier than those who inconsistently self-awakened (mixed group, 40%) or consistently used forced awakening by external means (56%). Awakening during sleep was more frequent and sleep was lighter in the consistently self-awakened group than in the mixed and consistently forced-awakened groups. However, daytime dozing was less frequent and comfort immediately after awakening was greater for the consistently self-awakened group than for the mixed and consistently forced-awakened groups. These results indicate that the three groups have different sleep/wake habits. Previous studies of self-awakening using cross-sectional survey data may have confounded both consistent and inconsistent self-awakening habits. A longitudinal study is necessary to clarify the relationship between the self-awakening habit and sleep/wake patterns.Keywords: habitual self-awakening, sleep/wake pattern, adolescent
Dynamic Characteristics of Selemion CMV-Based IPMC Actuators in High Humidity Environment  [PDF]
H. Ngetha, M. Sasaki, H. Tamagawa, S. Ito, K. Ikeda
Journal of Computer and Communications (JCC) , 2014, DOI: 10.4236/jcc.2014.211006
Abstract:

Electrically-induced bending of Selemion IPMC is caused by the charge induced into the IPMC. This induced charge quantity is susceptible to the absolute humidity of environment. There are two types of charges, the charge causing bending and the rest of charge that causes no bending. In the high humidity environments, where absolute humidity is above 10 gm-3, the quantity of charge causing no bending accounts for the large part of whole charge induced into the Selemion IPMC, while quantity of such charge is negligibly small at the absolute humidity of less than 10 gm-3. Estimating the quantity of those two types of charges individually, we successively analyzed the bending stability of Selemion IPMC at the absolute humidity above 10 gm-3. Consequently, we deduced the following conclusions. 1) There exists a large time delay in the current in response to the voltage input, 2) Current is highly dumping, and 3) Bending behavior is marginally stable under the input of any frequency.

Molecular Cloning of cDNAs Encoding the Proteolipid Subunit of the Vacuolar H+-ATPase of Acetabularia acetabulum
M. Habibur Rahman,Mikiko Ikeda
Pakistan Journal of Biological Sciences , 2002,
Abstract: Three cDNAs (named pVC1, pVC2 and pVC3) have been isolated from a giant alga, Acetabularia acetabulum that encoded the N, N′- icyclohexylcarbodimide-binding 16 kDa proteolipid subunit of V-ATPase. The open reading frames of pVC1, pVC2 and pVC3 predicted the polypeptides of 164, 167 and 168 amino acids with the molecular masses of 16.5, 16.7 and 16.8 kDa, respectively. Seventy nine percent identity between pVC1 and pVC2 or pVC3 and 95% identity between pVC2 and pVC3 was observed. PVC1 and pVC2/pVC3 showed extensive divergences in their 3′ -untranslated region, while pVC2 and pVC3 possessed the same 3′ -untranslated region. The deduced amino acid sequences of the three cDNA clones showed extensive similarities with that of proteolipids of oat (75 to 80%), bovine (55%) and yeast (55%) V-ATPase. Based on hydropathy plot, four membrane-spanning domains were predicted, in which domain IV was especially conserved among different species. This domain showed 96-100% identity in amino acid sequences between the A. acetabulum and the oat proteolipid in which a glutamate residue is included, the putative N, N′-dicyclohexylcarbodimide-binding residue.
Defects in Actin Dynamics Lead to an Autoinflammatory Condition through the Upregulation of CXCL5
Angela M. Verdoni, Richard S. Smith, Akihiro Ikeda, Sakae Ikeda
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0002701
Abstract: Background Destrin (DSTN) is a member of the ADF/cofilin family of proteins and is an important regulator of actin dynamics. The primary function of destrin is to depolymerize filamentous actin into its monomeric form and promote filament severing. While progress has been made in understanding the biochemical functions of the ADF/cofilin proteins, the study of an animal model for cells deficient for DSTN provides an opportunity to investigate the physiological processes regulated by proper actin dynamics in vivo. A spontaneous mouse mutant, corneal disease 1(corn1), is deficient for DSTN, which causes epithelial hyperproliferation and neovascularization in the cornea. Dstncorn1 mice exhibit an actin dynamics defect in the cornea as evidenced by the formation of actin stress fibers in the epithelial cells. Previously, we observed a significant infiltration of leukocytes into the cornea of Dstncorn1 mice as well as the upregulation of proinflammatory molecules. In this study, we sought to characterize this inflammatory condition and explore the physiological mechanism through which a loss of Dstn function leads to inflammation. Methodology/Principal Findings Through immunofluorescent analyses, we observed a significant recruitment of neutrophils and macrophages to the Dstncorn1 cornea, demonstrating that the innate immune system is spontaneously activated in this mutant. The inflammatory chemokine, CXCL5, was ectopically expressed in the corneal epithelial cells of Dstncorn1 mice, and targeting of the receptor for this chemokine inhibited neutrophil recruitment. An inflammatory reaction was not observed in the cornea of allelic mutant strain, Dstncorn1-2J, which has a milder defect in actin dynamics in the corneal epithelial cells. Conclusions/Significance This study shows that severe defects in actin dynamics lead to an autoinflammatory condition that is mediated by the expression of CXC chemokines.
New sepsis-related marker: endotoxin activity assay
T Ikeda, K Ikeda, H Taniuchi, M Hiramatsu, S Suda
Critical Care , 2010, DOI: 10.1186/cc9115
Abstract: The EAA was studied in a cohort of 153 septic patients admitted to the ICU. At the same time, IL-6 (chemiluminescent enzyme immunoassay), C-reactive protein (CRP), procalcitonin (PCT, chemiluminescent enzyme immunoassay) and plasminogen activator inhibitor-1 (PAI-1, latex photometric immunoassay) were measured within 24 hours after ICU admission. The patients were divided into the following three groups: L group: EAA < 0.4, M group: 0.4 ≤ EAA < 0.6, H group: 0.6 ≤ EAA. Nonrepeated-measures ANOVA was used to compare over three groups or conditions. Statistical significance was assumed for values of P < 0.05. Normally distributed data are presented as mean ± SD, and abnormally distributed data are presented as median values.Of the 153 patients, the L group contained 61 patients, M group 41 patients, and H group 51 patients, respectively. On the day of ICU admission, the rate of EAA ≥0.4 was 60.1% (MEDIC study: 57.2%). APACHE score in the L group was 21.0 ± 7.9, M group 24.8 ± 8.4, H group 26.4 ± 8.9, and SOFA score in the L group was 8.2 ± 4.3, M group 8.9 ± 4.1, H group 9.5 ± 4.3, respectively. There was no statistically significant difference among the groups. The median value of PCT in the L group was 1.1 ng/ml, M group 5.9 ng/ml, H group 8.5 ng/ml, respectively. PCT values of the M and H groups were significantly higher than those of the L group. Median IL-6 level of the H group was significantly higher than that of the L group (H group: 2,635 pg/ml, L group: 177 pg/ml).EAA has no significant correlation with other sepsis-related markers, but may be associated with body insults (inflammation or infection).
Sentinel Lymph Node Biopsy as Guidance for Lateral Neck Dissection in Patients with Papillary Thyroid Carcinoma  [PDF]
Yoshifumi Ikeda
Surgical Science (SS) , 2011, DOI: 10.4236/ss.2011.22012
Abstract: Introduction: The surgical management of lateral lymph nodes in differentiated thyroid carcinoma is controversies. Therefore, we analyzed whether sentinel lymph nodes (SLN) biopsy of the first draining nodes in the jugulo-carotid chain is an accurate technique to select patients with true-positive but nonpalpable lymph nodes for selective lateral node dissection. Materials and Methods: From January 2009 to December 2009, 12 patients with solitary papillary carcinoma measuring 2 cm by ultrasonography were included in this study. After the thyroid gland was exposed to avoid injuring the lateral thyroid lymphatic connection, approximately 0.2 ml of 5mg/ml indocyanine green was injected into the parenchyma of upper and lower thyroid gland. Some stained lymph nodes in the jugulo-carotid chain could be identified following the stained lymphatic duct and dissected as the SLN. After that, thyroidectomy with modified neck dissection was performed. Results: The mean tumor size was 22.1 ± 4.6 mm. Identification and biopsy of stained SLN in the ipsilateral jugulo-carotid chain was successful in all 12 cases. In 6 cases, histopathological analysis of SLNs revealed metastases of the papillary thyroid carcinoma. Among them, 2 cases had additional metastatic lymph nodes in the ipsilateral compartment. Of the 6 patients who had negative lymph node metastasis (LNM) in SLNs, all patients had negative LNM in the ipsilateral compartment. Conclusions: The method may be helpful in the detection of true-positive but nonpalpable lymph nodes and may support a decision to perform a selective lateral node dissection in patients with papillary thyroid carcinoma.
Charmonium spectra and dispersion relation with improved Bayesian analysis in lattice QCD
A. Ikeda,M. Asakawa,M. Kitazawa
Physics , 2014,
Abstract: We study the charmonium spectral functions at finite momentum and the dispersion relation of $\eta_c$ at finite temperature. For the analysis of the spectral function, we use an extended maximum entropy method (MEM). We perform the MEM analysis for the product space of Euclidean correlators in different channels or momenta to incorporate information encoded in correlations among the Euclidean correlators in MEM. We find that this method can improve the error of the reconstructed spectral images. To study the dispersion relation, we introduce a definition of the peak position in the spectral image in which the associated error can be estimated on the basis of MEM. We find that the dispersion relation of $\eta_c$ at finite temperature follows the Lorentz invariant form even near the dissociation temperature $T\simeq1.7T_c$.
Representation of the n-th derivative of the normal PDF using Bernoulli numbers and gamma function
M. A. de Oliveira,R. H. Ikeda
Applied Mathematical Sciences , 2012,
Abstract:
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